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The map label for this gene is lolE [C]

Identifier: 39995783

GI number: 39995783

Start: 710364

End: 711527

Strand: Direct

Name: lolE [C]

Synonym: GSU0677

Alternate gene names: 39995783

Gene position: 710364-711527 (Clockwise)

Preceding gene: 39995782

Following gene: 39995784

Centisome position: 18.62

GC content: 65.12

Gene sequence:

>1164_bases
ATGAACATCACGAAACTGGTGGTTAAGAACATCACCCGCCGGCGGGGGAGGTTCGTGTTCACCCTTCTGGGCATCACCAT
CGGCATCGCCTCCTTTGTGGCATTTCTGGCCCTGGGGGGCGGGCTCAAGGATGAGGTGCGGCGCGAGGCGGCCGCCCTGG
GGGCGAACCTGGTGGTGACCCCCAAAGGGTCGTGCGCCTATGAGCAGGTATCGATTCTCACCGGCGAGCAGCTTCCCTCA
ACCATCACCATGGAGGAGGTGGGCCGGGTCGCGGCCATCCAGGGGCTCACGGCGGTGCCGGTCCTGACCGAGAAGACCGC
CATCCGGAACCGTCCCGTGGGGGTGGCCGGCGTTCTTCCCGACGCCATGAAGCCGTTCAAGGGGTGGGAGGTGCGCAGCG
GAGAGTATTTCGCGAATAATGACGAGCGGGTCGTGGTGGTCGGCGCGGCCGCGGCTGAATCCTTCGGCCTCAAGCCCGGC
GACGAGGTTACCATCCGCGGGACGCGGCTGCCGGTGAAGGGGGTGTTGAAGGAGACCGGCAGCAAGGACGACACCACCCT
GTTCCTGGCCCTCTCCGTGGCCCAGGAGCTCTTCAAGGCCGCCGGCAAGGCGTCGTTCGTGGCGGTGAAGGTGGACGACC
TCTCCCGGACCGACGACTACATCATGAAGATCAAGGAAACGGTGAACGCGGGGGTCGTGTCGGACAAGCAGATGCTCAAG
TCGGTCCTGGGCATCATCGGCACGGTGAATGTGACGCTTCAGTTGATCGCCGCGATATCGGTGCTGGCCGCGGCCTTCGG
CATCGTCAATACCATGATGACCGCCACCTACGAGCGGCGTCGTGAGATCGGCATCCTCCAGGCCATCGGGGCGCGACGCA
GGGAAATATTCGCCATTTTTCTCATGGAGTCCGGATTCTACGGCCTCCTGGGCGGCATCTGCGGCGTCGCGGGAGGCCTG
GCGGCGTCGATCCTGGTCGGGCCCATGGTAAATCAGAATGCCTTCCTGGCCTTCGTGAAGGGCAATGACCCTGCGGCGGT
CCTGGACCCGAAGCTCATGGTCGGCTCAGTGGCCTTCTCGGTGGCGGTTGCCCTGGTGGCCGGGCTCTATCCCGCGTGGC
GCGCCGCGCGGCTCACCCCAGTGGAGGCGATCAGCCATGAGTGA

Upstream 100 bases:

>100_bases
CGAGGTGCGGGTGACCGGCAGCTTCCGGACCGAGCCGGGCGGTCTCATCTTTGTGGCCGAAAAGATGAAGGTGGTGAAGA
ACCACAAGATCGGAGGGTAG

Downstream 100 bases:

>100_bases
CGCAATCATCCGGACGGAAAACCTGACCAAAACGTACGGCTCCGGCCAGGTCACCACCCACGCCCTGCGGGGAGTGAGCC
TGGAGATCCCGCGCGGCGCG

Product: ABC transporter permease

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 387; Mature: 387

Protein sequence:

>387_residues
MNITKLVVKNITRRRGRFVFTLLGITIGIASFVAFLALGGGLKDEVRREAAALGANLVVTPKGSCAYEQVSILTGEQLPS
TITMEEVGRVAAIQGLTAVPVLTEKTAIRNRPVGVAGVLPDAMKPFKGWEVRSGEYFANNDERVVVVGAAAAESFGLKPG
DEVTIRGTRLPVKGVLKETGSKDDTTLFLALSVAQELFKAAGKASFVAVKVDDLSRTDDYIMKIKETVNAGVVSDKQMLK
SVLGIIGTVNVTLQLIAAISVLAAAFGIVNTMMTATYERRREIGILQAIGARRREIFAIFLMESGFYGLLGGICGVAGGL
AASILVGPMVNQNAFLAFVKGNDPAAVLDPKLMVGSVAFSVAVALVAGLYPAWRAARLTPVEAISHE

Sequences:

>Translated_387_residues
MNITKLVVKNITRRRGRFVFTLLGITIGIASFVAFLALGGGLKDEVRREAAALGANLVVTPKGSCAYEQVSILTGEQLPS
TITMEEVGRVAAIQGLTAVPVLTEKTAIRNRPVGVAGVLPDAMKPFKGWEVRSGEYFANNDERVVVVGAAAAESFGLKPG
DEVTIRGTRLPVKGVLKETGSKDDTTLFLALSVAQELFKAAGKASFVAVKVDDLSRTDDYIMKIKETVNAGVVSDKQMLK
SVLGIIGTVNVTLQLIAAISVLAAAFGIVNTMMTATYERRREIGILQAIGARRREIFAIFLMESGFYGLLGGICGVAGGL
AASILVGPMVNQNAFLAFVKGNDPAAVLDPKLMVGSVAFSVAVALVAGLYPAWRAARLTPVEAISHE
>Mature_387_residues
MNITKLVVKNITRRRGRFVFTLLGITIGIASFVAFLALGGGLKDEVRREAAALGANLVVTPKGSCAYEQVSILTGEQLPS
TITMEEVGRVAAIQGLTAVPVLTEKTAIRNRPVGVAGVLPDAMKPFKGWEVRSGEYFANNDERVVVVGAAAAESFGLKPG
DEVTIRGTRLPVKGVLKETGSKDDTTLFLALSVAQELFKAAGKASFVAVKVDDLSRTDDYIMKIKETVNAGVVSDKQMLK
SVLGIIGTVNVTLQLIAAISVLAAAFGIVNTMMTATYERRREIGILQAIGARRREIFAIFLMESGFYGLLGGICGVAGGL
AASILVGPMVNQNAFLAFVKGNDPAAVLDPKLMVGSVAFSVAVALVAGLYPAWRAARLTPVEAISHE

Specific function: Part Of An ATP-Dependent Transport System Lolcde Responsible For The Release Of Lipoproteins Targeted To The Outer Membrane From The Inner Membrane. Such A Release Is Dependent Of The Sorting-Signal (Absence Of An Asp At Position 2 Of The Mature Lipoprot

COG id: COG0577

COG function: function code V; ABC-type antimicrobial peptide transport system, permease component

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ABC-4 integral membrane protein family [H]

Homologues:

Organism=Escherichia coli, GI1787362, Length=342, Percent_Identity=25.1461988304094, Blast_Score=87, Evalue=2e-18,
Organism=Escherichia coli, GI1787360, Length=408, Percent_Identity=25, Blast_Score=67, Evalue=2e-12,
Organism=Escherichia coli, GI1787105, Length=398, Percent_Identity=26.1306532663317, Blast_Score=64, Evalue=2e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003838 [H]

Pfam domain/function: PF02687 FtsX [H]

EC number: NA

Molecular weight: Translated: 40853; Mature: 40853

Theoretical pI: Translated: 9.96; Mature: 9.96

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNITKLVVKNITRRRGRFVFTLLGITIGIASFVAFLALGGGLKDEVRREAAALGANLVVT
CCHHHHHHHHHHHHCCCEEHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCEEEE
PKGSCAYEQVSILTGEQLPSTITMEEVGRVAAIQGLTAVPVLTEKTAIRNRPVGVAGVLP
CCCCCCHHHHHEEECCCCCCEECHHHHCHHHHHCCCEECCEECCHHHHCCCCCCEEECCC
DAMKPFKGWEVRSGEYFANNDERVVVVGAAAAESFGLKPGDEVTIRGTRLPVKGVLKETG
HHHCCCCCCEECCCCEEECCCCEEEEEEECHHHHCCCCCCCEEEEEECCCCHHHHHHHCC
SKDDTTLFLALSVAQELFKAAGKASFVAVKVDDLSRTDDYIMKIKETVNAGVVSDKQMLK
CCCCCEEEHHHHHHHHHHHHCCCCEEEEEEECCCCCCHHHHHHHHHHHCCCCCCHHHHHH
SVLGIIGTVNVTLQLIAAISVLAAAFGIVNTMMTATYERRREIGILQAIGARRREIFAIF
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHEEEEE
LMESGFYGLLGGICGVAGGLAASILVGPMVNQNAFLAFVKGNDPAAVLDPKLMVGSVAFS
EECCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEEECCCCCEEECCHHHHHHHHHH
VAVALVAGLYPAWRAARLTPVEAISHE
HHHHHHHHCCHHHHHCCCCHHHHHCCC
>Mature Secondary Structure
MNITKLVVKNITRRRGRFVFTLLGITIGIASFVAFLALGGGLKDEVRREAAALGANLVVT
CCHHHHHHHHHHHHCCCEEHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCEEEE
PKGSCAYEQVSILTGEQLPSTITMEEVGRVAAIQGLTAVPVLTEKTAIRNRPVGVAGVLP
CCCCCCHHHHHEEECCCCCCEECHHHHCHHHHHCCCEECCEECCHHHHCCCCCCEEECCC
DAMKPFKGWEVRSGEYFANNDERVVVVGAAAAESFGLKPGDEVTIRGTRLPVKGVLKETG
HHHCCCCCCEECCCCEEECCCCEEEEEEECHHHHCCCCCCCEEEEEECCCCHHHHHHHCC
SKDDTTLFLALSVAQELFKAAGKASFVAVKVDDLSRTDDYIMKIKETVNAGVVSDKQMLK
CCCCCEEEHHHHHHHHHHHHCCCCEEEEEEECCCCCCHHHHHHHHHHHCCCCCCHHHHHH
SVLGIIGTVNVTLQLIAAISVLAAAFGIVNTMMTATYERRREIGILQAIGARRREIFAIF
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHEEEEE
LMESGFYGLLGGICGVAGGLAASILVGPMVNQNAFLAFVKGNDPAAVLDPKLMVGSVAFS
EECCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEEECCCCCEEECCHHHHHHHHHH
VAVALVAGLYPAWRAARLTPVEAISHE
HHHHHHHHCCHHHHHCCCCHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8688087 [H]