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The map label for this gene is dnaX [H]

Identifier: 39995205

GI number: 39995205

Start: 106783

End: 108522

Strand: Direct

Name: dnaX [H]

Synonym: GSU0094

Alternate gene names: 39995205

Gene position: 106783-108522 (Clockwise)

Preceding gene: 39995204

Following gene: 39995206

Centisome position: 2.8

GC content: 63.51

Gene sequence:

>1740_bases
GTGTCCTATCTCGTTCTCGCACGAAAGTGGCGTCCCCAGACCTTCAGCGACCTCACGGGACAGGAGCACGTCAGCCGAAC
CCTTCAGAACGCCATTGATTCCGGCAGGATCGCCCACGCGTTCCTCTTCACAGGGGCCCGCGGCGTCGGCAAAACCTCGT
CGGCCCGGATTCTGGCCAAGGCCCTCAACTGCGAGCAGGGTATGAGTCCCGAGCCGTGCAACGTCTGTCCCGCCTGTACC
GAGATCACGGCCGGCACCTCGGTCGATGTTCTTGAAATTGACGGGGCCTCCAACACCGGTGTCGACGATATTCGCGAACT
GCGGGAGAACGTCAAGTACCTTCCGTCGCGGTTGCGCTACAAGATCTTCATCATTGATGAAGTCCACATGCTCTCCACCA
ACGCCTTCAACGCCCTGTTGAAGACCCTGGAGGAGCCACCGCCCCACGTGAAGTTCATCTTTGCCACCACCGAGCCCCAC
AAGCTTCCCATCACCATACTCTCACGCTGCCAACGCTTCGATTTCCGGCGGATTCCGCTTGCAAAGGTGGTGGCCCGACT
GCGTTACATCGTCGACCGTGAGGGGATTTCCATCAGCGACGAGTCCCTTGCCGTGGTGGCGCGCAAGGGAGACGGCAGCA
TGCGGGACTCCCTGTCGGTCCTGGACCAGGTGCTTGCCTTCTGTGGCGAGACGGTGAACGATGATGATGTGGTGAGCCTT
CTGGGTGTCGTGGACCGGCGCCTGCTGCTGGAGGCGTCGGCCGCCGTTTTGGGCCGTGATACGCGCAGTGTGCTCGGGGT
GGTTGCCCGGGTGGACGAATTCGGTTACAACATGCGTCAGTTTTGCGGCGAACTTATCGACCATTTCCGCAATCTGACCA
TCATGAGGGCCGTGGGCGATGCGGGAGACCTGCTCGACCTCTCCGAGGCGGAGCTCCAGTCGGTTCGTGAACAGGCATCC
TCGGCGCTGCTGGAGGATCTGCAGCGGCACATGACAATCCTCCTGCGGGCCGACGGCGAGTTGGCTCACTCGGGCTACCC
CCGGCTGGTCCTGGAGATGGCGCTGGTTCGAATGGCGACGCTGGCGCCCCTGGTGCCGGTGGGTGAACTGCTGGACAGGC
TCGGCAGAATCGAGGAGCGGGGCAGCGGTGTTGCGGCCGACGCCCGGGCGTCATGGCGCCCCTCACCCCCGCCGGAGGCC
GGGGTCGCCCCTGTGCCGCGTCCGGCACCCTCTGCCCTGGCCGAACAACGACCCCGCCCCGTTCCTGCCGGGGCTGAGGC
AAAGCCGCCCCCGTCGCGTAGTGACTCGCCCGTTCAGGAACCTCGGCGGACCGGGGATGAGTGGGCCGATTTTGTTGCAT
TCGTCAAGGGGGCCAAGCCCCGGATCGGCACATCGCTGGAGTACGGCAGTCCGCTGCATATTGCCGCTGACCGCCTAGAA
ATCGGTTTTCCGGAAAACTCCTTTGCTCTGTCGAGCCTCCGGGACGGCGATGCGCAAGCATCTCTCAAGGCCTTGGCGGA
GCGCTTCTTCTCGGCACCCATGACGGTTGCCCTCAAGGTGTTGACCGGTGAAGGCCATGCGCCTCCCAACCTGCTTGAAA
AAAAAAGAGCTGAAGATGAGCAGCGCCGCACCGGCCTGAAGCGGTCGGCCGAATCCCATCCGGCGGTATCCTCGGCCCTT
GAGGTCTTTGACGGAACACTCGCAGAGGTTGCCCCGCTGGGGACGCGAGGCAAGCTATAA

Upstream 100 bases:

>100_bases
CCGCGGGGGAGCCCAGCTATCAGTTGTGCCCGCAAAATCCCCGATGTGCCCCTCTCCCTTCGCAAGCGCACGAACCGAAC
CCGTAGTGAGGTGTTGACCC

Downstream 100 bases:

>100_bases
CCATGTTTTAGTTTCAACAAAAGTCATTGAGCGAGAGTAAATTTACATCACAGTAACAATGGAGGAGAAGATGTCCAAGG
GTTTGGCCGGAATCATGAAA

Product: DNA polymerase III subunits gamma and tau

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 579; Mature: 578

Protein sequence:

>579_residues
MSYLVLARKWRPQTFSDLTGQEHVSRTLQNAIDSGRIAHAFLFTGARGVGKTSSARILAKALNCEQGMSPEPCNVCPACT
EITAGTSVDVLEIDGASNTGVDDIRELRENVKYLPSRLRYKIFIIDEVHMLSTNAFNALLKTLEEPPPHVKFIFATTEPH
KLPITILSRCQRFDFRRIPLAKVVARLRYIVDREGISISDESLAVVARKGDGSMRDSLSVLDQVLAFCGETVNDDDVVSL
LGVVDRRLLLEASAAVLGRDTRSVLGVVARVDEFGYNMRQFCGELIDHFRNLTIMRAVGDAGDLLDLSEAELQSVREQAS
SALLEDLQRHMTILLRADGELAHSGYPRLVLEMALVRMATLAPLVPVGELLDRLGRIEERGSGVAADARASWRPSPPPEA
GVAPVPRPAPSALAEQRPRPVPAGAEAKPPPSRSDSPVQEPRRTGDEWADFVAFVKGAKPRIGTSLEYGSPLHIAADRLE
IGFPENSFALSSLRDGDAQASLKALAERFFSAPMTVALKVLTGEGHAPPNLLEKKRAEDEQRRTGLKRSAESHPAVSSAL
EVFDGTLAEVAPLGTRGKL

Sequences:

>Translated_579_residues
MSYLVLARKWRPQTFSDLTGQEHVSRTLQNAIDSGRIAHAFLFTGARGVGKTSSARILAKALNCEQGMSPEPCNVCPACT
EITAGTSVDVLEIDGASNTGVDDIRELRENVKYLPSRLRYKIFIIDEVHMLSTNAFNALLKTLEEPPPHVKFIFATTEPH
KLPITILSRCQRFDFRRIPLAKVVARLRYIVDREGISISDESLAVVARKGDGSMRDSLSVLDQVLAFCGETVNDDDVVSL
LGVVDRRLLLEASAAVLGRDTRSVLGVVARVDEFGYNMRQFCGELIDHFRNLTIMRAVGDAGDLLDLSEAELQSVREQAS
SALLEDLQRHMTILLRADGELAHSGYPRLVLEMALVRMATLAPLVPVGELLDRLGRIEERGSGVAADARASWRPSPPPEA
GVAPVPRPAPSALAEQRPRPVPAGAEAKPPPSRSDSPVQEPRRTGDEWADFVAFVKGAKPRIGTSLEYGSPLHIAADRLE
IGFPENSFALSSLRDGDAQASLKALAERFFSAPMTVALKVLTGEGHAPPNLLEKKRAEDEQRRTGLKRSAESHPAVSSAL
EVFDGTLAEVAPLGTRGKL
>Mature_578_residues
SYLVLARKWRPQTFSDLTGQEHVSRTLQNAIDSGRIAHAFLFTGARGVGKTSSARILAKALNCEQGMSPEPCNVCPACTE
ITAGTSVDVLEIDGASNTGVDDIRELRENVKYLPSRLRYKIFIIDEVHMLSTNAFNALLKTLEEPPPHVKFIFATTEPHK
LPITILSRCQRFDFRRIPLAKVVARLRYIVDREGISISDESLAVVARKGDGSMRDSLSVLDQVLAFCGETVNDDDVVSLL
GVVDRRLLLEASAAVLGRDTRSVLGVVARVDEFGYNMRQFCGELIDHFRNLTIMRAVGDAGDLLDLSEAELQSVREQASS
ALLEDLQRHMTILLRADGELAHSGYPRLVLEMALVRMATLAPLVPVGELLDRLGRIEERGSGVAADARASWRPSPPPEAG
VAPVPRPAPSALAEQRPRPVPAGAEAKPPPSRSDSPVQEPRRTGDEWADFVAFVKGAKPRIGTSLEYGSPLHIAADRLEI
GFPENSFALSSLRDGDAQASLKALAERFFSAPMTVALKVLTGEGHAPPNLLEKKRAEDEQRRTGLKRSAESHPAVSSALE
VFDGTLAEVAPLGTRGKL

Specific function: DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria [H]

COG id: COG2812

COG function: function code L; DNA polymerase III, gamma/tau subunits

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Homo sapiens, GI194306571, Length=225, Percent_Identity=26.6666666666667, Blast_Score=83, Evalue=6e-16,
Organism=Homo sapiens, GI194306567, Length=225, Percent_Identity=26.6666666666667, Blast_Score=83, Evalue=6e-16,
Organism=Homo sapiens, GI6677723, Length=222, Percent_Identity=27.027027027027, Blast_Score=83, Evalue=7e-16,
Organism=Homo sapiens, GI31563534, Length=281, Percent_Identity=22.4199288256228, Blast_Score=75, Evalue=1e-13,
Organism=Homo sapiens, GI4506491, Length=291, Percent_Identity=24.7422680412371, Blast_Score=72, Evalue=1e-12,
Organism=Homo sapiens, GI31881687, Length=291, Percent_Identity=24.7422680412371, Blast_Score=72, Evalue=1e-12,
Organism=Escherichia coli, GI1786676, Length=373, Percent_Identity=42.8954423592493, Blast_Score=304, Evalue=9e-84,
Organism=Escherichia coli, GI1787341, Length=166, Percent_Identity=31.9277108433735, Blast_Score=70, Evalue=3e-13,
Organism=Caenorhabditis elegans, GI17554730, Length=275, Percent_Identity=24.3636363636364, Blast_Score=81, Evalue=2e-15,
Organism=Caenorhabditis elegans, GI71986063, Length=308, Percent_Identity=26.2987012987013, Blast_Score=81, Evalue=2e-15,
Organism=Caenorhabditis elegans, GI17541988, Length=285, Percent_Identity=23.859649122807, Blast_Score=71, Evalue=2e-12,
Organism=Saccharomyces cerevisiae, GI6324039, Length=238, Percent_Identity=27.3109243697479, Blast_Score=87, Evalue=6e-18,
Organism=Saccharomyces cerevisiae, GI6324478, Length=267, Percent_Identity=25.8426966292135, Blast_Score=84, Evalue=9e-17,
Organism=Saccharomyces cerevisiae, GI6322528, Length=299, Percent_Identity=24.0802675585284, Blast_Score=83, Evalue=1e-16,
Organism=Drosophila melanogaster, GI18859927, Length=248, Percent_Identity=25.8064516129032, Blast_Score=86, Evalue=7e-17,
Organism=Drosophila melanogaster, GI19921076, Length=239, Percent_Identity=28.4518828451883, Blast_Score=83, Evalue=6e-16,
Organism=Drosophila melanogaster, GI17647857, Length=311, Percent_Identity=24.4372990353698, Blast_Score=79, Evalue=9e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003593
- InterPro:   IPR003959
- InterPro:   IPR001270
- InterPro:   IPR008921
- InterPro:   IPR022754
- InterPro:   IPR012763 [H]

Pfam domain/function: PF00004 AAA; PF12169 DNA_pol3_gamma3 [H]

EC number: =2.7.7.7 [H]

Molecular weight: Translated: 63004; Mature: 62872

Theoretical pI: Translated: 6.45; Mature: 6.45

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSYLVLARKWRPQTFSDLTGQEHVSRTLQNAIDSGRIAHAFLFTGARGVGKTSSARILAK
CCEEEEECCCCCCCHHHCCCHHHHHHHHHHHHCCCCHHHHHHHHCCCCCCCCHHHHHHHH
ALNCEQGMSPEPCNVCPACTEITAGTSVDVLEIDGASNTGVDDIRELRENVKYLPSRLRY
HHHHCCCCCCCCCCCCCCHHHHCCCCCEEEEEECCCCCCCHHHHHHHHHHHHHHHHHCCE
KIFIIDEVHMLSTNAFNALLKTLEEPPPHVKFIFATTEPHKLPITILSRCQRFDFRRIPL
EEEEEECHHHHHHHHHHHHHHHHCCCCCCEEEEEEECCCCCCHHHHHHHHHHCCCCCCCH
AKVVARLRYIVDREGISISDESLAVVARKGDGSMRDSLSVLDQVLAFCGETVNDDDVVSL
HHHHHHHHHHHHCCCCCCCCCCEEEEEECCCCCHHHHHHHHHHHHHHHCCCCCCHHHHHH
LGVVDRRLLLEASAAVLGRDTRSVLGVVARVDEFGYNMRQFCGELIDHFRNLTIMRAVGD
HHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHCEEHEEECCC
AGDLLDLSEAELQSVREQASSALLEDLQRHMTILLRADGELAHSGYPRLVLEMALVRMAT
CCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHEEEEECCCCHHHCCCHHHHHHHHHHHHHH
LAPLVPVGELLDRLGRIEERGSGVAADARASWRPSPPPEAGVAPVPRPAPSALAEQRPRP
HHCCCCHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHCCCCC
VPAGAEAKPPPSRSDSPVQEPRRTGDEWADFVAFVKGAKPRIGTSLEYGSPLHIAADRLE
CCCCCCCCCCCCCCCCCHHHHHHCHHHHHHHHHHHHCCCCCCCCCCCCCCCCEEECCCEE
IGFPENSFALSSLRDGDAQASLKALAERFFSAPMTVALKVLTGEGHAPPNLLEKKRAEDE
ECCCCCCHHHHHCCCCCHHHHHHHHHHHHHCCCHHHEEEEEECCCCCCHHHHHHHHCHHH
QRRTGLKRSAESHPAVSSALEVFDGTLAEVAPLGTRGKL
HHHHHHHHCCCCCHHHHHHHHHHCCHHHHHCCCCCCCCC
>Mature Secondary Structure 
SYLVLARKWRPQTFSDLTGQEHVSRTLQNAIDSGRIAHAFLFTGARGVGKTSSARILAK
CEEEEECCCCCCCHHHCCCHHHHHHHHHHHHCCCCHHHHHHHHCCCCCCCCHHHHHHHH
ALNCEQGMSPEPCNVCPACTEITAGTSVDVLEIDGASNTGVDDIRELRENVKYLPSRLRY
HHHHCCCCCCCCCCCCCCHHHHCCCCCEEEEEECCCCCCCHHHHHHHHHHHHHHHHHCCE
KIFIIDEVHMLSTNAFNALLKTLEEPPPHVKFIFATTEPHKLPITILSRCQRFDFRRIPL
EEEEEECHHHHHHHHHHHHHHHHCCCCCCEEEEEEECCCCCCHHHHHHHHHHCCCCCCCH
AKVVARLRYIVDREGISISDESLAVVARKGDGSMRDSLSVLDQVLAFCGETVNDDDVVSL
HHHHHHHHHHHHCCCCCCCCCCEEEEEECCCCCHHHHHHHHHHHHHHHCCCCCCHHHHHH
LGVVDRRLLLEASAAVLGRDTRSVLGVVARVDEFGYNMRQFCGELIDHFRNLTIMRAVGD
HHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHCEEHEEECCC
AGDLLDLSEAELQSVREQASSALLEDLQRHMTILLRADGELAHSGYPRLVLEMALVRMAT
CCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHEEEEECCCCHHHCCCHHHHHHHHHHHHHH
LAPLVPVGELLDRLGRIEERGSGVAADARASWRPSPPPEAGVAPVPRPAPSALAEQRPRP
HHCCCCHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHCCCCC
VPAGAEAKPPPSRSDSPVQEPRRTGDEWADFVAFVKGAKPRIGTSLEYGSPLHIAADRLE
CCCCCCCCCCCCCCCCCHHHHHHCHHHHHHHHHHHHCCCCCCCCCCCCCCCCEEECCCEE
IGFPENSFALSSLRDGDAQASLKALAERFFSAPMTVALKVLTGEGHAPPNLLEKKRAEDE
ECCCCCCHHHHHCCCCCHHHHHHHHHHHHHCCCHHHEEEEEECCCCCCHHHHHHHHCHHH
QRRTGLKRSAESHPAVSSALEVFDGTLAEVAPLGTRGKL
HHHHHHHHCCCCCHHHHHHHHHHCCHHHHHCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 2124672; 7584024; 9384377; 2452406; 2468993; 1698458 [H]