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The map label for this gene is surE

Identifier: 39996623

GI number: 39996623

Start: 1669765

End: 1670553

Strand: Direct

Name: surE

Synonym: GSU1523

Alternate gene names: 39996623

Gene position: 1669765-1670553 (Clockwise)

Preceding gene: 39996622

Following gene: 39996624

Centisome position: 43.78

GC content: 59.82

Gene sequence:

>789_bases
ATGAATATTCTCGTTACCAATGATGATGGTGTTCACGCCCCGGGAATTGTGGCTCTGGCCGAGGCCCTCAGACTCGTGGG
CACAGTTACCGTGGTAGCTCCCGACCGTGAGCGAAGCGCGGTGGGCCATGCCCTTACGCTCCATCACCCACTCAGGGTTA
CGGAGATCATGGCAGGTATCTTTGCCGTTGATGGAACCCCCACCGACTGCGTAAATCTCGGAATTCACACCCTTCTGGCC
GAAGCGCCCGATATCGTGGTGTCCGGCGTCAATCGCGGCGGGAACCTGGGCGACGACATTACGTACTCCGGGACCGTCTC
CGCAGCCTTGGAGGCGACCCTCATGGGAATTCCCGCCATTGCCGTTTCTCTTGCAACAAACGGACATGGGAGCAACTACC
GCGCGGCGGCTGCCTTTGCAGCACAGCTGGCAAGGGAAGTGCTCGACCGGGGCCTCCCCCGGGATACGTTCCTGAATGTC
AATGTCCCCGACCTGCCTGCCGAAGAGCTTGGTGGTCCGGTTATAACTTCGCAGGGAAAGCGTGATTACGGTGGTGACAT
CGTTACCAAGGTAGATCCGCGCGGCAGGAACTACTACTGGATCGGCGGCAACGAGCCGGTCTTTCGCGATATCGAGGGAA
CCGACTTTCACGCCGTCAAGCGCGGCAGGATCTCGGTTACCCCGCTTCACCTGGATCTGACGAATTACGCATCGCTCTCG
ATTTTGCAGTCGTGGGACCTTTCGGCATGCCGCCCGGAGGCTGGACAGCCGTCGGGAGCTCTGCTATAG

Upstream 100 bases:

>100_bases
TTTACAGGGGGTTACGAGATATATTTCGTAACCCCCTTTTGCGTATCGTCCGCCGGAAGCGAAGGTCCCGCCGGCATGCA
TCCGGAGGCAAGGAGGCGCC

Downstream 100 bases:

>100_bases
TCGCGTTTCCACCAACAGGGGCATGTTATGAACTTTGAAATTGCACGCAAACGGATGGTCGAATCCCAGATCATCGCGCG
AGGCGTCTCGGACCGGCGGG

Product: stationary phase survival protein SurE

Products: NA

Alternate protein names: Nucleoside 5'-monophosphate phosphohydrolase

Number of amino acids: Translated: 262; Mature: 262

Protein sequence:

>262_residues
MNILVTNDDGVHAPGIVALAEALRLVGTVTVVAPDRERSAVGHALTLHHPLRVTEIMAGIFAVDGTPTDCVNLGIHTLLA
EAPDIVVSGVNRGGNLGDDITYSGTVSAALEATLMGIPAIAVSLATNGHGSNYRAAAAFAAQLAREVLDRGLPRDTFLNV
NVPDLPAEELGGPVITSQGKRDYGGDIVTKVDPRGRNYYWIGGNEPVFRDIEGTDFHAVKRGRISVTPLHLDLTNYASLS
ILQSWDLSACRPEAGQPSGALL

Sequences:

>Translated_262_residues
MNILVTNDDGVHAPGIVALAEALRLVGTVTVVAPDRERSAVGHALTLHHPLRVTEIMAGIFAVDGTPTDCVNLGIHTLLA
EAPDIVVSGVNRGGNLGDDITYSGTVSAALEATLMGIPAIAVSLATNGHGSNYRAAAAFAAQLAREVLDRGLPRDTFLNV
NVPDLPAEELGGPVITSQGKRDYGGDIVTKVDPRGRNYYWIGGNEPVFRDIEGTDFHAVKRGRISVTPLHLDLTNYASLS
ILQSWDLSACRPEAGQPSGALL
>Mature_262_residues
MNILVTNDDGVHAPGIVALAEALRLVGTVTVVAPDRERSAVGHALTLHHPLRVTEIMAGIFAVDGTPTDCVNLGIHTLLA
EAPDIVVSGVNRGGNLGDDITYSGTVSAALEATLMGIPAIAVSLATNGHGSNYRAAAAFAAQLAREVLDRGLPRDTFLNV
NVPDLPAEELGGPVITSQGKRDYGGDIVTKVDPRGRNYYWIGGNEPVFRDIEGTDFHAVKRGRISVTPLHLDLTNYASLS
ILQSWDLSACRPEAGQPSGALL

Specific function: Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates

COG id: COG0496

COG function: function code R; Predicted acid phosphatase

Gene ontology:

Cell location: Cytoplasm (Potential)

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the surE nucleotidase family

Homologues:

Organism=Escherichia coli, GI1789101, Length=246, Percent_Identity=47.9674796747967, Blast_Score=212, Evalue=2e-56,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): SURE_GEOSL (Q74CZ6)

Other databases:

- EMBL:   AE017180
- RefSeq:   NP_952574.1
- ProteinModelPortal:   Q74CZ6
- SMR:   Q74CZ6
- GeneID:   2685252
- GenomeReviews:   AE017180_GR
- KEGG:   gsu:GSU1523
- NMPDR:   fig|243231.1.peg.1512
- TIGR:   GSU1523
- HOGENOM:   HBG600532
- OMA:   NGFYYVN
- ProtClustDB:   PRK00346
- BioCyc:   GSUL243231:GSU_1523-MONOMER
- BRENDA:   3.1.3.5
- GO:   GO:0005737
- HAMAP:   MF_00060
- InterPro:   IPR002828
- Gene3D:   G3DSA:3.40.1210.10
- TIGRFAMs:   TIGR00087

Pfam domain/function: PF01975 SurE; SSF64167 SurE-like_Pase/nucleotidase

EC number: =3.1.3.5

Molecular weight: Translated: 27542; Mature: 27542

Theoretical pI: Translated: 5.06; Mature: 5.06

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
1.1 %Met     (Translated Protein)
1.9 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
1.1 %Met     (Mature Protein)
1.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNILVTNDDGVHAPGIVALAEALRLVGTVTVVAPDRERSAVGHALTLHHPLRVTEIMAGI
CEEEEECCCCCCCCHHHHHHHHHHHHEEEEEEECCCHHHHHCCEEEECCCHHHHHHHHHH
FAVDGTPTDCVNLGIHTLLAEAPDIVVSGVNRGGNLGDDITYSGTVSAALEATLMGIPAI
EEECCCCHHHHHHHHHHHHHCCCCEEEECCCCCCCCCCCCEECCCHHHHHHHHHHCCCEE
AVSLATNGHGSNYRAAAAFAAQLAREVLDRGLPRDTFLNVNVPDLPAEELGGPVITSQGK
EEEEEECCCCCCCHHHHHHHHHHHHHHHHCCCCCCEEEECCCCCCCHHHHCCCEEECCCC
RDYGGDIVTKVDPRGRNYYWIGGNEPVFRDIEGTDFHAVKRGRISVTPLHLDLTNYASLS
CCCCCCEEEEECCCCCEEEEECCCCCEEECCCCCCEEEEECCCEEEEEEEEECCCCCEEE
ILQSWDLSACRPEAGQPSGALL
EEECCCCCCCCCCCCCCCCCCC
>Mature Secondary Structure
MNILVTNDDGVHAPGIVALAEALRLVGTVTVVAPDRERSAVGHALTLHHPLRVTEIMAGI
CEEEEECCCCCCCCHHHHHHHHHHHHEEEEEEECCCHHHHHCCEEEECCCHHHHHHHHHH
FAVDGTPTDCVNLGIHTLLAEAPDIVVSGVNRGGNLGDDITYSGTVSAALEATLMGIPAI
EEECCCCHHHHHHHHHHHHHCCCCEEEECCCCCCCCCCCCEECCCHHHHHHHHHHCCCEE
AVSLATNGHGSNYRAAAAFAAQLAREVLDRGLPRDTFLNVNVPDLPAEELGGPVITSQGK
EEEEEECCCCCCCHHHHHHHHHHHHHHHHCCCCCCEEEECCCCCCCHHHHCCCEEECCCC
RDYGGDIVTKVDPRGRNYYWIGGNEPVFRDIEGTDFHAVKRGRISVTPLHLDLTNYASLS
CCCCCCEEEEECCCCCEEEEECCCCCEEECCCCCCEEEEECCCEEEEEEEEECCCCCEEE
ILQSWDLSACRPEAGQPSGALL
EEECCCCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA