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The map label for this gene is yjeP [H]

Identifier: 39996822

GI number: 39996822

Start: 1886072

End: 1887709

Strand: Reverse

Name: yjeP [H]

Synonym: GSU1723

Alternate gene names: 39996822

Gene position: 1887709-1886072 (Counterclockwise)

Preceding gene: 308513306

Following gene: 39996818

Centisome position: 49.49

GC content: 57.69

Gene sequence:

>1638_bases
ATGCGCTTCGTGATCGTGATAGTCGCCCTGCTGGCTGGCTTGCTGGCGACCCCGCTGTGTTCGGCAGACATGCCGGTGGT
GAGCGAGAATTCCCTGGCCCAGGCTCCGGCGGCAGTTACCTTGGGCGGCAAGCCTCTCTTTTACGTGCGGCATCGCGCCC
TTTCGCTGATGCCCCGGGAGCGGGCCGCTCTCATCTCCGAGCGGTTGGTGCGCCTTGCGCGTTCGCCTCTGGTGTCTCCG
GCAGATGTTCATGCCGTTGAGGCCGAGACGGTTACCGATATCATCGCGGGTGACACGCTGATCCTGACCGTAACCGATGA
CGATGCCCGTGCCGAAGGGAAGACAAGGCACGAACTGGTGCAATCGTATAGTGACGTTATTCGCAAGGCGTTGGAGGACT
ATCACAACGACTATTCGGTCCACAGCCTGATCAAGGGAGCCGGCTTAACCATTGCTGTCACGATCCTGCTGGCTCTGCTG
CTCCTGATCATCAAGCGGTCGTACCCCGTGGTGCGAAACACCATCGAGTCATGGAGCGGTACCAGGATCCGGGATCTGAA
AATCCAGTCTTTCGAAATTGTCTCGGCCGGTCGGATAACTCAGGTCATCCTCAGCGCGGTCCGGTGGATCAGGATCCTGG
CTGTTTTCCTGCTCGTGTGCGTCTATCTCCTGTCGGTGCTGAGCTTTTTCCCTTGGACCAGGCGTTTTGCCCCCCTGCTC
CTGCATTACCTGACCAATCCGTTGGCAATCACGGTAAAGGCCGTGGCCGATTATCTGCCCAACCTGTTCTTCATCGCGGT
CATTGTTGTGATTGCCTACTTTATCAGCCGATTGTTGAAGGTCGTGATCGGTGAAATCGGCAAGGGCACCATAACCATTC
CCGGATTTTTCCCAGAATGGGCGGAACCGACCTACAAGATCTGCCGTTTTCTGGTGATTGCATTCGCGGTTACCGTGGCG
TTCCCCTATCTTCCCGGCTCGGAATCGCCCGCGTTCAAGGGGATCTCCATCTTTCTCGGGGTCCTCTTTTCACTGGGGTC
GACGTCGGCGGTAGCCAACGTAGTGGCGGGAATCATCATTACCTACATGCGTGCGTACCGCATTGGGGATCGGATCAAGG
TGGGGGAGACGGTGGGAGACGTTGTTGAGAAAAACCTGCTCATTACGAGGCTGAGAACGATCAAGAACGTGGACGTGACC
ATACCCAACTCGTTGCTGCTTTCCAGCCACGTGGTCAACTACAGTTCTTCGGCCCAGGAATACGGGCTGATCCTCAATAC
CAGCGTCACCATCGGGTATGACACGCCTTGGCGGCAGGTCCACGAGCTGTTGATCAGTGCCGCCCGCCGTACCGAGCACG
TGCTTGAGCTGCCCGAACCGTTCATTCTCCAGACAGCGCTCAACGATTTCTACGTGACCTATGAACTGAACGCTTACACG
GACAAGCCGAACCGGATGGCAAACCTGTATTCGCAGCTTCACCAGAATATTCAGGATGCGTTCAATGAGGCCGGGGTCGA
GATCATGTCGCCCCACTACTCCCAGCTGCGCGACGGCAACACGGTTACGGTTCCGGAGCAGTTCCGGCCGGCCGGCTACG
TGCCGCCATCGTTCCGGGTGAGCAAGACGGATGACTGA

Upstream 100 bases:

>100_bases
AGCTTCAGGTCCTGAACTCCGACTCGTACCGGCACCTGAAATTGCTCAATACAATTAACAGATGCCCTGGTTACAACCTC
TACCCCGTCCGGGAGGAACA

Downstream 100 bases:

>100_bases
CGGGCGGGATGCCCGATTTGATGGGAGGGTGCCAGGGCTGCGGCTGGAAAAGCTATTCCTTGAACGCTTCCAGGGTGCGG
GCGAGCTGGACGATTTTGGC

Product: mechanosensitive ion channel family protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 545; Mature: 545

Protein sequence:

>545_residues
MRFVIVIVALLAGLLATPLCSADMPVVSENSLAQAPAAVTLGGKPLFYVRHRALSLMPRERAALISERLVRLARSPLVSP
ADVHAVEAETVTDIIAGDTLILTVTDDDARAEGKTRHELVQSYSDVIRKALEDYHNDYSVHSLIKGAGLTIAVTILLALL
LLIIKRSYPVVRNTIESWSGTRIRDLKIQSFEIVSAGRITQVILSAVRWIRILAVFLLVCVYLLSVLSFFPWTRRFAPLL
LHYLTNPLAITVKAVADYLPNLFFIAVIVVIAYFISRLLKVVIGEIGKGTITIPGFFPEWAEPTYKICRFLVIAFAVTVA
FPYLPGSESPAFKGISIFLGVLFSLGSTSAVANVVAGIIITYMRAYRIGDRIKVGETVGDVVEKNLLITRLRTIKNVDVT
IPNSLLLSSHVVNYSSSAQEYGLILNTSVTIGYDTPWRQVHELLISAARRTEHVLELPEPFILQTALNDFYVTYELNAYT
DKPNRMANLYSQLHQNIQDAFNEAGVEIMSPHYSQLRDGNTVTVPEQFRPAGYVPPSFRVSKTDD

Sequences:

>Translated_545_residues
MRFVIVIVALLAGLLATPLCSADMPVVSENSLAQAPAAVTLGGKPLFYVRHRALSLMPRERAALISERLVRLARSPLVSP
ADVHAVEAETVTDIIAGDTLILTVTDDDARAEGKTRHELVQSYSDVIRKALEDYHNDYSVHSLIKGAGLTIAVTILLALL
LLIIKRSYPVVRNTIESWSGTRIRDLKIQSFEIVSAGRITQVILSAVRWIRILAVFLLVCVYLLSVLSFFPWTRRFAPLL
LHYLTNPLAITVKAVADYLPNLFFIAVIVVIAYFISRLLKVVIGEIGKGTITIPGFFPEWAEPTYKICRFLVIAFAVTVA
FPYLPGSESPAFKGISIFLGVLFSLGSTSAVANVVAGIIITYMRAYRIGDRIKVGETVGDVVEKNLLITRLRTIKNVDVT
IPNSLLLSSHVVNYSSSAQEYGLILNTSVTIGYDTPWRQVHELLISAARRTEHVLELPEPFILQTALNDFYVTYELNAYT
DKPNRMANLYSQLHQNIQDAFNEAGVEIMSPHYSQLRDGNTVTVPEQFRPAGYVPPSFRVSKTDD
>Mature_545_residues
MRFVIVIVALLAGLLATPLCSADMPVVSENSLAQAPAAVTLGGKPLFYVRHRALSLMPRERAALISERLVRLARSPLVSP
ADVHAVEAETVTDIIAGDTLILTVTDDDARAEGKTRHELVQSYSDVIRKALEDYHNDYSVHSLIKGAGLTIAVTILLALL
LLIIKRSYPVVRNTIESWSGTRIRDLKIQSFEIVSAGRITQVILSAVRWIRILAVFLLVCVYLLSVLSFFPWTRRFAPLL
LHYLTNPLAITVKAVADYLPNLFFIAVIVVIAYFISRLLKVVIGEIGKGTITIPGFFPEWAEPTYKICRFLVIAFAVTVA
FPYLPGSESPAFKGISIFLGVLFSLGSTSAVANVVAGIIITYMRAYRIGDRIKVGETVGDVVEKNLLITRLRTIKNVDVT
IPNSLLLSSHVVNYSSSAQEYGLILNTSVTIGYDTPWRQVHELLISAARRTEHVLELPEPFILQTALNDFYVTYELNAYT
DKPNRMANLYSQLHQNIQDAFNEAGVEIMSPHYSQLRDGNTVTVPEQFRPAGYVPPSFRVSKTDD

Specific function: Unknown

COG id: COG0668

COG function: function code M; Small-conductance mechanosensitive channel

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the mscS (TC 1.A.23) family [H]

Homologues:

Organism=Escherichia coli, GI2367355, Length=237, Percent_Identity=26.5822784810127, Blast_Score=77, Evalue=4e-15,
Organism=Escherichia coli, GI1786670, Length=202, Percent_Identity=24.2574257425743, Blast_Score=64, Evalue=4e-11,
Organism=Escherichia coli, GI1789291, Length=258, Percent_Identity=18.6046511627907, Blast_Score=62, Evalue=9e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR010920
- InterPro:   IPR011066
- InterPro:   IPR006685
- InterPro:   IPR006686
- InterPro:   IPR011014 [H]

Pfam domain/function: PF00924 MS_channel [H]

EC number: NA

Molecular weight: Translated: 60401; Mature: 60401

Theoretical pI: Translated: 8.63; Mature: 8.63

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
1.1 %Met     (Translated Protein)
1.7 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
1.1 %Met     (Mature Protein)
1.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRFVIVIVALLAGLLATPLCSADMPVVSENSLAQAPAAVTLGGKPLFYVRHRALSLMPRE
CHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCHHHCCCEEEECCCCHHHHHHHHHHHCCHH
RAALISERLVRLARSPLVSPADVHAVEAETVTDIIAGDTLILTVTDDDARAEGKTRHELV
HHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHCCCEEEEEEECCCCCCCCCHHHHHH
QSYSDVIRKALEDYHNDYSVHSLIKGAGLTIAVTILLALLLLIIKRSYPVVRNTIESWSG
HHHHHHHHHHHHHHCCCHHHHHHHHCCCHHHHHHHHHHHHHHHHHCCCHHHHHHHHHCCC
TRIRDLKIQSFEIVSAGRITQVILSAVRWIRILAVFLLVCVYLLSVLSFFPWTRRFAPLL
CEEEEEEECEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHH
LHYLTNPLAITVKAVADYLPNLFFIAVIVVIAYFISRLLKVVIGEIGKGTITIPGFFPEW
HHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEECCCCCCCC
AEPTYKICRFLVIAFAVTVAFPYLPGSESPAFKGISIFLGVLFSLGSTSAVANVVAGIII
CCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHCCCHHHHHHHHHHHHH
TYMRAYRIGDRIKVGETVGDVVEKNLLITRLRTIKNVDVTIPNSLLLSSHVVNYSSSAQE
HHHHHHHCCCCEECCHHHHHHHHHHHHHHHHHHHCCCCEECCHHHHHHHHHHCCCCCHHH
YGLILNTSVTIGYDTPWRQVHELLISAARRTEHVLELPEPFILQTALNDFYVTYELNAYT
CCEEEECEEEECCCCCHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHCCEEEEEEEECCC
DKPNRMANLYSQLHQNIQDAFNEAGVEIMSPHYSQLRDGNTVTVPEQFRPAGYVPPSFRV
CCCHHHHHHHHHHHHHHHHHHHHCCCEEECCCHHHHCCCCEEECCHHCCCCCCCCCCCCC
SKTDD
CCCCC
>Mature Secondary Structure
MRFVIVIVALLAGLLATPLCSADMPVVSENSLAQAPAAVTLGGKPLFYVRHRALSLMPRE
CHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCHHHCCCEEEECCCCHHHHHHHHHHHCCHH
RAALISERLVRLARSPLVSPADVHAVEAETVTDIIAGDTLILTVTDDDARAEGKTRHELV
HHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHCCCEEEEEEECCCCCCCCCHHHHHH
QSYSDVIRKALEDYHNDYSVHSLIKGAGLTIAVTILLALLLLIIKRSYPVVRNTIESWSG
HHHHHHHHHHHHHHCCCHHHHHHHHCCCHHHHHHHHHHHHHHHHHCCCHHHHHHHHHCCC
TRIRDLKIQSFEIVSAGRITQVILSAVRWIRILAVFLLVCVYLLSVLSFFPWTRRFAPLL
CEEEEEEECEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHH
LHYLTNPLAITVKAVADYLPNLFFIAVIVVIAYFISRLLKVVIGEIGKGTITIPGFFPEW
HHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEECCCCCCCC
AEPTYKICRFLVIAFAVTVAFPYLPGSESPAFKGISIFLGVLFSLGSTSAVANVVAGIII
CCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHCCCHHHHHHHHHHHHH
TYMRAYRIGDRIKVGETVGDVVEKNLLITRLRTIKNVDVTIPNSLLLSSHVVNYSSSAQE
HHHHHHHCCCCEECCHHHHHHHHHHHHHHHHHHHCCCCEECCHHHHHHHHHHCCCCCHHH
YGLILNTSVTIGYDTPWRQVHELLISAARRTEHVLELPEPFILQTALNDFYVTYELNAYT
CCEEEECEEEECCCCCHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHCCEEEEEEEECCC
DKPNRMANLYSQLHQNIQDAFNEAGVEIMSPHYSQLRDGNTVTVPEQFRPAGYVPPSFRV
CCCHHHHHHHHHHHHHHHHHHHHCCCEEECCCHHHHCCCCEEECCHHCCCCCCCCCCCCC
SKTDD
CCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 7610040; 9278503; 3042771 [H]