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The map label for this gene is csd [H]

Identifier: 39996966

GI number: 39996966

Start: 2044085

End: 2045227

Strand: Reverse

Name: csd [H]

Synonym: GSU1868

Alternate gene names: 39996966

Gene position: 2045227-2044085 (Counterclockwise)

Preceding gene: 39996967

Following gene: 39996965

Centisome position: 53.62

GC content: 64.74

Gene sequence:

>1143_bases
ATGTCAGTATATCTGGATAATGCCGCCACTTCCTTTCCCAAGCCCGATGCTGTCTACGAAGCCGTTGACTACGCCCTGCG
CCGCGTGGGGGTCGGTCCCGGCAGGGGAGGGTACCGGCGGAGCATCGAGGCGACACGGATAGTGTTCGAGACGCGTGAGG
CGGTGGCAACCCTGCTGGGGGTGGCCGATTCCTCCCGCGTGGTGTTTACCCACAGTGCCACCGAAGCGCTCAATCTGGCG
GTTTCGGGACTCCTCTCCCCCGGCGACCACGTGGTTACCACCACCGTGGAGCACAACTCTCTGGTCAGGCCGCTCCATGC
AGCGTCGGGGCGGGGTGTGGAAGTGACCAGTGTTGCTGCCGACCGTCGGGGATTCGTTACCCCGGACGCCGTTGCGGCAG
CTATGAGGCCAAACACGCGTCTCGTGGCCCTTTCCCACTGTTCCAACGTTACCGGTGCGCTGCAGCCCGTTGAAGAGATC
GGCGCTGAAGTGAAAAAGCGGGGCGCCCTGCTGTTGGTGGATGCGGCCCAGTCTGCCGGCATGATTCCCCTGGATGCACC
GGCAATCGGCATAGATCTGCTGGCGGCACCCGGACATAAGGGACTCTTCGGGCCCCAGGGAACCGGCATCCTCTACGTGG
CCGATGGGGTCGAGCTCACGCCGCTCATGGTGGGGGGGACCGGCGTCCACTCTTCCGACGAGGAACAGCCGGCCGCCATG
CCCGAGCGGTACGAGAGCGGCACCCTCAACACTCCCGGCATCGCCGGCCTCGGGGCGGGGGTGGCATTCATCGAGCGGAC
GGGGATTTCTGCCATCAGGGAGCGGGAAACCTCTCTGGTCCGGCAGATACTGGAAGGGCTTGCCGGCATGCGACGGGTAA
CCGTTCACGGCCCGGCCGCTGACGAACCCCGCGGGAGCGTCGTCAGCTTTTCCGCCACGGACACGGATCCGCAGACAATC
GGTTTCCGCCTTGACCACGACCACGACATCAGCGTCAGAGTGGGCCTCCACTGTGCACCCTCGGCCCACAGGACCATCGG
AACCTATCCCACGGGGACGGTGAGGGTGAGCCCCGGTTTTTTTACCACCGACAACGAGGTGGAGCTCTTTCTGCGTGCTC
TTCGCGAGATTGTCGGTGGATGA

Upstream 100 bases:

>100_bases
CGGGGGATGGTTCTGGTGGCGCCGGTACTCGACTCGGCCCCTCTGCCCGCTGTCCCGAATTCCGTTGCCAAATGACCGGG
CTGCGTGCTAATTTTTTCTC

Downstream 100 bases:

>100_bases
GAAAGGTGGCAGCCGTGAAAGGTAAAGGTATGCCGGTGTTCGTCGCAGGTGTGCGTGCCGCCGCCGCGGCTTTTGTCCTG
CTTCTCGCTGTTGCCGGCTG

Product: aminotransferase, class V

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 380; Mature: 379

Protein sequence:

>380_residues
MSVYLDNAATSFPKPDAVYEAVDYALRRVGVGPGRGGYRRSIEATRIVFETREAVATLLGVADSSRVVFTHSATEALNLA
VSGLLSPGDHVVTTTVEHNSLVRPLHAASGRGVEVTSVAADRRGFVTPDAVAAAMRPNTRLVALSHCSNVTGALQPVEEI
GAEVKKRGALLLVDAAQSAGMIPLDAPAIGIDLLAAPGHKGLFGPQGTGILYVADGVELTPLMVGGTGVHSSDEEQPAAM
PERYESGTLNTPGIAGLGAGVAFIERTGISAIRERETSLVRQILEGLAGMRRVTVHGPAADEPRGSVVSFSATDTDPQTI
GFRLDHDHDISVRVGLHCAPSAHRTIGTYPTGTVRVSPGFFTTDNEVELFLRALREIVGG

Sequences:

>Translated_380_residues
MSVYLDNAATSFPKPDAVYEAVDYALRRVGVGPGRGGYRRSIEATRIVFETREAVATLLGVADSSRVVFTHSATEALNLA
VSGLLSPGDHVVTTTVEHNSLVRPLHAASGRGVEVTSVAADRRGFVTPDAVAAAMRPNTRLVALSHCSNVTGALQPVEEI
GAEVKKRGALLLVDAAQSAGMIPLDAPAIGIDLLAAPGHKGLFGPQGTGILYVADGVELTPLMVGGTGVHSSDEEQPAAM
PERYESGTLNTPGIAGLGAGVAFIERTGISAIRERETSLVRQILEGLAGMRRVTVHGPAADEPRGSVVSFSATDTDPQTI
GFRLDHDHDISVRVGLHCAPSAHRTIGTYPTGTVRVSPGFFTTDNEVELFLRALREIVGG
>Mature_379_residues
SVYLDNAATSFPKPDAVYEAVDYALRRVGVGPGRGGYRRSIEATRIVFETREAVATLLGVADSSRVVFTHSATEALNLAV
SGLLSPGDHVVTTTVEHNSLVRPLHAASGRGVEVTSVAADRRGFVTPDAVAAAMRPNTRLVALSHCSNVTGALQPVEEIG
AEVKKRGALLLVDAAQSAGMIPLDAPAIGIDLLAAPGHKGLFGPQGTGILYVADGVELTPLMVGGTGVHSSDEEQPAAMP
ERYESGTLNTPGIAGLGAGVAFIERTGISAIRERETSLVRQILEGLAGMRRVTVHGPAADEPRGSVVSFSATDTDPQTIG
FRLDHDHDISVRVGLHCAPSAHRTIGTYPTGTVRVSPGFFTTDNEVELFLRALREIVGG

Specific function: Cysteine Desulfurases Mobilize The Sulfur From L- Cysteine To Yield L-Alanine, An Essential Step In Sulfur Metabolism For Biosynthesis Of A Variety Of Sulfur-Containing Biomolecules. Component Of The Suf Operon, Which Is Activated And Required Under Speci

COG id: COG0520

COG function: function code E; Selenocysteine lyase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. Csd subfamily [H]

Homologues:

Organism=Homo sapiens, GI32307132, Length=388, Percent_Identity=28.3505154639175, Blast_Score=126, Evalue=3e-29,
Organism=Homo sapiens, GI156713448, Length=439, Percent_Identity=26.6514806378132, Blast_Score=96, Evalue=6e-20,
Organism=Escherichia coli, GI1787970, Length=385, Percent_Identity=29.6103896103896, Blast_Score=153, Evalue=1e-38,
Organism=Escherichia coli, GI48994898, Length=397, Percent_Identity=28.463476070529, Blast_Score=136, Evalue=3e-33,
Organism=Escherichia coli, GI1789175, Length=393, Percent_Identity=29.7709923664122, Blast_Score=131, Evalue=9e-32,
Organism=Caenorhabditis elegans, GI25143064, Length=387, Percent_Identity=28.1653746770026, Blast_Score=115, Evalue=5e-26,
Organism=Caenorhabditis elegans, GI17533177, Length=208, Percent_Identity=31.7307692307692, Blast_Score=95, Evalue=6e-20,
Organism=Caenorhabditis elegans, GI193211090, Length=328, Percent_Identity=25.3048780487805, Blast_Score=69, Evalue=4e-12,
Organism=Saccharomyces cerevisiae, GI6319831, Length=393, Percent_Identity=27.735368956743, Blast_Score=125, Evalue=1e-29,
Organism=Drosophila melanogaster, GI20129463, Length=384, Percent_Identity=29.1666666666667, Blast_Score=119, Evalue=5e-27,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000192
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR015422 [H]

Pfam domain/function: PF00266 Aminotran_5 [H]

EC number: =2.8.1.7 [H]

Molecular weight: Translated: 39735; Mature: 39604

Theoretical pI: Translated: 6.09; Mature: 6.09

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
2.1 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
1.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSVYLDNAATSFPKPDAVYEAVDYALRRVGVGPGRGGYRRSIEATRIVFETREAVATLLG
CEEEECCCCCCCCCCHHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHH
VADSSRVVFTHSATEALNLAVSGLLSPGDHVVTTTVEHNSLVRPLHAASGRGVEVTSVAA
CCCCCEEEEEECHHHHHHHHHHHCCCCCCEEEEEEECCCCHHCHHHHCCCCCEEEEEECC
DRRGFVTPDAVAAAMRPNTRLVALSHCSNVTGALQPVEEIGAEVKKRGALLLVDAAQSAG
CCCCCCCHHHHHHHCCCCCEEEEEECCCCCCHHHHHHHHHHHHHHHCCCEEEEECCCCCC
MIPLDAPAIGIDLLAAPGHKGLFGPQGTGILYVADGVELTPLMVGGTGVHSSDEEQPAAM
CCEECCCCCCEEEEECCCCCCCCCCCCCEEEEEECCCEEEEEEEECCCCCCCCCCCCCCC
PERYESGTLNTPGIAGLGAGVAFIERTGISAIRERETSLVRQILEGLAGMRRVTVHGPAA
CHHHCCCCCCCCCCCHHCCCHHHHHHCCHHHHHHHHHHHHHHHHHHHCCCEEEEEECCCC
DEPRGSVVSFSATDTDPQTIGFRLDHDHDISVRVGLHCAPSAHRTIGTYPTGTVRVSPGF
CCCCCCEEEEECCCCCCCEEEEEECCCCCEEEEEEEEECCCCCCEECCCCCCEEEECCCE
FTTDNEVELFLRALREIVGG
EECCCHHHHHHHHHHHHHCC
>Mature Secondary Structure 
SVYLDNAATSFPKPDAVYEAVDYALRRVGVGPGRGGYRRSIEATRIVFETREAVATLLG
EEEECCCCCCCCCCHHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHH
VADSSRVVFTHSATEALNLAVSGLLSPGDHVVTTTVEHNSLVRPLHAASGRGVEVTSVAA
CCCCCEEEEEECHHHHHHHHHHHCCCCCCEEEEEEECCCCHHCHHHHCCCCCEEEEEECC
DRRGFVTPDAVAAAMRPNTRLVALSHCSNVTGALQPVEEIGAEVKKRGALLLVDAAQSAG
CCCCCCCHHHHHHHCCCCCEEEEEECCCCCCHHHHHHHHHHHHHHHCCCEEEEECCCCCC
MIPLDAPAIGIDLLAAPGHKGLFGPQGTGILYVADGVELTPLMVGGTGVHSSDEEQPAAM
CCEECCCCCCEEEEECCCCCCCCCCCCCEEEEEECCCEEEEEEEECCCCCCCCCCCCCCC
PERYESGTLNTPGIAGLGAGVAFIERTGISAIRERETSLVRQILEGLAGMRRVTVHGPAA
CHHHCCCCCCCCCCCHHCCCHHHHHHCCHHHHHHHHHHHHHHHHHHHCCCEEEEEECCCC
DEPRGSVVSFSATDTDPQTIGFRLDHDHDISVRVGLHCAPSAHRTIGTYPTGTVRVSPGF
CCCCCCEEEEECCCCCCCEEEEEECCCCCEEEEEEEEECCCCCCEECCCCCCEEEECCCE
FTTDNEVELFLRALREIVGG
EECCCHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9371463 [H]