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The map label for this gene is tag [H]

Identifier: 39995674

GI number: 39995674

Start: 597360

End: 597935

Strand: Direct

Name: tag [H]

Synonym: GSU0567

Alternate gene names: 39995674

Gene position: 597360-597935 (Clockwise)

Preceding gene: 308513282

Following gene: 39995675

Centisome position: 15.66

GC content: 65.97

Gene sequence:

>576_bases
ATGATCCAACGATGCGAATGGTGCGGCACCGATCCCCTCTACGTGGCCTACCACGACGGGGAATGGGGCGTGCCCGCCCA
CGATGACCGGCACCTCTTCGAGATGCTGATCCTGGAGGGGGCCCAGGCGGGGCTTTCATGGCTGACGATCCTGCGCAAGC
GCGAGGCGTACCGCCGGGCATTCGCCGGGTTCGACGCGGAAACGGTGGCCGCCTGGTCCGAGGCCGACGTGGCGCGGCTG
CTGGCCGATCCGGGGATCGTGCGCAACCGGCTCAAGATCGAGTCGACCATCAGGAATGCCCGGGGCGTGCTGAAGATCCG
GGAGGAGTTCGGCTCTCTCGATGCCTACCTGTGGCGGTTCGTGGACCATGCGCCCCGGCACAATGCCTGGCGCAGCCTGA
CCGATATCCCGGCCCGGACGGAGCAGTCCGATGCCATGAGCAAGGACCTGAAGCGGCGGGGCTTCAATTTCGTGGGGTCG
ACCATTTGCTACGCGTTCATGCAGGCGGTGGGGATGGTGAACGACCATGTGGTCCACTGCTTTCGGCACGACGAGATCAG
GCGGAGCGGGGGATGA

Upstream 100 bases:

>100_bases
CAAGATTTCCGGGTTTTCGCCCGAGACGATCGATTATTATCTGGAGAACGGCCGGTAAGGCCATTGCCCGCAGCCGTCTC
CGTTACGACAGGAGCATGAC

Downstream 100 bases:

>100_bases
CGTCTTCCATCCTCAAGGCATGCGCCATCTGGCTCCTGTTCATCCCGCTGGGAATCGTGAACGGCGTTGTGCGTGAAAAG
GTCCTGAACCCGCTGGTGGG

Product: DNA-3-methyladenine glycosylase

Products: NA

Alternate protein names: 3-methyladenine-DNA glycosylase I, constitutive; TAG I; DNA-3-methyladenine glycosidase I; DNA-3-methyladenine glycosylase I [H]

Number of amino acids: Translated: 191; Mature: 191

Protein sequence:

>191_residues
MIQRCEWCGTDPLYVAYHDGEWGVPAHDDRHLFEMLILEGAQAGLSWLTILRKREAYRRAFAGFDAETVAAWSEADVARL
LADPGIVRNRLKIESTIRNARGVLKIREEFGSLDAYLWRFVDHAPRHNAWRSLTDIPARTEQSDAMSKDLKRRGFNFVGS
TICYAFMQAVGMVNDHVVHCFRHDEIRRSGG

Sequences:

>Translated_191_residues
MIQRCEWCGTDPLYVAYHDGEWGVPAHDDRHLFEMLILEGAQAGLSWLTILRKREAYRRAFAGFDAETVAAWSEADVARL
LADPGIVRNRLKIESTIRNARGVLKIREEFGSLDAYLWRFVDHAPRHNAWRSLTDIPARTEQSDAMSKDLKRRGFNFVGS
TICYAFMQAVGMVNDHVVHCFRHDEIRRSGG
>Mature_191_residues
MIQRCEWCGTDPLYVAYHDGEWGVPAHDDRHLFEMLILEGAQAGLSWLTILRKREAYRRAFAGFDAETVAAWSEADVARL
LADPGIVRNRLKIESTIRNARGVLKIREEFGSLDAYLWRFVDHAPRHNAWRSLTDIPARTEQSDAMSKDLKRRGFNFVGS
TICYAFMQAVGMVNDHVVHCFRHDEIRRSGG

Specific function: Hydrolysis of the deoxyribose N-glycosidic bond to excise 3-methyladenine from the damaged DNA polymer formed by alkylation lesions [H]

COG id: COG2818

COG function: function code L; 3-methyladenine DNA glycosylase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Escherichia coli, GI1789971, Length=179, Percent_Identity=54.7486033519553, Blast_Score=216, Evalue=8e-58,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005019
- InterPro:   IPR011257
- InterPro:   IPR004597 [H]

Pfam domain/function: PF03352 Adenine_glyco [H]

EC number: =3.2.2.20 [H]

Molecular weight: Translated: 21893; Mature: 21893

Theoretical pI: Translated: 7.62; Mature: 7.62

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.1 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
4.7 %Cys+Met (Translated Protein)
2.1 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
4.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIQRCEWCGTDPLYVAYHDGEWGVPAHDDRHLFEMLILEGAQAGLSWLTILRKREAYRRA
CCCCCCCCCCCCEEEEEECCCCCCCCCCHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHH
FAGFDAETVAAWSEADVARLLADPGIVRNRLKIESTIRNARGVLKIREEFGSLDAYLWRF
HHCCCHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHH
VDHAPRHNAWRSLTDIPARTEQSDAMSKDLKRRGFNFVGSTICYAFMQAVGMVNDHVVHC
HHCCCCCHHHHHHHCCCCCCCHHHHHHHHHHHHCCHHHHHHHHHHHHHHHCCHHHHHHHH
FRHDEIRRSGG
HHHHHHHHCCC
>Mature Secondary Structure
MIQRCEWCGTDPLYVAYHDGEWGVPAHDDRHLFEMLILEGAQAGLSWLTILRKREAYRRA
CCCCCCCCCCCCEEEEEECCCCCCCCCCHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHH
FAGFDAETVAAWSEADVARLLADPGIVRNRLKIESTIRNARGVLKIREEFGSLDAYLWRF
HHCCCHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHH
VDHAPRHNAWRSLTDIPARTEQSDAMSKDLKRRGFNFVGSTICYAFMQAVGMVNDHVVHC
HHCCCCCHHHHHHHCCCCCCCHHHHHHHHHHHHCCHHHHHHHHHHHHHHHCCHHHHHHHH
FRHDEIRRSGG
HHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 3536912; 3520491; 8041620; 9278503 [H]