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The map label for this gene is glyQ

Identifier: 39995685

GI number: 39995685

Start: 607314

End: 608192

Strand: Direct

Name: glyQ

Synonym: GSU0578

Alternate gene names: 39995685

Gene position: 607314-608192 (Clockwise)

Preceding gene: 39995684

Following gene: 39995686

Centisome position: 15.92

GC content: 62.46

Gene sequence:

>879_bases
TTGACCTTCCAGGATCTGATTCTCGCCCTCCAGGGATACTGGGCACAGCAGGGATGCGTCATCCAGCAGCCCTACGACAC
CGAAAAGGGTGCCGGTACCTTCAACCCCGCCACCTTCCTTCGCGTTCTCGGCCCCGAGCCGTGGAACGTCGCCTACGTGG
AGCCGTCCCGCCGTCCCACCGACGGGCGCTACGGTGAAAACCCCAACCGCCTCCAGCACTACTACCAGTTCCAGGTGATC
ATGAAGCCGTCCCCCATGAATATCCTGGATCTCTATCTGGATTCGCTCCGGGCCTTCGGCATCGACCCCGCGAAGCACGA
CATCCGCTTCGTTGAGGATGACTGGGAGTCGCCGACCCTTGGTGCCTGGGGCTTGGGCTGGGAGGTCTGGCTCGACGGCA
TGGAGATCACCCAGTTCACCTATTTCCAGCAGGCCGGCGGGATCGACCTGAAGCCGGTATCGTCGGAGATCACCTACGGC
TGCGAGCGGATCGCCATGTACCTGCAAGGGGTCGACAACGTCTACGACCTGGAGTGGGTCAAGGGGGTGAGCTACGGCGA
TATCCACCACCGGACCGAGGTGGAGTTTTCCACCTACAACTTCGAGGAAGCGGACGTGGACATGCTCCTCACCCTGTTCA
CCATGTACGAGAAGGAGTGCGTGCGCCTGGTGGAGCGCGGTCTCGTGCTCCCGGCCTACGATTTCGTCATGAAGTGCTCC
CACACCTTCAACCTCCTGGATGCCCGGGGGGCCATCTCGGTCACCGAGCGCGCCTCCTACATCGGCCGGGTCCGCAATGT
GGCCCGTCTCTGCGCCGAAGGCTACCTGAAGCTCCGCGAAAGCCTGGGCTTCCCGCTGCTGAAAGGAGGACGGAAGTAA

Upstream 100 bases:

>100_bases
GTGCTCTAATTGTGCGTAACTTGGACGCTTTTTCACTTTGGCCAAATCCTGTTTACGCACGATAAAGCTTTTTTCATTTT
ATGCCAGGGGAGGAACCACC

Downstream 100 bases:

>100_bases
CATGAGCAAGGAACTGTTTCTCGAAATAGGCACCGAGGAGATCCCCGCCGGCTTCCTGCCCAAGGCCATGGCCGACATGG
AGGCCATCGTCACGAAGGAG

Product: glycyl-tRNA synthetase subunit alpha

Products: NA

Alternate protein names: Glycine--tRNA ligase alpha subunit; GlyRS

Number of amino acids: Translated: 292; Mature: 291

Protein sequence:

>292_residues
MTFQDLILALQGYWAQQGCVIQQPYDTEKGAGTFNPATFLRVLGPEPWNVAYVEPSRRPTDGRYGENPNRLQHYYQFQVI
MKPSPMNILDLYLDSLRAFGIDPAKHDIRFVEDDWESPTLGAWGLGWEVWLDGMEITQFTYFQQAGGIDLKPVSSEITYG
CERIAMYLQGVDNVYDLEWVKGVSYGDIHHRTEVEFSTYNFEEADVDMLLTLFTMYEKECVRLVERGLVLPAYDFVMKCS
HTFNLLDARGAISVTERASYIGRVRNVARLCAEGYLKLRESLGFPLLKGGRK

Sequences:

>Translated_292_residues
MTFQDLILALQGYWAQQGCVIQQPYDTEKGAGTFNPATFLRVLGPEPWNVAYVEPSRRPTDGRYGENPNRLQHYYQFQVI
MKPSPMNILDLYLDSLRAFGIDPAKHDIRFVEDDWESPTLGAWGLGWEVWLDGMEITQFTYFQQAGGIDLKPVSSEITYG
CERIAMYLQGVDNVYDLEWVKGVSYGDIHHRTEVEFSTYNFEEADVDMLLTLFTMYEKECVRLVERGLVLPAYDFVMKCS
HTFNLLDARGAISVTERASYIGRVRNVARLCAEGYLKLRESLGFPLLKGGRK
>Mature_291_residues
TFQDLILALQGYWAQQGCVIQQPYDTEKGAGTFNPATFLRVLGPEPWNVAYVEPSRRPTDGRYGENPNRLQHYYQFQVIM
KPSPMNILDLYLDSLRAFGIDPAKHDIRFVEDDWESPTLGAWGLGWEVWLDGMEITQFTYFQQAGGIDLKPVSSEITYGC
ERIAMYLQGVDNVYDLEWVKGVSYGDIHHRTEVEFSTYNFEEADVDMLLTLFTMYEKECVRLVERGLVLPAYDFVMKCSH
TFNLLDARGAISVTERASYIGRVRNVARLCAEGYLKLRESLGFPLLKGGRK

Specific function: Unknown

COG id: COG0752

COG function: function code J; Glycyl-tRNA synthetase, alpha subunit

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-II aminoacyl-tRNA synthetase family

Homologues:

Organism=Escherichia coli, GI1789983, Length=291, Percent_Identity=66.6666666666667, Blast_Score=402, Evalue=1e-113,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): SYGA_GEOSL (Q74FM8)

Other databases:

- EMBL:   AE017180
- RefSeq:   NP_951636.1
- HSSP:   Q9WY59
- ProteinModelPortal:   Q74FM8
- SMR:   Q74FM8
- GeneID:   2685617
- GenomeReviews:   AE017180_GR
- KEGG:   gsu:GSU0578
- NMPDR:   fig|243231.1.peg.574
- TIGR:   GSU0578
- HOGENOM:   HBG285316
- OMA:   CRRPTDG
- ProtClustDB:   PRK09348
- BioCyc:   GSUL243231:GSU_0578-MONOMER
- BRENDA:   6.1.1.14
- GO:   GO:0005737
- HAMAP:   MF_00254
- InterPro:   IPR006194
- InterPro:   IPR002310
- PRINTS:   PR01044
- TIGRFAMs:   TIGR00388

Pfam domain/function: PF02091 tRNA-synt_2e

EC number: =6.1.1.14

Molecular weight: Translated: 33479; Mature: 33348

Theoretical pI: Translated: 4.75; Mature: 4.75

Prosite motif: PS50861 AA_TRNA_LIGASE_II_GLYAB

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
4.5 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTFQDLILALQGYWAQQGCVIQQPYDTEKGAGTFNPATFLRVLGPEPWNVAYVEPSRRPT
CCHHHHHHHHHCCCCCCCEEEECCCCCCCCCCCCCHHHHHHEECCCCCEEEEECCCCCCC
DGRYGENPNRLQHYYQFQVIMKPSPMNILDLYLDSLRAFGIDPAKHDIRFVEDDWESPTL
CCCCCCCHHHHHHEEEEEEEECCCCCHHHHHHHHHHHHCCCCCCCCCCEEEECCCCCCCC
GAWGLGWEVWLDGMEITQFTYFQQAGGIDLKPVSSEITYGCERIAMYLQGVDNVYDLEWV
CCCCCCHHHEECCCHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCCCHHHH
KGVSYGDIHHRTEVEFSTYNFEEADVDMLLTLFTMYEKECVRLVERGLVLPAYDFVMKCS
CCCCCCCCCCCEEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHH
HTFNLLDARGAISVTERASYIGRVRNVARLCAEGYLKLRESLGFPLLKGGRK
HHHHEECCCCCEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCC
>Mature Secondary Structure 
TFQDLILALQGYWAQQGCVIQQPYDTEKGAGTFNPATFLRVLGPEPWNVAYVEPSRRPT
CHHHHHHHHHCCCCCCCEEEECCCCCCCCCCCCCHHHHHHEECCCCCEEEEECCCCCCC
DGRYGENPNRLQHYYQFQVIMKPSPMNILDLYLDSLRAFGIDPAKHDIRFVEDDWESPTL
CCCCCCCHHHHHHEEEEEEEECCCCCHHHHHHHHHHHHCCCCCCCCCCEEEECCCCCCCC
GAWGLGWEVWLDGMEITQFTYFQQAGGIDLKPVSSEITYGCERIAMYLQGVDNVYDLEWV
CCCCCCHHHEECCCHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCCCHHHH
KGVSYGDIHHRTEVEFSTYNFEEADVDMLLTLFTMYEKECVRLVERGLVLPAYDFVMKCS
CCCCCCCCCCCEEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHH
HTFNLLDARGAISVTERASYIGRVRNVARLCAEGYLKLRESLGFPLLKGGRK
HHHHEECCCCCEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA