Click here to switch to the map view.

The map label for this gene is kamA [H]

Identifier: 39996853

GI number: 39996853

Start: 1916898

End: 1917959

Strand: Reverse

Name: kamA [H]

Synonym: GSU1754

Alternate gene names: 39996853

Gene position: 1917959-1916898 (Counterclockwise)

Preceding gene: 39996854

Following gene: 39996850

Centisome position: 50.29

GC content: 62.15

Gene sequence:

>1062_bases
ATGGAAACCTGGCGGCGGCTGCTCGCCGATGCAGTCACCACAGCCGATGAGATTACCGAGCGGTTCGGGATCGACGCCGG
GCAGCTCGCGCCGGTTATACGCCGCTATCCGATGCGGATCACTCCCGGCTACCTGCGTCTTGTGGAAGCGCCGGGAGATC
CGATCTGGCGACAATGCATTCCCGATCCGGCCGAACTGTGCGACGACCAGCAGTCCGACCCCCTGCACGAGGAGCGTCTC
TCGCCGGTGCCGGGGCTCATCCATCGTTATCCTGATCGCGTCGTTTGGGTTGTGTCGGGGGAGTGCGCGGTCTACTGCCG
TTTCTGCATGCGGAAGCGACAGGTGGGGTGTATGACCTCCCGCCACTGTGAAGATCCTTTCGGCGAACCGCTGCGCTACA
TTGCCGAAACGCCGGCGATTCGCGACGTGATCCTGTCGGGCGGAGATCCGCTTCTGCTGGACGATGAGCGGCTGGAGGAA
ATCCTTGCCCGACTTGCTGCCATTCCGCACGTGGAAATGGTCCGCATCGGGACCCGAACCCCCGTTACGCTGCCCGAGCG
AATCACGGCAAGGCTCTGTCGCATGCTCAAACGGTACCATCCCCTCTATGTGAACACCCATTTCAATCATCCCCGGGAGA
TCACCGCCGAGGCGGCCAAGGCATGTGCACGGCTTGCCGACGCAGGCATCCCCTTGGGCAACCAGTCCGTGCTCCTGGCC
GACGTTAATGATGACCCGGCTGTGATGACACGGCTCATGCAACTGCTTCTTTCCATCCGGGTCCGCCCTTACTACATCCA
TCAGATGGACCTTGTTCGGGGCACAGGACACTTCCGGACGCCGGTGGCAACAGGGCTGGAGATTCTCACGGCATTGCGGG
GAAACACGTCGGGCATGGCCACGCCCCACTACGTAATCGACGCACCAGGGGGCAAGGGGAAGATTCCGTTGCTTCCGGAC
TGCATAAGCCGTCGGGGTGACCTGTGGCTGTTACGCACCTACACGGGGGAAACCATCGAATACCGTGATGTGGGGCAGCC
GGCTACAGTTCTTCCGGGGTGA

Upstream 100 bases:

>100_bases
GCGCCCTGGAGGTCTAGCGCCGGCAGCCAGCATGCATGCCGATGCCAGAGGCGGGGACCGGTGTCTCCGCCTCTGTCCGT
TTGCGGGAGGAGCAGAACGT

Downstream 100 bases:

>100_bases
AGGCGACTACGTCGTCAATGGAATCAAGATCGAGGAGCAGCATCACCATGCGGTCAATGCCGAGGGCGATGCCGGCGGTG
GGCGGCAGGTGGTGGAGTTC

Product: L-lysine 2,3-aminomutase

Products: NA

Alternate protein names: LAM; KAM [H]

Number of amino acids: Translated: 353; Mature: 353

Protein sequence:

>353_residues
METWRRLLADAVTTADEITERFGIDAGQLAPVIRRYPMRITPGYLRLVEAPGDPIWRQCIPDPAELCDDQQSDPLHEERL
SPVPGLIHRYPDRVVWVVSGECAVYCRFCMRKRQVGCMTSRHCEDPFGEPLRYIAETPAIRDVILSGGDPLLLDDERLEE
ILARLAAIPHVEMVRIGTRTPVTLPERITARLCRMLKRYHPLYVNTHFNHPREITAEAAKACARLADAGIPLGNQSVLLA
DVNDDPAVMTRLMQLLLSIRVRPYYIHQMDLVRGTGHFRTPVATGLEILTALRGNTSGMATPHYVIDAPGGKGKIPLLPD
CISRRGDLWLLRTYTGETIEYRDVGQPATVLPG

Sequences:

>Translated_353_residues
METWRRLLADAVTTADEITERFGIDAGQLAPVIRRYPMRITPGYLRLVEAPGDPIWRQCIPDPAELCDDQQSDPLHEERL
SPVPGLIHRYPDRVVWVVSGECAVYCRFCMRKRQVGCMTSRHCEDPFGEPLRYIAETPAIRDVILSGGDPLLLDDERLEE
ILARLAAIPHVEMVRIGTRTPVTLPERITARLCRMLKRYHPLYVNTHFNHPREITAEAAKACARLADAGIPLGNQSVLLA
DVNDDPAVMTRLMQLLLSIRVRPYYIHQMDLVRGTGHFRTPVATGLEILTALRGNTSGMATPHYVIDAPGGKGKIPLLPD
CISRRGDLWLLRTYTGETIEYRDVGQPATVLPG
>Mature_353_residues
METWRRLLADAVTTADEITERFGIDAGQLAPVIRRYPMRITPGYLRLVEAPGDPIWRQCIPDPAELCDDQQSDPLHEERL
SPVPGLIHRYPDRVVWVVSGECAVYCRFCMRKRQVGCMTSRHCEDPFGEPLRYIAETPAIRDVILSGGDPLLLDDERLEE
ILARLAAIPHVEMVRIGTRTPVTLPERITARLCRMLKRYHPLYVNTHFNHPREITAEAAKACARLADAGIPLGNQSVLLA
DVNDDPAVMTRLMQLLLSIRVRPYYIHQMDLVRGTGHFRTPVATGLEILTALRGNTSGMATPHYVIDAPGGKGKIPLLPD
CISRRGDLWLLRTYTGETIEYRDVGQPATVLPG

Specific function: Catalyzes the interconversion of L-alpha-lysine and L- beta-lysine [H]

COG id: COG1509

COG function: function code E; Lysine 2,3-aminomutase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the KamA family [H]

Homologues:

Organism=Escherichia coli, GI1790589, Length=326, Percent_Identity=35.8895705521472, Blast_Score=184, Evalue=9e-48,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003739
- InterPro:   IPR022459
- InterPro:   IPR007197 [H]

Pfam domain/function: PF04055 Radical_SAM [H]

EC number: =5.4.3.2 [H]

Molecular weight: Translated: 39609; Mature: 39609

Theoretical pI: Translated: 7.02; Mature: 7.02

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.8 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
5.7 %Cys+Met (Translated Protein)
2.8 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
5.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
METWRRLLADAVTTADEITERFGIDAGQLAPVIRRYPMRITPGYLRLVEAPGDPIWRQCI
CCHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHCCCCCCCHHEEEEECCCCHHHHHHC
PDPAELCDDQQSDPLHEERLSPVPGLIHRYPDRVVWVVSGECAVYCRFCMRKRQVGCMTS
CCHHHHCCCCCCCCCHHHHCCCCCHHHHHCCCCEEEEECCCHHHHHHHHHHHHHHCHHHH
RHCEDPFGEPLRYIAETPAIRDVILSGGDPLLLDDERLEEILARLAAIPHVEMVRIGTRT
HCCCCCCCHHHHHHHCCCHHHHHHHCCCCCEEECHHHHHHHHHHHHHCCCEEEEEECCCC
PVTLPERITARLCRMLKRYHPLYVNTHFNHPREITAEAAKACARLADAGIPLGNQSVLLA
CCCCHHHHHHHHHHHHHHCCCEEEECCCCCCHHHHHHHHHHHHHHHHCCCCCCCCCEEEE
DVNDDPAVMTRLMQLLLSIRVRPYYIHQMDLVRGTGHFRTPVATGLEILTALRGNTSGMA
ECCCCHHHHHHHHHHHHHHCCCEEEEEHHHHHHCCCCCCCHHHHHHHHHHHHCCCCCCCC
TPHYVIDAPGGKGKIPLLPDCISRRGDLWLLRTYTGETIEYRDVGQPATVLPG
CCCEEEECCCCCCCCCCCHHHHCCCCCEEEEEECCCCEEEECCCCCCCCCCCC
>Mature Secondary Structure
METWRRLLADAVTTADEITERFGIDAGQLAPVIRRYPMRITPGYLRLVEAPGDPIWRQCI
CCHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHCCCCCCCHHEEEEECCCCHHHHHHC
PDPAELCDDQQSDPLHEERLSPVPGLIHRYPDRVVWVVSGECAVYCRFCMRKRQVGCMTS
CCHHHHCCCCCCCCCHHHHCCCCCHHHHHCCCCEEEEECCCHHHHHHHHHHHHHHCHHHH
RHCEDPFGEPLRYIAETPAIRDVILSGGDPLLLDDERLEEILARLAAIPHVEMVRIGTRT
HCCCCCCCHHHHHHHCCCHHHHHHHCCCCCEEECHHHHHHHHHHHHHCCCEEEEEECCCC
PVTLPERITARLCRMLKRYHPLYVNTHFNHPREITAEAAKACARLADAGIPLGNQSVLLA
CCCCHHHHHHHHHHHHHHCCCEEEECCCCCCHHHHHHHHHHHHHHHHCCCCCCCCCEEEE
DVNDDPAVMTRLMQLLLSIRVRPYYIHQMDLVRGTGHFRTPVATGLEILTALRGNTSGMA
ECCCCHHHHHHHHHHHHHHCCCEEEEEHHHHHHCCCCCCCHHHHHHHHHHHHCCCCCCCC
TPHYVIDAPGGKGKIPLLPDCISRRGDLWLLRTYTGETIEYRDVGQPATVLPG
CCCEEEECCCCCCCCCCCHHHHCCCCCEEEEEECCCCEEEECCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10629195 [H]