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The map label for this gene is frdB [H]

Identifier: 39996280

GI number: 39996280

Start: 1284438

End: 1285199

Strand: Direct

Name: frdB [H]

Synonym: GSU1178

Alternate gene names: 39996280

Gene position: 1284438-1285199 (Clockwise)

Preceding gene: 39996279

Following gene: 39996281

Centisome position: 33.68

GC content: 58.66

Gene sequence:

>762_bases
ATGAGCCATCACGACAAGAATATGACTCTTACCCTTCATGTCTGGCGCCAGAAGGGACCGAAGGACCCGGGGAAATTCGA
GGTCTACGAGGCGAAAGACGTCAGTCCCGACCAGTCGTTCCTCGAAATGCTCGACGACGTCAACGAGGAACTCATCAAGC
AGGGGAAGGACCCCATCGCCTTCGATCACGACTGCCGTGAGGGTATCTGCGGCATGTGCTCCCAGGTAATCAACGGCATT
CCACATGGCGGCATGGACCGGACAACGGTTTGTCAGCTCCACATGCGGATGTTCAAGAATGGCGATGCCATCTACATCGA
GCCGTGGCGTGCCCGCGCATTCCCGATCATCAAGGATCTGGTCGTTGACCGGGGAGCCCTCGACACCATTATCCAAGCAG
GCGGCTACACATCGGCCCATACCGGCGGAGTTGCCGACGGCAATGCCCTTCTCATCCCGAAGGACGATGCCGATTACGCC
ATGGACGCTGCCGAGTGCATCGGCTGTGGTGCTTGCGTGGCAGGCTGCCCCAACGGGTCGGCTATGCTGTTCACCTCTGC
CAAGGTGTCGCAGCTTGCGGTCCTGCCGCAGGGCAAAGCCGAAGCCACCCGTCGTGTCAAGGCAATGACCGAGACCTTGC
AGGAGTGCGGTTTCGGTAACTGTACCAACCACTACGAGTGCCAGGCTGCGTGTCCCAAGGGGATCAACGTGAAGTTCATC
GCTACGCTGAACAGGGAGTACCTCAAGTCTCTCTGCAAATAG

Upstream 100 bases:

>100_bases
CCGCCGCCTGGGAGTTCAAGGGTGTCGGCAAAGAGCCCGAGCTTCACAAGGAGCCGCTGAAGTTTGAAAACGTCCACCTT
GCTATAAGGAGCTACAAATA

Downstream 100 bases:

>100_bases
CGGACGCACAGTGGTTTTCGTACACTGCTACAGATGAATGGAAGGGGCGGATTGACAATCCGCCCCTATTTTTTGTACAC
CGCAGGGTACGGTGGTGCCG

Product: succinate dehydrogenase/fumarate reductase iron-sulfur subunit

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 253; Mature: 252

Protein sequence:

>253_residues
MSHHDKNMTLTLHVWRQKGPKDPGKFEVYEAKDVSPDQSFLEMLDDVNEELIKQGKDPIAFDHDCREGICGMCSQVINGI
PHGGMDRTTVCQLHMRMFKNGDAIYIEPWRARAFPIIKDLVVDRGALDTIIQAGGYTSAHTGGVADGNALLIPKDDADYA
MDAAECIGCGACVAGCPNGSAMLFTSAKVSQLAVLPQGKAEATRRVKAMTETLQECGFGNCTNHYECQAACPKGINVKFI
ATLNREYLKSLCK

Sequences:

>Translated_253_residues
MSHHDKNMTLTLHVWRQKGPKDPGKFEVYEAKDVSPDQSFLEMLDDVNEELIKQGKDPIAFDHDCREGICGMCSQVINGI
PHGGMDRTTVCQLHMRMFKNGDAIYIEPWRARAFPIIKDLVVDRGALDTIIQAGGYTSAHTGGVADGNALLIPKDDADYA
MDAAECIGCGACVAGCPNGSAMLFTSAKVSQLAVLPQGKAEATRRVKAMTETLQECGFGNCTNHYECQAACPKGINVKFI
ATLNREYLKSLCK
>Mature_252_residues
SHHDKNMTLTLHVWRQKGPKDPGKFEVYEAKDVSPDQSFLEMLDDVNEELIKQGKDPIAFDHDCREGICGMCSQVINGIP
HGGMDRTTVCQLHMRMFKNGDAIYIEPWRARAFPIIKDLVVDRGALDTIIQAGGYTSAHTGGVADGNALLIPKDDADYAM
DAAECIGCGACVAGCPNGSAMLFTSAKVSQLAVLPQGKAEATRRVKAMTETLQECGFGNCTNHYECQAACPKGINVKFIA
TLNREYLKSLCK

Specific function: Two Distinct, Membrane-Bound, FAD-Containing Enzymes Are Responsible For The Catalysis Of Fumarate And Succinate Interconversion; The Fumarate Reductase Is Used In Anaerobic Growth, And The Succinate Dehydrogenase Is Used In Aerobic Growth. [C]

COG id: COG0479

COG function: function code C; Succinate dehydrogenase/fumarate reductase, Fe-S protein subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 4Fe-4S ferredoxin-type domain [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR017896
- InterPro:   IPR017900
- InterPro:   IPR012675
- InterPro:   IPR001041
- InterPro:   IPR012285
- InterPro:   IPR009051
- InterPro:   IPR004489 [H]

Pfam domain/function: NA

EC number: =1.3.99.1 [H]

Molecular weight: Translated: 27590; Mature: 27459

Theoretical pI: Translated: 6.30; Mature: 6.30

Prosite motif: PS00197 2FE2S_FER_1 ; PS00198 4FE4S_FERREDOXIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

5.1 %Cys     (Translated Protein)
4.0 %Met     (Translated Protein)
9.1 %Cys+Met (Translated Protein)
5.2 %Cys     (Mature Protein)
3.6 %Met     (Mature Protein)
8.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSHHDKNMTLTLHVWRQKGPKDPGKFEVYEAKDVSPDQSFLEMLDDVNEELIKQGKDPIA
CCCCCCCCEEEEEEEECCCCCCCCCEEEEECCCCCCCHHHHHHHHHHHHHHHHCCCCCCC
FDHDCREGICGMCSQVINGIPHGGMDRTTVCQLHMRMFKNGDAIYIEPWRARAFPIIKDL
CCCHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHCCCCEEEEECCCCCHHHHHHHH
VVDRGALDTIIQAGGYTSAHTGGVADGNALLIPKDDADYAMDAAECIGCGACVAGCPNGS
HHCCCHHHHHHHCCCCCCCCCCCCCCCCEEEEECCCCCHHHHHHHHHCCCHHHCCCCCCC
AMLFTSAKVSQLAVLPQGKAEATRRVKAMTETLQECGFGNCTNHYECQAACPKGINVKFI
EEEEECCCHHHEEECCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCEEHCCCCCCCCEEEE
ATLNREYLKSLCK
EECCHHHHHHHCC
>Mature Secondary Structure 
SHHDKNMTLTLHVWRQKGPKDPGKFEVYEAKDVSPDQSFLEMLDDVNEELIKQGKDPIA
CCCCCCCEEEEEEEECCCCCCCCCEEEEECCCCCCCHHHHHHHHHHHHHHHHCCCCCCC
FDHDCREGICGMCSQVINGIPHGGMDRTTVCQLHMRMFKNGDAIYIEPWRARAFPIIKDL
CCCHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHCCCCEEEEECCCCCHHHHHHHH
VVDRGALDTIIQAGGYTSAHTGGVADGNALLIPKDDADYAMDAAECIGCGACVAGCPNGS
HHCCCHHHHHHHCCCCCCCCCCCCCCCCEEEEECCCCCHHHHHHHHHCCCHHHCCCCCCC
AMLFTSAKVSQLAVLPQGKAEATRRVKAMTETLQECGFGNCTNHYECQAACPKGINVKFI
EEEEECCCHHHEEECCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCEEHCCCCCCCCEEEE
ATLNREYLKSLCK
EECCHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 3027051; 8969504; 9384377; 3114423 [H]