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The map label for this gene is hlyB [H]

Identifier: 39996135

GI number: 39996135

Start: 1111658

End: 1113595

Strand: Direct

Name: hlyB [H]

Synonym: GSU1032

Alternate gene names: 39996135

Gene position: 1111658-1113595 (Clockwise)

Preceding gene: 39996134

Following gene: 39996136

Centisome position: 29.15

GC content: 64.5

Gene sequence:

>1938_bases
ATGGCAGGGCTTACGGTGCTGGGGCTGGCGGCGGTAACGGCGCTCTCCCTCTATGGGGTCAACCGCCAGGTTGCGGAGAC
CGAGACCATCGTTCAGGTGGACGCAGCCCAGGTGGATGTTGCCCTGAAGTCGCAGGTGAGCCTGGCGGAGGCGGTCCGGG
CCTACAAGAATTACCTGGTGCGCAAGGACGACAAGCATGTGACCGGTTTCCGCGAGAGCATCGGTACCTTTGAGAAAAAC
ATCGCCGAATTCGAGAAACTGGCCAACACCGATGGGGAAAAGGCCGCGGTCGGCAAGGCAAAGGAAGAGCTGGGCAAGTA
CCGGGGATGCATCGATGAACTGGTAGCGGCGCGCGGTGCCAGTGACGATGTGGCCGCCATTGACCGCAATCTTGCCCGGG
GGATTGACCGTCCTCTCGAGGCAGCGGTGAAGGAGATGGAAAAGGCGGCCCGGCAAAGCTTTGGCGATAGCCGTGCCGCC
CTGGCCGCTTCGTCCAAGCGTCTGCTCGTGGGCCAAGCGGTTTTCTCGGTGATCGTGGCCCTGCTGGCTGCCGGCTTCGG
ATTCAATACGGCCCGCCGTTTCGTGTTCCGGCTCGGCAAATTTTCCGAGATGATCGCCCGGGTGGCGGACAGCGACCTGA
CCGCCCGTGTGGTGATCAGGGCCGATGACGAATTGGGTGACATGGGGCGTACGTTCAACCGGATGGTGGAGAATTTCGAA
CACATGCTTACATCGATCCAGAACGCGGTGCTCAACCTTTCGGAGTCTGCCCGCACCCTGAGCGTCACGTCGGAGCAGAT
CGCCACCGGCGCCGAGGAAATGGCCTCCCAGACCGGGACCGTTGCCACTGCCAGCGAGGAAATGGCGGCCACCTCCCAGG
AGATCGCCCAGAACTGTTCGACCGCAGCCGACGTGGCCCGGAATGCGAGTGCCAGTGCCCGGTCCGGCGCGGCTGTGGTG
CAGCAGACCATCGGCGCCATGGAGCGCATCACCGAGCGGGTGCGCGATACCGCCCGAACGGTCGAGGCCCTTGGCGCGCG
CAGCGACCAGATCGGCGAGATTGTCGGCACCATCCAGGATATTGCCGACCAGACCAACCTGCTGGCTCTGAACGCCGCCA
TCGAGGCGGCACGGGCCGGTGAGCAGGGGCGCGGTTTTGCCGTGGTGGCCGACGAGGTGCGCGCCCTGGCCGAGCGGACC
ACCCGGGCAACCCGCGAGATTGCCGAGATGATCAAATCCATCCAGCAGGAAACGCGGGGAGCCGTTGCGTCCATGGAGGA
AGGGGTCGTTGAAGTGACGCAGGGGAGTGCCGATGCGGCCCGCTCCGGAGACGCACTGCGGGAAATTCTCGACCAGATCG
AGCAGGTGACGGGCCAGGTGGCCCAGATCGCCACGGCAGCGGAGCAGCAGACCGCCACCACCAGCGAGATCACCATGAAC
ATCCAGCAGATCACCGAGGTGGTGGGCCATACGGCCCGCGAAGCGGGCGAGAGCGCCGATGCCGCCACCGGGCTGGCAAC
GCTGGCCGATGAACTGCAGACCGAAGTGAGAACGTTCAAGACGTCCGGAAGCGAACTTTTCATTCTGGAACTGGCCAAAA
AGGACCATAGCGGTTTCGTCACCACGGTAGAGGCGGTCCTCGTCGGGCGCCGGCGCATGGAGGCGGGTGAGCTCTCCACC
CACCATACTTGCCGCTTCGGCAAATGGTATGAGGGTGACGGCAGGCAGCTGTGCGGGCACTTGGCCAGCTACAAGGCTAT
CTACGCACCCCACGAGCGGATCCACTCACTGGCCCGTGACGTGGTTGCTGCGGTGAACGGCGGGGACCGAGACCGGGCAG
CCCGCCTCTTCCCCGAGTTGAAAGAGCTGTCACGGGAGATCATTACCCGCCTCGACGATATCCGCCGCGAGTTCGAAGCC
CAACGCGCGGCGGCGTGA

Upstream 100 bases:

>100_bases
GTACGGCAGTGGATACGGTTGGAGCGGCTCATCGTGAAGTTGTGATGGAAGAGGAAGGAGAGGTTCGATGTGAATTTCCA
TTGGTACAAAGTTGTACGGA

Downstream 100 bases:

>100_bases
GCACTGACCCCCCACTAGTCTCCACATCAGGGGCCGGTTTCGACCGGCCCTTTCAGTTTGTCTCTCGGGGTGAACGTATA
CGCCGTCCGGCTCGCGCGGC

Product: methyl-accepting chemotaxis protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 645; Mature: 644

Protein sequence:

>645_residues
MAGLTVLGLAAVTALSLYGVNRQVAETETIVQVDAAQVDVALKSQVSLAEAVRAYKNYLVRKDDKHVTGFRESIGTFEKN
IAEFEKLANTDGEKAAVGKAKEELGKYRGCIDELVAARGASDDVAAIDRNLARGIDRPLEAAVKEMEKAARQSFGDSRAA
LAASSKRLLVGQAVFSVIVALLAAGFGFNTARRFVFRLGKFSEMIARVADSDLTARVVIRADDELGDMGRTFNRMVENFE
HMLTSIQNAVLNLSESARTLSVTSEQIATGAEEMASQTGTVATASEEMAATSQEIAQNCSTAADVARNASASARSGAAVV
QQTIGAMERITERVRDTARTVEALGARSDQIGEIVGTIQDIADQTNLLALNAAIEAARAGEQGRGFAVVADEVRALAERT
TRATREIAEMIKSIQQETRGAVASMEEGVVEVTQGSADAARSGDALREILDQIEQVTGQVAQIATAAEQQTATTSEITMN
IQQITEVVGHTAREAGESADAATGLATLADELQTEVRTFKTSGSELFILELAKKDHSGFVTTVEAVLVGRRRMEAGELST
HHTCRFGKWYEGDGRQLCGHLASYKAIYAPHERIHSLARDVVAAVNGGDRDRAARLFPELKELSREIITRLDDIRREFEA
QRAAA

Sequences:

>Translated_645_residues
MAGLTVLGLAAVTALSLYGVNRQVAETETIVQVDAAQVDVALKSQVSLAEAVRAYKNYLVRKDDKHVTGFRESIGTFEKN
IAEFEKLANTDGEKAAVGKAKEELGKYRGCIDELVAARGASDDVAAIDRNLARGIDRPLEAAVKEMEKAARQSFGDSRAA
LAASSKRLLVGQAVFSVIVALLAAGFGFNTARRFVFRLGKFSEMIARVADSDLTARVVIRADDELGDMGRTFNRMVENFE
HMLTSIQNAVLNLSESARTLSVTSEQIATGAEEMASQTGTVATASEEMAATSQEIAQNCSTAADVARNASASARSGAAVV
QQTIGAMERITERVRDTARTVEALGARSDQIGEIVGTIQDIADQTNLLALNAAIEAARAGEQGRGFAVVADEVRALAERT
TRATREIAEMIKSIQQETRGAVASMEEGVVEVTQGSADAARSGDALREILDQIEQVTGQVAQIATAAEQQTATTSEITMN
IQQITEVVGHTAREAGESADAATGLATLADELQTEVRTFKTSGSELFILELAKKDHSGFVTTVEAVLVGRRRMEAGELST
HHTCRFGKWYEGDGRQLCGHLASYKAIYAPHERIHSLARDVVAAVNGGDRDRAARLFPELKELSREIITRLDDIRREFEA
QRAAA
>Mature_644_residues
AGLTVLGLAAVTALSLYGVNRQVAETETIVQVDAAQVDVALKSQVSLAEAVRAYKNYLVRKDDKHVTGFRESIGTFEKNI
AEFEKLANTDGEKAAVGKAKEELGKYRGCIDELVAARGASDDVAAIDRNLARGIDRPLEAAVKEMEKAARQSFGDSRAAL
AASSKRLLVGQAVFSVIVALLAAGFGFNTARRFVFRLGKFSEMIARVADSDLTARVVIRADDELGDMGRTFNRMVENFEH
MLTSIQNAVLNLSESARTLSVTSEQIATGAEEMASQTGTVATASEEMAATSQEIAQNCSTAADVARNASASARSGAAVVQ
QTIGAMERITERVRDTARTVEALGARSDQIGEIVGTIQDIADQTNLLALNAAIEAARAGEQGRGFAVVADEVRALAERTT
RATREIAEMIKSIQQETRGAVASMEEGVVEVTQGSADAARSGDALREILDQIEQVTGQVAQIATAAEQQTATTSEITMNI
QQITEVVGHTAREAGESADAATGLATLADELQTEVRTFKTSGSELFILELAKKDHSGFVTTVEAVLVGRRRMEAGELSTH
HTCRFGKWYEGDGRQLCGHLASYKAIYAPHERIHSLARDVVAAVNGGDRDRAARLFPELKELSREIITRLDDIRREFEAQ
RAAA

Specific function: May form a pore through which the hemolysin can be exported [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell outer membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 methyl-accepting transducer domain [H]

Homologues:

Organism=Escherichia coli, GI2367378, Length=419, Percent_Identity=27.9236276849642, Blast_Score=137, Evalue=2e-33,
Organism=Escherichia coli, GI1787690, Length=392, Percent_Identity=29.3367346938776, Blast_Score=130, Evalue=2e-31,
Organism=Escherichia coli, GI1788195, Length=308, Percent_Identity=30.5194805194805, Blast_Score=124, Evalue=2e-29,
Organism=Escherichia coli, GI1788194, Length=248, Percent_Identity=34.2741935483871, Blast_Score=116, Evalue=4e-27,
Organism=Escherichia coli, GI1789453, Length=283, Percent_Identity=30.7420494699647, Blast_Score=99, Evalue=1e-21,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004090
- InterPro:   IPR004089
- InterPro:   IPR003660
- InterPro:   IPR000727 [H]

Pfam domain/function: PF00672 HAMP; PF00015 MCPsignal [H]

EC number: NA

Molecular weight: Translated: 69182; Mature: 69051

Theoretical pI: Translated: 4.95; Mature: 4.95

Prosite motif: PS50885 HAMP ; PS50111 CHEMOTAXIS_TRANSDUC_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAGLTVLGLAAVTALSLYGVNRQVAETETIVQVDAAQVDVALKSQVSLAEAVRAYKNYLV
CCCHHHHHHHHHHHHHHHCCCCHHHHHHHHHEEHHHHHHHHHHHHHHHHHHHHHHHHHHH
RKDDKHVTGFRESIGTFEKNIAEFEKLANTDGEKAAVGKAKEELGKYRGCIDELVAARGA
CCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCC
SDDVAAIDRNLARGIDRPLEAAVKEMEKAARQSFGDSRAALAASSKRLLVGQAVFSVIVA
CCHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHCCCCHHHHHHHCCCHHHHHHHHHHHHHH
LLAAGFGFNTARRFVFRLGKFSEMIARVADSDLTARVVIRADDELGDMGRTFNRMVENFE
HHHCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEEECCHHHHHHHHHHHHHHHHH
HMLTSIQNAVLNLSESARTLSVTSEQIATGAEEMASQTGTVATASEEMAATSQEIAQNCS
HHHHHHHHHHHHHHHCHHHHHHHHHHHHCCHHHHHHCCCCCEECHHHHHHHHHHHHHHHH
TAADVARNASASARSGAAVVQQTIGAMERITERVRDTARTVEALGARSDQIGEIVGTIQD
HHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHH
IADQTNLLALNAAIEAARAGEQGRGFAVVADEVRALAERTTRATREIAEMIKSIQQETRG
HHCCHHEEHHHHHHHHHHCCCCCCCEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AVASMEEGVVEVTQGSADAARSGDALREILDQIEQVTGQVAQIATAAEQQTATTSEITMN
HHHHHHCCCCEECCCCCHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHH
IQQITEVVGHTAREAGESADAATGLATLADELQTEVRTFKTSGSELFILELAKKDHSGFV
HHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEECCCCCCCHH
TTVEAVLVGRRRMEAGELSTHHTCRFGKWYEGDGRQLCGHLASYKAIYAPHERIHSLARD
HHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCHHHHHHHHHH
VVAAVNGGDRDRAARLFPELKELSREIITRLDDIRREFEAQRAAA
HHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure 
AGLTVLGLAAVTALSLYGVNRQVAETETIVQVDAAQVDVALKSQVSLAEAVRAYKNYLV
CCHHHHHHHHHHHHHHHCCCCHHHHHHHHHEEHHHHHHHHHHHHHHHHHHHHHHHHHHH
RKDDKHVTGFRESIGTFEKNIAEFEKLANTDGEKAAVGKAKEELGKYRGCIDELVAARGA
CCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCC
SDDVAAIDRNLARGIDRPLEAAVKEMEKAARQSFGDSRAALAASSKRLLVGQAVFSVIVA
CCHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHCCCCHHHHHHHCCCHHHHHHHHHHHHHH
LLAAGFGFNTARRFVFRLGKFSEMIARVADSDLTARVVIRADDELGDMGRTFNRMVENFE
HHHCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEEECCHHHHHHHHHHHHHHHHH
HMLTSIQNAVLNLSESARTLSVTSEQIATGAEEMASQTGTVATASEEMAATSQEIAQNCS
HHHHHHHHHHHHHHHCHHHHHHHHHHHHCCHHHHHHCCCCCEECHHHHHHHHHHHHHHHH
TAADVARNASASARSGAAVVQQTIGAMERITERVRDTARTVEALGARSDQIGEIVGTIQD
HHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHH
IADQTNLLALNAAIEAARAGEQGRGFAVVADEVRALAERTTRATREIAEMIKSIQQETRG
HHCCHHEEHHHHHHHHHHCCCCCCCEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AVASMEEGVVEVTQGSADAARSGDALREILDQIEQVTGQVAQIATAAEQQTATTSEITMN
HHHHHHCCCCEECCCCCHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHH
IQQITEVVGHTAREAGESADAATGLATLADELQTEVRTFKTSGSELFILELAKKDHSGFV
HHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEECCCCCCCHH
TTVEAVLVGRRRMEAGELSTHHTCRFGKWYEGDGRQLCGHLASYKAIYAPHERIHSLARD
HHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCHHHHHHHHHH
VVAAVNGGDRDRAARLFPELKELSREIITRLDDIRREFEAQRAAA
HHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 2162464; 10952301 [H]