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The map label for this gene is cph1 [H]

Identifier: 39995987

GI number: 39995987

Start: 939825

End: 941399

Strand: Reverse

Name: cph1 [H]

Synonym: GSU0881

Alternate gene names: 39995987

Gene position: 941399-939825 (Counterclockwise)

Preceding gene: 39995988

Following gene: 39995986

Centisome position: 24.68

GC content: 65.78

Gene sequence:

>1575_bases
ATGGGTGCGAACGCTCCTCCAGTGCGTTCTTTTTTTGCCGTTCTCCGCACGAGCTTCCGGGCGAAGCTCTTTACGGTGAT
CTGTCTCTCGATCATCGCCCTCTCCGCCTGTTTTGCCGCCTTCTTCCTCTACAACCAGTACCGCTCCCTGCACGACAAGC
TCCTCACCGAGGGCCGGCTCATGACGCGGCTCCTGGCCCACAACGCGCGGCTCCCCCTTTTCGCGGGCAACACCGACCAG
CTTCAGGAGGTGGTCCAGGGAGTCACGGGCCACGGCACTGTGCTTGAAACGGCAATCCTGGACCGGGAAGGGCATCCGCT
GGCCCACTTCGTCCGCCAAAATCCGCGTAACGACAAAAGTACTCCAACGGCTTTTTCCCCGCCCGGCCCTGGGGTGGAGG
GACGCATCCGCGACGGACAGGACTCCCTGGAGTTCGTGGAGCCGATCCTGACCCAGCATTCGGCCGGCAACGAGGAAGAC
CTCTTCTTCGAGGGCGGCCGTGAAAGCAGTACTGTCATCGGATCGGTGCACCTGGTGATGGACGAGAGGCCGCTCCACCG
GAAAGTGAACCAGCTGGCAGCCACGGCGCTGCTGGTTACCGCCGCTGCGCTGGTGGCGGTAATCGGAGCACTCTACCCCG
TGATCAGGGGAATTACCCGGCCACTGACCCACCTGGAGCGGGGGGTCAGGGAGATCGCTGCGGGCAACAAAGAGGTGCGG
GTGCCGGTGGAGTCCCAGGACGAGTTGGGGTCCCTGGCGGCGTCGTTCAACAGCATGGCCGAGTCGCTGCTCCAGCGCAA
GCTGGCCCAGGAGGAGTCGGAGCGCAAGATTCGGGAACTGAACGTCAACCTTGAGGAGATGGTGCGCCGGCGGACCGCCG
AGCTCATGGCGGCCAACCGGGAACTGGAGTCGTTCAATTACTCGGCCTCCCACGATCTGCGGGCGCCGCTGCTCCGGCTG
CGCGGCCTGTGCCAGGCCCTTGAGGAGGACTGCGGCGACCGCCTGGACGGGGAGCTGCGGGACTACCTGGACCGGATCGC
CGAGGTGGGGGTTCAGATGGAGCGGGTCATGTCCGCCATGTCGAGCCTGTTCCGGGTTCAGCGCCGGGAGCTTGAACTGC
AGCCGGTGAACCTGAGCGAACTGGTGGAGAAGGTGGTTGCGGCCCACCGGGCAACGGAACCCCAGCGGCAGGTGGCGGTG
TCGGTGGAACCGGGGGCCGCGGCCACGGGGGACCCTGAGCTCCTCTGGGTGGCCCTGGACAACCTGATCGGCAATGCCTG
GAAGTTCACCTCCCGCAGGGCCGACGCGCGGATCGAGTTCGGCAGCATGCACCAGGAGGGAGAGCTCGTCTGCTTCATCC
GCGACAACGGCGCCGGCTTCAACATGGGCTATGCCCACAAGATCTTCGAGCCGTTCCATCGACTCCACGGCCAGGACGAG
TTCCCCGGTACCGGCGTGGGGCTGGCCATCGTGCAGCGGATCATTTCCCGCCACCAGGGCCGTGTCTGGCTCGAAAGCGC
CGAGGGGGCGGGTACCACCTGCTACTTCACCCTCCCGGAGAGTGCCCCGGCCTGA

Upstream 100 bases:

>100_bases
GAGCGTACCGGCCGAAGGCCCGGCACGGCCGACCCTCAAGCTGAACGGCTCGGTGGCGCGCCACCTGGGAATCGACCCGG
CACGACTCGGAGAGTAACCA

Downstream 100 bases:

>100_bases
TCCTCCCAGGGAGGCGACCATGCCCGAACTGAAGCGTTCCGTCTGTCCCTATGACTGCCCCGACACCTGCGGCTTGCTGG
TGGAGGTCGAGAACGGCCGT

Product: sensor histidine kinase

Products: NA

Alternate protein names: Bacteriophytochrome cph1; Light-regulated histidine kinase 1 [H]

Number of amino acids: Translated: 524; Mature: 523

Protein sequence:

>524_residues
MGANAPPVRSFFAVLRTSFRAKLFTVICLSIIALSACFAAFFLYNQYRSLHDKLLTEGRLMTRLLAHNARLPLFAGNTDQ
LQEVVQGVTGHGTVLETAILDREGHPLAHFVRQNPRNDKSTPTAFSPPGPGVEGRIRDGQDSLEFVEPILTQHSAGNEED
LFFEGGRESSTVIGSVHLVMDERPLHRKVNQLAATALLVTAAALVAVIGALYPVIRGITRPLTHLERGVREIAAGNKEVR
VPVESQDELGSLAASFNSMAESLLQRKLAQEESERKIRELNVNLEEMVRRRTAELMAANRELESFNYSASHDLRAPLLRL
RGLCQALEEDCGDRLDGELRDYLDRIAEVGVQMERVMSAMSSLFRVQRRELELQPVNLSELVEKVVAAHRATEPQRQVAV
SVEPGAAATGDPELLWVALDNLIGNAWKFTSRRADARIEFGSMHQEGELVCFIRDNGAGFNMGYAHKIFEPFHRLHGQDE
FPGTGVGLAIVQRIISRHQGRVWLESAEGAGTTCYFTLPESAPA

Sequences:

>Translated_524_residues
MGANAPPVRSFFAVLRTSFRAKLFTVICLSIIALSACFAAFFLYNQYRSLHDKLLTEGRLMTRLLAHNARLPLFAGNTDQ
LQEVVQGVTGHGTVLETAILDREGHPLAHFVRQNPRNDKSTPTAFSPPGPGVEGRIRDGQDSLEFVEPILTQHSAGNEED
LFFEGGRESSTVIGSVHLVMDERPLHRKVNQLAATALLVTAAALVAVIGALYPVIRGITRPLTHLERGVREIAAGNKEVR
VPVESQDELGSLAASFNSMAESLLQRKLAQEESERKIRELNVNLEEMVRRRTAELMAANRELESFNYSASHDLRAPLLRL
RGLCQALEEDCGDRLDGELRDYLDRIAEVGVQMERVMSAMSSLFRVQRRELELQPVNLSELVEKVVAAHRATEPQRQVAV
SVEPGAAATGDPELLWVALDNLIGNAWKFTSRRADARIEFGSMHQEGELVCFIRDNGAGFNMGYAHKIFEPFHRLHGQDE
FPGTGVGLAIVQRIISRHQGRVWLESAEGAGTTCYFTLPESAPA
>Mature_523_residues
GANAPPVRSFFAVLRTSFRAKLFTVICLSIIALSACFAAFFLYNQYRSLHDKLLTEGRLMTRLLAHNARLPLFAGNTDQL
QEVVQGVTGHGTVLETAILDREGHPLAHFVRQNPRNDKSTPTAFSPPGPGVEGRIRDGQDSLEFVEPILTQHSAGNEEDL
FFEGGRESSTVIGSVHLVMDERPLHRKVNQLAATALLVTAAALVAVIGALYPVIRGITRPLTHLERGVREIAAGNKEVRV
PVESQDELGSLAASFNSMAESLLQRKLAQEESERKIRELNVNLEEMVRRRTAELMAANRELESFNYSASHDLRAPLLRLR
GLCQALEEDCGDRLDGELRDYLDRIAEVGVQMERVMSAMSSLFRVQRRELELQPVNLSELVEKVVAAHRATEPQRQVAVS
VEPGAAATGDPELLWVALDNLIGNAWKFTSRRADARIEFGSMHQEGELVCFIRDNGAGFNMGYAHKIFEPFHRLHGQDEF
PGTGVGLAIVQRIISRHQGRVWLESAEGAGTTCYFTLPESAPA

Specific function: Regulatory photoreceptor which exists in two forms that are reversibly interconvertible by light:the R form that absorbs maximally in the red region of the spectrum and the FR form that absorbs maximally in the far-red region. Has also a slight blue shift

COG id: COG0642

COG function: function code T; Signal transduction histidine kinase

Gene ontology:

Cell location: Integral Membrane Protein. Inner Membrane [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PAS (PER-ARNT-SIM) domain [H]

Homologues:

Organism=Escherichia coli, GI1789149, Length=528, Percent_Identity=22.7272727272727, Blast_Score=88, Evalue=1e-18,
Organism=Escherichia coli, GI1788549, Length=238, Percent_Identity=29.4117647058824, Blast_Score=86, Evalue=6e-18,
Organism=Escherichia coli, GI48994928, Length=250, Percent_Identity=27.2, Blast_Score=80, Evalue=2e-16,
Organism=Escherichia coli, GI1788393, Length=310, Percent_Identity=27.0967741935484, Blast_Score=79, Evalue=5e-16,
Organism=Escherichia coli, GI1789808, Length=322, Percent_Identity=25.1552795031056, Blast_Score=78, Evalue=1e-15,
Organism=Escherichia coli, GI87081816, Length=342, Percent_Identity=24.5614035087719, Blast_Score=74, Evalue=3e-14,
Organism=Escherichia coli, GI145693157, Length=251, Percent_Identity=25.0996015936255, Blast_Score=72, Evalue=6e-14,
Organism=Escherichia coli, GI1790346, Length=307, Percent_Identity=27.3615635179153, Blast_Score=70, Evalue=5e-13,
Organism=Escherichia coli, GI1786783, Length=338, Percent_Identity=25.7396449704142, Blast_Score=68, Evalue=1e-12,
Organism=Escherichia coli, GI1786600, Length=240, Percent_Identity=24.5833333333333, Blast_Score=67, Evalue=4e-12,
Organism=Escherichia coli, GI1786912, Length=241, Percent_Identity=29.4605809128631, Blast_Score=66, Evalue=5e-12,
Organism=Escherichia coli, GI1788713, Length=224, Percent_Identity=24.5535714285714, Blast_Score=65, Evalue=1e-11,
Organism=Escherichia coli, GI1790861, Length=329, Percent_Identity=24.3161094224924, Blast_Score=64, Evalue=3e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR003018
- InterPro:   IPR000014
- InterPro:   IPR013654
- InterPro:   IPR016132
- InterPro:   IPR001294
- InterPro:   IPR013515
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR009082 [H]

Pfam domain/function: PF01590 GAF; PF02518 HATPase_c; PF00512 HisKA; PF08446 PAS_2; PF00360 Phytochrome [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 57985; Mature: 57854

Theoretical pI: Translated: 6.31; Mature: 6.31

Prosite motif: PS50885 HAMP ; PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGANAPPVRSFFAVLRTSFRAKLFTVICLSIIALSACFAAFFLYNQYRSLHDKLLTEGRL
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
MTRLLAHNARLPLFAGNTDQLQEVVQGVTGHGTVLETAILDREGHPLAHFVRQNPRNDKS
HHHHHHCCCCCCEEECCHHHHHHHHHCCCCCCHHHHHHHHCCCCCHHHHHHHCCCCCCCC
TPTAFSPPGPGVEGRIRDGQDSLEFVEPILTQHSAGNEEDLFFEGGRESSTVIGSVHLVM
CCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHCCCCCCCCEEEECCCCCCEEEEEEEEEE
DERPLHRKVNQLAATALLVTAAALVAVIGALYPVIRGITRPLTHLERGVREIAAGNKEVR
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEE
VPVESQDELGSLAASFNSMAESLLQRKLAQEESERKIRELNVNLEEMVRRRTAELMAANR
ECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHH
ELESFNYSASHDLRAPLLRLRGLCQALEEDCGDRLDGELRDYLDRIAEVGVQMERVMSAM
HHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHH
SSLFRVQRRELELQPVNLSELVEKVVAAHRATEPQRQVAVSVEPGAAATGDPELLWVALD
HHHHHHHHHHCCCCCCCHHHHHHHHHHHHHCCCHHHCEEEEECCCCCCCCCCHHHHHHHH
NLIGNAWKFTSRRADARIEFGSMHQEGELVCFIRDNGAGFNMGYAHKIFEPFHRLHGQDE
HHHCCHHHHHCCCCCCEEEECCCCCCCCEEEEEECCCCCCCCCHHHHHHHHHHHHCCCCC
FPGTGVGLAIVQRIISRHQGRVWLESAEGAGTTCYFTLPESAPA
CCCCCHHHHHHHHHHHHCCCCEEEECCCCCCCEEEEECCCCCCC
>Mature Secondary Structure 
GANAPPVRSFFAVLRTSFRAKLFTVICLSIIALSACFAAFFLYNQYRSLHDKLLTEGRL
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
MTRLLAHNARLPLFAGNTDQLQEVVQGVTGHGTVLETAILDREGHPLAHFVRQNPRNDKS
HHHHHHCCCCCCEEECCHHHHHHHHHCCCCCCHHHHHHHHCCCCCHHHHHHHCCCCCCCC
TPTAFSPPGPGVEGRIRDGQDSLEFVEPILTQHSAGNEEDLFFEGGRESSTVIGSVHLVM
CCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHCCCCCCCCEEEECCCCCCEEEEEEEEEE
DERPLHRKVNQLAATALLVTAAALVAVIGALYPVIRGITRPLTHLERGVREIAAGNKEVR
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEE
VPVESQDELGSLAASFNSMAESLLQRKLAQEESERKIRELNVNLEEMVRRRTAELMAANR
ECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHH
ELESFNYSASHDLRAPLLRLRGLCQALEEDCGDRLDGELRDYLDRIAEVGVQMERVMSAM
HHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHH
SSLFRVQRRELELQPVNLSELVEKVVAAHRATEPQRQVAVSVEPGAAATGDPELLWVALD
HHHHHHHHHHCCCCCCCHHHHHHHHHHHHHCCCHHHCEEEEECCCCCCCCCCHHHHHHHH
NLIGNAWKFTSRRADARIEFGSMHQEGELVCFIRDNGAGFNMGYAHKIFEPFHRLHGQDE
HHHCCHHHHHCCCCCCEEEECCCCCCCCEEEEEECCCCCCCCCHHHHHHHHHHHHCCCCC
FPGTGVGLAIVQRIISRHQGRVWLESAEGAGTTCYFTLPESAPA
CCCCCHHHHHHHHHHHHCCCCEEEECCCCCCCEEEEECCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8590279; 8905231; 9109482; 9278513; 10828948 [H]