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The map label for this gene is fbcH [H]

Identifier: 39996749

GI number: 39996749

Start: 1807213

End: 1808316

Strand: Reverse

Name: fbcH [H]

Synonym: GSU1649

Alternate gene names: 39996749

Gene position: 1808316-1807213 (Counterclockwise)

Preceding gene: 39996750

Following gene: 39996748

Centisome position: 47.41

GC content: 58.51

Gene sequence:

>1104_bases
ATGTCTCTGCCGGATAAACTCCGAGAATGGTTCGAAGTGCGCCTCGGTATAGCAGAACTGGTTGAGAAACGCCTGACCGG
CTATCTGCTGCCCCGCAACATCAACGCTTGGTACTCCCTGGGAAGCGTCCTGCTGGTAATCTTCGGCATCCAGGTGGTCA
CCGGCATCCTGCTTCTCATCTACTACGTTCCGGACGCGGACAAGGCATTTCGCAGCGTCACCGCCATAATGAACGACGTT
CCTTTCGGGTGGCTCATCCGGATGTGCCATGCGGTCGGTTCAAACATGATGGTGGCGGTGCTGCTGCTCCACATGCTGTC
GGTCCTGTTCATGGGGAGCTACAAGCGCCCGCGGGAACTGAACTGGCTCACGGGATTCATCCTTTTCAACCTGGTATTGG
GAATATCCCTTACCGGCTACCTCCTCCCTTGGAGCCAGCTCTCATTCTGGGCAACCACCGTGGCCACCAACAGCGCCGGC
GCCATACCGGTCATCGGCGGCTACCTGGTGGAATTCCTGCGGGGCGGCAAACTCGTCGGACCGCCGACCCTCGGCCGATT
CTTCGCCGTCCACGTGGCACTGTTACCGCTTCTTATCGCCGCGCTCATCGGAGCACATCTCTTTTTGCTTGAGCGGATCG
GCGTTTCCGCGCCTCCCTTCGGCCTCGCCAATACGCGCACCCGCTGGGCCGGGGACCGGTTCCGCCATGAATCCCATCCG
GACGGCATCCCGTTCTACCCCACCTACCTGCTACAGGATGCAACCTCCATTTTCATCTATCTTGCGCTATTCTTCGGCGT
GGTATTCTTCAATCCCTACTTGTTCTTTCCCCCCACCGCCTTTATCCCGGCCGATCCATTCAAGACCCCACCTCACATCA
AGCCGGAATGGTACTTTCTAGCAAACTATCAGACCCTCAAGGTCTTCCCCAACGAGCTGCTGGGCCTCATGGTTCAGGGG
GCGGTCATGAGCTTGCTGGCCCTGCTTCCCTTTATCGACCGCGGCGCAGAGCGGCACCCTCTCAAGCGGCCGCTTTTTCT
CGCCTGTTTTATCGGTGGCATCTGCGTTTATCTTGCCATGACCATCTGGGGGCACTACTCATGA

Upstream 100 bases:

>100_bases
GTGCCGATGGATCAGTCCTTTCGGGACCTCCGCCCAAGCCGCTCGCCCGGCTTCCTCTCGCCGTGGAAAACGGCATCGTT
ACCATCGGATAGGAGGCCAC

Downstream 100 bases:

>100_bases
GATTCGCGTTCCGTTCACGGGCCGGAGTCCCTTTCATACTTTCGATCCTTGCTCTCTTGGTTGCAACCTTGGAGCCACCG
CACGCTCATGCCCTTGAGAC

Product: cytochrome b/b6

Products: Q; ferrocytochrome c

Alternate protein names: NA

Number of amino acids: Translated: 367; Mature: 366

Protein sequence:

>367_residues
MSLPDKLREWFEVRLGIAELVEKRLTGYLLPRNINAWYSLGSVLLVIFGIQVVTGILLLIYYVPDADKAFRSVTAIMNDV
PFGWLIRMCHAVGSNMMVAVLLLHMLSVLFMGSYKRPRELNWLTGFILFNLVLGISLTGYLLPWSQLSFWATTVATNSAG
AIPVIGGYLVEFLRGGKLVGPPTLGRFFAVHVALLPLLIAALIGAHLFLLERIGVSAPPFGLANTRTRWAGDRFRHESHP
DGIPFYPTYLLQDATSIFIYLALFFGVVFFNPYLFFPPTAFIPADPFKTPPHIKPEWYFLANYQTLKVFPNELLGLMVQG
AVMSLLALLPFIDRGAERHPLKRPLFLACFIGGICVYLAMTIWGHYS

Sequences:

>Translated_367_residues
MSLPDKLREWFEVRLGIAELVEKRLTGYLLPRNINAWYSLGSVLLVIFGIQVVTGILLLIYYVPDADKAFRSVTAIMNDV
PFGWLIRMCHAVGSNMMVAVLLLHMLSVLFMGSYKRPRELNWLTGFILFNLVLGISLTGYLLPWSQLSFWATTVATNSAG
AIPVIGGYLVEFLRGGKLVGPPTLGRFFAVHVALLPLLIAALIGAHLFLLERIGVSAPPFGLANTRTRWAGDRFRHESHP
DGIPFYPTYLLQDATSIFIYLALFFGVVFFNPYLFFPPTAFIPADPFKTPPHIKPEWYFLANYQTLKVFPNELLGLMVQG
AVMSLLALLPFIDRGAERHPLKRPLFLACFIGGICVYLAMTIWGHYS
>Mature_366_residues
SLPDKLREWFEVRLGIAELVEKRLTGYLLPRNINAWYSLGSVLLVIFGIQVVTGILLLIYYVPDADKAFRSVTAIMNDVP
FGWLIRMCHAVGSNMMVAVLLLHMLSVLFMGSYKRPRELNWLTGFILFNLVLGISLTGYLLPWSQLSFWATTVATNSAGA
IPVIGGYLVEFLRGGKLVGPPTLGRFFAVHVALLPLLIAALIGAHLFLLERIGVSAPPFGLANTRTRWAGDRFRHESHPD
GIPFYPTYLLQDATSIFIYLALFFGVVFFNPYLFFPPTAFIPADPFKTPPHIKPEWYFLANYQTLKVFPNELLGLMVQGA
VMSLLALLPFIDRGAERHPLKRPLFLACFIGGICVYLAMTIWGHYS

Specific function: Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis. c1 functions as an electron donor to cytochrome c [H]

COG id: COG1290

COG function: function code C; Cytochrome b subunit of the bc complex

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein (Probable) [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 cytochrome c domain [H]

Homologues:

Organism=Homo sapiens, GI251831119, Length=327, Percent_Identity=37.9204892966361, Blast_Score=204, Evalue=9e-53,
Organism=Saccharomyces cerevisiae, GI6226529, Length=320, Percent_Identity=35.625, Blast_Score=187, Evalue=2e-48,
Organism=Saccharomyces cerevisiae, GI6226532, Length=242, Percent_Identity=35.5371900826446, Blast_Score=140, Evalue=2e-34,
Organism=Saccharomyces cerevisiae, GI6226531, Length=146, Percent_Identity=39.7260273972603, Blast_Score=102, Evalue=8e-23,
Organism=Saccharomyces cerevisiae, GI6226530, Length=136, Percent_Identity=36.0294117647059, Blast_Score=85, Evalue=2e-17,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016175
- InterPro:   IPR005798
- InterPro:   IPR005797
- InterPro:   IPR002326
- InterPro:   IPR021157
- InterPro:   IPR009056
- InterPro:   IPR016174 [H]

Pfam domain/function: PF00032 Cytochrom_B_C; PF00033 Cytochrom_B_N; PF02167 Cytochrom_C1 [H]

EC number: 1.10.2.2

Molecular weight: Translated: 41159; Mature: 41027

Theoretical pI: Translated: 9.49; Mature: 9.49

Prosite motif: PS51002 CYTB_NTER ; PS51003 CYTB_CTER

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure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HHHCCCC
>Mature Secondary Structure 
SLPDKLREWFEVRLGIAELVEKRLTGYLLPRNINAWYSLGSVLLVIFGIQVVTGILLLI
CCHHHHHHHHHHHHHHHHHHHHHHHCEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
YYVPDADKAFRSVTAIMNDVPFGWLIRMCHAVGSNMMVAVLLLHMLSVLFMGSYKRPREL
HHCCCHHHHHHHHHHHHHCCCHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHCCCCCCCHH
NWLTGFILFNLVLGISLTGYLLPWSQLSFWATTVATNSAGAIPVIGGYLVEFLRGGKLVG
HHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHCCCCCC
PPTLGRFFAVHVALLPLLIAALIGAHLFLLERIGVSAPPFGLANTRTRWAGDRFRHESHP
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCHHCCHHHCCCCCC
DGIPFYPTYLLQDATSIFIYLALFFGVVFFNPYLFFPPTAFIPADPFKTPPHIKPEWYFL
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCEEEE
ANYQTLKVFPNELLGLMVQGAVMSLLALLPFIDRGAERHPLKRPLFLACFIGGICVYLAM
ECCEEEHHCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHH
TIWGHYS
HHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: QH2; ferricytochrome c

Specific reaction: QH2 + 2 ferricytochrome c = Q + 2 ferrocytochrome c

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 2541921; 12597275 [H]