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The map label for this gene is btuB [H]

Identifier: 39995989

GI number: 39995989

Start: 942296

End: 944179

Strand: Reverse

Name: btuB [H]

Synonym: GSU0883

Alternate gene names: 39995989

Gene position: 944179-942296 (Counterclockwise)

Preceding gene: 39995991

Following gene: 39995988

Centisome position: 24.75

GC content: 59.29

Gene sequence:

>1884_bases
ATGCCAACTGCGAGCCCTATCAACACTGCGAAATCGCGCGCCGGAAGCACCTTTCGGCGCCTTTCGTCGTTGCTTCCGGG
GCTCTTTTTTTTCTTGGGTCTCCTCGCCCTGACCTTACCCTTCACGGCCCACGCCGAAACCGACAGCGACCGAGAACTCC
TGGAACTCTACTACGAGCCCCAGGACCTGACCGTCTCCACCGCCACCCGCTCCCCCCGGCCACTTTCGCGGAGTGCTGAA
AACATCACGGTCATCACTGCCGAGCAGATAGAAGCGATGAACGCCCACACTCTGGCCGACGTGCTAGCTACGGTTCCCGG
TGTTCAGGTCTCCGGCAATACTGCTCCGGCATCCATCACCTTCACTGAATTCGCAGGCGCCACCACCCGATACATCCAGA
TTTTGGTCGATGGAGTTCCCATTGACGATCAGTTCGACAACTTTGCCGCCCCAGGCATGGTTCCGGTCCAGATCATCGAG
CGGGTGGAGGTACTCAAGGGGCCTGCCTCCTCAAGCTGGGGCAACTCACTGGGGGGGATCGTCAACGTCATCACCAAGGA
ACCGGCCCTCCACGCCTCCTTCAGCGGCGCCGCTTCCTTCTCGGGCGGCGAGAACGGCACCCGTGACGGCCGGGGCGAAG
TCTCCGGTACGGTGGGAAGCTTCGGCTACTACCTGTCGGGCGGCAACGTCAAGAGCAACGGCTTCCACTCCTTCAACGCC
ACCGAAAACAACAACGCCTATGCCAAGCTCCGCTGGAACCTAGCCGACCGGGGAAGCTTACGTCTAACCTTCAATTCCAT
GGAGACGGCGCCGCAGATTGGCCTGATTACGTTTGCTGACTATTCCGATCGACTCAAGATCCGCTTCCTCCAGTCGACTA
TCTCTCTCGACTACAATCTGACCGACCGACTCACTTTCAACACGTTCTTTAAGGGTAGCCGGTTTGACTATACCCGTATT
GATGACACCCTCAGCACTGGCGAACGTTTCTCCACCATCACCAGCGACGAAATAACATCAGGCGGTGCGGCCATCCTCAC
TTGGCGCCAGGGGGTCCACACCCTGACCGGCGGAGTCGAGTTCGACCATGGCCAGACCAAGACGAGCTTTGACTACCCTC
TTTTCCTGTTCAACCAAACGATCGACGCCTCCAACGACAAGTGGGGCTTCTTCCTAAACGACACCATCACCTGGGAGCGG
TTCAGCATCACCCCGGCGGTCCGCTACGACCTCACCAGCCACTCCGGCGACTTCTTCAGCCCGAGCCTCGGGGCCACCTT
CAGCGTCACGGATAAAACCCTGCTCCGGGCCTACGCCGCCCGGGGCTACAACTTGCCGATCCTGAACCCGGCTTATTCCA
CCAAAGACAACGGTTGGACCGTACAGGCCGGCCTCGAAACCACCGATATCCCCTTCCTCTGGCTCAAAGGGACTTGGTTC
CGCAATCAATTCAAAGAGCGGGGTGATACCGTAACAAGGACGCTACGGGAAGGATTTGAGATAGAGGCCCGCACCGCACC
GATTTACAACTCATGGCTCACCGCCGGATATGTCTTCACCGACGCCAAGAACCTCCAGACCGACGAGAAACTTCCCGCAG
TCGCCCGGCACACCTGGGACCTGGGACTTCACTACGACGACCGAACCTTCCGCGGCGCTCTCACCGGTGCGTATCGCTGG
TGGAACACCCCCGATTACTTCGGGGCCGAATACAACAACTTCATCTGGGACCTCAACCTAGGGTGGCGCTTCTTCCGGAG
CGACAACACGGAGGCCGAGCTCTTCGCCACCGGCCACAACCTGTTCAACGGTGCCCAGTATCACGACGAGATATTCAAAA
ACCCCGGCCGCTGGTTCGAAGGCGGCCTGCGCATCAAGTGGTAA

Upstream 100 bases:

>100_bases
TCATTACCCTTTCGGACAAAAAGCGATAGACATTCGTCCTGCTCCTCTGCTATAAGCCATACGTCTGTTCCAACTTTGCC
AGCTCATCAAAGCAAGCCCC

Downstream 100 bases:

>100_bases
AGAAAACGATTTAGGAACCCATGACGGCACGTATCTTCCACATACTCGCCTTGCTGCTCCTCTGGGGCTTCCCGGCTTTC
GCCGCGGAGGTCGTGGTGGT

Product: ferric enterobactin receptor

Products: NA

Alternate protein names: Cobalamin receptor; Outer membrane cobalamin translocator [H]

Number of amino acids: Translated: 627; Mature: 626

Protein sequence:

>627_residues
MPTASPINTAKSRAGSTFRRLSSLLPGLFFFLGLLALTLPFTAHAETDSDRELLELYYEPQDLTVSTATRSPRPLSRSAE
NITVITAEQIEAMNAHTLADVLATVPGVQVSGNTAPASITFTEFAGATTRYIQILVDGVPIDDQFDNFAAPGMVPVQIIE
RVEVLKGPASSSWGNSLGGIVNVITKEPALHASFSGAASFSGGENGTRDGRGEVSGTVGSFGYYLSGGNVKSNGFHSFNA
TENNNAYAKLRWNLADRGSLRLTFNSMETAPQIGLITFADYSDRLKIRFLQSTISLDYNLTDRLTFNTFFKGSRFDYTRI
DDTLSTGERFSTITSDEITSGGAAILTWRQGVHTLTGGVEFDHGQTKTSFDYPLFLFNQTIDASNDKWGFFLNDTITWER
FSITPAVRYDLTSHSGDFFSPSLGATFSVTDKTLLRAYAARGYNLPILNPAYSTKDNGWTVQAGLETTDIPFLWLKGTWF
RNQFKERGDTVTRTLREGFEIEARTAPIYNSWLTAGYVFTDAKNLQTDEKLPAVARHTWDLGLHYDDRTFRGALTGAYRW
WNTPDYFGAEYNNFIWDLNLGWRFFRSDNTEAELFATGHNLFNGAQYHDEIFKNPGRWFEGGLRIKW

Sequences:

>Translated_627_residues
MPTASPINTAKSRAGSTFRRLSSLLPGLFFFLGLLALTLPFTAHAETDSDRELLELYYEPQDLTVSTATRSPRPLSRSAE
NITVITAEQIEAMNAHTLADVLATVPGVQVSGNTAPASITFTEFAGATTRYIQILVDGVPIDDQFDNFAAPGMVPVQIIE
RVEVLKGPASSSWGNSLGGIVNVITKEPALHASFSGAASFSGGENGTRDGRGEVSGTVGSFGYYLSGGNVKSNGFHSFNA
TENNNAYAKLRWNLADRGSLRLTFNSMETAPQIGLITFADYSDRLKIRFLQSTISLDYNLTDRLTFNTFFKGSRFDYTRI
DDTLSTGERFSTITSDEITSGGAAILTWRQGVHTLTGGVEFDHGQTKTSFDYPLFLFNQTIDASNDKWGFFLNDTITWER
FSITPAVRYDLTSHSGDFFSPSLGATFSVTDKTLLRAYAARGYNLPILNPAYSTKDNGWTVQAGLETTDIPFLWLKGTWF
RNQFKERGDTVTRTLREGFEIEARTAPIYNSWLTAGYVFTDAKNLQTDEKLPAVARHTWDLGLHYDDRTFRGALTGAYRW
WNTPDYFGAEYNNFIWDLNLGWRFFRSDNTEAELFATGHNLFNGAQYHDEIFKNPGRWFEGGLRIKW
>Mature_626_residues
PTASPINTAKSRAGSTFRRLSSLLPGLFFFLGLLALTLPFTAHAETDSDRELLELYYEPQDLTVSTATRSPRPLSRSAEN
ITVITAEQIEAMNAHTLADVLATVPGVQVSGNTAPASITFTEFAGATTRYIQILVDGVPIDDQFDNFAAPGMVPVQIIER
VEVLKGPASSSWGNSLGGIVNVITKEPALHASFSGAASFSGGENGTRDGRGEVSGTVGSFGYYLSGGNVKSNGFHSFNAT
ENNNAYAKLRWNLADRGSLRLTFNSMETAPQIGLITFADYSDRLKIRFLQSTISLDYNLTDRLTFNTFFKGSRFDYTRID
DTLSTGERFSTITSDEITSGGAAILTWRQGVHTLTGGVEFDHGQTKTSFDYPLFLFNQTIDASNDKWGFFLNDTITWERF
SITPAVRYDLTSHSGDFFSPSLGATFSVTDKTLLRAYAARGYNLPILNPAYSTKDNGWTVQAGLETTDIPFLWLKGTWFR
NQFKERGDTVTRTLREGFEIEARTAPIYNSWLTAGYVFTDAKNLQTDEKLPAVARHTWDLGLHYDDRTFRGALTGAYRWW
NTPDYFGAEYNNFIWDLNLGWRFFRSDNTEAELFATGHNLFNGAQYHDEIFKNPGRWFEGGLRIKW

Specific function: Involved in the active translocation of vitamin B12 (cyanocobalamin) across the outer membrane to the periplasmic space. It derives its energy for transport by interacting with the trans-periplasmic membrane protein TonB [H]

COG id: COG4206

COG function: function code H; Outer membrane cobalamin receptor protein

Gene ontology:

Cell location: Cell outer membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the TonB-dependent receptor family. BtuB (TC 1.B.14.3.1) subfamily [H]

Homologues:

Organism=Escherichia coli, GI1788478, Length=416, Percent_Identity=26.6826923076923, Blast_Score=77, Evalue=4e-15,
Organism=Escherichia coli, GI1790405, Length=136, Percent_Identity=30.1470588235294, Blast_Score=71, Evalue=2e-13,
Organism=Escherichia coli, GI1786798, Length=147, Percent_Identity=30.6122448979592, Blast_Score=64, Evalue=3e-11,
Organism=Escherichia coli, GI1787723, Length=271, Percent_Identity=26.9372693726937, Blast_Score=63, Evalue=5e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR012910
- InterPro:   IPR000531 [H]

Pfam domain/function: PF07715 Plug; PF00593 TonB_dep_Rec [H]

EC number: NA

Molecular weight: Translated: 69824; Mature: 69693

Theoretical pI: Translated: 5.37; Mature: 5.37

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
0.6 %Met     (Translated Protein)
0.6 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
0.5 %Met     (Mature Protein)
0.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPTASPINTAKSRAGSTFRRLSSLLPGLFFFLGLLALTLPFTAHAETDSDRELLELYYEP
CCCCCCCHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHCCCEECCCCCCCHHHHHEEECC
QDLTVSTATRSPRPLSRSAENITVITAEQIEAMNAHTLADVLATVPGVQVSGNTAPASIT
CCCEEEECCCCCCCCCCCCCCEEEEEHHHHHHHHHHHHHHHHHHCCCEEEECCCCCCEEE
FTEFAGATTRYIQILVDGVPIDDQFDNFAAPGMVPVQIIERVEVLKGPASSSWGNSLGGI
EHHHCCCCEEEEEEEECCCCCCCCCCCCCCCCCHHHHHHHHHHHHCCCCCCCCCCCCCHH
VNVITKEPALHASFSGAASFSGGENGTRDGRGEVSGTVGSFGYYLSGGNVKSNGFHSFNA
HEEEECCCCCEECCCCCCCCCCCCCCCCCCCCCCCCCCCCCEEEEECCCCCCCCEEEECC
TENNNAYAKLRWNLADRGSLRLTFNSMETAPQIGLITFADYSDRLKIRFLQSTISLDYNL
CCCCCEEEEEEEEECCCCEEEEEECCCCCCCCEEEEEEECCCCCEEEEEEEEHEEECCCC
TDRLTFNTFFKGSRFDYTRIDDTLSTGERFSTITSDEITSGGAAILTWRQGVHTLTGGVE
CCCEEEEEEECCCCCCCCCCCCHHCCCCHHEEECCCCCCCCCEEEEEECCCCEEHCCCEE
FDHGQTKTSFDYPLFLFNQTIDASNDKWGFFLNDTITWERFSITPAVRYDLTSHSGDFFS
ECCCCCCCCCCCEEEEEECEECCCCCCEEEEECCEEEEEEEECCCEEEEEECCCCCCCCC
PSLGATFSVTDKTLLRAYAARGYNLPILNPAYSTKDNGWTVQAGLETTDIPFLWLKGTWF
CCCCCEEEECHHHHHHHHHHCCCCCCEECCCCCCCCCCEEEEECCCCCCCCEEEEECCHH
RNQFKERGDTVTRTLREGFEIEARTAPIYNSWLTAGYVFTDAKNLQTDEKLPAVARHTWD
HHHHHHHCHHHHHHHHCCCEEEEECCCCHHHHHHCCEEEECCCCCCCCCCCCHHHHCEEE
LGLHYDDRTFRGALTGAYRWWNTPDYFGAEYNNFIWDLNLGWRFFRSDNTEAELFATGHN
EEEEECCCHHHHHHHCCEECCCCCCCCCCCCCCEEEEECCCEEEEECCCCCEEEEEECCC
LFNGAQYHDEIFKNPGRWFEGGLRIKW
CCCCCHHHHHHHCCCCCEECCCEEEEC
>Mature Secondary Structure 
PTASPINTAKSRAGSTFRRLSSLLPGLFFFLGLLALTLPFTAHAETDSDRELLELYYEP
CCCCCCHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHCCCEECCCCCCCHHHHHEEECC
QDLTVSTATRSPRPLSRSAENITVITAEQIEAMNAHTLADVLATVPGVQVSGNTAPASIT
CCCEEEECCCCCCCCCCCCCCEEEEEHHHHHHHHHHHHHHHHHHCCCEEEECCCCCCEEE
FTEFAGATTRYIQILVDGVPIDDQFDNFAAPGMVPVQIIERVEVLKGPASSSWGNSLGGI
EHHHCCCCEEEEEEEECCCCCCCCCCCCCCCCCHHHHHHHHHHHHCCCCCCCCCCCCCHH
VNVITKEPALHASFSGAASFSGGENGTRDGRGEVSGTVGSFGYYLSGGNVKSNGFHSFNA
HEEEECCCCCEECCCCCCCCCCCCCCCCCCCCCCCCCCCCCEEEEECCCCCCCCEEEECC
TENNNAYAKLRWNLADRGSLRLTFNSMETAPQIGLITFADYSDRLKIRFLQSTISLDYNL
CCCCCEEEEEEEEECCCCEEEEEECCCCCCCCEEEEEEECCCCCEEEEEEEEHEEECCCC
TDRLTFNTFFKGSRFDYTRIDDTLSTGERFSTITSDEITSGGAAILTWRQGVHTLTGGVE
CCCEEEEEEECCCCCCCCCCCCHHCCCCHHEEECCCCCCCCCEEEEEECCCCEEHCCCEE
FDHGQTKTSFDYPLFLFNQTIDASNDKWGFFLNDTITWERFSITPAVRYDLTSHSGDFFS
ECCCCCCCCCCCEEEEEECEECCCCCCEEEEECCEEEEEEEECCCEEEEEECCCCCCCCC
PSLGATFSVTDKTLLRAYAARGYNLPILNPAYSTKDNGWTVQAGLETTDIPFLWLKGTWF
CCCCCEEEECHHHHHHHHHHCCCCCCEECCCCCCCCCCEEEEECCCCCCCCEEEEECCHH
RNQFKERGDTVTRTLREGFEIEARTAPIYNSWLTAGYVFTDAKNLQTDEKLPAVARHTWD
HHHHHHHCHHHHHHHHCCCEEEEECCCCHHHHHHCCEEEECCCCCCCCCCCCHHHHCEEE
LGLHYDDRTFRGALTGAYRWWNTPDYFGAEYNNFIWDLNLGWRFFRSDNTEAELFATGHN
EEEEECCCHHHHHHHCCEECCCCCCCCCCCCCCEEEEECCCEEEEECCCCCEEEEEECCC
LFNGAQYHDEIFKNPGRWFEGGLRIKW
CCCCCHHHHHHHCCCCCEECCCEEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA