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The map label for this gene is acuC [H]

Identifier: 39996324

GI number: 39996324

Start: 1326135

End: 1327292

Strand: Direct

Name: acuC [H]

Synonym: GSU1222

Alternate gene names: 39996324

Gene position: 1326135-1327292 (Clockwise)

Preceding gene: 39996321

Following gene: 39996325

Centisome position: 34.77

GC content: 61.49

Gene sequence:

>1158_bases
TTGCCAGCCAGAACAGCCCTCATATACTCGAACGATTTCGCCCGGTTCAGCTACGGCGACGATCACCCGTTCAAGATCCA
GCGTTTCATTCTCGCCTTTGAGCTCATGCGCGCCTATGGCCTCATGGAGCTTCCGAACGTCAAAATCCTCGACTGCCCCC
GAGCTGCGGAAGAGGCACTGCTTACCTTTCACGCGCCCGACTATCTCGATCGTCTCAGGGAATTCAGCGAGTCGGACGAT
GCCCGCGCCGATTTCCGGTACGGTCTCGGCGATCTGGACAACCCGGTTTTCCGGGGGCTCTACGACTGGGCACGGCTGGG
TGCCGGAGGGACCATCGAGGCGGCCCGGCTGGTTGCCGAGGAGGGCTATGACATCGCCTTCAATCTTGCGGGGGGGTGGC
ATCACGCCCATCGGGCCAAGGCATCGGGATTCTCCTATCTGAACGACGCGGTCGTGGCCATCAACCTGCTCCTGGAAAAG
GGCCTGCGGGTGGCGTACCTCGATATCGATGCCCACCACGGCGACGGAGTGCAGGAAGCGTTTTACGATACGGACCGGGT
CCTGACCATTTCGATTCACGAGAGCGGCATGTACTTCTTTCCCGGCACCGGTTTCGAGGGGGAAACCGGCACCGGCGCGG
GCACGGGGTATTCGGTCAATATCCCGCTGGTGGCCCACGCCGACGATGCGCTTTTCATGAAGGCCTTCGACGAAGTGGCG
TTTCCGCTTCTCGCCGCCTATAATCCCGACGTCCTCGTGACTCAACTGGGCGCCGACACCTTCCGTACCGATCCTCTCAC
GCGGCTTGAGGTGACGACTCATAGCTACACCTATATCCTGCGCAAGCTCAAGGCGCTCGGCATCCCCTGGGTTGCCGTGG
GAGGGGGCGGATACAACCTGGTCAATGTGGCCAGGGCCTGGACCCTTGCCTGGGGGGTGATGAACGGGGTCGAACTGCCG
CCCCGACTGCCGGATTCGTTTGTGTCGATCATCGGCCGGCTCGGCTATCCCAACAGGATGCTCCTCGATGCCATGCACTG
GGCCCAGGAGGACGACCGCAACCAGGCACTGGACGCGGTGGAGCGAAGCATAGCTGTCATCCGGAAGACGATTTTTCCGG
TGATCATCGGTTCCTATGGCGAGACTTCCGGGGAATGA

Upstream 100 bases:

>100_bases
GCCGGGGAAAATAGGGGTTGACGGGGGGATGTCTACATTGTAAATTCGCGTGGTTAAAAGAAATTGAGGCTATTTGCGTC
TTTCTGTTACGGGAATTCTA

Downstream 100 bases:

>100_bases
GCCGCTGGTGTCGGCCTCGGGCCGCGAACTCCATACCCTGCGCGAGGTCAATGGTCTCGCCCCGGCGGAGCGCGACCGGG
TTTACGCCGGACTGATTCCA

Product: histone deacetylase/AcuC/AphA family protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 385; Mature: 384

Protein sequence:

>385_residues
MPARTALIYSNDFARFSYGDDHPFKIQRFILAFELMRAYGLMELPNVKILDCPRAAEEALLTFHAPDYLDRLREFSESDD
ARADFRYGLGDLDNPVFRGLYDWARLGAGGTIEAARLVAEEGYDIAFNLAGGWHHAHRAKASGFSYLNDAVVAINLLLEK
GLRVAYLDIDAHHGDGVQEAFYDTDRVLTISIHESGMYFFPGTGFEGETGTGAGTGYSVNIPLVAHADDALFMKAFDEVA
FPLLAAYNPDVLVTQLGADTFRTDPLTRLEVTTHSYTYILRKLKALGIPWVAVGGGGYNLVNVARAWTLAWGVMNGVELP
PRLPDSFVSIIGRLGYPNRMLLDAMHWAQEDDRNQALDAVERSIAVIRKTIFPVIIGSYGETSGE

Sequences:

>Translated_385_residues
MPARTALIYSNDFARFSYGDDHPFKIQRFILAFELMRAYGLMELPNVKILDCPRAAEEALLTFHAPDYLDRLREFSESDD
ARADFRYGLGDLDNPVFRGLYDWARLGAGGTIEAARLVAEEGYDIAFNLAGGWHHAHRAKASGFSYLNDAVVAINLLLEK
GLRVAYLDIDAHHGDGVQEAFYDTDRVLTISIHESGMYFFPGTGFEGETGTGAGTGYSVNIPLVAHADDALFMKAFDEVA
FPLLAAYNPDVLVTQLGADTFRTDPLTRLEVTTHSYTYILRKLKALGIPWVAVGGGGYNLVNVARAWTLAWGVMNGVELP
PRLPDSFVSIIGRLGYPNRMLLDAMHWAQEDDRNQALDAVERSIAVIRKTIFPVIIGSYGETSGE
>Mature_384_residues
PARTALIYSNDFARFSYGDDHPFKIQRFILAFELMRAYGLMELPNVKILDCPRAAEEALLTFHAPDYLDRLREFSESDDA
RADFRYGLGDLDNPVFRGLYDWARLGAGGTIEAARLVAEEGYDIAFNLAGGWHHAHRAKASGFSYLNDAVVAINLLLEKG
LRVAYLDIDAHHGDGVQEAFYDTDRVLTISIHESGMYFFPGTGFEGETGTGAGTGYSVNIPLVAHADDALFMKAFDEVAF
PLLAAYNPDVLVTQLGADTFRTDPLTRLEVTTHSYTYILRKLKALGIPWVAVGGGGYNLVNVARAWTLAWGVMNGVELPP
RLPDSFVSIIGRLGYPNRMLLDAMHWAQEDDRNQALDAVERSIAVIRKTIFPVIIGSYGETSGE

Specific function: Role in growth and sporulation on acetoin or butanediol. Involved in the breakdown of these compounds used as a carbon source [H]

COG id: COG0123

COG function: function code BQ; Deacetylases, including yeast histone deacetylase and acetoin utilization protein

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the histone deacetylase family [H]

Homologues:

Organism=Homo sapiens, GI13128860, Length=324, Percent_Identity=37.962962962963, Blast_Score=228, Evalue=1e-59,
Organism=Homo sapiens, GI13128862, Length=329, Percent_Identity=37.6899696048632, Blast_Score=221, Evalue=1e-57,
Organism=Homo sapiens, GI8923769, Length=321, Percent_Identity=38.9408099688474, Blast_Score=211, Evalue=8e-55,
Organism=Homo sapiens, GI293336691, Length=325, Percent_Identity=37.2307692307692, Blast_Score=209, Evalue=5e-54,
Organism=Homo sapiens, GI262073088, Length=192, Percent_Identity=41.6666666666667, Blast_Score=153, Evalue=2e-37,
Organism=Homo sapiens, GI262073092, Length=219, Percent_Identity=41.5525114155251, Blast_Score=151, Evalue=8e-37,
Organism=Homo sapiens, GI17158039, Length=248, Percent_Identity=30.241935483871, Blast_Score=103, Evalue=3e-22,
Organism=Homo sapiens, GI30795204, Length=248, Percent_Identity=30.241935483871, Blast_Score=103, Evalue=3e-22,
Organism=Homo sapiens, GI30795202, Length=248, Percent_Identity=30.241935483871, Blast_Score=103, Evalue=3e-22,
Organism=Homo sapiens, GI13128864, Length=324, Percent_Identity=28.0864197530864, Blast_Score=102, Evalue=5e-22,
Organism=Homo sapiens, GI153085395, Length=249, Percent_Identity=30.5220883534137, Blast_Score=101, Evalue=2e-21,
Organism=Homo sapiens, GI20070354, Length=334, Percent_Identity=29.0419161676647, Blast_Score=97, Evalue=3e-20,
Organism=Homo sapiens, GI148539870, Length=215, Percent_Identity=30.6976744186047, Blast_Score=90, Evalue=4e-18,
Organism=Homo sapiens, GI169234807, Length=215, Percent_Identity=30.6976744186047, Blast_Score=89, Evalue=6e-18,
Organism=Homo sapiens, GI62750347, Length=231, Percent_Identity=31.6017316017316, Blast_Score=89, Evalue=9e-18,
Organism=Homo sapiens, GI62750349, Length=231, Percent_Identity=31.6017316017316, Blast_Score=89, Evalue=9e-18,
Organism=Homo sapiens, GI209862883, Length=285, Percent_Identity=25.6140350877193, Blast_Score=86, Evalue=6e-17,
Organism=Homo sapiens, GI217272877, Length=288, Percent_Identity=26.3888888888889, Blast_Score=84, Evalue=2e-16,
Organism=Homo sapiens, GI226529806, Length=334, Percent_Identity=27.8443113772455, Blast_Score=75, Evalue=8e-14,
Organism=Caenorhabditis elegans, GI17534739, Length=327, Percent_Identity=37.9204892966361, Blast_Score=233, Evalue=2e-61,
Organism=Caenorhabditis elegans, GI17508561, Length=327, Percent_Identity=38.2262996941896, Blast_Score=231, Evalue=6e-61,
Organism=Caenorhabditis elegans, GI17561978, Length=379, Percent_Identity=34.5646437994723, Blast_Score=216, Evalue=2e-56,
Organism=Caenorhabditis elegans, GI17540334, Length=334, Percent_Identity=29.6407185628743, Blast_Score=112, Evalue=5e-25,
Organism=Caenorhabditis elegans, GI193206283, Length=334, Percent_Identity=29.6407185628743, Blast_Score=111, Evalue=6e-25,
Organism=Caenorhabditis elegans, GI17540332, Length=334, Percent_Identity=29.6407185628743, Blast_Score=111, Evalue=6e-25,
Organism=Caenorhabditis elegans, GI193209491, Length=213, Percent_Identity=32.3943661971831, Blast_Score=97, Evalue=2e-20,
Organism=Caenorhabditis elegans, GI17537347, Length=318, Percent_Identity=26.4150943396226, Blast_Score=91, Evalue=8e-19,
Organism=Saccharomyces cerevisiae, GI6323999, Length=324, Percent_Identity=40.1234567901235, Blast_Score=243, Evalue=5e-65,
Organism=Saccharomyces cerevisiae, GI6321244, Length=326, Percent_Identity=36.8098159509202, Blast_Score=231, Evalue=1e-61,
Organism=Saccharomyces cerevisiae, GI6324307, Length=333, Percent_Identity=33.3333333333333, Blast_Score=127, Evalue=2e-30,
Organism=Saccharomyces cerevisiae, GI6325325, Length=226, Percent_Identity=32.3008849557522, Blast_Score=117, Evalue=4e-27,
Organism=Drosophila melanogaster, GI24644244, Length=328, Percent_Identity=38.719512195122, Blast_Score=229, Evalue=2e-60,
Organism=Drosophila melanogaster, GI24657891, Length=324, Percent_Identity=37.962962962963, Blast_Score=223, Evalue=1e-58,
Organism=Drosophila melanogaster, GI281360899, Length=332, Percent_Identity=29.5180722891566, Blast_Score=110, Evalue=1e-24,
Organism=Drosophila melanogaster, GI24642142, Length=332, Percent_Identity=29.5180722891566, Blast_Score=110, Evalue=1e-24,
Organism=Drosophila melanogaster, GI24642144, Length=332, Percent_Identity=29.5180722891566, Blast_Score=110, Evalue=1e-24,
Organism=Drosophila melanogaster, GI24642146, Length=332, Percent_Identity=29.5180722891566, Blast_Score=110, Evalue=2e-24,
Organism=Drosophila melanogaster, GI281360799, Length=216, Percent_Identity=33.7962962962963, Blast_Score=104, Evalue=1e-22,
Organism=Drosophila melanogaster, GI24641720, Length=216, Percent_Identity=33.7962962962963, Blast_Score=103, Evalue=1e-22,
Organism=Drosophila melanogaster, GI281360801, Length=216, Percent_Identity=33.7962962962963, Blast_Score=103, Evalue=1e-22,
Organism=Drosophila melanogaster, GI24649807, Length=202, Percent_Identity=26.7326732673267, Blast_Score=77, Evalue=2e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003085
- InterPro:   IPR000286 [H]

Pfam domain/function: PF00850 Hist_deacetyl [H]

EC number: NA

Molecular weight: Translated: 42569; Mature: 42437

Theoretical pI: Translated: 4.78; Mature: 4.78

Prosite motif: PS00213 LIPOCALIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
2.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPARTALIYSNDFARFSYGDDHPFKIQRFILAFELMRAYGLMELPNVKILDCPRAAEEAL
CCCCEEEEEECCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCCEEEECCCHHHHHE
LTFHAPDYLDRLREFSESDDARADFRYGLGDLDNPVFRGLYDWARLGAGGTIEAARLVAE
EEECCHHHHHHHHHHCCCCCCCHHHHCCCCCCCCHHHHHHHHHHHHCCCCCHHHHHHHHH
EGYDIAFNLAGGWHHAHRAKASGFSYLNDAVVAINLLLEKGLRVAYLDIDAHHGDGVQEA
CCCEEEEECCCCHHHHHHHHHCCCHHHHHHHHHHHHHHHCCCEEEEEEEECCCCCCHHHH
FYDTDRVLTISIHESGMYFFPGTGFEGETGTGAGTGYSVNIPLVAHADDALFMKAFDEVA
HCCCCCEEEEEEECCCEEEECCCCCCCCCCCCCCCCEEEEEEEEEECCCHHHHHHHHHHH
FPLLAAYNPDVLVTQLGADTFRTDPLTRLEVTTHSYTYILRKLKALGIPWVAVGGGGYNL
HHHHHHCCCCEEEEECCCCCCCCCCCEEEEEEHHHHHHHHHHHHHCCCCEEEECCCCCHH
VNVARAWTLAWGVMNGVELPPRLPDSFVSIIGRLGYPNRMLLDAMHWAQEDDRNQALDAV
HHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHCCCCCHHHHHHHHHHCCCCHHHHHHHH
ERSIAVIRKTIFPVIIGSYGETSGE
HHHHHHHHHHHHHHEECCCCCCCCC
>Mature Secondary Structure 
PARTALIYSNDFARFSYGDDHPFKIQRFILAFELMRAYGLMELPNVKILDCPRAAEEAL
CCCEEEEEECCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCCEEEECCCHHHHHE
LTFHAPDYLDRLREFSESDDARADFRYGLGDLDNPVFRGLYDWARLGAGGTIEAARLVAE
EEECCHHHHHHHHHHCCCCCCCHHHHCCCCCCCCHHHHHHHHHHHHCCCCCHHHHHHHHH
EGYDIAFNLAGGWHHAHRAKASGFSYLNDAVVAINLLLEKGLRVAYLDIDAHHGDGVQEA
CCCEEEEECCCCHHHHHHHHHCCCHHHHHHHHHHHHHHHCCCEEEEEEEECCCCCCHHHH
FYDTDRVLTISIHESGMYFFPGTGFEGETGTGAGTGYSVNIPLVAHADDALFMKAFDEVA
HCCCCCEEEEEEECCCEEEECCCCCCCCCCCCCCCCEEEEEEEEEECCCHHHHHHHHHHH
FPLLAAYNPDVLVTQLGADTFRTDPLTRLEVTTHSYTYILRKLKALGIPWVAVGGGGYNL
HHHHHHCCCCEEEEECCCCCCCCCCCEEEEEEHHHHHHHHHHHHHCCCCEEEECCCCCHH
VNVARAWTLAWGVMNGVELPPRLPDSFVSIIGRLGYPNRMLLDAMHWAQEDDRNQALDAV
HHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHCCCCCHHHHHHHHHHCCCCHHHHHHHH
ERSIAVIRKTIFPVIIGSYGETSGE
HHHHHHHHHHHHHHEECCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 7934817; 9387221; 9384377 [H]