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The map label for this gene is htpX [H]

Identifier: 39996667

GI number: 39996667

Start: 1721015

End: 1721875

Strand: Direct

Name: htpX [H]

Synonym: GSU1567

Alternate gene names: 39996667

Gene position: 1721015-1721875 (Clockwise)

Preceding gene: 39996666

Following gene: 39996668

Centisome position: 45.12

GC content: 61.44

Gene sequence:

>861_bases
ATGAACAGGCTCAAGACAACCCTTCTCCTCTCCCTGCTGACCGTTCTCATGGTCCTCATGGGCAGTGCCCTGGGCGGCAA
GTCCGGTATGATCACGGCTTTTGTCATAGCCCTTGGCATGAACTTCTTCTCCTACTGGTTTTCCGACAAGATCGTCCTCA
AGATGTACGGAGCCCGCGAGGTCGACGAGCACGACCATCCGCAGTTCTACGGCATGGTTCGCCGCCTGGCCCTTCAGGCG
GGGCTCCCCATGCCCAAGGTCTACATCATCCCGTCCGACAGCCCCAACGCCTTTGCCACGGGAAGGAATCCGCAGCATGC
CGCCGTAGCCGCGACAGAAGGCATCTTGCGGATTCTGTCGCCGGATGAACTCGAAGGGGTAATGGCCCATGAACTTGCCC
ACGTCCAGAACCGGGACATCCTGGTGGGAACCATTGCCGCCACCTTCGCCGGTGCAATCTCCATGATCGGCAACATGCTC
CAGTGGGGCGCCATGCTCGGCGTCGGCAGAAACGACGACGAGGAGGGGGGCGCCGGCGGCCTGATGGGTTCGCTGGTCAT
GGCCATTGTCGCACCCATGGCGGCCATGCTGATCCAGATGGCGGTCTCGCGCTCCCGGGAGTACCTGGCGGACGAAACCG
GCGCAAGGATCTGCGGCAGACCACTGGCACTGGCCAATGCCCTGCGCAAACTCCATGTCGCATCTCACAGCATACCCATG
CAGGAGGCCAGACCGGCCTCAGCACACATGTTCATCGTTAATCCACTGACCGGGGGCAGCCTCCTCTCCCTCTTCTCGAC
CCACCCGCCAATGGAGGAGCGGATTGCCCGGCTTGAAGCGATGTCCAGAACATCAAGGTAA

Upstream 100 bases:

>100_bases
GGGCAGATATCTGCCAACAAGACCTTTATCCAGGCATATGCCGGGGGTAAAGGTCTTTTTTATTACCCCCGGCGATAGCA
AATCGTCGGAGGTAATGACA

Downstream 100 bases:

>100_bases
CCAAAGAAAGGAGAACAGCACCATGAAGTGTCCCGTCTGCACCACCGTCAATCTGGTAATGTCTGAACGCCAGGGAATCG
AAATCGATTACTGCCCCGAA

Product: M48 family peptidase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 286; Mature: 286

Protein sequence:

>286_residues
MNRLKTTLLLSLLTVLMVLMGSALGGKSGMITAFVIALGMNFFSYWFSDKIVLKMYGAREVDEHDHPQFYGMVRRLALQA
GLPMPKVYIIPSDSPNAFATGRNPQHAAVAATEGILRILSPDELEGVMAHELAHVQNRDILVGTIAATFAGAISMIGNML
QWGAMLGVGRNDDEEGGAGGLMGSLVMAIVAPMAAMLIQMAVSRSREYLADETGARICGRPLALANALRKLHVASHSIPM
QEARPASAHMFIVNPLTGGSLLSLFSTHPPMEERIARLEAMSRTSR

Sequences:

>Translated_286_residues
MNRLKTTLLLSLLTVLMVLMGSALGGKSGMITAFVIALGMNFFSYWFSDKIVLKMYGAREVDEHDHPQFYGMVRRLALQA
GLPMPKVYIIPSDSPNAFATGRNPQHAAVAATEGILRILSPDELEGVMAHELAHVQNRDILVGTIAATFAGAISMIGNML
QWGAMLGVGRNDDEEGGAGGLMGSLVMAIVAPMAAMLIQMAVSRSREYLADETGARICGRPLALANALRKLHVASHSIPM
QEARPASAHMFIVNPLTGGSLLSLFSTHPPMEERIARLEAMSRTSR
>Mature_286_residues
MNRLKTTLLLSLLTVLMVLMGSALGGKSGMITAFVIALGMNFFSYWFSDKIVLKMYGAREVDEHDHPQFYGMVRRLALQA
GLPMPKVYIIPSDSPNAFATGRNPQHAAVAATEGILRILSPDELEGVMAHELAHVQNRDILVGTIAATFAGAISMIGNML
QWGAMLGVGRNDDEEGGAGGLMGSLVMAIVAPMAAMLIQMAVSRSREYLADETGARICGRPLALANALRKLHVASHSIPM
QEARPASAHMFIVNPLTGGSLLSLFSTHPPMEERIARLEAMSRTSR

Specific function: Unknown Function. Overexpression Of A Truncated Form Of The Htpx Protein Leads To An Increase In The Degradation Of Abnormal Proteins. [C]

COG id: COG0501

COG function: function code O; Zn-dependent protease with chaperone function

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase M48B family [H]

Homologues:

Organism=Escherichia coli, GI1788133, Length=259, Percent_Identity=33.2046332046332, Blast_Score=110, Evalue=1e-25,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR022919
- InterPro:   IPR001915 [H]

Pfam domain/function: PF01435 Peptidase_M48 [H]

EC number: 3.4.24.-

Molecular weight: Translated: 30785; Mature: 30785

Theoretical pI: Translated: 8.49; Mature: 8.49

Prosite motif: PS00142 ZINC_PROTEASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
7.3 %Met     (Translated Protein)
7.7 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
7.3 %Met     (Mature Protein)
7.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNRLKTTLLLSLLTVLMVLMGSALGGKSGMITAFVIALGMNFFSYWFSDKIVLKMYGARE
CCHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCEEEEECCCCC
VDEHDHPQFYGMVRRLALQAGLPMPKVYIIPSDSPNAFATGRNPQHAAVAATEGILRILS
CCCCCCHHHHHHHHHHHHHHCCCCCEEEEEECCCCCCEECCCCCCHHHHHHHHHHHHHCC
PDELEGVMAHELAHVQNRDILVGTIAATFAGAISMIGNMLQWGAMLGVGRNDDEEGGAGG
CHHHHHHHHHHHHHHCCCCEEEHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCH
LMGSLVMAIVAPMAAMLIQMAVSRSREYLADETGARICGRPLALANALRKLHVASHSIPM
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHCCHHHHHHHHHHHHHHHCCCCH
QEARPASAHMFIVNPLTGGSLLSLFSTHPPMEERIARLEAMSRTSR
HHCCCCCCEEEEEECCCCHHHHHHHHCCCCHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MNRLKTTLLLSLLTVLMVLMGSALGGKSGMITAFVIALGMNFFSYWFSDKIVLKMYGARE
CCHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCEEEEECCCCC
VDEHDHPQFYGMVRRLALQAGLPMPKVYIIPSDSPNAFATGRNPQHAAVAATEGILRILS
CCCCCCHHHHHHHHHHHHHHCCCCCEEEEEECCCCCCEECCCCCCHHHHHHHHHHHHHCC
PDELEGVMAHELAHVQNRDILVGTIAATFAGAISMIGNMLQWGAMLGVGRNDDEEGGAGG
CHHHHHHHHHHHHHHCCCCEEEHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCH
LMGSLVMAIVAPMAAMLIQMAVSRSREYLADETGARICGRPLALANALRKLHVASHSIPM
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHCCHHHHHHHHHHHHHHHCCCCH
QEARPASAHMFIVNPLTGGSLLSLFSTHPPMEERIARLEAMSRTSR
HHCCCCCCEEEEEECCCCHHHHHHHHCCCCHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: Zn [C]

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA