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The map label for this gene is yicO [C]

Identifier: 39996122

GI number: 39996122

Start: 1100288

End: 1101589

Strand: Direct

Name: yicO [C]

Synonym: GSU1019

Alternate gene names: 39996122

Gene position: 1100288-1101589 (Clockwise)

Preceding gene: 39996120

Following gene: 39996123

Centisome position: 28.85

GC content: 60.68

Gene sequence:

>1302_bases
ATGAAACATTTTTTTCAGTTCGAGCGCTACAACACCACCTACCGCAAGGAGACGGTGGCGGGCATTACCACCTTCCTGAC
CATGGCGTACATCATCATCGTCAATCCCGCCATCCTCGAGGCGGCGGGGATTCCGCGGGGCCCCTCCACAACGGCCACCA
TCGTGGCCGCGGTCTTCGGCACGGTAGTGATGGCGTTGTACGCCAACCGCCCCTTTGCCATTGCTCCGTACATGAGCGAG
AACGCCTTTATCGCCTTCACCGTGGTCAAGGTGCTGGGATATTCATGGCAGACAGCCCTGGGAGCGGTCTTCGTGGCGGG
CGTACTGTTCACGGTCCTGACCGTTTTCAAAGTGCGGAGCTGGCTGGCCGAGGCGATCCCGCTCTCGCTCAAATGCGCTT
TTGCCGTCGGTATTGGACTGTTTCTCACCTTCATCGGCCTGAACGAAACCGGTCTCGTTACCCTCGGCGTGCCGGGGGCG
CCGGTCAAGATGGGTAACATCGCCTCTCCGTCGGTGCTTCTGGCGGTCTTCGGCTACCTCCTCACTGTCTTTCTCATGAC
GCGCAAGATTCACGGGGCCATTGTGATCGGCATCGTCGCCACCACCGTCCTGTCGGTGGCCTGCGGGGTGACGCCCATGC
CGACCGAATTCGTGAGCATGCCGCCGGATCTCTCGCCGATCCTGTTTCAGCTCAACATCGGTGATGCCCTCGACATCCGC
TTCTTCCCCGTGGTCCTCACCATCTTCATAATGGCGTTCCTCGATACGGTGGGCACCCTCATCGGCCTCTCCATGCGGGC
CGATCTGCTGGATGAGAAGGGGAACCTGCCGGAGATCGAGAAACCGATGCTGGCCGATGCCCTTGCCACCACCGTGGCGC
CGTTGCTGGGCACCACTACTACCGGCGCCTACATCGAATCGGCCACCGGCATCGAAGAAGGGGGGCGCACCGGCTTCACG
GCACTGGTGGTGGCGGGGCTCTTCCTGATGTCCCTCTTTTTCGCGCCGCTGTTCACCATTGTGCCTCCCCATGCTTACGG
TATCGCCCTCATCGTGATCGGTTCCTTCATGATCGAGCCGCTCCGCCGGATCGACTTCGAGGACTTCACCGAGCTGGTTC
CCGCTTTCCTTACCATCGTGCTGATGATTTTCACCTACAACATCGGCGTCGGCATGAGCACGGGGCTGCTTACCTATCCC
CTCCTCAAGACCGCCGCCGGCAAGAGACACCAGGTCTCTGCTGGTATGTGGGTCCTGGCGGGGCTTGCGGTGCTGCTGTT
CGTCTTTTTCCCCAAGATGTAA

Upstream 100 bases:

>100_bases
GGCAGCACAGTTTTGCTGTGAGCGGCGTCACAGAACAAGGGGCTGCCCCCTGGTACCCTGAGCGCCGTCCGAAACTCATA
TCCATTTTTCTGAGGCGTCC

Downstream 100 bases:

>100_bases
GCTGTAAGCGCGTCGGACTTCCGACGCAAAAAGGCCCGCACATGGTGGCGGGCCTTTTTGCGTCGGGGCGGGAAACCTTA
GCCGTGCTCGACCGTCACGG

Product: xanthine/uracil permease

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 433; Mature: 433

Protein sequence:

>433_residues
MKHFFQFERYNTTYRKETVAGITTFLTMAYIIIVNPAILEAAGIPRGPSTTATIVAAVFGTVVMALYANRPFAIAPYMSE
NAFIAFTVVKVLGYSWQTALGAVFVAGVLFTVLTVFKVRSWLAEAIPLSLKCAFAVGIGLFLTFIGLNETGLVTLGVPGA
PVKMGNIASPSVLLAVFGYLLTVFLMTRKIHGAIVIGIVATTVLSVACGVTPMPTEFVSMPPDLSPILFQLNIGDALDIR
FFPVVLTIFIMAFLDTVGTLIGLSMRADLLDEKGNLPEIEKPMLADALATTVAPLLGTTTTGAYIESATGIEEGGRTGFT
ALVVAGLFLMSLFFAPLFTIVPPHAYGIALIVIGSFMIEPLRRIDFEDFTELVPAFLTIVLMIFTYNIGVGMSTGLLTYP
LLKTAAGKRHQVSAGMWVLAGLAVLLFVFFPKM

Sequences:

>Translated_433_residues
MKHFFQFERYNTTYRKETVAGITTFLTMAYIIIVNPAILEAAGIPRGPSTTATIVAAVFGTVVMALYANRPFAIAPYMSE
NAFIAFTVVKVLGYSWQTALGAVFVAGVLFTVLTVFKVRSWLAEAIPLSLKCAFAVGIGLFLTFIGLNETGLVTLGVPGA
PVKMGNIASPSVLLAVFGYLLTVFLMTRKIHGAIVIGIVATTVLSVACGVTPMPTEFVSMPPDLSPILFQLNIGDALDIR
FFPVVLTIFIMAFLDTVGTLIGLSMRADLLDEKGNLPEIEKPMLADALATTVAPLLGTTTTGAYIESATGIEEGGRTGFT
ALVVAGLFLMSLFFAPLFTIVPPHAYGIALIVIGSFMIEPLRRIDFEDFTELVPAFLTIVLMIFTYNIGVGMSTGLLTYP
LLKTAAGKRHQVSAGMWVLAGLAVLLFVFFPKM
>Mature_433_residues
MKHFFQFERYNTTYRKETVAGITTFLTMAYIIIVNPAILEAAGIPRGPSTTATIVAAVFGTVVMALYANRPFAIAPYMSE
NAFIAFTVVKVLGYSWQTALGAVFVAGVLFTVLTVFKVRSWLAEAIPLSLKCAFAVGIGLFLTFIGLNETGLVTLGVPGA
PVKMGNIASPSVLLAVFGYLLTVFLMTRKIHGAIVIGIVATTVLSVACGVTPMPTEFVSMPPDLSPILFQLNIGDALDIR
FFPVVLTIFIMAFLDTVGTLIGLSMRADLLDEKGNLPEIEKPMLADALATTVAPLLGTTTTGAYIESATGIEEGGRTGFT
ALVVAGLFLMSLFFAPLFTIVPPHAYGIALIVIGSFMIEPLRRIDFEDFTELVPAFLTIVLMIFTYNIGVGMSTGLLTYP
LLKTAAGKRHQVSAGMWVLAGLAVLLFVFFPKM

Specific function: Unknown

COG id: COG2252

COG function: function code R; Permeases

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the xanthine/uracil permease family. AzgA purine transporter (TC 2.A.1.40) subfamily [H]

Homologues:

Organism=Escherichia coli, GI87082309, Length=426, Percent_Identity=38.2629107981221, Blast_Score=308, Evalue=3e-85,
Organism=Escherichia coli, GI1790150, Length=429, Percent_Identity=37.7622377622378, Blast_Score=296, Evalue=1e-81,
Organism=Escherichia coli, GI1790499, Length=428, Percent_Identity=34.1121495327103, Blast_Score=226, Evalue=2e-60,
Organism=Escherichia coli, GI48994909, Length=420, Percent_Identity=33.0952380952381, Blast_Score=213, Evalue=2e-56,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006043 [H]

Pfam domain/function: PF00860 Xan_ur_permease [H]

EC number: NA

Molecular weight: Translated: 46415; Mature: 46415

Theoretical pI: Translated: 6.95; Mature: 6.95

Prosite motif: PS00211 ABC_TRANSPORTER_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
3.9 %Met     (Translated Protein)
4.4 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
3.9 %Met     (Mature Protein)
4.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKHFFQFERYNTTYRKETVAGITTFLTMAYIIIVNPAILEAAGIPRGPSTTATIVAAVFG
CCCCHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHCHHHHHHCCCCCCCCHHHHHHHHHHH
TVVMALYANRPFAIAPYMSENAFIAFTVVKVLGYSWQTALGAVFVAGVLFTVLTVFKVRS
HHHHHHHCCCCEEEECCCCCCCCHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHH
WLAEAIPLSLKCAFAVGIGLFLTFIGLNETGLVTLGVPGAPVKMGNIASPSVLLAVFGYL
HHHHHCCHHHHHHHHHHHHHHHHHHCCCCCCEEEECCCCCCEECCCCCCHHHHHHHHHHH
LTVFLMTRKIHGAIVIGIVATTVLSVACGVTPMPTEFVSMPPDLSPILFQLNIGDALDIR
HHHHHHHHHHCCHHHHHHHHHHHHHHHHCCCCCCHHHHCCCCCCCCEEEEEECCCCCHHH
FFPVVLTIFIMAFLDTVGTLIGLSMRADLLDEKGNLPEIEKPMLADALATTVAPLLGTTT
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHCCCC
TGAYIESATGIEEGGRTGFTALVVAGLFLMSLFFAPLFTIVPPHAYGIALIVIGSFMIEP
CCHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHH
LRRIDFEDFTELVPAFLTIVLMIFTYNIGVGMSTGLLTYPLLKTAAGKRHQVSAGMWVLA
HHHCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHCCCCCCCHHHHHHHHH
GLAVLLFVFFPKM
HHHHHHHHHHCCC
>Mature Secondary Structure
MKHFFQFERYNTTYRKETVAGITTFLTMAYIIIVNPAILEAAGIPRGPSTTATIVAAVFG
CCCCHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHCHHHHHHCCCCCCCCHHHHHHHHHHH
TVVMALYANRPFAIAPYMSENAFIAFTVVKVLGYSWQTALGAVFVAGVLFTVLTVFKVRS
HHHHHHHCCCCEEEECCCCCCCCHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHH
WLAEAIPLSLKCAFAVGIGLFLTFIGLNETGLVTLGVPGAPVKMGNIASPSVLLAVFGYL
HHHHHCCHHHHHHHHHHHHHHHHHHCCCCCCEEEECCCCCCEECCCCCCHHHHHHHHHHH
LTVFLMTRKIHGAIVIGIVATTVLSVACGVTPMPTEFVSMPPDLSPILFQLNIGDALDIR
HHHHHHHHHHCCHHHHHHHHHHHHHHHHCCCCCCHHHHCCCCCCCCEEEEEECCCCCHHH
FFPVVLTIFIMAFLDTVGTLIGLSMRADLLDEKGNLPEIEKPMLADALATTVAPLLGTTT
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHCCCC
TGAYIESATGIEEGGRTGFTALVVAGLFLMSLFFAPLFTIVPPHAYGIALIVIGSFMIEP
CCHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHH
LRRIDFEDFTELVPAFLTIVLMIFTYNIGVGMSTGLLTYPLLKTAAGKRHQVSAGMWVLA
HHHCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHCCCCCCCHHHHHHHHH
GLAVLLFVFFPKM
HHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8688087 [H]