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The map label for this gene is fabD [H]

Identifier: 39996702

GI number: 39996702

Start: 1753957

End: 1754880

Strand: Direct

Name: fabD [H]

Synonym: GSU1602

Alternate gene names: 39996702

Gene position: 1753957-1754880 (Clockwise)

Preceding gene: 39996701

Following gene: 39996703

Centisome position: 45.99

GC content: 61.69

Gene sequence:

>924_bases
ATGAGCAAGCGAGCTTTCATATTCCCCGGCCAAGGGTCCCAGTATGCCGGAATGGGCAAGGATCTGGCCGATACCTTTCC
GGTTGCCCGTCAGGTCTTCGAGGAAGCTGATGATGCCCTCGGCAGCTCCCTTTCCCGACTCTGCTTTGAAGGTCCCGAAG
AGCAGTTGAAGCTCACCGCCAATACTCAGCCCGCCATCCTGACCACAAGTGTTGCCGCATTCAGGGTGCTTCAGGCTGAA
ACGGGACTCACCGCAGACTTCCTGGCAGGACACTCTCTCGGCGAGTACTCGGCGCTTGTGGCTGCCGGAGCACTTGGCTT
TGCGGATGCTGTCCGGACGGTTCGAGCCCGCGGCACCTTCATGCAGGAGGCTGTGCCGGTTGGAGAGGGGGCAATGGCCG
CGATGCTCGGAATCGAACCGGCTGTCCTTGCCGAAATATGCGCCGAAGCGGCCCAGGGTGAGGTCGTTTCTCCCGCAAAC
TTCAATTCGCCCGGCCAGATCGTCATTGCCGGAAACACCGGTGCGGTCAACCGTGCCATCGAGATTGCCAAGGCAAAGGG
GTTCCGCAAGGCGATGCTCCTGCCGGTGAGCGCTCCCTTCCATTCGAGCCTCATGGTGCCTGCCGGTGAACGGCTTGCCG
AGGTTCTGGCAGCGGTTGCGGTCGGCGATCTGGTCGCTCCCGTGGTGACCAACGTGGAGGCAACGCCCAACTCCGACAAG
GGAAGGGTAAAAGAACTCCTGGTCAGACAGGTAAGCGCTCCGGTGCTCTGGGATGCCTCGGTGAGGGAAATGGTTTCGCT
CGGCGTCACCCGGTTTGTGGAGATCGGGCCGGGCAAAGTTCTGTCGGGGCTGGTCAAGCGGATCGAGAAGGAAGCGGGTA
CCGCCAACGTCGAGGATACGGCCGGTATCAGGGGCCTCGCCTAA

Upstream 100 bases:

>100_bases
ATCAAGCCCAACGATGTAGTGGTATTCGATGCCTTCGGCGGCGGGCTTACCTGGGGATCGGCACTGGTGCGCTGGTAACG
GACCAAGCAAGGAGCTATCA

Downstream 100 bases:

>100_bases
GGAGACGGGAATGAGTCTTGCTGGAAAAATCGCAGTGGTTACAGGAGCTTCTCGTGGCATCGGCAGGGAGATCGCCCTCC
GGCTCGCCCGTGAGGGCGCT

Product: malonyl CoA-ACP transacylase

Products: NA

Alternate protein names: MCT [H]

Number of amino acids: Translated: 307; Mature: 306

Protein sequence:

>307_residues
MSKRAFIFPGQGSQYAGMGKDLADTFPVARQVFEEADDALGSSLSRLCFEGPEEQLKLTANTQPAILTTSVAAFRVLQAE
TGLTADFLAGHSLGEYSALVAAGALGFADAVRTVRARGTFMQEAVPVGEGAMAAMLGIEPAVLAEICAEAAQGEVVSPAN
FNSPGQIVIAGNTGAVNRAIEIAKAKGFRKAMLLPVSAPFHSSLMVPAGERLAEVLAAVAVGDLVAPVVTNVEATPNSDK
GRVKELLVRQVSAPVLWDASVREMVSLGVTRFVEIGPGKVLSGLVKRIEKEAGTANVEDTAGIRGLA

Sequences:

>Translated_307_residues
MSKRAFIFPGQGSQYAGMGKDLADTFPVARQVFEEADDALGSSLSRLCFEGPEEQLKLTANTQPAILTTSVAAFRVLQAE
TGLTADFLAGHSLGEYSALVAAGALGFADAVRTVRARGTFMQEAVPVGEGAMAAMLGIEPAVLAEICAEAAQGEVVSPAN
FNSPGQIVIAGNTGAVNRAIEIAKAKGFRKAMLLPVSAPFHSSLMVPAGERLAEVLAAVAVGDLVAPVVTNVEATPNSDK
GRVKELLVRQVSAPVLWDASVREMVSLGVTRFVEIGPGKVLSGLVKRIEKEAGTANVEDTAGIRGLA
>Mature_306_residues
SKRAFIFPGQGSQYAGMGKDLADTFPVARQVFEEADDALGSSLSRLCFEGPEEQLKLTANTQPAILTTSVAAFRVLQAET
GLTADFLAGHSLGEYSALVAAGALGFADAVRTVRARGTFMQEAVPVGEGAMAAMLGIEPAVLAEICAEAAQGEVVSPANF
NSPGQIVIAGNTGAVNRAIEIAKAKGFRKAMLLPVSAPFHSSLMVPAGERLAEVLAAVAVGDLVAPVVTNVEATPNSDKG
RVKELLVRQVSAPVLWDASVREMVSLGVTRFVEIGPGKVLSGLVKRIEKEAGTANVEDTAGIRGLA

Specific function: Fatty acid biosynthesis. [C]

COG id: COG0331

COG function: function code I; (acyl-carrier-protein) S-malonyltransferase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the fabD family [H]

Homologues:

Organism=Homo sapiens, GI51243059, Length=302, Percent_Identity=33.112582781457, Blast_Score=149, Evalue=2e-36,
Organism=Homo sapiens, GI27477045, Length=107, Percent_Identity=42.0560747663551, Blast_Score=75, Evalue=7e-14,
Organism=Escherichia coli, GI1787334, Length=288, Percent_Identity=52.4305555555556, Blast_Score=281, Evalue=4e-77,
Organism=Caenorhabditis elegans, GI71984332, Length=293, Percent_Identity=33.4470989761092, Blast_Score=144, Evalue=8e-35,
Organism=Caenorhabditis elegans, GI17550940, Length=295, Percent_Identity=29.8305084745763, Blast_Score=101, Evalue=5e-22,
Organism=Drosophila melanogaster, GI24665753, Length=300, Percent_Identity=38.6666666666667, Blast_Score=167, Evalue=7e-42,

Paralogues:

None

Copy number: 500 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001227
- InterPro:   IPR014043
- InterPro:   IPR016035
- InterPro:   IPR004410
- InterPro:   IPR016036 [H]

Pfam domain/function: PF00698 Acyl_transf_1 [H]

EC number: =2.3.1.39 [H]

Molecular weight: Translated: 31788; Mature: 31657

Theoretical pI: Translated: 4.91; Mature: 4.91

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSKRAFIFPGQGSQYAGMGKDLADTFPVARQVFEEADDALGSSLSRLCFEGPEEQLKLTA
CCCCEEEECCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHEEEEC
NTQPAILTTSVAAFRVLQAETGLTADFLAGHSLGEYSALVAAGALGFADAVRTVRARGTF
CCCCCEEHHHHHHHHHHHHCCCCCHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
MQEAVPVGEGAMAAMLGIEPAVLAEICAEAAQGEVVSPANFNSPGQIVIAGNTGAVNRAI
HHHHCCCCCCHHHHHHCCCHHHHHHHHHHHHCCCEECCCCCCCCCEEEEECCCCCHHHHH
EIAKAKGFRKAMLLPVSAPFHSSLMVPAGERLAEVLAAVAVGDLVAPVVTNVEATPNSDK
HHHHHCCCHHEEEEEECCCCCCCEECCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCH
GRVKELLVRQVSAPVLWDASVREMVSLGVTRFVEIGPGKVLSGLVKRIEKEAGTANVEDT
HHHHHHHHHHHCCCCEECHHHHHHHHHHHHHHEECCCCHHHHHHHHHHHHHCCCCCCCCC
AGIRGLA
CCCCCCC
>Mature Secondary Structure 
SKRAFIFPGQGSQYAGMGKDLADTFPVARQVFEEADDALGSSLSRLCFEGPEEQLKLTA
CCCEEEECCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHEEEEC
NTQPAILTTSVAAFRVLQAETGLTADFLAGHSLGEYSALVAAGALGFADAVRTVRARGTF
CCCCCEEHHHHHHHHHHHHCCCCCHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
MQEAVPVGEGAMAAMLGIEPAVLAEICAEAAQGEVVSPANFNSPGQIVIAGNTGAVNRAI
HHHHCCCCCCHHHHHHCCCHHHHHHHHHHHHCCCEECCCCCCCCCEEEEECCCCCHHHHH
EIAKAKGFRKAMLLPVSAPFHSSLMVPAGERLAEVLAAVAVGDLVAPVVTNVEATPNSDK
HHHHHCCCHHEEEEEECCCCCCCEECCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCH
GRVKELLVRQVSAPVLWDASVREMVSLGVTRFVEIGPGKVLSGLVKRIEKEAGTANVEDT
HHHHHHHHHHHCCCCEECHHHHHHHHHHHHHHEECCCCHHHHHHHHHHHHHCCCCCCCCC
AGIRGLA
CCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8759840; 9534248; 9384377 [H]