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The map label for this gene is nreB [H]

Identifier: 39995787

GI number: 39995787

Start: 716939

End: 718009

Strand: Direct

Name: nreB [H]

Synonym: GSU0681

Alternate gene names: 39995787

Gene position: 716939-718009 (Clockwise)

Preceding gene: 39995786

Following gene: 39995788

Centisome position: 18.8

GC content: 59.85

Gene sequence:

>1071_bases
ATGCTGTCAGTGCTCCGAGACAACATTTTCAGCCTGTTCATGCAGCATCTTCCCGGGGTTTCCTTTATCAAGGACCTTGC
CGGACACTACCTCTATGCCAATGATCAGTGGAAGCGGCTTGTATCGTCGGACACCGCCGAAGACCGACCTGGAGGTCCTG
ACGGGGGGCAGTTCGAAGAGAACGACCAACGGGTCATTACGGAAGCGGCCGGCATCCAGACCGTGGAAACGGTTCAGGCC
GAGGACGGTGTGCACCACTGGATCATGAGCGAGTTCCCGATCCGTGACGAGCAGGGTGAAGTCGTTCTGCTCGGCGGGAT
CGGGCTCGACATTACGCGTCGTTTGCGTCTTGAGGAAGAGCTGAATATCTACCGGGAGCGGCTTGCGTCCCTTGCGGTGG
AGCTTGCTGTTGCCGAAGACCGTGAGCGCAGCCGCATCGCGGGCGAGCTTCACGATCAGGTGGGGCAGAATCTTTTCCTG
GCGGGGCTCAAGCTTGGTTCGTTGAAGATTTCCTCTCTCGGCGATGATGACCGCCGCGTGGTGGAAGAGATCAGGCATCT
GATCGGTGGTGCCCTGCAGGATATCCGTTCACTGACCTGTCAGCTCCGGCCGCCGCTCCTTGCCCATGGGGGGCTGGTTG
CAGCTCTTTGCTGGCTGGGGGAGCAATTTCGGGAAGACTTCGGGCTGCAGGTGGACATCTTTGATGACCAGCATGAGAAG
CCGCTCTCGCCCGAGGTCAGTTCGACGCTCTTTCAGGTTGTCAGGGAACTGTTGCTGAACACCGCAAAGCATGCGTCGGC
ACCGCGGGCGGCCATATCCGTCACGACGGAGGCCGACTCCATCATGGTAAGCGTTGAAGACGGGGGCGTGGGGTTTGACG
TCTCCTCCGTGAGCCTTAACTGCGGCAAGAGCGGCGGTTTTGGTCTCTTCAACGCTCGGCAGAAAATAGAGTACCTGGGC
GGGACGCTGACGGTCCAGTCGGAACCAGGCTGCGGCACCCGTACGGTCATCCGCGTTCCGCTGAAAGGGGAACAGCACGG
TACGACTCATGCCGAAAGTGGAGCGCAATGA

Upstream 100 bases:

>100_bases
TTTATTCGCATTTGGATGATTTACGACCAGTCGTGCGTTGTTTCATAGTGCAATATTGACAACTCTATATTTTACGATAT
TGCGGGGGCGCGCAAAGCCA

Downstream 100 bases:

>100_bases
TGCTGCGGGTACTGCTGGTCGATGACCACCGGATCGTGCTGGAGGGGCTGCGGGCCCTCGTGAGCGAGCATTCCGACCTG
GAGGTCGTCGGGGTCGCGTG

Product: sensory box histidine kinase

Products: NA

Alternate protein names: Nitrogen regulation protein B [H]

Number of amino acids: Translated: 356; Mature: 356

Protein sequence:

>356_residues
MLSVLRDNIFSLFMQHLPGVSFIKDLAGHYLYANDQWKRLVSSDTAEDRPGGPDGGQFEENDQRVITEAAGIQTVETVQA
EDGVHHWIMSEFPIRDEQGEVVLLGGIGLDITRRLRLEEELNIYRERLASLAVELAVAEDRERSRIAGELHDQVGQNLFL
AGLKLGSLKISSLGDDDRRVVEEIRHLIGGALQDIRSLTCQLRPPLLAHGGLVAALCWLGEQFREDFGLQVDIFDDQHEK
PLSPEVSSTLFQVVRELLLNTAKHASAPRAAISVTTEADSIMVSVEDGGVGFDVSSVSLNCGKSGGFGLFNARQKIEYLG
GTLTVQSEPGCGTRTVIRVPLKGEQHGTTHAESGAQ

Sequences:

>Translated_356_residues
MLSVLRDNIFSLFMQHLPGVSFIKDLAGHYLYANDQWKRLVSSDTAEDRPGGPDGGQFEENDQRVITEAAGIQTVETVQA
EDGVHHWIMSEFPIRDEQGEVVLLGGIGLDITRRLRLEEELNIYRERLASLAVELAVAEDRERSRIAGELHDQVGQNLFL
AGLKLGSLKISSLGDDDRRVVEEIRHLIGGALQDIRSLTCQLRPPLLAHGGLVAALCWLGEQFREDFGLQVDIFDDQHEK
PLSPEVSSTLFQVVRELLLNTAKHASAPRAAISVTTEADSIMVSVEDGGVGFDVSSVSLNCGKSGGFGLFNARQKIEYLG
GTLTVQSEPGCGTRTVIRVPLKGEQHGTTHAESGAQ
>Mature_356_residues
MLSVLRDNIFSLFMQHLPGVSFIKDLAGHYLYANDQWKRLVSSDTAEDRPGGPDGGQFEENDQRVITEAAGIQTVETVQA
EDGVHHWIMSEFPIRDEQGEVVLLGGIGLDITRRLRLEEELNIYRERLASLAVELAVAEDRERSRIAGELHDQVGQNLFL
AGLKLGSLKISSLGDDDRRVVEEIRHLIGGALQDIRSLTCQLRPPLLAHGGLVAALCWLGEQFREDFGLQVDIFDDQHEK
PLSPEVSSTLFQVVRELLLNTAKHASAPRAAISVTTEADSIMVSVEDGGVGFDVSSVSLNCGKSGGFGLFNARQKIEYLG
GTLTVQSEPGCGTRTVIRVPLKGEQHGTTHAESGAQ

Specific function: Member of the two-component regulatory system nreB/nreC involved in the control of dissimilatory nitrate/nitrite reduction in response to oxygen. NreB functions as a direct oxygen sensor histidine kinase which is autophosphorylated, in the absence of oxyg

COG id: COG4585

COG function: function code T; Signal transduction histidine kinase

Gene ontology:

Cell location: Cytoplasm (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 histidine kinase domain [H]

Homologues:

Organism=Escherichia coli, GI1787474, Length=215, Percent_Identity=28.3720930232558, Blast_Score=75, Evalue=9e-15,
Organism=Escherichia coli, GI1788812, Length=200, Percent_Identity=28.5, Blast_Score=64, Evalue=1e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR004358
- InterPro:   IPR011712
- InterPro:   IPR005467
- InterPro:   IPR017203 [H]

Pfam domain/function: PF02518 HATPase_c; PF07730 HisKA_3 [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 38901; Mature: 38901

Theoretical pI: Translated: 4.70; Mature: 4.70

Prosite motif: PS50113 PAC ; PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
1.1 %Met     (Translated Protein)
2.2 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
1.1 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLSVLRDNIFSLFMQHLPGVSFIKDLAGHYLYANDQWKRLVSSDTAEDRPGGPDGGQFEE
CCHHHHHHHHHHHHHHCCCHHHHHHHHCCEEEECHHHHHHHHCCCCCCCCCCCCCCCCCC
NDQRVITEAAGIQTVETVQAEDGVHHWIMSEFPIRDEQGEVVLLGGIGLDITRRLRLEEE
CCHHHHHHHCCCHHHHHHHHCCCHHHHHHCCCCCCCCCCCEEEEECCCCCHHHHHHHHHH
LNIYRERLASLAVELAVAEDRERSRIAGELHDQVGQNLFLAGLKLGSLKISSLGDDDRRV
HHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHCCCEEEECEEECCEEECCCCCHHHHH
VEEIRHLIGGALQDIRSLTCQLRPPLLAHGGLVAALCWLGEQFREDFGLQVDIFDDQHEK
HHHHHHHHHHHHHHHHHHHHHCCCCHHHHCHHHHHHHHHHHHHHHHCCCEEEEECCCCCC
PLSPEVSSTLFQVVRELLLNTAKHASAPRAAISVTTEADSIMVSVEDGGVGFDVSSVSLN
CCCCHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEEECCCEEEEEEECCCCCEEEEEEEEE
CGKSGGFGLFNARQKIEYLGGTLTVQSEPGCGTRTVIRVPLKGEQHGTTHAESGAQ
CCCCCCCCCHHHHHHHHHCCCEEEEECCCCCCCEEEEEEECCCCCCCCCCCCCCCC
>Mature Secondary Structure
MLSVLRDNIFSLFMQHLPGVSFIKDLAGHYLYANDQWKRLVSSDTAEDRPGGPDGGQFEE
CCHHHHHHHHHHHHHHCCCHHHHHHHHCCEEEECHHHHHHHHCCCCCCCCCCCCCCCCCC
NDQRVITEAAGIQTVETVQAEDGVHHWIMSEFPIRDEQGEVVLLGGIGLDITRRLRLEEE
CCHHHHHHHCCCHHHHHHHHCCCHHHHHHCCCCCCCCCCCEEEEECCCCCHHHHHHHHHH
LNIYRERLASLAVELAVAEDRERSRIAGELHDQVGQNLFLAGLKLGSLKISSLGDDDRRV
HHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHCCCEEEECEEECCEEECCCCCHHHHH
VEEIRHLIGGALQDIRSLTCQLRPPLLAHGGLVAALCWLGEQFREDFGLQVDIFDDQHEK
HHHHHHHHHHHHHHHHHHHHHCCCCHHHHCHHHHHHHHHHHHHHHHCCCEEEEECCCCCC
PLSPEVSSTLFQVVRELLLNTAKHASAPRAAISVTTEADSIMVSVEDGGVGFDVSSVSLN
CCCCHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEEECCCEEEEEEECCCCCEEEEEEEEE
CGKSGGFGLFNARQKIEYLGGTLTVQSEPGCGTRTVIRVPLKGEQHGTTHAESGAQ
CCCCCCCCCHHHHHHHHHCCCEEEEECCCCCCCEEEEEEECCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA