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The map label for this gene is nreC [H]

Identifier: 39995788

GI number: 39995788

Start: 718009

End: 718656

Strand: Direct

Name: nreC [H]

Synonym: GSU0682

Alternate gene names: 39995788

Gene position: 718009-718656 (Clockwise)

Preceding gene: 39995787

Following gene: 39995789

Centisome position: 18.82

GC content: 61.11

Gene sequence:

>648_bases
ATGCTGCGGGTACTGCTGGTCGATGACCACCGGATCGTGCTGGAGGGGCTGCGGGCCCTCGTGAGCGAGCATTCCGACCT
GGAGGTCGTCGGGGTCGCGTGCGACGGGGCAACGGCCATCGAGCTCACCCGACAGCTGCGGCCTGACGTGGTGGTGATGG
ACATAACGATGCCCGGCATGAACGGCATTGAGGCGACCCGGCGCATCGTGGCGGAATTCCCCCGCACCCGGGTTCTTATC
CTGTCCATGGAGTCGGAGCGGCGGTTTGTCCTCGAGGTCCTCAAGACCGGTGCCCACGGCTATCTGCTGAAGGACTGCAG
CCAGGACGAGCTGGTTTCGGCAATTCGTCACGTGGCGGGGGGCGAACCCTACCTTGGGCCCCGTATCACCGAGATGATCA
TTCGAGCCTACATGGAACGGATTCCTGATGATACACTCCTGACCCATACCCTTCTATCCCTCCGCGAACGAGAGGTGCTG
CAGCTGATTGCCGCCGGGAAGAGCACAAAAGAGATCGCCTTTGCCTTCGGGGTGAGCCTCAAAACCATCGAGACCCAGCG
TCACAGCATCATGAAAAAGCTCAACCTTTACAGTGTCGCGGAACTTACCAAGTATGCCATTCGCGAAGGGCTCACCCCGC
TCCGCTGA

Upstream 100 bases:

>100_bases
CGGTCCAGTCGGAACCAGGCTGCGGCACCCGTACGGTCATCCGCGTTCCGCTGAAAGGGGAACAGCACGGTACGACTCAT
GCCGAAAGTGGAGCGCAATG

Downstream 100 bases:

>100_bases
CCAGAGTCGCCTCTTCTCCTCACCCCTGCTTTGGGGTTTTTCGAAATCTCACCTCGCAATCCGCTGATAGAGAAATCATT
CCCCCAATCCGAATACAATA

Product: LuxR family transcriptional regulator

Products: NA

Alternate protein names: Nitrogen regulation protein C [H]

Number of amino acids: Translated: 215; Mature: 215

Protein sequence:

>215_residues
MLRVLLVDDHRIVLEGLRALVSEHSDLEVVGVACDGATAIELTRQLRPDVVVMDITMPGMNGIEATRRIVAEFPRTRVLI
LSMESERRFVLEVLKTGAHGYLLKDCSQDELVSAIRHVAGGEPYLGPRITEMIIRAYMERIPDDTLLTHTLLSLREREVL
QLIAAGKSTKEIAFAFGVSLKTIETQRHSIMKKLNLYSVAELTKYAIREGLTPLR

Sequences:

>Translated_215_residues
MLRVLLVDDHRIVLEGLRALVSEHSDLEVVGVACDGATAIELTRQLRPDVVVMDITMPGMNGIEATRRIVAEFPRTRVLI
LSMESERRFVLEVLKTGAHGYLLKDCSQDELVSAIRHVAGGEPYLGPRITEMIIRAYMERIPDDTLLTHTLLSLREREVL
QLIAAGKSTKEIAFAFGVSLKTIETQRHSIMKKLNLYSVAELTKYAIREGLTPLR
>Mature_215_residues
MLRVLLVDDHRIVLEGLRALVSEHSDLEVVGVACDGATAIELTRQLRPDVVVMDITMPGMNGIEATRRIVAEFPRTRVLI
LSMESERRFVLEVLKTGAHGYLLKDCSQDELVSAIRHVAGGEPYLGPRITEMIIRAYMERIPDDTLLTHTLLSLREREVL
QLIAAGKSTKEIAFAFGVSLKTIETQRHSIMKKLNLYSVAELTKYAIREGLTPLR

Specific function: Member of the two-component regulatory system nreB/nreC involved in the control of dissimilatory nitrate/nitrite reduction in response to oxygen. Phosphorylated nreC binds to a GC-rich palindromic sequence at the promoters of the nitrate (narGHJI) and nit

COG id: COG2197

COG function: function code TK; Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain

Gene ontology:

Cell location: Cytoplasm (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI1788222, Length=211, Percent_Identity=36.4928909952607, Blast_Score=139, Evalue=1e-34,
Organism=Escherichia coli, GI1788521, Length=197, Percent_Identity=31.9796954314721, Blast_Score=105, Evalue=3e-24,
Organism=Escherichia coli, GI1790102, Length=205, Percent_Identity=34.6341463414634, Blast_Score=100, Evalue=1e-22,
Organism=Escherichia coli, GI1787473, Length=187, Percent_Identity=34.7593582887701, Blast_Score=94, Evalue=5e-21,
Organism=Escherichia coli, GI1786747, Length=203, Percent_Identity=30.0492610837438, Blast_Score=93, Evalue=1e-20,
Organism=Escherichia coli, GI1788712, Length=208, Percent_Identity=24.0384615384615, Blast_Score=85, Evalue=3e-18,
Organism=Escherichia coli, GI1788546, Length=215, Percent_Identity=28.3720930232558, Blast_Score=78, Evalue=4e-16,
Organism=Escherichia coli, GI87082052, Length=104, Percent_Identity=33.6538461538462, Blast_Score=65, Evalue=2e-12,
Organism=Escherichia coli, GI1788550, Length=111, Percent_Identity=35.1351351351351, Blast_Score=65, Evalue=5e-12,
Organism=Escherichia coli, GI1789937, Length=197, Percent_Identity=24.8730964467005, Blast_Score=64, Evalue=9e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011006
- InterPro:   IPR016032
- InterPro:   IPR001789
- InterPro:   IPR000792
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00196 GerE; PF00072 Response_reg [H]

EC number: NA

Molecular weight: Translated: 24118; Mature: 24118

Theoretical pI: Translated: 7.15; Mature: 7.15

Prosite motif: PS50110 RESPONSE_REGULATORY ; PS00622 HTH_LUXR_1 ; PS50043 HTH_LUXR_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
3.7 %Met     (Translated Protein)
4.7 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
3.7 %Met     (Mature Protein)
4.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLRVLLVDDHRIVLEGLRALVSEHSDLEVVGVACDGATAIELTRQLRPDVVVMDITMPGM
CEEEEEECCCHHHHHHHHHHHCCCCCCEEEEEECCCHHHHHHHHHCCCCEEEEEEECCCC
NGIEATRRIVAEFPRTRVLILSMESERRFVLEVLKTGAHGYLLKDCSQDELVSAIRHVAG
CHHHHHHHHHHHCCCCEEEEEEECCCHHHHHHHHHCCCCCEEECCCCHHHHHHHHHHHCC
GEPYLGPRITEMIIRAYMERIPDDTLLTHTLLSLREREVLQLIAAGKSTKEIAFAFGVSL
CCCCCCHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHCCCH
KTIETQRHSIMKKLNLYSVAELTKYAIREGLTPLR
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCC
>Mature Secondary Structure
MLRVLLVDDHRIVLEGLRALVSEHSDLEVVGVACDGATAIELTRQLRPDVVVMDITMPGM
CEEEEEECCCHHHHHHHHHHHCCCCCCEEEEEECCCHHHHHHHHHCCCCEEEEEEECCCC
NGIEATRRIVAEFPRTRVLILSMESERRFVLEVLKTGAHGYLLKDCSQDELVSAIRHVAG
CHHHHHHHHHHHCCCCEEEEEEECCCHHHHHHHHHCCCCCEEECCCCHHHHHHHHHHHCC
GEPYLGPRITEMIIRAYMERIPDDTLLTHTLLSLREREVLQLIAAGKSTKEIAFAFGVSL
CCCCCCHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHCCCH
KTIETQRHSIMKKLNLYSVAELTKYAIREGLTPLR
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12426351 [H]