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The map label for this gene is yoaE [H]

Identifier: 39995986

GI number: 39995986

Start: 937790

End: 939805

Strand: Reverse

Name: yoaE [H]

Synonym: GSU0880

Alternate gene names: 39995986

Gene position: 939805-937790 (Counterclockwise)

Preceding gene: 39995987

Following gene: 39995985

Centisome position: 24.64

GC content: 69.79

Gene sequence:

>2016_bases
ATGCCCGAACTGAAGCGTTCCGTCTGTCCCTATGACTGCCCCGACACCTGCGGCTTGCTGGTGGAGGTCGAGAACGGCCG
TGCGGTGCGCGTGACCGGCGATCCAGACCACCCCTTCACCCGGGGCACCCTCTGCCCCAAGATGCTCCACTATGAAAAGA
CGGTCCACTCTTCCCGGCGGCTGACCACTCCGCTCGTGCGGACCGGCCCCAAGGGGAGCGGTTCGTTCCGGCCCGCGTCG
TGGGACGAGACCGTTGCCGCCATTGCATCCCGCTGGCGCGAGATCATCGCCGTCCACGGAGCCGAGGCGATCCTCCCCTA
TTCCTACGCGGGCACCATGGGACTGGTGCAGCGCAATGCCGGTCACCCCTTCTTCCACCGGCTGGGGGCGTCGCGGCTGG
AGCGGACCATCTGCTCACCGGCCAAGGAGGCGGGGTGGAAGGCAGTAATGGGCGATACTCCGGCCCCCCATCCGGACGAA
GTGGCGGAGAGCGACCTGGTAATCCTCTGGGGGATCAATGCGGCGGCCACCAATATCCATTTCCTCCACGGAGTGCGCGA
GGCCCGCAGGCGGGGAGCCCCTGTCTGGGTGATCGACACCTACCGGACCCCTACGGCCGCTGCAGCCGACCGGGTGATCC
TGCCCCGCCCCGGCAGCGACGGAGCACTGGCACTGGGGATGATGCACGTGCTGGCCCGGGACGGCCTGGTGGACCGGGCA
TTCCTGGCTGAACGGGTACAGGGGTACGATGAGCTGGCGGAGCGGATTCTCCCGGACTATCCCCCGGAGCGGGTGGCGGC
CCTCACGGGCATCCCGGCGGCGGAGATCGAAGAGCTGGCCCGGCGCTACGGCCGGGCGCGCGCCCCCTTCATCCGCCTGG
GGAGCGGGCTTTCCCGCTACGGCAACGGGGCCATGACGGTGCGCTGCATCGCGGCCCTGCCCGCCCTGACCGGGGCTTAT
GCCGTGCGGGGCGGCGGCTGTCTGGCCTCAACGAGCACCGGTCCCGCCTTTGCCCTGGGAGAGGTGCTGCGTGAGGACTT
CATGGCGCGGCCCACCCGCGTCGTGAACATGAACCGGCTCGGCCACGCCCTGACCGGGCTGGCCGACCCGCCGGTCATGT
CCCTGTATGTGTACCACTCGAACCCGGCCGCGGTGACCCCGGACCAGAACGAGGTGATCCGGGGGCTCTGCCGGGACGAC
CTCTTCACCGTGGTCCACGAGCGGTTCCTGACCGACACGGCCCGTTACGCCGACATCGTGCTGCCGGCCACCTCGTCCCT
AGAGCACGCAGACGTGTACCGGGCCTACGGCACCTACTGCATCCAGCGGGCCCACCCTGCCATCCCGCCCGTGGGGGAGA
GCAGATCCAACTGGGACACCTTCGCCCTGCTGGCCGGGGCCATGGGGTTCGAGGAGGAGTTTTTCCGCCGGAGCGCCGGG
GAGATGATCGACCGGCTCCTGTCGGTCCCCACCGCCATGCGGGCCGGGATCGACCAGGTCCGTTTCGACGCGGGTCTGGC
CGTGGAACTCCCCCTGGCCCCCGATGCCCCGCGCATCTTCGCCACTCCCTCGGGCAAGGTGGAGATCCTCAATCCCCGCG
AGCCTGAACCACTCCCCCGTCACATTCCTTGCCACGAAGACGCGGGCGAGCTTCCCCTCAGGCTCATGACCGCCCCCACC
CCCTACGCCCTGAACGCCTCCTTCTACGAGCAGGAAGAGCTGCGGCAGAAGCAGGGGGGCGCCATGTCGCTCCTCCTGAA
CCCGGCCGAGGCAACAGCCCGGAACCTGGCCGAGGGGCAGCGGGTGACCGCCGTCAACGACCGGGGCCGGGTCGCCTTCA
TCCTGCGGATCACCGACCGGGTTCCGCCGGGGGTGGCCGTGGCCGAGGGGGTCTGGTGGCTGGAGCACGCCCCGGGCGAC
CGGACCGTGAACGCCCTCACCAGCCAACGGCTCACGGACCGGGGCAACGGCAGCACATTCTATGATACGCGGATCGAGGT
GCTCCCCGCCCCGTGA

Upstream 100 bases:

>100_bases
CAGGGCCGTGTCTGGCTCGAAAGCGCCGAGGGGGCGGGTACCACCTGCTACTTCACCCTCCCGGAGAGTGCCCCGGCCTG
ATCCTCCCAGGGAGGCGACC

Downstream 100 bases:

>100_bases
CAGCCTTTCCGCAACTTTTTCAACAGCCTGGCTAAAGTTTCCTCATGCATGGCCGATACGTTAACCATGCCTTCATCCGG
AAGGCGATCACTCTGCGAGG

Product: molybdopterin oxidoreductase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 671; Mature: 670

Protein sequence:

>671_residues
MPELKRSVCPYDCPDTCGLLVEVENGRAVRVTGDPDHPFTRGTLCPKMLHYEKTVHSSRRLTTPLVRTGPKGSGSFRPAS
WDETVAAIASRWREIIAVHGAEAILPYSYAGTMGLVQRNAGHPFFHRLGASRLERTICSPAKEAGWKAVMGDTPAPHPDE
VAESDLVILWGINAAATNIHFLHGVREARRRGAPVWVIDTYRTPTAAAADRVILPRPGSDGALALGMMHVLARDGLVDRA
FLAERVQGYDELAERILPDYPPERVAALTGIPAAEIEELARRYGRARAPFIRLGSGLSRYGNGAMTVRCIAALPALTGAY
AVRGGGCLASTSTGPAFALGEVLREDFMARPTRVVNMNRLGHALTGLADPPVMSLYVYHSNPAAVTPDQNEVIRGLCRDD
LFTVVHERFLTDTARYADIVLPATSSLEHADVYRAYGTYCIQRAHPAIPPVGESRSNWDTFALLAGAMGFEEEFFRRSAG
EMIDRLLSVPTAMRAGIDQVRFDAGLAVELPLAPDAPRIFATPSGKVEILNPREPEPLPRHIPCHEDAGELPLRLMTAPT
PYALNASFYEQEELRQKQGGAMSLLLNPAEATARNLAEGQRVTAVNDRGRVAFILRITDRVPPGVAVAEGVWWLEHAPGD
RTVNALTSQRLTDRGNGSTFYDTRIEVLPAP

Sequences:

>Translated_671_residues
MPELKRSVCPYDCPDTCGLLVEVENGRAVRVTGDPDHPFTRGTLCPKMLHYEKTVHSSRRLTTPLVRTGPKGSGSFRPAS
WDETVAAIASRWREIIAVHGAEAILPYSYAGTMGLVQRNAGHPFFHRLGASRLERTICSPAKEAGWKAVMGDTPAPHPDE
VAESDLVILWGINAAATNIHFLHGVREARRRGAPVWVIDTYRTPTAAAADRVILPRPGSDGALALGMMHVLARDGLVDRA
FLAERVQGYDELAERILPDYPPERVAALTGIPAAEIEELARRYGRARAPFIRLGSGLSRYGNGAMTVRCIAALPALTGAY
AVRGGGCLASTSTGPAFALGEVLREDFMARPTRVVNMNRLGHALTGLADPPVMSLYVYHSNPAAVTPDQNEVIRGLCRDD
LFTVVHERFLTDTARYADIVLPATSSLEHADVYRAYGTYCIQRAHPAIPPVGESRSNWDTFALLAGAMGFEEEFFRRSAG
EMIDRLLSVPTAMRAGIDQVRFDAGLAVELPLAPDAPRIFATPSGKVEILNPREPEPLPRHIPCHEDAGELPLRLMTAPT
PYALNASFYEQEELRQKQGGAMSLLLNPAEATARNLAEGQRVTAVNDRGRVAFILRITDRVPPGVAVAEGVWWLEHAPGD
RTVNALTSQRLTDRGNGSTFYDTRIEVLPAP
>Mature_670_residues
PELKRSVCPYDCPDTCGLLVEVENGRAVRVTGDPDHPFTRGTLCPKMLHYEKTVHSSRRLTTPLVRTGPKGSGSFRPASW
DETVAAIASRWREIIAVHGAEAILPYSYAGTMGLVQRNAGHPFFHRLGASRLERTICSPAKEAGWKAVMGDTPAPHPDEV
AESDLVILWGINAAATNIHFLHGVREARRRGAPVWVIDTYRTPTAAAADRVILPRPGSDGALALGMMHVLARDGLVDRAF
LAERVQGYDELAERILPDYPPERVAALTGIPAAEIEELARRYGRARAPFIRLGSGLSRYGNGAMTVRCIAALPALTGAYA
VRGGGCLASTSTGPAFALGEVLREDFMARPTRVVNMNRLGHALTGLADPPVMSLYVYHSNPAAVTPDQNEVIRGLCRDDL
FTVVHERFLTDTARYADIVLPATSSLEHADVYRAYGTYCIQRAHPAIPPVGESRSNWDTFALLAGAMGFEEEFFRRSAGE
MIDRLLSVPTAMRAGIDQVRFDAGLAVELPLAPDAPRIFATPSGKVEILNPREPEPLPRHIPCHEDAGELPLRLMTAPTP
YALNASFYEQEELRQKQGGAMSLLLNPAEATARNLAEGQRVTAVNDRGRVAFILRITDRVPPGVAVAEGVWWLEHAPGDR
TVNALTSQRLTDRGNGSTFYDTRIEVLPAP

Specific function: Terminal Reductase During Anaerobic Growth On Various Sulfoxide And N-Oxide Compounds (By Similarity). [C]

COG id: COG0243

COG function: function code C; Anaerobic dehydrogenases, typically selenocysteine-containing

Gene ontology:

Cell location: Cytoplasm Face Of The Membrane [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the prokaryotic molybdopterin-containing oxidoreductase family [H]

Homologues:

Organism=Escherichia coli, GI1787870, Length=763, Percent_Identity=25.4259501965924, Blast_Score=174, Evalue=2e-44,
Organism=Escherichia coli, GI171474008, Length=752, Percent_Identity=26.5957446808511, Blast_Score=172, Evalue=8e-44,
Organism=Escherichia coli, GI87081797, Length=759, Percent_Identity=25.9552042160738, Blast_Score=171, Evalue=1e-43,
Organism=Escherichia coli, GI3868721, Length=511, Percent_Identity=28.9628180039139, Blast_Score=171, Evalue=1e-43,
Organism=Escherichia coli, GI1787231, Length=706, Percent_Identity=23.9376770538244, Blast_Score=117, Evalue=2e-27,
Organism=Escherichia coli, GI145693196, Length=710, Percent_Identity=25.2112676056338, Blast_Score=117, Evalue=2e-27,
Organism=Escherichia coli, GI87081994, Length=719, Percent_Identity=23.9221140472879, Blast_Score=115, Evalue=1e-26,
Organism=Escherichia coli, GI1788534, Length=495, Percent_Identity=23.6363636363636, Blast_Score=101, Evalue=2e-22,
Organism=Escherichia coli, GI3868720, Length=336, Percent_Identity=26.7857142857143, Blast_Score=75, Evalue=1e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR009010
- InterPro:   IPR006657
- InterPro:   IPR006656
- InterPro:   IPR006963
- InterPro:   IPR006655 [H]

Pfam domain/function: PF04879 Molybdop_Fe4S4; PF00384 Molybdopterin; PF01568 Molydop_binding [H]

EC number: 1.8.99.- [C]

Molecular weight: Translated: 73093; Mature: 72962

Theoretical pI: Translated: 7.01; Mature: 7.01

Prosite motif: PS00490 MOLYBDOPTERIN_PROK_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPELKRSVCPYDCPDTCGLLVEVENGRAVRVTGDPDHPFTRGTLCPKMLHYEKTVHSSRR
CCCHHCCCCCCCCCCCCCEEEEECCCCEEEEECCCCCCCCCCCCCHHHHHHHHHHHCCCC
LTTPLVRTGPKGSGSFRPASWDETVAAIASRWREIIAVHGAEAILPYSYAGTMGLVQRNA
CCCCHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCEECCCCCCCHHHHCCCC
GHPFFHRLGASRLERTICSPAKEAGWKAVMGDTPAPHPDEVAESDLVILWGINAAATNIH
CCHHHHHHHHHHHHHHHHCCHHHCCCEEEECCCCCCCCHHHCCCCEEEEEECCHHHHHHH
FLHGVREARRRGAPVWVIDTYRTPTAAAADRVILPRPGSDGALALGMMHVLARDGLVDRA
HHHHHHHHHHCCCCEEEEECCCCCCHHHCCCEEECCCCCCCHHHHHHHHHHHHCCCHHHH
FLAERVQGYDELAERILPDYPPERVAALTGIPAAEIEELARRYGRARAPFIRLGSGLSRY
HHHHHHCCHHHHHHHHCCCCCHHHHHHHCCCCHHHHHHHHHHHCCCCCCHHHHCCCHHHH
GNGAMTVRCIAALPALTGAYAVRGGGCLASTSTGPAFALGEVLREDFMARPTRVVNMNRL
CCCCCEEHHHHHHHHHHHHHEECCCCEEECCCCCCHHHHHHHHHHHHHCCCCEEEEHHHH
GHALTGLADPPVMSLYVYHSNPAAVTPDQNEVIRGLCRDDLFTVVHERFLTDTARYADIV
HHHHHCCCCCCEEEEEEEECCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEE
LPATSSLEHADVYRAYGTYCIQRAHPAIPPVGESRSNWDTFALLAGAMGFEEEFFRRSAG
ECCCCCCHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHCCHHHHHHHHHHH
EMIDRLLSVPTAMRAGIDQVRFDAGLAVELPLAPDAPRIFATPSGKVEILNPREPEPLPR
HHHHHHHHCCHHHHHCHHHHEECCCCEEEECCCCCCCEEEECCCCCEEEECCCCCCCCCC
HIPCHEDAGELPLRLMTAPTPYALNASFYEQEELRQKQGGAMSLLLNPAEATARNLAEGQ
CCCCCCCCCCCCEEEEECCCCCEECCHHHHHHHHHHHCCCEEEEEECCHHHHHHHHHCCC
RVTAVNDRGRVAFILRITDRVPPGVAVAEGVWWLEHAPGDRTVNALTSQRLTDRGNGSTF
EEEEECCCCCEEEEEEEECCCCCCCCHHCCEEEEECCCCCHHHHHHHHHHHHCCCCCCEE
YDTRIEVLPAP
EECEEEEECCC
>Mature Secondary Structure 
PELKRSVCPYDCPDTCGLLVEVENGRAVRVTGDPDHPFTRGTLCPKMLHYEKTVHSSRR
CCHHCCCCCCCCCCCCCEEEEECCCCEEEEECCCCCCCCCCCCCHHHHHHHHHHHCCCC
LTTPLVRTGPKGSGSFRPASWDETVAAIASRWREIIAVHGAEAILPYSYAGTMGLVQRNA
CCCCHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCEECCCCCCCHHHHCCCC
GHPFFHRLGASRLERTICSPAKEAGWKAVMGDTPAPHPDEVAESDLVILWGINAAATNIH
CCHHHHHHHHHHHHHHHHCCHHHCCCEEEECCCCCCCCHHHCCCCEEEEEECCHHHHHHH
FLHGVREARRRGAPVWVIDTYRTPTAAAADRVILPRPGSDGALALGMMHVLARDGLVDRA
HHHHHHHHHHCCCCEEEEECCCCCCHHHCCCEEECCCCCCCHHHHHHHHHHHHCCCHHHH
FLAERVQGYDELAERILPDYPPERVAALTGIPAAEIEELARRYGRARAPFIRLGSGLSRY
HHHHHHCCHHHHHHHHCCCCCHHHHHHHCCCCHHHHHHHHHHHCCCCCCHHHHCCCHHHH
GNGAMTVRCIAALPALTGAYAVRGGGCLASTSTGPAFALGEVLREDFMARPTRVVNMNRL
CCCCCEEHHHHHHHHHHHHHEECCCCEEECCCCCCHHHHHHHHHHHHHCCCCEEEEHHHH
GHALTGLADPPVMSLYVYHSNPAAVTPDQNEVIRGLCRDDLFTVVHERFLTDTARYADIV
HHHHHCCCCCCEEEEEEEECCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEE
LPATSSLEHADVYRAYGTYCIQRAHPAIPPVGESRSNWDTFALLAGAMGFEEEFFRRSAG
ECCCCCCHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHCCHHHHHHHHHHH
EMIDRLLSVPTAMRAGIDQVRFDAGLAVELPLAPDAPRIFATPSGKVEILNPREPEPLPR
HHHHHHHHCCHHHHHCHHHHEECCCCEEEECCCCCCCEEEECCCCCEEEECCCCCCCCCC
HIPCHEDAGELPLRLMTAPTPYALNASFYEQEELRQKQGGAMSLLLNPAEATARNLAEGQ
CCCCCCCCCCCCEEEEECCCCCEECCHHHHHHHHHHHCCCEEEEEECCHHHHHHHHHCCC
RVTAVNDRGRVAFILRITDRVPPGVAVAEGVWWLEHAPGDRTVNALTSQRLTDRGNGSTF
EEEEECCCCCEEEEEEEECCCCCCCCHHCCEEEEECCCCCHHHHHHHHHHHHCCCCCCEE
YDTRIEVLPAP
EECEEEEECCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: May Bind 4Fe-4S Cluster. [C]

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9384377 [H]