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The map label for this gene is efp-1

Identifier: 39995573

GI number: 39995573

Start: 495363

End: 495926

Strand: Direct

Name: efp-1

Synonym: GSU0465

Alternate gene names: 39995573

Gene position: 495363-495926 (Clockwise)

Preceding gene: 39995563

Following gene: 39995580

Centisome position: 12.99

GC content: 62.59

Gene sequence:

>564_bases
ATGCTTACCACATCCGATTTCAAACGCGGCCTTGTCATCAAGCTCGACAACTCCCCGTGCCTCATCCTCGACGTCCACTT
CCAGTCCCCGTCCGCCCGGGGGGCCAGCACCATGGTCAAGACCCGCTACCGCAACCTCCTGACCGGCCAGGTGCTCGACA
AGACCTTCCGCTCCGGCGACAAGGTGGAAGAGGCCGACTTCGAGCGCCACAAGGGGCAATACCTCTACGCCGACGGCGAC
CGCGGCGTCTTCATGGATATGGAGACCTATGAACAGTTCGAGATGGACGCCGAGTCCTTCCAGGTCATCCAGCCCTACCT
CCTCGACGGAACCGAGGTGGTCCTCGGTCTCTTCCAAGAGCGGCTCGTCAGCGTCGATCCGCCCCAGGTGGTGGAGCTGA
CCATCACCGATACCCCGCCGGTCATCAAGAATGCCACCGCCACTGCCCAGACCAAGGAGGCCACCCTCGAAACCGGCCTC
ACCCTCCAGGTCCCTCCCTATCTGGAGGTTGGCGAGAAGATCAAAGTCGACACCCGCGACTGCCGGTTCATATCCCGCGC
CTGA

Upstream 100 bases:

>100_bases
CATGGGCTCTCCGCGGGGCATCATGCCCCGTTCATACGGTTGTCTTTGTAGCATTTTTCTGGTAAGAATAGCGAGATTTT
TTACCCATGGAGAACGACAC

Downstream 100 bases:

>100_bases
GCGGGGATCAGGGGGCTGAGTATCCTCGTGCCGGCTCCGGATTACTCGAAAAAAGGGTTGACACAAACCCTGCTTCGGTT
TATAACCTAAAGCTCTTTTC

Product: elongation factor P

Products: NA

Alternate protein names: EF-P 1

Number of amino acids: Translated: 187; Mature: 187

Protein sequence:

>187_residues
MLTTSDFKRGLVIKLDNSPCLILDVHFQSPSARGASTMVKTRYRNLLTGQVLDKTFRSGDKVEEADFERHKGQYLYADGD
RGVFMDMETYEQFEMDAESFQVIQPYLLDGTEVVLGLFQERLVSVDPPQVVELTITDTPPVIKNATATAQTKEATLETGL
TLQVPPYLEVGEKIKVDTRDCRFISRA

Sequences:

>Translated_187_residues
MLTTSDFKRGLVIKLDNSPCLILDVHFQSPSARGASTMVKTRYRNLLTGQVLDKTFRSGDKVEEADFERHKGQYLYADGD
RGVFMDMETYEQFEMDAESFQVIQPYLLDGTEVVLGLFQERLVSVDPPQVVELTITDTPPVIKNATATAQTKEATLETGL
TLQVPPYLEVGEKIKVDTRDCRFISRA
>Mature_187_residues
MLTTSDFKRGLVIKLDNSPCLILDVHFQSPSARGASTMVKTRYRNLLTGQVLDKTFRSGDKVEEADFERHKGQYLYADGD
RGVFMDMETYEQFEMDAESFQVIQPYLLDGTEVVLGLFQERLVSVDPPQVVELTITDTPPVIKNATATAQTKEATLETGL
TLQVPPYLEVGEKIKVDTRDCRFISRA

Specific function: Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing t

COG id: COG0231

COG function: function code J; Translation elongation factor P (EF-P)/translation initiation factor 5A (eIF-5A)

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the elongation factor P family

Homologues:

Organism=Escherichia coli, GI1790590, Length=183, Percent_Identity=39.8907103825137, Blast_Score=132, Evalue=1e-32,
Organism=Escherichia coli, GI87082061, Length=189, Percent_Identity=33.8624338624339, Blast_Score=120, Evalue=8e-29,

Paralogues:

None

Copy number: 1600 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): EFP1_GEOSL (Q74FY7)

Other databases:

- EMBL:   AE017180
- RefSeq:   NP_951524.1
- ProteinModelPortal:   Q74FY7
- GeneID:   2686244
- GenomeReviews:   AE017180_GR
- KEGG:   gsu:GSU0465
- NMPDR:   fig|243231.1.peg.462
- TIGR:   GSU0465
- HOGENOM:   HBG303311
- OMA:   YEQFEMD
- ProtClustDB:   PRK14578
- BioCyc:   GSUL243231:GSU_0465-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_00141
- InterPro:   IPR015365
- InterPro:   IPR012340
- InterPro:   IPR016027
- InterPro:   IPR020599
- InterPro:   IPR013185
- InterPro:   IPR001059
- InterPro:   IPR013852
- InterPro:   IPR011768
- InterPro:   IPR014722
- InterPro:   IPR008991
- Gene3D:   G3DSA:2.40.50.140
- Gene3D:   G3DSA:2.30.30.30
- PIRSF:   PIRSF005901
- SMART:   SM00841
- TIGRFAMs:   TIGR00038

Pfam domain/function: PF01132 EFP; PF08207 EFP_N; PF09285 Elong-fact-P_C; SSF50249 Nucleic_acid_OB; SSF50104 Transl_SH3_like

EC number: NA

Molecular weight: Translated: 21059; Mature: 21059

Theoretical pI: Translated: 4.59; Mature: 4.59

Prosite motif: PS01275 EFP

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLTTSDFKRGLVIKLDNSPCLILDVHFQSPSARGASTMVKTRYRNLLTGQVLDKTFRSGD
CCCCCCCCCCEEEEECCCCEEEEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCC
KVEEADFERHKGQYLYADGDRGVFMDMETYEQFEMDAESFQVIQPYLLDGTEVVLGLFQE
CCCHHHHHHHCCCEEEEECCCCEEEEHHHHHHHHCCHHHHHHHHHHHCCHHHHHHHHHHH
RLVSVDPPQVVELTITDTPPVIKNATATAQTKEATLETGLTLQVPPYLEVGEKIKVDTRD
HHCCCCCCCEEEEEECCCCCCCCCCCCCCCCHHHHHHCCCEEECCCCCCCCCEEEECCHH
CRFISRA
CEEECCC
>Mature Secondary Structure
MLTTSDFKRGLVIKLDNSPCLILDVHFQSPSARGASTMVKTRYRNLLTGQVLDKTFRSGD
CCCCCCCCCCEEEEECCCCEEEEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCC
KVEEADFERHKGQYLYADGDRGVFMDMETYEQFEMDAESFQVIQPYLLDGTEVVLGLFQE
CCCHHHHHHHCCCEEEEECCCCEEEEHHHHHHHHCCHHHHHHHHHHHCCHHHHHHHHHHH
RLVSVDPPQVVELTITDTPPVIKNATATAQTKEATLETGLTLQVPPYLEVGEKIKVDTRD
HHCCCCCCCEEEEEECCCCCCCCCCCCCCCCHHHHHHCCCEEECCCCCCCCCEEEECCHH
CRFISRA
CEEECCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA