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The map label for this gene is sppA-1 [H]

Identifier: 39995926

GI number: 39995926

Start: 880374

End: 881339

Strand: Direct

Name: sppA-1 [H]

Synonym: GSU0820

Alternate gene names: 39995926

Gene position: 880374-881339 (Clockwise)

Preceding gene: 39995925

Following gene: 39995929

Centisome position: 23.08

GC content: 67.39

Gene sequence:

>966_bases
ATGAGGATGATCATCGCGTTTCTGCTCGGCTGCCTCGGCATGTTCCTGACAACGGGGTGCGCCTTTGTCAGCGTGCCGCT
CATGAGTGCGCCTCAGCCCCTGGCCGAACAGGTGCTGGAAGGGGAGGGGACGAAAAAGATCCTGATCGTGGACATAAGCG
GCGCCATCGGCGATCAGGCCAAGGGGGGCGGCCTGCTGAGCCGGGGAACCCCCTCCACGGTCTCCCTGGTGCGGGAGGTC
CTCCTGAAGGCCGAGCGCGATCCCAAGGTGGCCGGGCTGATCCTGCGGATCAATTCGCCCGGGGGGACGGTGACGGCCAG
CGACATCATCCGCCACGACCTGCTCGCCTTCAAGGAGCGCCGGAATCTGCCGGTGTCCGCCTGCATCATGGGGATCGGCG
CCTCGGGTGGCTACTACGTGGCCACCGCCGCCGACGGGATAACCGCCCATCCCACGGCCCTGACCGGGAGCATCGGGGTG
CTGCTCATGACCTTCAACGTGGAGGGATTGCTGGGGAAGGTGGGTGTGGAGGAGAAGACCATCAAGTCGGGCGGGAAAAA
GGACCTCCTGTCGCCGTTCCGCCGCGCCACCCCGGAGGAGGAGCGGCTGGTTCAGGGGGTCATCGACCAGTTCCACGGGC
GCTTCGTGGACGTGGTCCAGGCCCGGCCGGGGAACCGGCTTTCGCGCCACGACCTGCTCACGCTGGCCGACGGCCGCATC
TTCTCCGCCGCCGACGCCCTTGCCGCGGGCCTCATCGACCGGATCGGCTACCTGGACGACGTCATCGCCTCCCTGCGTGA
CCGCATAGGAGATCCCGACGCCCGGGTTGTCACCTACTTCCGACCCGGCAGCTACCAGGGGAGCATCTATGCGGAGTCGG
CAGCCGAGCCGTCCATGGCGGACCTGCTGGGCGGGTTCGACATGACTGGCGGCGGCCAGTTCATGTATCTCTGGCGCCCC
TGGTGA

Upstream 100 bases:

>100_bases
GGGTGGACGGCCGGGAGGAGTTCACCGTCTATCTTGCGCCGGTGGGGAAGGTGTGATTGAATCTCTCAACCGACGTGCCG
CTGACATACGGGAGGGTACC

Downstream 100 bases:

>100_bases
TCGACAGCCCGCCAGTGGCCGGGCTCAGCGGCGCTCTTCGCCCTGTTCCCGTTCCTTTTCCAGTTCCTGCCGGAGACGCT
CCAGCCCCTTGCTGAAGCTT

Product: signal peptide peptidase SppA, 36K type

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 321; Mature: 321

Protein sequence:

>321_residues
MRMIIAFLLGCLGMFLTTGCAFVSVPLMSAPQPLAEQVLEGEGTKKILIVDISGAIGDQAKGGGLLSRGTPSTVSLVREV
LLKAERDPKVAGLILRINSPGGTVTASDIIRHDLLAFKERRNLPVSACIMGIGASGGYYVATAADGITAHPTALTGSIGV
LLMTFNVEGLLGKVGVEEKTIKSGGKKDLLSPFRRATPEEERLVQGVIDQFHGRFVDVVQARPGNRLSRHDLLTLADGRI
FSAADALAAGLIDRIGYLDDVIASLRDRIGDPDARVVTYFRPGSYQGSIYAESAAEPSMADLLGGFDMTGGGQFMYLWRP
W

Sequences:

>Translated_321_residues
MRMIIAFLLGCLGMFLTTGCAFVSVPLMSAPQPLAEQVLEGEGTKKILIVDISGAIGDQAKGGGLLSRGTPSTVSLVREV
LLKAERDPKVAGLILRINSPGGTVTASDIIRHDLLAFKERRNLPVSACIMGIGASGGYYVATAADGITAHPTALTGSIGV
LLMTFNVEGLLGKVGVEEKTIKSGGKKDLLSPFRRATPEEERLVQGVIDQFHGRFVDVVQARPGNRLSRHDLLTLADGRI
FSAADALAAGLIDRIGYLDDVIASLRDRIGDPDARVVTYFRPGSYQGSIYAESAAEPSMADLLGGFDMTGGGQFMYLWRP
W
>Mature_321_residues
MRMIIAFLLGCLGMFLTTGCAFVSVPLMSAPQPLAEQVLEGEGTKKILIVDISGAIGDQAKGGGLLSRGTPSTVSLVREV
LLKAERDPKVAGLILRINSPGGTVTASDIIRHDLLAFKERRNLPVSACIMGIGASGGYYVATAADGITAHPTALTGSIGV
LLMTFNVEGLLGKVGVEEKTIKSGGKKDLLSPFRRATPEEERLVQGVIDQFHGRFVDVVQARPGNRLSRHDLLTLADGRI
FSAADALAAGLIDRIGYLDDVIASLRDRIGDPDARVVTYFRPGSYQGSIYAESAAEPSMADLLGGFDMTGGGQFMYLWRP
W

Specific function: Digestion of the cleaved signal peptides [H]

COG id: COG0616

COG function: function code OU; Periplasmic serine proteases (ClpP class)

Gene ontology:

Cell location: Cell membrane; Single-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase S49 family [H]

Homologues:

Organism=Escherichia coli, GI1788064, Length=215, Percent_Identity=34.8837209302326, Blast_Score=106, Evalue=2e-24,
Organism=Escherichia coli, GI1787527, Length=174, Percent_Identity=29.8850574712644, Blast_Score=74, Evalue=1e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004635
- InterPro:   IPR002142 [H]

Pfam domain/function: PF01343 Peptidase_S49 [H]

EC number: 3.4.21.-

Molecular weight: Translated: 34134; Mature: 34134

Theoretical pI: Translated: 6.94; Mature: 6.94

Prosite motif: PS00013 PROKAR_LIPOPROTEIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRMIIAFLLGCLGMFLTTGCAFVSVPLMSAPQPLAEQVLEGEGTKKILIVDISGAIGDQA
CHHHHHHHHHHHHHHHHCCHHHHCCCCCCCCCHHHHHHHCCCCCCEEEEEEECCCCCCCC
KGGGLLSRGTPSTVSLVREVLLKAERDPKVAGLILRINSPGGTVTASDIIRHDLLAFKER
CCCCCCCCCCCHHHHHHHHHHHHCCCCCCEEEEEEEEECCCCCEEHHHHHHHHHHHHHHH
RNLPVSACIMGIGASGGYYVATAADGITAHPTALTGSIGVLLMTFNVEGLLGKVGVEEKT
CCCCHHHHHEEECCCCCEEEEEECCCCCCCCCEECCCCEEEEEEECCCHHHHCCCCCHHH
IKSGGKKDLLSPFRRATPEEERLVQGVIDQFHGRFVDVVQARPGNRLSRHDLLTLADGRI
HHCCCCHHHHHHHHHCCCHHHHHHHHHHHHHCCCEEEEEECCCCCCCCCCCEEEEECCCC
FSAADALAAGLIDRIGYLDDVIASLRDRIGDPDARVVTYFRPGSYQGSIYAESAAEPSMA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEECCCCCCCCEEECCCCCCCHH
DLLGGFDMTGGGQFMYLWRPW
HHHCCCCCCCCCEEEEEEECC
>Mature Secondary Structure
MRMIIAFLLGCLGMFLTTGCAFVSVPLMSAPQPLAEQVLEGEGTKKILIVDISGAIGDQA
CHHHHHHHHHHHHHHHHCCHHHHCCCCCCCCCHHHHHHHCCCCCCEEEEEEECCCCCCCC
KGGGLLSRGTPSTVSLVREVLLKAERDPKVAGLILRINSPGGTVTASDIIRHDLLAFKER
CCCCCCCCCCCHHHHHHHHHHHHCCCCCCEEEEEEEEECCCCCEEHHHHHHHHHHHHHHH
RNLPVSACIMGIGASGGYYVATAADGITAHPTALTGSIGVLLMTFNVEGLLGKVGVEEKT
CCCCHHHHHEEECCCCCEEEEEECCCCCCCCCEECCCCEEEEEEECCCHHHHCCCCCHHH
IKSGGKKDLLSPFRRATPEEERLVQGVIDQFHGRFVDVVQARPGNRLSRHDLLTLADGRI
HHCCCCHHHHHHHHHCCCHHHHHHHHHHHHHCCCEEEEEECCCCCCCCCCCEEEEECCCC
FSAADALAAGLIDRIGYLDDVIASLRDRIGDPDARVVTYFRPGSYQGSIYAESAAEPSMA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEECCCCCCCCEEECCCCCCCHH
DLLGGFDMTGGGQFMYLWRPW
HHHCCCCCCCCCEEEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: Hydrolase; Acting on peptide bonds (Peptidases) [C]

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 11058132 [H]