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The map label for this gene is dspA [H]

Identifier: 39996730

GI number: 39996730

Start: 1785617

End: 1787749

Strand: Direct

Name: dspA [H]

Synonym: GSU1630

Alternate gene names: 39996730

Gene position: 1785617-1787749 (Clockwise)

Preceding gene: 39996726

Following gene: 39996731

Centisome position: 46.82

GC content: 52.74

Gene sequence:

>2133_bases
TTGTGCTACTATAAGCCCGTCAAGAACGAGCGCTTTCTCCGTCCTTGTTCATACGGTTCCATGAAAAATACCCTTGAAAA
GCGAATAATCCTTTTTTCATTCATCATTCTGTTTCTCACGATTGCCGCCAATTCCGGCATGGATATCGTGGGGTTCAGGC
GTGATTATATTCAGGCGCTGATCCTGCGATCGCAAAGCCTCGGAACCTCCTTGCGCGGGAGTATCGAGAAGGTTGTCGGG
CTCGGCATCGACATCAGGGACATCGAAGGCCTCAGTGAAAAATGTCGGGATTTGGTCAATTCCAGCCCCGAAATTGCCTA
TTGCGTCATTACAGACAGCGAAAGTTCAGTTCTGTTTCTCAACGATCCCGTCTATCGCTCCCTACGCTTCGACATCATCA
AGAAGGCTTTTACCACCCGACTCGACCAGAGTATCCACCTGATCGGGGAGGATGGAGCCTATTACGATACGGTGACGCCG
GTCCGTTCATCGGATGGCAAGCAGGTGGCGCTCATCCACATCGGTTTCTCGCAAAAGGTGGTGGATCAGAAGGTTGAGGG
GATCATCCTCCGTTCCGTGATGGTGCTCGGGCTCTTTTTTCTGATCTCTTTCTCGCTGGTGGTTATTTTCGTCAAGAAAA
GCATTGTTCAACCCATTTCCGCCCTGTTGGGCGGGGTGAAAAAGATCACGGAGGGGAACTTCGACCACCGGATCGACGAG
CTGTCCGTATATGAGTTCAACGAGCTGGCCCGGAATGTGAACGTCATGTCAGAGGCCCTGGGAAACCGCGAGGAGGAGAT
CAAGCGCAATTACCAGGAGCTTGAAAATATCCACAATGATCTCCATTCGTCATACCTCAAGCTGGAAAGCCTGAGTCTCG
AACTGGAGAAGAGCGAAGAGCTGTACAAATCTCTGCTGGAAGACGCCAGTGATGCCATCGTTGTCGTTGACGAGAACGAG
ATCGTCAAAATGGTGAATAAGATGGCGGAGGAGTTTTTTGGCCACAGCTCAGAGGAGGTCGTCGGTCTGCCTCTGAGCAG
GATGCTTGTCCTGGTCAAAACCCACAATATCCCCATTGTTTACAATTTTTTCCAAGAGGTGGGGAAGGGGAGACATGTGG
CGGAGGAGATCCGCTTCTCGCGAGTGGAAGGTGAACAGGTTGTGGGACTTATTCACGCCAACACCGTTACCATTGGGTCC
GAGCGCCTCATTCAAGCCATCATCCGCGATGTAACCCGTGAACGGGAGATTCTTTTCAACCTGGAAAAAAGCGCCACTGA
CCTGGCCCGCCTCAACAAGATGAAGGACTCATTCCTGGGGATAGCCTCCCACGAGCTCAAAACGCCACTTACCGTGATCA
TGGGGTATGCGGAGCTGATCCTTTCCGATATGAGTGGCAAGGTCGACCGGAATGTGATCGACATGGTGCAGAACATCTCC
AATGCTGCTGCCCGGCTCGACAATATCGTCAAGGATATGGTCGACATTTCGATGATCGACGAAAGACGGCTCCGGCTCAA
GCTCGACGATGTCGATGTGAACCGGCTGGTCGAAGACTCCATGAACGAGCTCCGCTTTTTCGTCTCAATGCGCAAGCAGA
AGCTGGTCGGCGAACTGGATGAAACGGTCCCCCGGATCAAGGGAGACCCTGTGCGACTCATGCAGCTCATGTCTAACGTC
ATCGGCAACGCCATCAAGTTTACCCCCGATGGCGGCCGAATCACTGTTTCCACCCGGACCAAGTACCTGCTTCGCTCCAA
GCAGGCGCCGATTCCGGAGCTGGTCAAGCCGGTGGTCAATATCGGCAAGGAACAGCACCTTTACGTTGAAATCACTATCA
CAGACACCGGCATCGGCATCGATATGGATGACCAGCTCCGGATATTCGACAAATTCTACGAGGTGGGAAACATTGAAGAG
CACAGTTCGGGCAAGGTGGCATTCAAGGCGCGCGGCGCGGGTCTGGGACTTTCCATTGCCAAGGGGATAGTCGAGATGCA
CGGCGGCGAGATATGGGTCGAGTCACCTGGCTACAACCCCGAGCAATTTCCCGGCTCAACTTTTCACATTGTGCTGCCTC
TGAATCCCATCACCGGAGATGGAAGTATTGATTACCTCAATCTGCTTGAGTGA

Upstream 100 bases:

>100_bases
TGCGGGCCGAGCGTCAACCGTTTTGTGCCGTCAGAGCCGTTCTCTCGCTGCATCGGGCGAGACAGCCTCATGTATAAAAA
AGATGAGAAGGTTATGAAAG

Downstream 100 bases:

>100_bases
CCTTCGCGACTCTGACCGGAGCCGGTATCCGGCAGCCGTTGATCGTTAAAAAAATTTTCCGCCTTTCGCCTTGAATCATT
CCCCCTGTTTCCTGTATATA

Product: sensory box histidine kinase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 710; Mature: 710

Protein sequence:

>710_residues
MCYYKPVKNERFLRPCSYGSMKNTLEKRIILFSFIILFLTIAANSGMDIVGFRRDYIQALILRSQSLGTSLRGSIEKVVG
LGIDIRDIEGLSEKCRDLVNSSPEIAYCVITDSESSVLFLNDPVYRSLRFDIIKKAFTTRLDQSIHLIGEDGAYYDTVTP
VRSSDGKQVALIHIGFSQKVVDQKVEGIILRSVMVLGLFFLISFSLVVIFVKKSIVQPISALLGGVKKITEGNFDHRIDE
LSVYEFNELARNVNVMSEALGNREEEIKRNYQELENIHNDLHSSYLKLESLSLELEKSEELYKSLLEDASDAIVVVDENE
IVKMVNKMAEEFFGHSSEEVVGLPLSRMLVLVKTHNIPIVYNFFQEVGKGRHVAEEIRFSRVEGEQVVGLIHANTVTIGS
ERLIQAIIRDVTREREILFNLEKSATDLARLNKMKDSFLGIASHELKTPLTVIMGYAELILSDMSGKVDRNVIDMVQNIS
NAAARLDNIVKDMVDISMIDERRLRLKLDDVDVNRLVEDSMNELRFFVSMRKQKLVGELDETVPRIKGDPVRLMQLMSNV
IGNAIKFTPDGGRITVSTRTKYLLRSKQAPIPELVKPVVNIGKEQHLYVEITITDTGIGIDMDDQLRIFDKFYEVGNIEE
HSSGKVAFKARGAGLGLSIAKGIVEMHGGEIWVESPGYNPEQFPGSTFHIVLPLNPITGDGSIDYLNLLE

Sequences:

>Translated_710_residues
MCYYKPVKNERFLRPCSYGSMKNTLEKRIILFSFIILFLTIAANSGMDIVGFRRDYIQALILRSQSLGTSLRGSIEKVVG
LGIDIRDIEGLSEKCRDLVNSSPEIAYCVITDSESSVLFLNDPVYRSLRFDIIKKAFTTRLDQSIHLIGEDGAYYDTVTP
VRSSDGKQVALIHIGFSQKVVDQKVEGIILRSVMVLGLFFLISFSLVVIFVKKSIVQPISALLGGVKKITEGNFDHRIDE
LSVYEFNELARNVNVMSEALGNREEEIKRNYQELENIHNDLHSSYLKLESLSLELEKSEELYKSLLEDASDAIVVVDENE
IVKMVNKMAEEFFGHSSEEVVGLPLSRMLVLVKTHNIPIVYNFFQEVGKGRHVAEEIRFSRVEGEQVVGLIHANTVTIGS
ERLIQAIIRDVTREREILFNLEKSATDLARLNKMKDSFLGIASHELKTPLTVIMGYAELILSDMSGKVDRNVIDMVQNIS
NAAARLDNIVKDMVDISMIDERRLRLKLDDVDVNRLVEDSMNELRFFVSMRKQKLVGELDETVPRIKGDPVRLMQLMSNV
IGNAIKFTPDGGRITVSTRTKYLLRSKQAPIPELVKPVVNIGKEQHLYVEITITDTGIGIDMDDQLRIFDKFYEVGNIEE
HSSGKVAFKARGAGLGLSIAKGIVEMHGGEIWVESPGYNPEQFPGSTFHIVLPLNPITGDGSIDYLNLLE
>Mature_710_residues
MCYYKPVKNERFLRPCSYGSMKNTLEKRIILFSFIILFLTIAANSGMDIVGFRRDYIQALILRSQSLGTSLRGSIEKVVG
LGIDIRDIEGLSEKCRDLVNSSPEIAYCVITDSESSVLFLNDPVYRSLRFDIIKKAFTTRLDQSIHLIGEDGAYYDTVTP
VRSSDGKQVALIHIGFSQKVVDQKVEGIILRSVMVLGLFFLISFSLVVIFVKKSIVQPISALLGGVKKITEGNFDHRIDE
LSVYEFNELARNVNVMSEALGNREEEIKRNYQELENIHNDLHSSYLKLESLSLELEKSEELYKSLLEDASDAIVVVDENE
IVKMVNKMAEEFFGHSSEEVVGLPLSRMLVLVKTHNIPIVYNFFQEVGKGRHVAEEIRFSRVEGEQVVGLIHANTVTIGS
ERLIQAIIRDVTREREILFNLEKSATDLARLNKMKDSFLGIASHELKTPLTVIMGYAELILSDMSGKVDRNVIDMVQNIS
NAAARLDNIVKDMVDISMIDERRLRLKLDDVDVNRLVEDSMNELRFFVSMRKQKLVGELDETVPRIKGDPVRLMQLMSNV
IGNAIKFTPDGGRITVSTRTKYLLRSKQAPIPELVKPVVNIGKEQHLYVEITITDTGIGIDMDDQLRIFDKFYEVGNIEE
HSSGKVAFKARGAGLGLSIAKGIVEMHGGEIWVESPGYNPEQFPGSTFHIVLPLNPITGDGSIDYLNLLE

Specific function: Member Of The Two-Component Regulatory System Atos/Atoc; May Activate Atoc By Phosphorylation. [C]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PAS (PER-ARNT-SIM) domain [H]

Homologues:

Organism=Escherichia coli, GI1788549, Length=453, Percent_Identity=24.9448123620309, Blast_Score=115, Evalue=1e-26,
Organism=Escherichia coli, GI48994928, Length=461, Percent_Identity=25.3796095444685, Blast_Score=112, Evalue=9e-26,
Organism=Escherichia coli, GI145693157, Length=300, Percent_Identity=30, Blast_Score=105, Evalue=8e-24,
Organism=Escherichia coli, GI1789149, Length=276, Percent_Identity=29.7101449275362, Blast_Score=100, Evalue=3e-22,
Organism=Escherichia coli, GI1788713, Length=295, Percent_Identity=26.4406779661017, Blast_Score=97, Evalue=4e-21,
Organism=Escherichia coli, GI1788393, Length=271, Percent_Identity=28.7822878228782, Blast_Score=91, Evalue=4e-19,
Organism=Escherichia coli, GI1790436, Length=287, Percent_Identity=27.5261324041812, Blast_Score=90, Evalue=5e-19,
Organism=Escherichia coli, GI87081816, Length=288, Percent_Identity=27.4305555555556, Blast_Score=89, Evalue=1e-18,
Organism=Escherichia coli, GI1786600, Length=405, Percent_Identity=24.6913580246914, Blast_Score=88, Evalue=2e-18,
Organism=Escherichia coli, GI1790300, Length=392, Percent_Identity=25.2551020408163, Blast_Score=84, Evalue=3e-17,
Organism=Escherichia coli, GI1788279, Length=246, Percent_Identity=25.609756097561, Blast_Score=78, Evalue=2e-15,
Organism=Escherichia coli, GI1786783, Length=271, Percent_Identity=26.5682656826568, Blast_Score=72, Evalue=8e-14,
Organism=Escherichia coli, GI1790861, Length=229, Percent_Identity=26.6375545851528, Blast_Score=69, Evalue=1e-12,
Organism=Escherichia coli, GI1786912, Length=287, Percent_Identity=25.0871080139373, Blast_Score=67, Evalue=3e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR003660
- InterPro:   IPR000014
- InterPro:   IPR013767
- InterPro:   IPR004358
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR009082 [H]

Pfam domain/function: PF00672 HAMP; PF02518 HATPase_c; PF00512 HisKA; PF00989 PAS [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 79889; Mature: 79889

Theoretical pI: Translated: 5.41; Mature: 5.41

Prosite motif: PS50885 HAMP ; PS50112 PAS ; PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MCYYKPVKNERFLRPCSYGSMKNTLEKRIILFSFIILFLTIAANSGMDIVGFRRDYIQAL
CCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEHHHHHHHHHH
ILRSQSLGTSLRGSIEKVVGLGIDIRDIEGLSEKCRDLVNSSPEIAYCVITDSESSVLFL
HHHHHHCCCHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHCCCCCEEEEEEECCCCCEEEE
NDPVYRSLRFDIIKKAFTTRLDQSIHLIGEDGAYYDTVTPVRSSDGKQVALIHIGFSQKV
CCHHHHHHHHHHHHHHHHHHHCCCEEEEECCCCEECCCCCCCCCCCCEEEEEEECCHHHH
VDQKVEGIILRSVMVLGLFFLISFSLVVIFVKKSIVQPISALLGGVKKITEGNFDHRIDE
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCC
LSVYEFNELARNVNVMSEALGNREEEIKRNYQELENIHNDLHSSYLKLESLSLELEKSEE
CHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEHHHHHH
LYKSLLEDASDAIVVVDENEIVKMVNKMAEEFFGHSSEEVVGLPLSRMLVLVKTHNIPIV
HHHHHHHCCCCEEEEECCHHHHHHHHHHHHHHCCCCCCCEECCCHHHHEEEEEECCCCEE
YNFFQEVGKGRHVAEEIRFSRVEGEQVVGLIHANTVTIGSERLIQAIIRDVTREREILFN
EHHHHHHCCCCHHHHHHHHHHCCCCCEEEEEEECEEEECHHHHHHHHHHHHHHHHHHHHC
LEKSATDLARLNKMKDSFLGIASHELKTPLTVIMGYAELILSDMSGKVDRNVIDMVQNIS
CHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHH
NAAARLDNIVKDMVDISMIDERRLRLKLDDVDVNRLVEDSMNELRFFVSMRKQKLVGELD
HHHHHHHHHHHHHHHHHHHCCCEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ETVPRIKGDPVRLMQLMSNVIGNAIKFTPDGGRITVSTRTKYLLRSKQAPIPELVKPVVN
HHHCCCCCCHHHHHHHHHHHHCCCEEECCCCCEEEEECHHHHHHHCCCCCCHHHHHHHHH
IGKEQHLYVEITITDTGIGIDMDDQLRIFDKFYEVGNIEEHSSGKVAFKARGAGLGLSIA
CCCCCEEEEEEEEEECCCCCCCCCHHHHHHHHHHCCCCCCCCCCCEEEEECCCCCCHHHH
KGIVEMHGGEIWVESPGYNPEQFPGSTFHIVLPLNPITGDGSIDYLNLLE
HHHHHHCCCEEEEECCCCCCCCCCCCEEEEEEECCCCCCCCCCCHHCCCC
>Mature Secondary Structure
MCYYKPVKNERFLRPCSYGSMKNTLEKRIILFSFIILFLTIAANSGMDIVGFRRDYIQAL
CCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEHHHHHHHHHH
ILRSQSLGTSLRGSIEKVVGLGIDIRDIEGLSEKCRDLVNSSPEIAYCVITDSESSVLFL
HHHHHHCCCHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHCCCCCEEEEEEECCCCCEEEE
NDPVYRSLRFDIIKKAFTTRLDQSIHLIGEDGAYYDTVTPVRSSDGKQVALIHIGFSQKV
CCHHHHHHHHHHHHHHHHHHHCCCEEEEECCCCEECCCCCCCCCCCCEEEEEEECCHHHH
VDQKVEGIILRSVMVLGLFFLISFSLVVIFVKKSIVQPISALLGGVKKITEGNFDHRIDE
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCC
LSVYEFNELARNVNVMSEALGNREEEIKRNYQELENIHNDLHSSYLKLESLSLELEKSEE
CHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEHHHHHH
LYKSLLEDASDAIVVVDENEIVKMVNKMAEEFFGHSSEEVVGLPLSRMLVLVKTHNIPIV
HHHHHHHCCCCEEEEECCHHHHHHHHHHHHHHCCCCCCCEECCCHHHHEEEEEECCCCEE
YNFFQEVGKGRHVAEEIRFSRVEGEQVVGLIHANTVTIGSERLIQAIIRDVTREREILFN
EHHHHHHCCCCHHHHHHHHHHCCCCCEEEEEEECEEEECHHHHHHHHHHHHHHHHHHHHC
LEKSATDLARLNKMKDSFLGIASHELKTPLTVIMGYAELILSDMSGKVDRNVIDMVQNIS
CHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHH
NAAARLDNIVKDMVDISMIDERRLRLKLDDVDVNRLVEDSMNELRFFVSMRKQKLVGELD
HHHHHHHHHHHHHHHHHHHCCCEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ETVPRIKGDPVRLMQLMSNVIGNAIKFTPDGGRITVSTRTKYLLRSKQAPIPELVKPVVN
HHHCCCCCCHHHHHHHHHHHHCCCEEECCCCCEEEEECHHHHHHHCCCCCCHHHHHHHHH
IGKEQHLYVEITITDTGIGIDMDDQLRIFDKFYEVGNIEEHSSGKVAFKARGAGLGLSIA
CCCCCEEEEEEEEEECCCCCCCCCHHHHHHHHHHCCCCCCCCCCCEEEEECCCCCCHHHH
KGIVEMHGGEIWVESPGYNPEQFPGSTFHIVLPLNPITGDGSIDYLNLLE
HHHHHHCCCEEEEECCCCCCCCCCCCEEEEEEECCCCCCCCCCCHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8535519; 8905231; 3141423 [H]