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The map label for this gene is dhaR [H]

Identifier: 39995876

GI number: 39995876

Start: 826391

End: 826981

Strand: Direct

Name: dhaR [H]

Synonym: GSU0770

Alternate gene names: 39995876

Gene position: 826391-826981 (Clockwise)

Preceding gene: 39995874

Following gene: 39995877

Centisome position: 21.67

GC content: 64.47

Gene sequence:

>591_bases
ATGGACAAGAACGAAACGCGCGCCACGATCATTCGCATCGGCACCGATCTCATCTCCCGCCAGGGATTCAACGCCACCGG
CATCGACGCGGTGCTGAAGGAGGCGGGGGTCCCCAAGGGTTCCTTTTACTATTATTTCAGGAGCAAGGAGGAGTTCGGCC
TGGCGGTGATCGACCATTTCGCCGAACGCTACGACCAGCGGCTCGACACCTTCCTGAACGACGAGGAGGTGACGCCGCTG
AACCGCATCCGCAACTACCTGGAGAGCGCGCTGGCGCGGCTGGAGCAGAACCAGTGCAGCAAGGGATGCCTCATCGGCAA
CCTGGGCCAGGAACTGGCCGACCAGCACGAGCGGTTCCGGGGGCGGCTCGACGAGATTTTTCGTTCCTGGAAGGATCGTT
TCGCCGCCTGCCTGCGGGAAGCCCAGCGGGGGGGGGAGCTGGCCCCGGAGCTCGATGCCGGGGTGGCGGCGGGGTTCATC
CTCTCGGGCCTGGAGGGGGCGATCCTGCGGACCAAGGTGATGAAGTCGCCCCAGCCGCTGCGGGATTTCATCGAAATACT
CTTCGCTTCGGTGCTGCGCCGACAGGCGTGA

Upstream 100 bases:

>100_bases
TACAGATTGGGGCAGCTAACAACTGTACTGTTATGAAAAGAAGTAAACTGTTCCGGGAACGGACTTGACTTTCTAGACGA
CCGGTCTAATAATCTCTCCC

Downstream 100 bases:

>100_bases
CAGCGATTTCAAACAACTAGGCGATCGGTCTAGCGGTTTCACGCCCTGTCGGCCGGCGGGGCGCATGGATACGGGATGCG
AGCCGTAGAGGTTACTAAGA

Product: TetR family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 196; Mature: 196

Protein sequence:

>196_residues
MDKNETRATIIRIGTDLISRQGFNATGIDAVLKEAGVPKGSFYYYFRSKEEFGLAVIDHFAERYDQRLDTFLNDEEVTPL
NRIRNYLESALARLEQNQCSKGCLIGNLGQELADQHERFRGRLDEIFRSWKDRFAACLREAQRGGELAPELDAGVAAGFI
LSGLEGAILRTKVMKSPQPLRDFIEILFASVLRRQA

Sequences:

>Translated_196_residues
MDKNETRATIIRIGTDLISRQGFNATGIDAVLKEAGVPKGSFYYYFRSKEEFGLAVIDHFAERYDQRLDTFLNDEEVTPL
NRIRNYLESALARLEQNQCSKGCLIGNLGQELADQHERFRGRLDEIFRSWKDRFAACLREAQRGGELAPELDAGVAAGFI
LSGLEGAILRTKVMKSPQPLRDFIEILFASVLRRQA
>Mature_196_residues
MDKNETRATIIRIGTDLISRQGFNATGIDAVLKEAGVPKGSFYYYFRSKEEFGLAVIDHFAERYDQRLDTFLNDEEVTPL
NRIRNYLESALARLEQNQCSKGCLIGNLGQELADQHERFRGRLDEIFRSWKDRFAACLREAQRGGELAPELDAGVAAGFI
LSGLEGAILRTKVMKSPQPLRDFIEILFASVLRRQA

Specific function: Transcriptional repressor for the dhaA haloalkane dehalogenase gene [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH tetR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI145693141, Length=184, Percent_Identity=32.6086956521739, Blast_Score=90, Evalue=1e-19,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR009057
- InterPro:   IPR015893
- InterPro:   IPR011075
- InterPro:   IPR001647 [H]

Pfam domain/function: PF00440 TetR_N [H]

EC number: NA

Molecular weight: Translated: 22205; Mature: 22205

Theoretical pI: Translated: 6.54; Mature: 6.54

Prosite motif: PS50977 HTH_TETR_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
1.0 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
1.0 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDKNETRATIIRIGTDLISRQGFNATGIDAVLKEAGVPKGSFYYYFRSKEEFGLAVIDHF
CCCCHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHCCCCCCEEEEEECCCHHHHHHHHHH
AERYDQRLDTFLNDEEVTPLNRIRNYLESALARLEQNQCSKGCLIGNLGQELADQHERFR
HHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCEEHHHHHHHHHHHHHHH
GRLDEIFRSWKDRFAACLREAQRGGELAPELDAGVAAGFILSGLEGAILRTKVMKSPQPL
HHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCH
RDFIEILFASVLRRQA
HHHHHHHHHHHHHHCC
>Mature Secondary Structure
MDKNETRATIIRIGTDLISRQGFNATGIDAVLKEAGVPKGSFYYYFRSKEEFGLAVIDHF
CCCCHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHCCCCCCEEEEEECCCHHHHHHHHHH
AERYDQRLDTFLNDEEVTPLNRIRNYLESALARLEQNQCSKGCLIGNLGQELADQHERFR
HHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCEEHHHHHHHHHHHHHHH
GRLDEIFRSWKDRFAACLREAQRGGELAPELDAGVAAGFILSGLEGAILRTKVMKSPQPL
HHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCH
RDFIEILFASVLRRQA
HHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10735862 [H]