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The map label for this gene is fdhD [H]

Identifier: 39995886

GI number: 39995886

Start: 840072

End: 841508

Strand: Direct

Name: fdhD [H]

Synonym: GSU0780

Alternate gene names: 39995886

Gene position: 840072-841508 (Clockwise)

Preceding gene: 39995885

Following gene: 39995887

Centisome position: 22.03

GC content: 67.29

Gene sequence:

>1437_bases
ATGAAAACCATCCACATCTACACTAACGGCCGACTCGAAGAAAAGCGGGGCGATATCGTGCGGGAGTTTCCCCTGGTGCT
CCAGGTGAACGGCCGGGAGATCGCCACCCTCATCGCATCTCCCCACGACCTCCGCTTCCTGGTGGCCGGGTTCCTGCGCA
ACCAGGGCTTTGTCGAGTCGGCGGCGGATTTCCACATGCTGGCCGTCTGCGACGAGTTCGGCATCGCCAATGTCCGGATC
AGGCAGGAACTGCCCGAGCGGCTCAAGCCGGTCCTCACCAGTGGCTGCGGCACCGGCATCACCTTCACCCTGGAGACGGG
GGGGCGGGAAGCGGCCGTGGCGCCGTCGCCCGCCGTGGCACCGGAGGCGGTCTTCCGGCTCATGGAGGAACTGGCGCGGC
AGGCCGACAACTACCGGAACCACGGGGGCATCCACTCGGCCGCCGTGGGGGACGGGGAGGGGAACCTCCTCCTCTTTGCC
GAGGACATCGGCCGGCACAACACCCTCGACCGGATTGCCGGCGAGGCCCTGCTCAAGGGGATCGATCTGGCCGGCCGCAT
CCTGGTGACCTCGGGGCGCGTCTCCACGGAGATGGCCTCCAAGTGCGCCCGGCTCGGCATTGCCCTGGTGGCATCCCGCA
CTTCGGCCACCGATATGGCGGCGACTCTCTGCCACGAGGCGGGGATCTGCCTTCTGGGCTACGTGCGCGGCGGCAAGTTC
ACGGTCTATACCCACAGCGACCGGCTGCTGGTGCCGGAGCAGGCTGCGGCATCCCTGCCCGGGCCGGTGCCGCGGGGCCG
AATTCCCGGCGTCACCGGCGTCATCCTGGCCGGCGGCCAGTCCAGCCGCATGGGGAGCAACAAAGCCCTCCTCCCCTATC
GGGGCGGCCGTTTCATCGAGTCGATCCACCGCCAGCTCTCCGAGTATTTCGACGAGGTCATCGTCGTCACCAACACGCCG
GAGCAGTACGAATTCCTCCCTTGTCGGAAGGTGACCGACATCCACGAGGGAATGGGCGCCCTGGCCGGCATCCACGCCGG
TCTCCACCATAGTTCCAATCCGGCGGCCTTTGTGGTGGCCTGCGACATGCCCTATCTCAACGGCGACCTGATCCGCCACC
TGGCCTCTATGGCCGATCCCGGCGGGGTCCTGATCCCCGAGAGTCCCACGGGCCTGGAACCGCTCCACGCCGTGTACGGC
AAGGGGTGCCTCGCCGCGATCGAGGCGACGCTCCTCTCGGGCCAGCGACGGATCGTCTCGTTTTTCGGCAGGACCAATGT
CAATCGCGTCAATGTGGCCCAGATTGCCGCGTTCGACCCCGAGTTCAATTCGTTCCGCAACATCAACACACCGACCGACT
ACTACCGCCTGAGAGAGATCGAGCGCGGCGAGGCCCTGCCCGCCCCGGCCGACGAGCGGGCCGGGGCGTCGGCGTAA

Upstream 100 bases:

>100_bases
GATCGAGAAGCACGGCCACGGGACGGCGAGCGAAGCGTAGTTCACGTAATCCAACGGCGCAGGGGCAATTCATGGATTGC
CCCTGCAACCACGAGACCCC

Downstream 100 bases:

>100_bases
CGCTGTAATAAAAAGGAGACAGAACCATGTTCGGATTCGGCATGCCCGAAATGATCATTATCCTCGTCATCGCCCTGGTG
GTATTCGGCCCGGGGAAACT

Product: formate dehydrogenase accessory protein FdhD

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 478; Mature: 478

Protein sequence:

>478_residues
MKTIHIYTNGRLEEKRGDIVREFPLVLQVNGREIATLIASPHDLRFLVAGFLRNQGFVESAADFHMLAVCDEFGIANVRI
RQELPERLKPVLTSGCGTGITFTLETGGREAAVAPSPAVAPEAVFRLMEELARQADNYRNHGGIHSAAVGDGEGNLLLFA
EDIGRHNTLDRIAGEALLKGIDLAGRILVTSGRVSTEMASKCARLGIALVASRTSATDMAATLCHEAGICLLGYVRGGKF
TVYTHSDRLLVPEQAAASLPGPVPRGRIPGVTGVILAGGQSSRMGSNKALLPYRGGRFIESIHRQLSEYFDEVIVVTNTP
EQYEFLPCRKVTDIHEGMGALAGIHAGLHHSSNPAAFVVACDMPYLNGDLIRHLASMADPGGVLIPESPTGLEPLHAVYG
KGCLAAIEATLLSGQRRIVSFFGRTNVNRVNVAQIAAFDPEFNSFRNINTPTDYYRLREIERGEALPAPADERAGASA

Sequences:

>Translated_478_residues
MKTIHIYTNGRLEEKRGDIVREFPLVLQVNGREIATLIASPHDLRFLVAGFLRNQGFVESAADFHMLAVCDEFGIANVRI
RQELPERLKPVLTSGCGTGITFTLETGGREAAVAPSPAVAPEAVFRLMEELARQADNYRNHGGIHSAAVGDGEGNLLLFA
EDIGRHNTLDRIAGEALLKGIDLAGRILVTSGRVSTEMASKCARLGIALVASRTSATDMAATLCHEAGICLLGYVRGGKF
TVYTHSDRLLVPEQAAASLPGPVPRGRIPGVTGVILAGGQSSRMGSNKALLPYRGGRFIESIHRQLSEYFDEVIVVTNTP
EQYEFLPCRKVTDIHEGMGALAGIHAGLHHSSNPAAFVVACDMPYLNGDLIRHLASMADPGGVLIPESPTGLEPLHAVYG
KGCLAAIEATLLSGQRRIVSFFGRTNVNRVNVAQIAAFDPEFNSFRNINTPTDYYRLREIERGEALPAPADERAGASA
>Mature_478_residues
MKTIHIYTNGRLEEKRGDIVREFPLVLQVNGREIATLIASPHDLRFLVAGFLRNQGFVESAADFHMLAVCDEFGIANVRI
RQELPERLKPVLTSGCGTGITFTLETGGREAAVAPSPAVAPEAVFRLMEELARQADNYRNHGGIHSAAVGDGEGNLLLFA
EDIGRHNTLDRIAGEALLKGIDLAGRILVTSGRVSTEMASKCARLGIALVASRTSATDMAATLCHEAGICLLGYVRGGKF
TVYTHSDRLLVPEQAAASLPGPVPRGRIPGVTGVILAGGQSSRMGSNKALLPYRGGRFIESIHRQLSEYFDEVIVVTNTP
EQYEFLPCRKVTDIHEGMGALAGIHAGLHHSSNPAAFVVACDMPYLNGDLIRHLASMADPGGVLIPESPTGLEPLHAVYG
KGCLAAIEATLLSGQRRIVSFFGRTNVNRVNVAQIAAFDPEFNSFRNINTPTDYYRLREIERGEALPAPADERAGASA

Specific function: Necessary for formate dehydrogenase activity [H]

COG id: COG1526

COG function: function code C; Uncharacterized protein required for formate dehydrogenase activity

Gene ontology:

Cell location: Cytoplasm (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the fdhD family [H]

Homologues:

Organism=Escherichia coli, GI1790329, Length=261, Percent_Identity=27.9693486590038, Blast_Score=91, Evalue=2e-19,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003786 [H]

Pfam domain/function: PF02634 FdhD-NarQ [H]

EC number: NA

Molecular weight: Translated: 51366; Mature: 51366

Theoretical pI: Translated: 6.79; Mature: 6.79

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKTIHIYTNGRLEEKRGDIVREFPLVLQVNGREIATLIASPHDLRFLVAGFLRNQGFVES
CCEEEEEECCEECHHHCCHHHHCCEEEEECCCEEEEECCCCCHHHHHHHHHHHCCCCHHH
AADFHMLAVCDEFGIANVRIRQELPERLKPVLTSGCGTGITFTLETGGREAAVAPSPAVA
CCCEEEEEEECCCCCCCCHHHHHHHHHHHHHHHCCCCCCEEEEEECCCCEEECCCCCCCC
PEAVFRLMEELARQADNYRNHGGIHSAAVGDGEGNLLLFAEDIGRHNTLDRIAGEALLKG
HHHHHHHHHHHHHHHHCCCCCCCCEECEECCCCCCEEEEECCCCCCCHHHHHHHHHHHHH
IDLAGRILVTSGRVSTEMASKCARLGIALVASRTSATDMAATLCHEAGICLLGYVRGGKF
CCCCCEEEEECCCCHHHHHHHHHHHHHHEEECCCCHHHHHHHHHHHCCEEEEEEEECCEE
TVYTHSDRLLVPEQAAASLPGPVPRGRIPGVTGVILAGGQSSRMGSNKALLPYRGGRFIE
EEEECCCCEECCCHHHHCCCCCCCCCCCCCCCEEEEECCCCCCCCCCCEECCCCCCHHHH
SIHRQLSEYFDEVIVVTNTPEQYEFLPCRKVTDIHEGMGALAGIHAGLHHSSNPAAFVVA
HHHHHHHHHHCCEEEEECCCCCCEECCCCHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEE
CDMPYLNGDLIRHLASMADPGGVLIPESPTGLEPLHAVYGKGCLAAIEATLLSGQRRIVS
ECCCCCCHHHHHHHHHHCCCCCEEECCCCCCCCHHHHHHCCHHHHHHHHHHHCCCHHHHH
FFGRTNVNRVNVAQIAAFDPEFNSFRNINTPTDYYRLREIERGEALPAPADERAGASA
HHCCCCCCEEEEEEEEEECCCCCCCCCCCCCHHHHHHHHHHCCCCCCCCCCCCCCCCC
>Mature Secondary Structure
MKTIHIYTNGRLEEKRGDIVREFPLVLQVNGREIATLIASPHDLRFLVAGFLRNQGFVES
CCEEEEEECCEECHHHCCHHHHCCEEEEECCCEEEEECCCCCHHHHHHHHHHHCCCCHHH
AADFHMLAVCDEFGIANVRIRQELPERLKPVLTSGCGTGITFTLETGGREAAVAPSPAVA
CCCEEEEEEECCCCCCCCHHHHHHHHHHHHHHHCCCCCCEEEEEECCCCEEECCCCCCCC
PEAVFRLMEELARQADNYRNHGGIHSAAVGDGEGNLLLFAEDIGRHNTLDRIAGEALLKG
HHHHHHHHHHHHHHHHCCCCCCCCEECEECCCCCCEEEEECCCCCCCHHHHHHHHHHHHH
IDLAGRILVTSGRVSTEMASKCARLGIALVASRTSATDMAATLCHEAGICLLGYVRGGKF
CCCCCEEEEECCCCHHHHHHHHHHHHHHEEECCCCHHHHHHHHHHHCCEEEEEEEECCEE
TVYTHSDRLLVPEQAAASLPGPVPRGRIPGVTGVILAGGQSSRMGSNKALLPYRGGRFIE
EEEECCCCEECCCHHHHCCCCCCCCCCCCCCCEEEEECCCCCCCCCCCEECCCCCCHHHH
SIHRQLSEYFDEVIVVTNTPEQYEFLPCRKVTDIHEGMGALAGIHAGLHHSSNPAAFVVA
HHHHHHHHHHCCEEEEECCCCCCEECCCCHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEE
CDMPYLNGDLIRHLASMADPGGVLIPESPTGLEPLHAVYGKGCLAAIEATLLSGQRRIVS
ECCCCCCHHHHHHHHHHCCCCCEEECCCCCCCCHHHHHHCCHHHHHHHHHHHCCCHHHHH
FFGRTNVNRVNVAQIAAFDPEFNSFRNINTPTDYYRLREIERGEALPAPADERAGASA
HHCCCCCCEEEEEEEEEECCCCCCCCCCCCCHHHHHHHHHHCCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 7860592; 9384377 [H]