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The map label for this gene is cph1 [H]

Identifier: 39996250

GI number: 39996250

Start: 1239159

End: 1240973

Strand: Direct

Name: cph1 [H]

Synonym: GSU1148

Alternate gene names: 39996250

Gene position: 1239159-1240973 (Clockwise)

Preceding gene: 39996249

Following gene: 39996251

Centisome position: 32.49

GC content: 58.84

Gene sequence:

>1815_bases
ATGATCGACCAGGAGTTCGTGGCGCTCGGCACGGTTGCGGACACCAAAAAGATCCTGATCGAGTCGTGGCTCAAGGAGCG
CCGGAGCGATGCCAGGATCGTTGCGGTCAATCCGGTGGTCAGGGCACTCATCAATATCCCAAACCCCTCTGCTGCGATGA
CTAAAACGGTGTCGACCTGGCTGGCGAGCCTGCTCGACACGTACCAGTATGAGTCGATCAGCATCGTTGATGCCGTGACC
GGACTTCCGATCGCCTCTGCGGGGAATCATCCCCCAGGCCCTGTTACTCCTTATTCTTACCTTCAGACTGCTGCCCGTCC
CGGAGTTGATGAGAGCATCATAATTGTCGGCACTCAGGATCGCATTCACGTGGTACGCCAGCTTGGCTACGAGCAGTCCG
ACCACGGGGAGCCGCGGGCGCTCCTTGTTATCGAGCTGAACACGGACGCAGTGTTCAAGCCGATCCTCGCTACCCCTATG
GCGACCCTGCTCGGCAAATCATGGGAGGTGATCCTGGCCGATTCTGCTTCAGGCCGTCTTATCCAGCGCATGGCCGCTGA
CTCGGATTCGCCGGTGCCGGCAACGATTCGGGATAATGCCCTGCAACTGGCCCAGGGTGGGAGCGAGGGAACCATTATCG
ACACCGATTACCGGAACGTTCCGGTTCTTGCCGCCTACCGCCACATACCACTGTCGGCAGACAGTTCCTGGGGGCTCGTC
ATCAAAAAGGACAAAGCCGAAGTCCTTGCCCCGGCCCACAGAAACCGTCAGGTGTTTCTGTGGTTCAGCTTGTTCGGCAT
CTTCATAGTGTGCCTTATCTCGCTGATTATTTCGCGGGCATTGACGGGGCCGCTGCGAATGATCATGAGCACGAGCGCGG
AGATCGAAAGCGGCAACCTGTCGGCCCGGGTACCTGTTCTTGGGTCGGACGAACTGGCCGACCTCGGCCGAACCTTCAAT
GCCATGGTTGACCAACTCCAGGCCTGGCATGAAGAACTGGACGCGAGGGTTCTTGTCCAGACAGAGGAAATCAGGGCAAT
AAATGAAGATCTCGAGCGCCGTGTCGCTGCAAGGACGGAAGAGCTGCAGGCAGCCCTCAAGGATATGGAGTCGTTTTCCT
ATAGCATTTCCCATGACCTGCGCGCCCCATTGCGGGCCATCGACGGGTTTTGCGGGATCCTGAATGAAGAGTTCCGGGAG
CGGTTGCCGGAAGAGGCCGGGAAGTACCTTGTCCGCATGTCTCACAATGCCCGACGCATGGGGCAGCTCATAGACGACCT
GCTGGCCTTTTCGCGTCTTTCGCGCCAGCCGCTCGAGCGTGAAACGGTTGATATGGGTCTGCTGTTCAGAGAGGTGTTCG
AGTCGCTGATGTCCGATGGAGAACCGCGAAACGTTGTGTTCGAGGTGGCGCCGCTGCCGCAGTGCCAAGCCGACCCCAAG
CTGTTGAGGCAAGTGGTAATCAATCTGCTGAGTAATGCTCTTAAGTTCAGCGGGGGGCGCTCACCGGCGAACATTGCGGT
GACCAGCCGCAGTGTGGATGGCGAGACGGTCTACTCGGTGACCGACAATGGCGTCGGTTTTGATCATGCCTACGCGGATA
AACTGTTCGGCGTCTTCCAGCGCTATCACAAGAGCGAGGAGTTTGAGGGGACCGGCGTGGGGCTCGCCATCGTCCACAAC
ATTATTCAACGTCACGGGGGACGGGTATGGGCGGAGTCGGAACCCGGCAAGGGAGCGACCTTTTCCTTTACGATTGGTAG
TGAAGTGAGTGGGGAAGCGGCACCCGGGTGGAGCGGAGACGGGCGCACGGCATAA

Upstream 100 bases:

>100_bases
CCTCATTTTCTGTTCCCTGTTCGCGGTTGTGTTGCTGGCGGTACAGTCGGTAGAGTTGTATGGGCTTCCGTACGGTCTGT
TCAAGGGGAGCATTGAGGAA

Downstream 100 bases:

>100_bases
GGTGCCTTGATGTTTCGTCGATAAAGGGTTAAGCTTGGCCCAAGCACGGCGTATACATGGTGGAGTGAACATATGGCGGA
AGAAAAGTTTTTTCTGGGCA

Product: sensor histidine kinase

Products: NA

Alternate protein names: Bacteriophytochrome cph1; Light-regulated histidine kinase 1 [H]

Number of amino acids: Translated: 604; Mature: 604

Protein sequence:

>604_residues
MIDQEFVALGTVADTKKILIESWLKERRSDARIVAVNPVVRALINIPNPSAAMTKTVSTWLASLLDTYQYESISIVDAVT
GLPIASAGNHPPGPVTPYSYLQTAARPGVDESIIIVGTQDRIHVVRQLGYEQSDHGEPRALLVIELNTDAVFKPILATPM
ATLLGKSWEVILADSASGRLIQRMAADSDSPVPATIRDNALQLAQGGSEGTIIDTDYRNVPVLAAYRHIPLSADSSWGLV
IKKDKAEVLAPAHRNRQVFLWFSLFGIFIVCLISLIISRALTGPLRMIMSTSAEIESGNLSARVPVLGSDELADLGRTFN
AMVDQLQAWHEELDARVLVQTEEIRAINEDLERRVAARTEELQAALKDMESFSYSISHDLRAPLRAIDGFCGILNEEFRE
RLPEEAGKYLVRMSHNARRMGQLIDDLLAFSRLSRQPLERETVDMGLLFREVFESLMSDGEPRNVVFEVAPLPQCQADPK
LLRQVVINLLSNALKFSGGRSPANIAVTSRSVDGETVYSVTDNGVGFDHAYADKLFGVFQRYHKSEEFEGTGVGLAIVHN
IIQRHGGRVWAESEPGKGATFSFTIGSEVSGEAAPGWSGDGRTA

Sequences:

>Translated_604_residues
MIDQEFVALGTVADTKKILIESWLKERRSDARIVAVNPVVRALINIPNPSAAMTKTVSTWLASLLDTYQYESISIVDAVT
GLPIASAGNHPPGPVTPYSYLQTAARPGVDESIIIVGTQDRIHVVRQLGYEQSDHGEPRALLVIELNTDAVFKPILATPM
ATLLGKSWEVILADSASGRLIQRMAADSDSPVPATIRDNALQLAQGGSEGTIIDTDYRNVPVLAAYRHIPLSADSSWGLV
IKKDKAEVLAPAHRNRQVFLWFSLFGIFIVCLISLIISRALTGPLRMIMSTSAEIESGNLSARVPVLGSDELADLGRTFN
AMVDQLQAWHEELDARVLVQTEEIRAINEDLERRVAARTEELQAALKDMESFSYSISHDLRAPLRAIDGFCGILNEEFRE
RLPEEAGKYLVRMSHNARRMGQLIDDLLAFSRLSRQPLERETVDMGLLFREVFESLMSDGEPRNVVFEVAPLPQCQADPK
LLRQVVINLLSNALKFSGGRSPANIAVTSRSVDGETVYSVTDNGVGFDHAYADKLFGVFQRYHKSEEFEGTGVGLAIVHN
IIQRHGGRVWAESEPGKGATFSFTIGSEVSGEAAPGWSGDGRTA
>Mature_604_residues
MIDQEFVALGTVADTKKILIESWLKERRSDARIVAVNPVVRALINIPNPSAAMTKTVSTWLASLLDTYQYESISIVDAVT
GLPIASAGNHPPGPVTPYSYLQTAARPGVDESIIIVGTQDRIHVVRQLGYEQSDHGEPRALLVIELNTDAVFKPILATPM
ATLLGKSWEVILADSASGRLIQRMAADSDSPVPATIRDNALQLAQGGSEGTIIDTDYRNVPVLAAYRHIPLSADSSWGLV
IKKDKAEVLAPAHRNRQVFLWFSLFGIFIVCLISLIISRALTGPLRMIMSTSAEIESGNLSARVPVLGSDELADLGRTFN
AMVDQLQAWHEELDARVLVQTEEIRAINEDLERRVAARTEELQAALKDMESFSYSISHDLRAPLRAIDGFCGILNEEFRE
RLPEEAGKYLVRMSHNARRMGQLIDDLLAFSRLSRQPLERETVDMGLLFREVFESLMSDGEPRNVVFEVAPLPQCQADPK
LLRQVVINLLSNALKFSGGRSPANIAVTSRSVDGETVYSVTDNGVGFDHAYADKLFGVFQRYHKSEEFEGTGVGLAIVHN
IIQRHGGRVWAESEPGKGATFSFTIGSEVSGEAAPGWSGDGRTA

Specific function: Regulatory photoreceptor which exists in two forms that are reversibly interconvertible by light:the R form that absorbs maximally in the red region of the spectrum and the FR form that absorbs maximally in the far-red region. Has also a slight blue shift

COG id: COG0642

COG function: function code T; Signal transduction histidine kinase

Gene ontology:

Cell location: Integral Membrane Protein. Inner Membrane [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PAS (PER-ARNT-SIM) domain [H]

Homologues:

Organism=Escherichia coli, GI1789149, Length=357, Percent_Identity=26.890756302521, Blast_Score=111, Evalue=1e-25,
Organism=Escherichia coli, GI1790436, Length=242, Percent_Identity=32.2314049586777, Blast_Score=107, Evalue=2e-24,
Organism=Escherichia coli, GI48994928, Length=234, Percent_Identity=30.3418803418803, Blast_Score=102, Evalue=1e-22,
Organism=Escherichia coli, GI1788549, Length=216, Percent_Identity=31.0185185185185, Blast_Score=89, Evalue=6e-19,
Organism=Escherichia coli, GI1786600, Length=237, Percent_Identity=30.379746835443, Blast_Score=87, Evalue=4e-18,
Organism=Escherichia coli, GI87081816, Length=352, Percent_Identity=28.9772727272727, Blast_Score=87, Evalue=4e-18,
Organism=Escherichia coli, GI145693157, Length=267, Percent_Identity=29.2134831460674, Blast_Score=85, Evalue=2e-17,
Organism=Escherichia coli, GI1790346, Length=304, Percent_Identity=29.9342105263158, Blast_Score=82, Evalue=1e-16,
Organism=Escherichia coli, GI1786912, Length=253, Percent_Identity=30.0395256916996, Blast_Score=79, Evalue=6e-16,
Organism=Escherichia coli, GI1790861, Length=224, Percent_Identity=29.9107142857143, Blast_Score=79, Evalue=7e-16,
Organism=Escherichia coli, GI1788713, Length=232, Percent_Identity=25.8620689655172, Blast_Score=75, Evalue=2e-14,
Organism=Escherichia coli, GI1786783, Length=260, Percent_Identity=26.9230769230769, Blast_Score=73, Evalue=6e-14,
Organism=Escherichia coli, GI1788393, Length=318, Percent_Identity=22.9559748427673, Blast_Score=70, Evalue=3e-13,
Organism=Escherichia coli, GI87082128, Length=337, Percent_Identity=23.1454005934718, Blast_Score=65, Evalue=1e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR003018
- InterPro:   IPR000014
- InterPro:   IPR013654
- InterPro:   IPR016132
- InterPro:   IPR001294
- InterPro:   IPR013515
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR009082 [H]

Pfam domain/function: PF01590 GAF; PF02518 HATPase_c; PF00512 HisKA; PF08446 PAS_2; PF00360 Phytochrome [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 66197; Mature: 66197

Theoretical pI: Translated: 5.06; Mature: 5.06

Prosite motif: PS00012 PHOSPHOPANTETHEINE ; PS50885 HAMP ; PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIDQEFVALGTVADTKKILIESWLKERRSDARIVAVNPVVRALINIPNPSAAMTKTVSTW
CCCCHHEEECCHHHHHHHHHHHHHHHHCCCCEEEEECHHHHHHHCCCCCHHHHHHHHHHH
LASLLDTYQYESISIVDAVTGLPIASAGNHPPGPVTPYSYLQTAARPGVDESIIIVGTQD
HHHHHHHHCCCCEEHHHHHHCCCCCCCCCCCCCCCCHHHHHHHHHCCCCCCCEEEEECCH
RIHVVRQLGYEQSDHGEPRALLVIELNTDAVFKPILATPMATLLGKSWEVILADSASGRL
HHHHHHHHCCCCCCCCCCEEEEEEEECCCHHHHHHHHHHHHHHHCCCCEEEEECCCCCHH
IQRMAADSDSPVPATIRDNALQLAQGGSEGTIIDTDYRNVPVLAAYRHIPLSADSSWGLV
HHHHHCCCCCCCCCHHHCCHHHHHCCCCCCCEEECCCCCCCEEEHEEECCCCCCCCCCEE
IKKDKAEVLAPAHRNRQVFLWFSLFGIFIVCLISLIISRALTGPLRMIMSTSAEIESGNL
EECCCHHHHCCCCCCCEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCC
SARVPVLGSDELADLGRTFNAMVDQLQAWHEELDARVLVQTEEIRAINEDLERRVAARTE
EEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEHHHHHHHHHHHHHHHHHHHH
ELQAALKDMESFSYSISHDLRAPLRAIDGFCGILNEEFRERLPEEAGKYLVRMSHNARRM
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHCCCHHHH
GQLIDDLLAFSRLSRQPLERETVDMGLLFREVFESLMSDGEPRNVVFEVAPLPQCQADPK
HHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEECCCCCCCCCHH
LLRQVVINLLSNALKFSGGRSPANIAVTSRSVDGETVYSVTDNGVGFDHAYADKLFGVFQ
HHHHHHHHHHHHHHHCCCCCCCCEEEEEECCCCCCEEEEEECCCCCCCHHHHHHHHHHHH
RYHKSEEFEGTGVGLAIVHNIIQRHGGRVWAESEPGKGATFSFTIGSEVSGEAAPGWSGD
HHHCCCCCCCCCCHHHHHHHHHHHCCCEEEECCCCCCCCEEEEEECCCCCCCCCCCCCCC
GRTA
CCCC
>Mature Secondary Structure
MIDQEFVALGTVADTKKILIESWLKERRSDARIVAVNPVVRALINIPNPSAAMTKTVSTW
CCCCHHEEECCHHHHHHHHHHHHHHHHCCCCEEEEECHHHHHHHCCCCCHHHHHHHHHHH
LASLLDTYQYESISIVDAVTGLPIASAGNHPPGPVTPYSYLQTAARPGVDESIIIVGTQD
HHHHHHHHCCCCEEHHHHHHCCCCCCCCCCCCCCCCHHHHHHHHHCCCCCCCEEEEECCH
RIHVVRQLGYEQSDHGEPRALLVIELNTDAVFKPILATPMATLLGKSWEVILADSASGRL
HHHHHHHHCCCCCCCCCCEEEEEEEECCCHHHHHHHHHHHHHHHCCCCEEEEECCCCCHH
IQRMAADSDSPVPATIRDNALQLAQGGSEGTIIDTDYRNVPVLAAYRHIPLSADSSWGLV
HHHHHCCCCCCCCCHHHCCHHHHHCCCCCCCEEECCCCCCCEEEHEEECCCCCCCCCCEE
IKKDKAEVLAPAHRNRQVFLWFSLFGIFIVCLISLIISRALTGPLRMIMSTSAEIESGNL
EECCCHHHHCCCCCCCEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCC
SARVPVLGSDELADLGRTFNAMVDQLQAWHEELDARVLVQTEEIRAINEDLERRVAARTE
EEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEHHHHHHHHHHHHHHHHHHHH
ELQAALKDMESFSYSISHDLRAPLRAIDGFCGILNEEFRERLPEEAGKYLVRMSHNARRM
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHCCCHHHH
GQLIDDLLAFSRLSRQPLERETVDMGLLFREVFESLMSDGEPRNVVFEVAPLPQCQADPK
HHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEECCCCCCCCCHH
LLRQVVINLLSNALKFSGGRSPANIAVTSRSVDGETVYSVTDNGVGFDHAYADKLFGVFQ
HHHHHHHHHHHHHHHCCCCCCCCEEEEEECCCCCCEEEEEECCCCCCCHHHHHHHHHHHH
RYHKSEEFEGTGVGLAIVHNIIQRHGGRVWAESEPGKGATFSFTIGSEVSGEAAPGWSGD
HHHCCCCCCCCCCHHHHHHHHHHHCCCEEEECCCCCCCCEEEEEECCCCCCCCCCCCCCC
GRTA
CCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8590279; 8905231; 9109482; 9278513; 10828948 [H]