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The map label for this gene is cca [H]

Identifier: 39996308

GI number: 39996308

Start: 1310650

End: 1311246

Strand: Direct

Name: cca [H]

Synonym: GSU1206

Alternate gene names: 39996308

Gene position: 1310650-1311246 (Clockwise)

Preceding gene: 39996307

Following gene: 39996309

Centisome position: 34.36

GC content: 66.33

Gene sequence:

>597_bases
ATGAGCAACGGAACTGCACAGGGGGGCGAGACGGTCCCGGAGACCGCCCGTCACTGCCGTGAGCTCGTCGACCGCTGGCT
TGCCGACGGAAGCTTCGACCGGCGCCTCCCGGAGGTCGCGCGGCTGCGGGGCGTACCCCAGCCCGAGGTCTATCACGCCG
AGGGCGACGCTTTCGTCCATACGATGCTTGCTCTGTCGGCCGTAGACGGCGGGGCTGATTCGCGGGTCTTCTGGGGGGTG
CTCCTGCACGATATCGGCAAGGCGGAGACCACCGAGTTCATCAGCGGACGCTGGCGCGCCTGGGGTCATGCCGAGCGCGG
CGCAGCCATGGTGCCGGCAGTCATGGAGCGGTTGGGACTCCCGGAACTGGCCGCGGACGTGGTCTGGCTGGTCAGGCACC
ATACCTTCCATTTCTCCTGGAACCTGACGCCGGACGTGCGACTCACCCGTAACCAGCGCCGTTTCCTGGAGCATCCTCTG
TTGCCGTTGTTGCTGGAGGTCTGCCGCGCCGACGCGGACGGCTCCCATGGGGGTAGCGACAAGGGCGATAAGATCGAGCA
GATAGCGGATCTGCTCAACGACGAAAGGAGAGCATGA

Upstream 100 bases:

>100_bases
GGCATTACGGCCCCGTGGCCGTGGGGGCCCCCGACGAACGGATCGCCAATGAGGTGAACGTTCTCGCAACAACCTTCGCC
GAGCTGGTGAACCGCGTCCG

Downstream 100 bases:

>100_bases
CATGACGATCACTGATGCGGCAAAAGCGGTTCTCGCGCCGATTGTGGGGGAGCACCCCGGAAAGATTCTGCGTGTTGTCT
TTGAGGGGTTTGGTTGAGGC

Product: HDIG domain-containing protein

Products: NA

Alternate protein names: CCA-adding enzyme; tRNA CCA-pyrophosphorylase; tRNA adenylyl-/cytidylyl-transferase; tRNA nucleotidyltransferase; tRNA-NT; 2'-nucleotidase; 2',3'-cyclic phosphodiesterase; Phosphatase [H]

Number of amino acids: Translated: 198; Mature: 197

Protein sequence:

>198_residues
MSNGTAQGGETVPETARHCRELVDRWLADGSFDRRLPEVARLRGVPQPEVYHAEGDAFVHTMLALSAVDGGADSRVFWGV
LLHDIGKAETTEFISGRWRAWGHAERGAAMVPAVMERLGLPELAADVVWLVRHHTFHFSWNLTPDVRLTRNQRRFLEHPL
LPLLLEVCRADADGSHGGSDKGDKIEQIADLLNDERRA

Sequences:

>Translated_198_residues
MSNGTAQGGETVPETARHCRELVDRWLADGSFDRRLPEVARLRGVPQPEVYHAEGDAFVHTMLALSAVDGGADSRVFWGV
LLHDIGKAETTEFISGRWRAWGHAERGAAMVPAVMERLGLPELAADVVWLVRHHTFHFSWNLTPDVRLTRNQRRFLEHPL
LPLLLEVCRADADGSHGGSDKGDKIEQIADLLNDERRA
>Mature_197_residues
SNGTAQGGETVPETARHCRELVDRWLADGSFDRRLPEVARLRGVPQPEVYHAEGDAFVHTMLALSAVDGGADSRVFWGVL
LHDIGKAETTEFISGRWRAWGHAERGAAMVPAVMERLGLPELAADVVWLVRHHTFHFSWNLTPDVRLTRNQRRFLEHPLL
PLLLEVCRADADGSHGGSDKGDKIEQIADLLNDERRA

Specific function: Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing

COG id: COG0617

COG function: function code J; tRNA nucleotidyltransferase/poly(A) polymerase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the tRNA nucleotidyltransferase/poly(A) polymerase family. Bacterial CCA-adding enzyme type 1 subfamily [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR012006
- InterPro:   IPR003607
- InterPro:   IPR002646 [H]

Pfam domain/function: PF01743 PolyA_pol [H]

EC number: =2.7.7.21; =2.7.7.25 [H]

Molecular weight: Translated: 22100; Mature: 21969

Theoretical pI: Translated: 6.17; Mature: 6.17

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSNGTAQGGETVPETARHCRELVDRWLADGSFDRRLPEVARLRGVPQPEVYHAEGDAFVH
CCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCCCCCEEECCCHHHHH
TMLALSAVDGGADSRVFWGVLLHDIGKAETTEFISGRWRAWGHAERGAAMVPAVMERLGL
HHHHHHHHCCCCCCHHHHHHHHHHHCCHHHHHHHHCCHHCCCCCCCCCHHHHHHHHHCCC
PELAADVVWLVRHHTFHFSWNLTPDVRLTRNQRRFLEHPLLPLLLEVCRADADGSHGGSD
HHHHHHHHHHHHHHEEEEEECCCCCCEECHHHHHHHHCCHHHHHHHHHHCCCCCCCCCCC
KGDKIEQIADLLNDERRA
CCHHHHHHHHHHHHCCCC
>Mature Secondary Structure 
SNGTAQGGETVPETARHCRELVDRWLADGSFDRRLPEVARLRGVPQPEVYHAEGDAFVH
CCCCCCCCCCCHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCCCCCEEECCCHHHHH
TMLALSAVDGGADSRVFWGVLLHDIGKAETTEFISGRWRAWGHAERGAAMVPAVMERLGL
HHHHHHHHCCCCCCHHHHHHHHHHHCCHHHHHHHHCCHHCCCCCCCCCHHHHHHHHHCCC
PELAADVVWLVRHHTFHFSWNLTPDVRLTRNQRRFLEHPLLPLLLEVCRADADGSHGGSD
HHHHHHHHHHHHHHEEEEEECCCCCCEECHHHHHHHHCCHHHHHHHHHHCCCCCCCCCCC
KGDKIEQIADLLNDERRA
CCHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA