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The map label for this gene is trxB [H]

Identifier: 39995596

GI number: 39995596

Start: 518779

End: 519729

Strand: Direct

Name: trxB [H]

Synonym: GSU0488

Alternate gene names: 39995596

Gene position: 518779-519729 (Clockwise)

Preceding gene: 39995593

Following gene: 39995597

Centisome position: 13.6

GC content: 62.78

Gene sequence:

>951_bases
ATGCAAGCAACCCACCATCGTCTCCTTATTCTCGGTTCCGGCCCCGCCGGCTACACCGCTGCCGTCTACGCGGCTCGCGC
CAACCTGAGCCCAGCCCTCATCACCGGACTCCAGCAGGGCGGCCAACTCATGACCACCACCGAGGTGGACAACTGGCCCG
GCGACCCCGACGGCGTGCTCGGTCCCGACCTCATGGACCGGATGCGGCGCCACGCCGAGCGCTTCAACACCGCCATGATC
TATGATCATATCCATACCGCCAATCTTCGGGAGCGCCCGTTCCGGCTCGAGGGGGATTCCGGTATCTACACCTGCGACGC
ACTCATCATCGCCACCGGTGCATCGGCACGCTATCTCGGGCTTCCTTCAGAAGAAGCGTTCAAGGGCAAAGGCGTATCCG
CCTGCGCCACCTGCGATGGCTTCTTCTACCGCGGGAAACCGGTGGCGGTAATCGGCGGCGGTAACACGGCCGTTGAGGAG
GCCCTCTATCTATCCAACATTGCCAGCCACGTCACGCTCGTCCACCGGCGCGACAAGCTGAGAGCCGAGAAAATCCTGGC
TGACAAGCTGATCGAAAAGACGCGCGGCGGCAACGTCACCATCGAGTGGAACCACGTCCTGGATGAGGTCCTCGGCGATC
AGGCCGGGGTGACCGGCGTCCGCATCCGCCATACGAGCGGATCCACCAAGGAGCTCGATGTCCACGGCTGTTTCATTGCC
ATCGGGCATACTCCCAACACTCACCTGTTCGAGGGACAGCTGGAGATGGACGAGGGGTATATACGGACCCAGTGCGGTGC
CGAAGGGAACTTCACCGCCACGAGTATTCCCGGTGTCTTCGCCGCCGGCGATGTTCAGGACCAGCATTACCGCCAAGCGA
TCACCTCTGCCGGCACCGGTTGCATGGCTGCCCTCGACGCCGAGCGCTATCTGGATATGCTCAAACCCTGA

Upstream 100 bases:

>100_bases
AAGCGCCGACTGGCCGGTCAATGGTAAAGAGCCCGTCTACGCTTGCAATTCCCCAAGGTTGCTGGTATCTTGTCGCGATA
GTTTTTTGGAGGGCTTTAAT

Downstream 100 bases:

>100_bases
CCGCCATGCTCGCCAAAGCCCTCTCCAGCGCCCTTCTCGGAATCGATGCCGTCATCGTCGACGTGGAGGTGGATATTTCG
CCGGGGCTTCCCCAGTTCGC

Product: thioredoxin reductase

Products: NA

Alternate protein names: TRXR [H]

Number of amino acids: Translated: 316; Mature: 316

Protein sequence:

>316_residues
MQATHHRLLILGSGPAGYTAAVYAARANLSPALITGLQQGGQLMTTTEVDNWPGDPDGVLGPDLMDRMRRHAERFNTAMI
YDHIHTANLRERPFRLEGDSGIYTCDALIIATGASARYLGLPSEEAFKGKGVSACATCDGFFYRGKPVAVIGGGNTAVEE
ALYLSNIASHVTLVHRRDKLRAEKILADKLIEKTRGGNVTIEWNHVLDEVLGDQAGVTGVRIRHTSGSTKELDVHGCFIA
IGHTPNTHLFEGQLEMDEGYIRTQCGAEGNFTATSIPGVFAAGDVQDQHYRQAITSAGTGCMAALDAERYLDMLKP

Sequences:

>Translated_316_residues
MQATHHRLLILGSGPAGYTAAVYAARANLSPALITGLQQGGQLMTTTEVDNWPGDPDGVLGPDLMDRMRRHAERFNTAMI
YDHIHTANLRERPFRLEGDSGIYTCDALIIATGASARYLGLPSEEAFKGKGVSACATCDGFFYRGKPVAVIGGGNTAVEE
ALYLSNIASHVTLVHRRDKLRAEKILADKLIEKTRGGNVTIEWNHVLDEVLGDQAGVTGVRIRHTSGSTKELDVHGCFIA
IGHTPNTHLFEGQLEMDEGYIRTQCGAEGNFTATSIPGVFAAGDVQDQHYRQAITSAGTGCMAALDAERYLDMLKP
>Mature_316_residues
MQATHHRLLILGSGPAGYTAAVYAARANLSPALITGLQQGGQLMTTTEVDNWPGDPDGVLGPDLMDRMRRHAERFNTAMI
YDHIHTANLRERPFRLEGDSGIYTCDALIIATGASARYLGLPSEEAFKGKGVSACATCDGFFYRGKPVAVIGGGNTAVEE
ALYLSNIASHVTLVHRRDKLRAEKILADKLIEKTRGGNVTIEWNHVLDEVLGDQAGVTGVRIRHTSGSTKELDVHGCFIA
IGHTPNTHLFEGQLEMDEGYIRTQCGAEGNFTATSIPGVFAAGDVQDQHYRQAITSAGTGCMAALDAERYLDMLKP

Specific function: Unknown

COG id: COG0492

COG function: function code O; Thioredoxin reductase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family [H]

Homologues:

Organism=Escherichia coli, GI1787114, Length=312, Percent_Identity=71.7948717948718, Blast_Score=464, Evalue=1e-132,
Organism=Escherichia coli, GI87081763, Length=315, Percent_Identity=35.8730158730159, Blast_Score=154, Evalue=6e-39,
Organism=Saccharomyces cerevisiae, GI6320560, Length=324, Percent_Identity=48.1481481481481, Blast_Score=286, Evalue=2e-78,
Organism=Saccharomyces cerevisiae, GI6321898, Length=320, Percent_Identity=46.5625, Blast_Score=280, Evalue=2e-76,

Paralogues:

None

Copy number: 808 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. 2,000 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013027
- InterPro:   IPR008255
- InterPro:   IPR001327
- InterPro:   IPR000103
- InterPro:   IPR005982 [H]

Pfam domain/function: PF00070 Pyr_redox; PF07992 Pyr_redox_2 [H]

EC number: =1.8.1.9 [H]

Molecular weight: Translated: 34082; Mature: 34082

Theoretical pI: Translated: 6.32; Mature: 6.32

Prosite motif: PS00573 PYRIDINE_REDOX_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.9 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
4.4 %Cys+Met (Translated Protein)
1.9 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
4.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQATHHRLLILGSGPAGYTAAVYAARANLSPALITGLQQGGQLMTTTEVDNWPGDPDGVL
CCCCCEEEEEEECCCCCCEEEEEEECCCCCHHHHHHHHCCCEEEEEEECCCCCCCCCCCC
GPDLMDRMRRHAERFNTAMIYDHIHTANLRERPFRLEGDSGIYTCDALIIATGASARYLG
CHHHHHHHHHHHHHHCEEEEEECCCCCCCCCCCEEEECCCCEEEEEEEEEECCCCCEEEC
LPSEEAFKGKGVSACATCDGFFYRGKPVAVIGGGNTAVEEALYLSNIASHVTLVHRRDKL
CCCHHHHCCCCCEEEEECCCEEECCCEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHH
RAEKILADKLIEKTRGGNVTIEWNHVLDEVLGDQAGVTGVRIRHTSGSTKELDVHGCFIA
HHHHHHHHHHHHHHCCCEEEEEHHHHHHHHHCCCCCCCEEEEEECCCCCEEEEEEEEEEE
IGHTPNTHLFEGQLEMDEGYIRTQCGAEGNFTATSIPGVFAAGDVQDQHYRQAITSAGTG
ECCCCCCEEEECEEECCCCEEEEECCCCCCEEEECCCCEEEECCCCHHHHHHHHHHCCCC
CMAALDAERYLDMLKP
CEEHHCHHHHHHHHCC
>Mature Secondary Structure
MQATHHRLLILGSGPAGYTAAVYAARANLSPALITGLQQGGQLMTTTEVDNWPGDPDGVL
CCCCCEEEEEEECCCCCCEEEEEEECCCCCHHHHHHHHCCCEEEEEEECCCCCCCCCCCC
GPDLMDRMRRHAERFNTAMIYDHIHTANLRERPFRLEGDSGIYTCDALIIATGASARYLG
CHHHHHHHHHHHHHHCEEEEEECCCCCCCCCCCEEEECCCCEEEEEEEEEECCCCCEEEC
LPSEEAFKGKGVSACATCDGFFYRGKPVAVIGGGNTAVEEALYLSNIASHVTLVHRRDKL
CCCHHHHCCCCCEEEEECCCEEECCCEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHH
RAEKILADKLIEKTRGGNVTIEWNHVLDEVLGDQAGVTGVRIRHTSGSTKELDVHGCFIA
HHHHHHHHHHHHHHCCCEEEEEHHHHHHHHHCCCCCCCEEEEEECCCCCEEEEEEEEEEE
IGHTPNTHLFEGQLEMDEGYIRTQCGAEGNFTATSIPGVFAAGDVQDQHYRQAITSAGTG
ECCCCCCEEEECEEECCCCEEEEECCCCCCEEEECCCCEEEECCCCHHHHHHHHHHCCCC
CMAALDAERYLDMLKP
CEEHHCHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10952301 [H]