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The map label for this gene is purQ [H]

Identifier: 39996735

GI number: 39996735

Start: 1794274

End: 1795101

Strand: Direct

Name: purQ [H]

Synonym: GSU1635

Alternate gene names: 39996735

Gene position: 1794274-1795101 (Clockwise)

Preceding gene: 39996734

Following gene: 39996736

Centisome position: 47.04

GC content: 59.78

Gene sequence:

>828_bases
ATGGCAAAGGCACGAGCGATAGTTATAACCGGCAACGGCACAAACTGCGAAATGGAGGCGGCTCACGCCTGCCGCCTGGG
CGGCTTCGATGAGACCGTCATTGCCCACATATCCGATATTCTCACCGGTGAGATCCGGCTCGACGATTTCCACTTTCTCA
ATCTTACCGGCGGGTTCCTGGACGGGGACGACCTGGGGAGTGCCAAGGCCCAGGCAAACCGTTTCAGATATGCCCGGGTC
GACGACCTGGAAGAGCACCTGATCGACCAGATCATACGCTTCATTGACGCGGGCAAGCTGATCCTCGGCGTCTGCAACGG
GTTCCAGCTCATGACCAAGATGGGGCTGTTGCCTGCCGTGGACGGTGCCTATCTGGCCCAGACGGCAACACTCACCTTCA
ATGCCTGCGGCAGGTTCCAGGATCGCTGGGTGTACCTGAAGGTCGATCAGGCATCGCCGTCAATTTACACGAAAGGGGTG
GAGACGGGGCTCTATCTGCCGATACGTCACGGGGAAGGGAAGTTCGTGGTGGACAGCCCGGCAACTCTTGCCGCTATTGA
AGCGAAGCACCTGGCGGTCTTCACCTATTCCGACGAAACATATTCGGCACCGACCATGGAGTTTCCATTGAACCCCAACG
GGTCGGTCAACGCCATCGCTGCCGTCTGCAATGAATCCGGCCGGCTCATGGGCATGATGCCCCACCCCGAGGCGTTCCTC
CACCGGACCAATCATCCCCGCTGGACCCGCGAGGACCTTCCCGAAGAGGGAGATGGACTCGTCCTGTTCCGCAACGCGGC
CGACTACGCGAAGGCAAACCTGCTGTAG

Upstream 100 bases:

>100_bases
GAGGGTGACGGTTACCGGTCTTTCGGGCACCAGGGTCATCGACGCAGGGATCGACGAACTCAAGCAAGCGTGGCAGAGCC
CGCTGAGGGAGCTGTAATCA

Downstream 100 bases:

>100_bases
GGGGCGGTTTCCCGCCCACACCATTTTGGAGAGATGATGAAGCTCTACAGACCAACGGAAGAGTGCGGCATTTTCGGTAT
CTACGGCCACCCTGAGGCGG

Product: phosphoribosylaminoimidazole carboxylase, catalytic subunit

Products: NA

Alternate protein names: Phosphoribosylformylglycinamidine synthase I; FGAM synthase I [H]

Number of amino acids: Translated: 275; Mature: 274

Protein sequence:

>275_residues
MAKARAIVITGNGTNCEMEAAHACRLGGFDETVIAHISDILTGEIRLDDFHFLNLTGGFLDGDDLGSAKAQANRFRYARV
DDLEEHLIDQIIRFIDAGKLILGVCNGFQLMTKMGLLPAVDGAYLAQTATLTFNACGRFQDRWVYLKVDQASPSIYTKGV
ETGLYLPIRHGEGKFVVDSPATLAAIEAKHLAVFTYSDETYSAPTMEFPLNPNGSVNAIAAVCNESGRLMGMMPHPEAFL
HRTNHPRWTREDLPEEGDGLVLFRNAADYAKANLL

Sequences:

>Translated_275_residues
MAKARAIVITGNGTNCEMEAAHACRLGGFDETVIAHISDILTGEIRLDDFHFLNLTGGFLDGDDLGSAKAQANRFRYARV
DDLEEHLIDQIIRFIDAGKLILGVCNGFQLMTKMGLLPAVDGAYLAQTATLTFNACGRFQDRWVYLKVDQASPSIYTKGV
ETGLYLPIRHGEGKFVVDSPATLAAIEAKHLAVFTYSDETYSAPTMEFPLNPNGSVNAIAAVCNESGRLMGMMPHPEAFL
HRTNHPRWTREDLPEEGDGLVLFRNAADYAKANLL
>Mature_274_residues
AKARAIVITGNGTNCEMEAAHACRLGGFDETVIAHISDILTGEIRLDDFHFLNLTGGFLDGDDLGSAKAQANRFRYARVD
DLEEHLIDQIIRFIDAGKLILGVCNGFQLMTKMGLLPAVDGAYLAQTATLTFNACGRFQDRWVYLKVDQASPSIYTKGVE
TGLYLPIRHGEGKFVVDSPATLAAIEAKHLAVFTYSDETYSAPTMEFPLNPNGSVNAIAAVCNESGRLMGMMPHPEAFLH
RTNHPRWTREDLPEEGDGLVLFRNAADYAKANLL

Specific function: Unknown

COG id: COG0047

COG function: function code F; Phosphoribosylformylglycinamidine (FGAM) synthase, glutamine amidotransferase domain

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 glutamine amidotransferase type-1 domain [H]

Homologues:

Organism=Homo sapiens, GI31657129, Length=246, Percent_Identity=34.1463414634146, Blast_Score=119, Evalue=3e-27,
Organism=Escherichia coli, GI48994899, Length=268, Percent_Identity=37.6865671641791, Blast_Score=144, Evalue=6e-36,
Organism=Caenorhabditis elegans, GI17553022, Length=239, Percent_Identity=30.9623430962343, Blast_Score=98, Evalue=5e-21,
Organism=Saccharomyces cerevisiae, GI6321498, Length=282, Percent_Identity=29.7872340425532, Blast_Score=103, Evalue=4e-23,
Organism=Drosophila melanogaster, GI24582111, Length=238, Percent_Identity=31.5126050420168, Blast_Score=107, Evalue=7e-24,
Organism=Drosophila melanogaster, GI24582109, Length=238, Percent_Identity=31.5126050420168, Blast_Score=107, Evalue=7e-24,
Organism=Drosophila melanogaster, GI17137292, Length=238, Percent_Identity=31.5126050420168, Blast_Score=107, Evalue=7e-24,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR017926
- InterPro:   IPR010075
- InterPro:   IPR002818 [H]

Pfam domain/function: PF01965 DJ-1_PfpI [H]

EC number: =6.3.5.3 [H]

Molecular weight: Translated: 30139; Mature: 30007

Theoretical pI: Translated: 5.14; Mature: 5.14

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.8 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
4.7 %Cys+Met (Translated Protein)
1.8 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
4.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAKARAIVITGNGTNCEMEAAHACRLGGFDETVIAHISDILTGEIRLDDFHFLNLTGGFL
CCCCEEEEEECCCCCCEEHHHHEEECCCCCHHHHHHHHHHHCCEEEECCEEEEEEECCCC
DGDDLGSAKAQANRFRYARVDDLEEHLIDQIIRFIDAGKLILGVCNGFQLMTKMGLLPAV
CCCCCCCCHHHHHHEEEECCCHHHHHHHHHHHHHHCCCCEEEEHHCCHHHHHHHCCCCCC
DGAYLAQTATLTFNACGRFQDRWVYLKVDQASPSIYTKGVETGLYLPIRHGEGKFVVDSP
CCHHEEEEEEEEEECCCCCCCCEEEEEEECCCCCEEECCCCCCEEEEEEECCCCEEEECC
ATLAAIEAKHLAVFTYSDETYSAPTMEFPLNPNGSVNAIAAVCNESGRLMGMMPHPEAFL
CEEEEEEEEEEEEEEECCCCCCCCCEEECCCCCCCHHHHEEEECCCCCEEEECCCCHHHH
HRTNHPRWTREDLPEEGDGLVLFRNAADYAKANLL
CCCCCCCCCHHCCCCCCCCEEEECCCCCCHHHCCC
>Mature Secondary Structure 
AKARAIVITGNGTNCEMEAAHACRLGGFDETVIAHISDILTGEIRLDDFHFLNLTGGFL
CCCEEEEEECCCCCCEEHHHHEEECCCCCHHHHHHHHHHHCCEEEECCEEEEEEECCCC
DGDDLGSAKAQANRFRYARVDDLEEHLIDQIIRFIDAGKLILGVCNGFQLMTKMGLLPAV
CCCCCCCCHHHHHHEEEECCCHHHHHHHHHHHHHHCCCCEEEEHHCCHHHHHHHCCCCCC
DGAYLAQTATLTFNACGRFQDRWVYLKVDQASPSIYTKGVETGLYLPIRHGEGKFVVDSP
CCHHEEEEEEEEEECCCCCCCCEEEEEEECCCCCEEECCCCCCEEEEEEECCCCEEEECC
ATLAAIEAKHLAVFTYSDETYSAPTMEFPLNPNGSVNAIAAVCNESGRLMGMMPHPEAFL
CEEEEEEEEEEEEEEECCCCCCCCCEEECCCCCCCHHHHEEEECCCCCEEEECCCCHHHH
HRTNHPRWTREDLPEEGDGLVLFRNAADYAKANLL
CCCCCCCCCHHCCCCCCCCEEEECCCCCCHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA