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The map label for this gene is hypA

Identifier: 39995482

GI number: 39995482

Start: 409015

End: 409347

Strand: Direct

Name: hypA

Synonym: GSU0374

Alternate gene names: 39995482

Gene position: 409015-409347 (Clockwise)

Preceding gene: 39995475

Following gene: 39995483

Centisome position: 10.72

GC content: 65.77

Gene sequence:

>333_bases
GTGCATGAAATGTCCATAACCCAAAACGTGGTAGAAATATGCGAGAAAAGCGCGGAGGGCCGGCGAATTCTGGCGGTCGT
GCTGGAGATCGGCGAGCTGTCCGGCGTGGTGCCCGAGGCCGTGGAGTTCTGCTTCGAGGCATGCACCGCCGGCACCCTTG
CCGAGGGGGCACGGCTTGCCATCGACCGTGTTCCCGGCCGGGGAGAGTGCGGCAACTGCGCCACCGTGTTCCCGGTCCGG
ACCTACTTCGACCCCTGTCCCGCCTGCGGCGCCTACGGGGTGCGGGTGGTGGCCGGTGAAGAGCTGCGGGTAAAGGAACT
GGAGGTCGAGTAG

Upstream 100 bases:

>100_bases
AAGGCGGCTCTCCCAGCGCTTCTTTTGTAGGATAAACTCTGCTATGATCGGCCGGAACGACCAGACCGCCCGGCAGATGG
GGGTGAGGAGGATGGAAGCT

Downstream 100 bases:

>100_bases
ACGATCCGTCTGCCCGGCGCAGTGGCAACGTCGGTTTCCTGCGGTAAAATCGTTTACAAACCCCCGGTCATCATTTACAG
TTGTGGCCCCGCCCACAGCC

Product: hydrogenase expression/formation protein HupA

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 110; Mature: 110

Protein sequence:

>110_residues
MHEMSITQNVVEICEKSAEGRRILAVVLEIGELSGVVPEAVEFCFEACTAGTLAEGARLAIDRVPGRGECGNCATVFPVR
TYFDPCPACGAYGVRVVAGEELRVKELEVE

Sequences:

>Translated_110_residues
MHEMSITQNVVEICEKSAEGRRILAVVLEIGELSGVVPEAVEFCFEACTAGTLAEGARLAIDRVPGRGECGNCATVFPVR
TYFDPCPACGAYGVRVVAGEELRVKELEVE
>Mature_110_residues
MHEMSITQNVVEICEKSAEGRRILAVVLEIGELSGVVPEAVEFCFEACTAGTLAEGARLAIDRVPGRGECGNCATVFPVR
TYFDPCPACGAYGVRVVAGEELRVKELEVE

Specific function: Probably plays a role in an hydrogenase nickel cofactor insertion step

COG id: COG0375

COG function: function code R; Zn finger protein HypA/HybF (possibly regulating hydrogenase expression)

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the hypA/hybF family

Homologues:

Organism=Escherichia coli, GI1789365, Length=113, Percent_Identity=41.5929203539823, Blast_Score=83, Evalue=5e-18,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): HYPA_GEOSL (Q74G73)

Other databases:

- EMBL:   AE017180
- RefSeq:   NP_951433.1
- GeneID:   2686247
- GenomeReviews:   AE017180_GR
- KEGG:   gsu:GSU0374
- NMPDR:   fig|243231.1.peg.371
- TIGR:   GSU0374
- HOGENOM:   HBG688671
- OMA:   MHEMSLC
- ProtClustDB:   CLSK827786
- BioCyc:   GSUL243231:GSU_0374-MONOMER
- HAMAP:   MF_00213
- InterPro:   IPR000688
- InterPro:   IPR020538
- TIGRFAMs:   TIGR00100

Pfam domain/function: PF01155 HypA

EC number: NA

Molecular weight: Translated: 11791; Mature: 11791

Theoretical pI: Translated: 4.29; Mature: 4.29

Prosite motif: PS01249 HYPA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

6.4 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
8.2 %Cys+Met (Translated Protein)
6.4 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
8.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MHEMSITQNVVEICEKSAEGRRILAVVLEIGELSGVVPEAVEFCFEACTAGTLAEGARLA
CCCCHHHHHHHHHHHCCCCCCCHHHHHHHHHHHCCCCHHHHHHHHHHHCCCCCCCCCEEE
IDRVPGRGECGNCATVFPVRTYFDPCPACGAYGVRVVAGEELRVKELEVE
EECCCCCCCCCCCEEEEEHHHHCCCCCCCCCCCEEEEECCCEEEEEECCC
>Mature Secondary Structure
MHEMSITQNVVEICEKSAEGRRILAVVLEIGELSGVVPEAVEFCFEACTAGTLAEGARLA
CCCCHHHHHHHHHHHCCCCCCCHHHHHHHHHHHCCCCHHHHHHHHHHHCCCCCCCCCEEE
IDRVPGRGECGNCATVFPVRTYFDPCPACGAYGVRVVAGEELRVKELEVE
EECCCCCCCCCCCEEEEEHHHHCCCCCCCCCCCEEEEECCCEEEEEECCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA