BacMap

Definition	Geobacter sulfurreducens PCA chromosome, complete genome.
Accession	NC_002939
Length	3,814,139

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The map label for this gene is crt [H]

Identifier: 39996479

GI number: 39996479

Start: 1505701

End: 1506483

Strand: Reverse

Name: crt [H]

Synonym: GSU1377

Alternate gene names: 39996479

Gene position: 1506483-1505701 (Counterclockwise)

Preceding gene: 39996496

Following gene: 39996478

Centisome position: 39.5

GC content: 66.67

Gene sequence:

>783_bases
ATGAACGGATACCATCTGCTGCTGGAGATCAGCGAAGGAATCGCCGCCATCACGATCAACAGACCGAGCGCCATGAACGC
CATGACTCCCGCAACCCTGGACGAGCTGGCCGAGGCGGTCCGGCGGGTGAACGGCGCCCCCGAGGTCCGGGCCGCGATCC
TGACCGGCGCCGGGACCAAGGCCTTCATGGCGGGCGCCGACATCGCCGCCATGCGGGACATGACACCGGCCCAGGCGCGG
GATCTGGCCCGGCAGGCCCACCAGATCTATGCCGACATCGAACGGTCTCCCAAGACCTTCATCGCGGCGGTCAACGGCTA
CGCCCTGGGCGGCGGGTGCGAACTGGCCATGGCCTGCGACATCCGGCTCGCCTCGGAGAACGCGAAATTCGGCCAACCGG
AGATCAACATCGGCATCATCCCCGGCTTCGGGGGCACCCAGCGGCTTCCCCGGCTGGTGGGCAAAGGGCGGGCCCTGGAG
ATGATCCTTACCGGCGAGATGATTGACGCCCGGGAGGCCCACCGCATCGGACTGGTGAACCGGGTGGTGACCCAGGAAGA
ACTGCCGGAGGAGGCCCGGCGGCTGGCCCGCGCCATTGCCGCCAAGGGCATGGTTGCCGTGGGACTCTGCAAGGAAGCGG
TAAACAACGGCCTGAACATGGAACTGACCAAGGCATGCGCCTACGAGGCCGAGCTCTTTGCCCACAGCTTCTCCACGGCG
GACCAGAAGGAAGGTATGAGCGCCTTTCTGGAGAAGCGCCCCGCCGTGTTTCGCGACTGCTGA

Upstream 100 bases:

>100_bases
GACAGCCGGCACCGCGGAAATTCGTCCCGTCCGGCGCGGCATCGGGCGGACACTGCTGAACCTACCATAGCCGGGCGACC
ACATCAACCGGGAGGAGACC

Downstream 100 bases:

>100_bases
ACGGCTGATGGAACCTGAAGCCGGTCAAGTGAGTGCTGTTGAATGTTGATTGAACGACGAATCGCCCCGGGCTGCCCGGG
GCCGGGAGGATCAATGGAAA

Product: 3-hydroxybutyryl-CoA dehydratase

Products: NA

Alternate protein names: Crotonase [H]

Number of amino acids: Translated: 260; Mature: 260

Protein sequence:

>260_residues
MNGYHLLLEISEGIAAITINRPSAMNAMTPATLDELAEAVRRVNGAPEVRAAILTGAGTKAFMAGADIAAMRDMTPAQAR
DLARQAHQIYADIERSPKTFIAAVNGYALGGGCELAMACDIRLASENAKFGQPEINIGIIPGFGGTQRLPRLVGKGRALE
MILTGEMIDAREAHRIGLVNRVVTQEELPEEARRLARAIAAKGMVAVGLCKEAVNNGLNMELTKACAYEAELFAHSFSTA
DQKEGMSAFLEKRPAVFRDC

Sequences:

>Translated_260_residues
MNGYHLLLEISEGIAAITINRPSAMNAMTPATLDELAEAVRRVNGAPEVRAAILTGAGTKAFMAGADIAAMRDMTPAQAR
DLARQAHQIYADIERSPKTFIAAVNGYALGGGCELAMACDIRLASENAKFGQPEINIGIIPGFGGTQRLPRLVGKGRALE
MILTGEMIDAREAHRIGLVNRVVTQEELPEEARRLARAIAAKGMVAVGLCKEAVNNGLNMELTKACAYEAELFAHSFSTA
DQKEGMSAFLEKRPAVFRDC
>Mature_260_residues
MNGYHLLLEISEGIAAITINRPSAMNAMTPATLDELAEAVRRVNGAPEVRAAILTGAGTKAFMAGADIAAMRDMTPAQAR
DLARQAHQIYADIERSPKTFIAAVNGYALGGGCELAMACDIRLASENAKFGQPEINIGIIPGFGGTQRLPRLVGKGRALE
MILTGEMIDAREAHRIGLVNRVVTQEELPEEARRLARAIAAKGMVAVGLCKEAVNNGLNMELTKACAYEAELFAHSFSTA
DQKEGMSAFLEKRPAVFRDC

Specific function: Could Possibly Oxidizes Fatty Acids Using Specific Components (By Similarity). [C]

COG id: COG1024

COG function: function code I; Enoyl-CoA hydratase/carnithine racemase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the enoyl-CoA hydratase/isomerase family [H]

Homologues:

Organism=Homo sapiens, GI194097323, Length=246, Percent_Identity=47.5609756097561, Blast_Score=217, Evalue=7e-57,
Organism=Homo sapiens, GI4502327, Length=256, Percent_Identity=36.71875, Blast_Score=137, Evalue=9e-33,
Organism=Homo sapiens, GI20127408, Length=217, Percent_Identity=35.4838709677419, Blast_Score=125, Evalue=3e-29,
Organism=Homo sapiens, GI31542718, Length=253, Percent_Identity=32.4110671936759, Blast_Score=124, Evalue=6e-29,
Organism=Homo sapiens, GI68989263, Length=212, Percent_Identity=32.5471698113208, Blast_Score=113, Evalue=2e-25,
Organism=Homo sapiens, GI150378541, Length=251, Percent_Identity=31.4741035856574, Blast_Score=110, Evalue=1e-24,
Organism=Homo sapiens, GI70995211, Length=250, Percent_Identity=31.2, Blast_Score=107, Evalue=1e-23,
Organism=Homo sapiens, GI213417737, Length=229, Percent_Identity=29.2576419213974, Blast_Score=100, Evalue=2e-21,
Organism=Homo sapiens, GI157694516, Length=229, Percent_Identity=29.2576419213974, Blast_Score=100, Evalue=2e-21,
Organism=Homo sapiens, GI37594469, Length=186, Percent_Identity=31.7204301075269, Blast_Score=100, Evalue=2e-21,
Organism=Homo sapiens, GI37594471, Length=186, Percent_Identity=31.7204301075269, Blast_Score=99, Evalue=3e-21,
Organism=Homo sapiens, GI261878539, Length=114, Percent_Identity=39.4736842105263, Blast_Score=88, Evalue=9e-18,
Organism=Homo sapiens, GI157694520, Length=208, Percent_Identity=29.3269230769231, Blast_Score=82, Evalue=5e-16,
Organism=Homo sapiens, GI62530384, Length=206, Percent_Identity=25.7281553398058, Blast_Score=81, Evalue=1e-15,
Organism=Homo sapiens, GI221136756, Length=254, Percent_Identity=25.9842519685039, Blast_Score=81, Evalue=1e-15,
Organism=Homo sapiens, GI221136753, Length=254, Percent_Identity=25.9842519685039, Blast_Score=81, Evalue=1e-15,
Organism=Homo sapiens, GI25453481, Length=253, Percent_Identity=23.7154150197628, Blast_Score=80, Evalue=2e-15,
Organism=Homo sapiens, GI51538573, Length=253, Percent_Identity=23.7154150197628, Blast_Score=80, Evalue=2e-15,
Organism=Homo sapiens, GI221307494, Length=253, Percent_Identity=26.0869565217391, Blast_Score=80, Evalue=2e-15,
Organism=Homo sapiens, GI4757968, Length=257, Percent_Identity=23.7354085603113, Blast_Score=80, Evalue=2e-15,
Organism=Homo sapiens, GI49355787, Length=257, Percent_Identity=23.7354085603113, Blast_Score=80, Evalue=2e-15,
Organism=Homo sapiens, GI4757966, Length=246, Percent_Identity=23.9837398373984, Blast_Score=77, Evalue=2e-14,
Organism=Homo sapiens, GI51538581, Length=246, Percent_Identity=23.9837398373984, Blast_Score=77, Evalue=2e-14,
Organism=Homo sapiens, GI260274832, Length=220, Percent_Identity=28.1818181818182, Blast_Score=73, Evalue=3e-13,
Organism=Homo sapiens, GI45643119, Length=220, Percent_Identity=28.1818181818182, Blast_Score=73, Evalue=3e-13,
Organism=Homo sapiens, GI260275230, Length=220, Percent_Identity=28.1818181818182, Blast_Score=73, Evalue=3e-13,
Organism=Homo sapiens, GI116235487, Length=253, Percent_Identity=24.1106719367589, Blast_Score=70, Evalue=1e-12,
Organism=Homo sapiens, GI295842266, Length=204, Percent_Identity=23.0392156862745, Blast_Score=65, Evalue=4e-11,
Organism=Escherichia coli, GI1787659, Length=254, Percent_Identity=39.3700787401575, Blast_Score=167, Evalue=5e-43,
Organism=Escherichia coli, GI221142681, Length=249, Percent_Identity=38.5542168674699, Blast_Score=144, Evalue=5e-36,
Organism=Escherichia coli, GI1788682, Length=190, Percent_Identity=41.5789473684211, Blast_Score=134, Evalue=7e-33,
Organism=Escherichia coli, GI1790281, Length=191, Percent_Identity=37.696335078534, Blast_Score=130, Evalue=6e-32,
Organism=Escherichia coli, GI1787660, Length=257, Percent_Identity=35.408560311284, Blast_Score=125, Evalue=2e-30,
Organism=Escherichia coli, GI1788597, Length=253, Percent_Identity=33.9920948616601, Blast_Score=125, Evalue=3e-30,
Organism=Escherichia coli, GI87082183, Length=256, Percent_Identity=30.859375, Blast_Score=108, Evalue=3e-25,
Organism=Caenorhabditis elegans, GI25145438, Length=244, Percent_Identity=44.2622950819672, Blast_Score=187, Evalue=4e-48,
Organism=Caenorhabditis elegans, GI17554946, Length=243, Percent_Identity=43.2098765432099, Blast_Score=184, Evalue=4e-47,
Organism=Caenorhabditis elegans, GI17540714, Length=225, Percent_Identity=37.3333333333333, Blast_Score=162, Evalue=1e-40,
Organism=Caenorhabditis elegans, GI17534483, Length=258, Percent_Identity=29.8449612403101, Blast_Score=120, Evalue=1e-27,
Organism=Caenorhabditis elegans, GI17560910, Length=238, Percent_Identity=33.6134453781513, Blast_Score=118, Evalue=3e-27,
Organism=Caenorhabditis elegans, GI17558304, Length=174, Percent_Identity=36.7816091954023, Blast_Score=116, Evalue=1e-26,
Organism=Caenorhabditis elegans, GI17536985, Length=259, Percent_Identity=28.957528957529, Blast_Score=104, Evalue=5e-23,
Organism=Caenorhabditis elegans, GI25144276, Length=174, Percent_Identity=33.3333333333333, Blast_Score=100, Evalue=1e-21,
Organism=Caenorhabditis elegans, GI17508951, Length=174, Percent_Identity=33.3333333333333, Blast_Score=100, Evalue=1e-21,
Organism=Caenorhabditis elegans, GI17508953, Length=174, Percent_Identity=33.9080459770115, Blast_Score=99, Evalue=3e-21,
Organism=Caenorhabditis elegans, GI25144157, Length=198, Percent_Identity=28.2828282828283, Blast_Score=91, Evalue=4e-19,
Organism=Caenorhabditis elegans, GI25144160, Length=198, Percent_Identity=28.2828282828283, Blast_Score=91, Evalue=4e-19,
Organism=Caenorhabditis elegans, GI17540306, Length=240, Percent_Identity=28.75, Blast_Score=91, Evalue=6e-19,
Organism=Caenorhabditis elegans, GI17549921, Length=211, Percent_Identity=25.5924170616114, Blast_Score=87, Evalue=6e-18,
Organism=Caenorhabditis elegans, GI25141363, Length=189, Percent_Identity=25.9259259259259, Blast_Score=74, Evalue=6e-14,
Organism=Caenorhabditis elegans, GI17535521, Length=246, Percent_Identity=24.7967479674797, Blast_Score=70, Evalue=7e-13,
Organism=Saccharomyces cerevisiae, GI6320241, Length=200, Percent_Identity=26.5, Blast_Score=86, Evalue=6e-18,
Organism=Drosophila melanogaster, GI20129971, Length=248, Percent_Identity=47.9838709677419, Blast_Score=223, Evalue=7e-59,
Organism=Drosophila melanogaster, GI24653477, Length=248, Percent_Identity=47.9838709677419, Blast_Score=223, Evalue=7e-59,
Organism=Drosophila melanogaster, GI24653139, Length=268, Percent_Identity=36.5671641791045, Blast_Score=168, Evalue=4e-42,
Organism=Drosophila melanogaster, GI19922422, Length=253, Percent_Identity=28.4584980237154, Blast_Score=124, Evalue=8e-29,
Organism=Drosophila melanogaster, GI19920382, Length=216, Percent_Identity=34.7222222222222, Blast_Score=105, Evalue=4e-23,
Organism=Drosophila melanogaster, GI19921000, Length=183, Percent_Identity=37.1584699453552, Blast_Score=103, Evalue=1e-22,
Organism=Drosophila melanogaster, GI24583077, Length=183, Percent_Identity=37.1584699453552, Blast_Score=103, Evalue=1e-22,
Organism=Drosophila melanogaster, GI24583079, Length=183, Percent_Identity=37.1584699453552, Blast_Score=103, Evalue=1e-22,
Organism=Drosophila melanogaster, GI21357171, Length=191, Percent_Identity=32.9842931937173, Blast_Score=96, Evalue=2e-20,
Organism=Drosophila melanogaster, GI24650670, Length=248, Percent_Identity=29.8387096774194, Blast_Score=88, Evalue=6e-18,
Organism=Drosophila melanogaster, GI28571729, Length=175, Percent_Identity=29.1428571428571, Blast_Score=86, Evalue=2e-17,
Organism=Drosophila melanogaster, GI28571730, Length=175, Percent_Identity=29.1428571428571, Blast_Score=86, Evalue=3e-17,
Organism=Drosophila melanogaster, GI24654903, Length=191, Percent_Identity=27.2251308900524, Blast_Score=80, Evalue=2e-15,
Organism=Drosophila melanogaster, GI19921018, Length=179, Percent_Identity=31.2849162011173, Blast_Score=77, Evalue=1e-14,
Organism=Drosophila melanogaster, GI24583165, Length=179, Percent_Identity=29.0502793296089, Blast_Score=71, Evalue=9e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014748
- InterPro:   IPR001753
- InterPro:   IPR018376 [H]

Pfam domain/function: PF00378 ECH [H]

EC number: =4.2.1.55 [H]

Molecular weight: Translated: 27813; Mature: 27813

Theoretical pI: Translated: 6.52; Mature: 6.52

Prosite motif: PS00166 ENOYL_COA_HYDRATASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.9 %Cys     (Translated Protein)
4.6 %Met     (Translated Protein)
6.5 %Cys+Met (Translated Protein)
1.9 %Cys     (Mature Protein)
4.6 %Met     (Mature Protein)
6.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNGYHLLLEISEGIAAITINRPSAMNAMTPATLDELAEAVRRVNGAPEVRAAILTGAGTK
CCCEEEEEEECCCEEEEEECCCCCCCCCCCHHHHHHHHHHHHCCCCCHHEEEEEECCCCH
AFMAGADIAAMRDMTPAQARDLARQAHQIYADIERSPKTFIAAVNGYALGGGCELAMACD
HHHCCCCHHHHHCCCHHHHHHHHHHHHHHHHHHCCCCCEEEEEECCEEECCCCEEEEEEE
IRLASENAKFGQPEINIGIIPGFGGTQRLPRLVGKGRALEMILTGEMIDAREAHRIGLVN
EEEECCCCCCCCCCEEEEEECCCCCHHHHHHHHCCCCEEEEEEECCHHCHHHHHHHHHHH
RVVTQEELPEEARRLARAIAAKGMVAVGLCKEAVNNGLNMELTKACAYEAELFAHSFSTA
HHHHHHHCHHHHHHHHHHHHHCCHHHHHHHHHHHCCCCCEEHHHHHHHHHHHHHHHHCCC
DQKEGMSAFLEKRPAVFRDC
HHHHHHHHHHHHCCCHHCCC
>Mature Secondary Structure
MNGYHLLLEISEGIAAITINRPSAMNAMTPATLDELAEAVRRVNGAPEVRAAILTGAGTK
CCCEEEEEEECCCEEEEEECCCCCCCCCCCHHHHHHHHHHHHCCCCCHHEEEEEECCCCH
AFMAGADIAAMRDMTPAQARDLARQAHQIYADIERSPKTFIAAVNGYALGGGCELAMACD
HHHCCCCHHHHHCCCHHHHHHHHHHHHHHHHHHCCCCCEEEEEECCEEECCCCEEEEEEE
IRLASENAKFGQPEINIGIIPGFGGTQRLPRLVGKGRALEMILTGEMIDAREAHRIGLVN
EEEECCCCCCCCCCEEEEEECCCCCHHHHHHHHCCCCEEEEEEECCHHCHHHHHHHHHHH
RVVTQEELPEEARRLARAIAAKGMVAVGLCKEAVNNGLNMELTKACAYEAELFAHSFSTA
HHHHHHHCHHHHHHHHHHHHHCCHHHHHHHHHHHCCCCCEEHHHHHHHHHHHHHHHHCCC
DQKEGMSAFLEKRPAVFRDC
HHHHHHHHHHHHCCCHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8655474; 11466286 [H]