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The map label for this gene is fabH-2 [H]

Identifier: 39996701

GI number: 39996701

Start: 1752957

End: 1753934

Strand: Direct

Name: fabH-2 [H]

Synonym: GSU1601

Alternate gene names: 39996701

Gene position: 1752957-1753934 (Clockwise)

Preceding gene: 39996700

Following gene: 39996702

Centisome position: 45.96

GC content: 57.77

Gene sequence:

>978_bases
ATGAGAGCAAGGATCGTCGGGACCGGTTCGGCCGTCCCTTCCAAGGTGCTTACCAATTTCGATCTGGAGAAGATGGTCGA
TACCTCCGACGAGTGGGTAACCACGCGCACCGGAATCAAAGAGCGCCGCATTGCCGTTGATGGGGAATATACTTCTACCT
TTGCGACACTGGCAGCGGAACGGGCCCTCGAAATGGCCGGCGTCAAGGCTTCGGATCTCGATCTGTTGATTGTCGCAACT
ATTACGCCTGATTTTCCGTTTCCCGCCACCGCATGTGTGGTCCAGAGCAATCTCAAGGCAACGAAGGCGGCTGCCTATGA
TATCTCGGCAGCTTGCTCAGGCTTTATCTACGCCCTTGCTCAAGCATCTAATGCAATCAGATCGGGATCCGCCCGGAAGG
CTCTGGTCATTGGTGCGGAAGTTCTGTCGCGGATTATCGACTGGACAGACCGCAACACCTGCCTTCTTTTCGGCGACGGC
GCCGGCGCGGTGGTTCTGGAGGCATGCGATGACGGCCATGGGGTCCTGTCCACCCACCTTCACAGTGACGGCTCGTACTG
GGAACTGCTCTATCAACCCGGTTGCGGCAACAGAAATCCCGCCGTCCAGAAGACTCTTGACGACCGTCGTATCTATCTCA
TGATGCAGGGGAATGAGGTTTTCAAACTCGCCGTGAGGGCCATGGAGGATGCCGCCCTTGAAGCCCTTGATGCAAACGGG
CTCACGCCTGCAGACATTTCGTTGTTCATCCCCCATCAGGCCAATCGCCGCATCATTGATGCCATCGGCAAACGCCTCGG
CTTGCCGGGCGAAAAGGTCTACGTCAATCTCGACCGGTTCGGCAATACCTCGGCGGCATCCATTCCGCTGGCACTGGACG
AAGCTAACCGCTCGGGCCGGATCAAGCCCAACGATGTAGTGGTATTCGATGCCTTCGGCGGCGGGCTTACCTGGGGATCG
GCACTGGTGCGCTGGTAA

Upstream 100 bases:

>100_bases
CCAACGGCTTGCCGAGAAGATGGAAACCGAGTTCACGGCTTACATGCAGCAGTTTGATGCTGTGAAGGAAGCTGTCGCAG
GTTAGAAAGGTCACGGGATG

Downstream 100 bases:

>100_bases
CGGACCAAGCAAGGAGCTATCAATGAGCAAGCGAGCTTTCATATTCCCCGGCCAAGGGTCCCAGTATGCCGGAATGGGCA
AGGATCTGGCCGATACCTTT

Product: 3-oxoacyl-ACP synthase

Products: NA

Alternate protein names: 3-oxoacyl-[acyl-carrier-protein] synthase III; Beta-ketoacyl-ACP synthase III; KAS III [H]

Number of amino acids: Translated: 325; Mature: 325

Protein sequence:

>325_residues
MRARIVGTGSAVPSKVLTNFDLEKMVDTSDEWVTTRTGIKERRIAVDGEYTSTFATLAAERALEMAGVKASDLDLLIVAT
ITPDFPFPATACVVQSNLKATKAAAYDISAACSGFIYALAQASNAIRSGSARKALVIGAEVLSRIIDWTDRNTCLLFGDG
AGAVVLEACDDGHGVLSTHLHSDGSYWELLYQPGCGNRNPAVQKTLDDRRIYLMMQGNEVFKLAVRAMEDAALEALDANG
LTPADISLFIPHQANRRIIDAIGKRLGLPGEKVYVNLDRFGNTSAASIPLALDEANRSGRIKPNDVVVFDAFGGGLTWGS
ALVRW

Sequences:

>Translated_325_residues
MRARIVGTGSAVPSKVLTNFDLEKMVDTSDEWVTTRTGIKERRIAVDGEYTSTFATLAAERALEMAGVKASDLDLLIVAT
ITPDFPFPATACVVQSNLKATKAAAYDISAACSGFIYALAQASNAIRSGSARKALVIGAEVLSRIIDWTDRNTCLLFGDG
AGAVVLEACDDGHGVLSTHLHSDGSYWELLYQPGCGNRNPAVQKTLDDRRIYLMMQGNEVFKLAVRAMEDAALEALDANG
LTPADISLFIPHQANRRIIDAIGKRLGLPGEKVYVNLDRFGNTSAASIPLALDEANRSGRIKPNDVVVFDAFGGGLTWGS
ALVRW
>Mature_325_residues
MRARIVGTGSAVPSKVLTNFDLEKMVDTSDEWVTTRTGIKERRIAVDGEYTSTFATLAAERALEMAGVKASDLDLLIVAT
ITPDFPFPATACVVQSNLKATKAAAYDISAACSGFIYALAQASNAIRSGSARKALVIGAEVLSRIIDWTDRNTCLLFGDG
AGAVVLEACDDGHGVLSTHLHSDGSYWELLYQPGCGNRNPAVQKTLDDRRIYLMMQGNEVFKLAVRAMEDAALEALDANG
LTPADISLFIPHQANRRIIDAIGKRLGLPGEKVYVNLDRFGNTSAASIPLALDEANRSGRIKPNDVVVFDAFGGGLTWGS
ALVRW

Specific function: Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the

COG id: COG0332

COG function: function code I; 3-oxoacyl-[acyl-carrier-protein] synthase III

Gene ontology:

Cell location: Cytoplasm (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the fabH family [H]

Homologues:

Organism=Escherichia coli, GI1787333, Length=325, Percent_Identity=52.3076923076923, Blast_Score=333, Evalue=7e-93,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013751
- InterPro:   IPR013747
- InterPro:   IPR004655
- InterPro:   IPR016039
- InterPro:   IPR016038 [H]

Pfam domain/function: PF08545 ACP_syn_III; PF08541 ACP_syn_III_C [H]

EC number: =2.3.1.180 [H]

Molecular weight: Translated: 34852; Mature: 34852

Theoretical pI: Translated: 5.43; Mature: 5.43

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRARIVGTGSAVPSKVLTNFDLEKMVDTSDEWVTTRTGIKERRIAVDGEYTSTFATLAAE
CCEEEEECCCCCCHHHHHCCCHHHHHCCCCCEEEECCCCCCCEEEECCCHHHHHHHHHHH
RALEMAGVKASDLDLLIVATITPDFPFPATACVVQSNLKATKAAAYDISAACSGFIYALA
HHHHHCCCCCCCCCEEEEEEECCCCCCCCHHEEECCCCCHHHHHHHHHHHHHHHHHHHHH
QASNAIRSGSARKALVIGAEVLSRIIDWTDRNTCLLFGDGAGAVVLEACDDGHGVLSTHL
HHHHHHHCCCCCEEEEEEHHHHHHHHCCCCCCEEEEEECCCCEEEEEECCCCCCEEEEEE
HSDGSYWELLYQPGCGNRNPAVQKTLDDRRIYLMMQGNEVFKLAVRAMEDAALEALDANG
CCCCCEEEEEECCCCCCCCCHHHHCCCCCEEEEEEECCHHHHHHHHHHHHHHHHHHCCCC
LTPADISLFIPHQANRRIIDAIGKRLGLPGEKVYVNLDRFGNTSAASIPLALDEANRSGR
CCCCCEEEEECCCCCCHHHHHHHHHHCCCCCEEEEEEECCCCCCCCEEEEEEECCCCCCC
IKPNDVVVFDAFGGGLTWGSALVRW
CCCCCEEEEECCCCCCCHHHHHHCC
>Mature Secondary Structure
MRARIVGTGSAVPSKVLTNFDLEKMVDTSDEWVTTRTGIKERRIAVDGEYTSTFATLAAE
CCEEEEECCCCCCHHHHHCCCHHHHHCCCCCEEEECCCCCCCEEEECCCHHHHHHHHHHH
RALEMAGVKASDLDLLIVATITPDFPFPATACVVQSNLKATKAAAYDISAACSGFIYALA
HHHHHCCCCCCCCCEEEEEEECCCCCCCCHHEEECCCCCHHHHHHHHHHHHHHHHHHHHH
QASNAIRSGSARKALVIGAEVLSRIIDWTDRNTCLLFGDGAGAVVLEACDDGHGVLSTHL
HHHHHHHCCCCCEEEEEEHHHHHHHHCCCCCCEEEEEECCCCEEEEEECCCCCCEEEEEE
HSDGSYWELLYQPGCGNRNPAVQKTLDDRRIYLMMQGNEVFKLAVRAMEDAALEALDANG
CCCCCEEEEEECCCCCCCCCHHHHCCCCCEEEEEEECCHHHHHHHHHHHHHHHHHHCCCC
LTPADISLFIPHQANRRIIDAIGKRLGLPGEKVYVNLDRFGNTSAASIPLALDEANRSGR
CCCCCEEEEECCCCCCHHHHHHHHHHCCCCCEEEEEEECCCCCCCCEEEEEEECCCCCCC
IKPNDVVVFDAFGGGLTWGSALVRW
CCCCCEEEEECCCCCCCHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11997336 [H]