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The map label for this gene is dinB [H]

Identifier: 39995154

GI number: 39995154

Start: 52000

End: 53241

Strand: Direct

Name: dinB [H]

Synonym: GSU0043

Alternate gene names: 39995154

Gene position: 52000-53241 (Clockwise)

Preceding gene: 39995153

Following gene: 39995157

Centisome position: 1.36

GC content: 63.12

Gene sequence:

>1242_bases
GTGAGCGGGGGAGAGCCCAGGCAGCGAACCATCCTCCACATCGACATGAACGCCTTTTTCGCCAGTGTCGAACAGCAGGC
GAACCCGAGCCTCCAGGGAAAACCCATCGCCGTTGTCGGCTCCGGCCGCACCGTGGTCACCACCGCCTCCTATGAGGCCC
GGGCCTTCGGCGTCAAGACCGGCATGAACAAGTGGGAAGCGCTCCAGGCCTGCCCCCACCTCATCCTGGTCGTGGGTGAC
AACCGCAAATACACCCACACCTCCACCCAGATCAACCGGATCTTCCGGGACTTCACCCCGGAGGTGGAAACCTTCTCCAT
CGACGAAGCCTTCCTCGACGTCACCGGCTCCCTGGCGCTCTTCGGCTCCGCCGAAACCATCGCCTGCCGGATCAAGGCCC
TGATCCGCCATCGTTTCGGCCTGACCTGCTCCATCGGCATCGCCCCCAACAAGCTCCTCGCCAAACTCGCCTCTGACATG
AAAAAGCCCGACGGCCTCACCATCATCCGCCCGGAAGAGGTGACCCGCCTCATGGAGATCATCCCCATCCAGGACCTCTG
CGGCATCGGCGTCAAGACCAGAAAACAGCTCAACAGCCTCGGCATCCAGACCTGTGGCGAGCTGGGGCGCTTCCCGGTGG
AGATCTTGCGGCGCACATTCGGGGTGATCGGCGACCGGCTCCACCTCATGGGCAAGGGGATCGACGATTCCCCCGTGGTC
CCCGTCGAGGAGGCCGAAGAGGTAAAGAGCGTCGGCCACTCCATGACCCTGGACAGGGACCTCACCGCTCGACGGGACAT
CCTCAAATACCTCCTCCAGCTCTCCGAGATGGTGGGCCGCCGGGCACGGCGCTACGGCGTTGCCGGCAAGACGGTCCATC
TCACCATCCGCTATGCCGACTTCACCACCGTGGGCAAGCAGCAGACCCGGAACCAGGCCACTAACAGCACAGAGGAAATT
TACGCCGAAGCGGTGAAGATCCTCGACACCTTTGAGCTGCTGCAGCCGGTGCGTCTTCTGGGGGTGCGGATCACGAACCT
GTGCTACCAGCGGGAACAGTTGCCGCTCTTCGAGAAGGAACGGAGGAAGGCCCTTGCCACCGGGGCCATGGACGCGGTGA
ACAACAGGTATGGCGACTTCTCTGTCACCTTCGGGAGCCTCCTTGATGAAGAGGAGAAGGGGAGCTTCGTCATCTCCCCG
GCCTGGCGGCCGGAGGGGATCAGGAATGTGGAGGTGAAGTGA

Upstream 100 bases:

>100_bases
CCGTCCTGCGCTTTGCCGTCACCGACGGCAGCTCCCTCTTTGAGCTCTCCTACAACACCCGCGACCAGAACTGGACCCTG
GATGGGGTGGAGGCGGCACC

Downstream 100 bases:

>100_bases
GGATAGGACCGCTTAATCAAGTCATTGCCATGGAAAATGGACTGCACAGGCATGCCTGGAAGTTTTCACCAACGACCAGT
GGCGGAGGGGTGAAGGTCTA

Product: ImpB/MucB/SamB family protein

Products: NA

Alternate protein names: Pol IV [H]

Number of amino acids: Translated: 413; Mature: 412

Protein sequence:

>413_residues
MSGGEPRQRTILHIDMNAFFASVEQQANPSLQGKPIAVVGSGRTVVTTASYEARAFGVKTGMNKWEALQACPHLILVVGD
NRKYTHTSTQINRIFRDFTPEVETFSIDEAFLDVTGSLALFGSAETIACRIKALIRHRFGLTCSIGIAPNKLLAKLASDM
KKPDGLTIIRPEEVTRLMEIIPIQDLCGIGVKTRKQLNSLGIQTCGELGRFPVEILRRTFGVIGDRLHLMGKGIDDSPVV
PVEEAEEVKSVGHSMTLDRDLTARRDILKYLLQLSEMVGRRARRYGVAGKTVHLTIRYADFTTVGKQQTRNQATNSTEEI
YAEAVKILDTFELLQPVRLLGVRITNLCYQREQLPLFEKERRKALATGAMDAVNNRYGDFSVTFGSLLDEEEKGSFVISP
AWRPEGIRNVEVK

Sequences:

>Translated_413_residues
MSGGEPRQRTILHIDMNAFFASVEQQANPSLQGKPIAVVGSGRTVVTTASYEARAFGVKTGMNKWEALQACPHLILVVGD
NRKYTHTSTQINRIFRDFTPEVETFSIDEAFLDVTGSLALFGSAETIACRIKALIRHRFGLTCSIGIAPNKLLAKLASDM
KKPDGLTIIRPEEVTRLMEIIPIQDLCGIGVKTRKQLNSLGIQTCGELGRFPVEILRRTFGVIGDRLHLMGKGIDDSPVV
PVEEAEEVKSVGHSMTLDRDLTARRDILKYLLQLSEMVGRRARRYGVAGKTVHLTIRYADFTTVGKQQTRNQATNSTEEI
YAEAVKILDTFELLQPVRLLGVRITNLCYQREQLPLFEKERRKALATGAMDAVNNRYGDFSVTFGSLLDEEEKGSFVISP
AWRPEGIRNVEVK
>Mature_412_residues
SGGEPRQRTILHIDMNAFFASVEQQANPSLQGKPIAVVGSGRTVVTTASYEARAFGVKTGMNKWEALQACPHLILVVGDN
RKYTHTSTQINRIFRDFTPEVETFSIDEAFLDVTGSLALFGSAETIACRIKALIRHRFGLTCSIGIAPNKLLAKLASDMK
KPDGLTIIRPEEVTRLMEIIPIQDLCGIGVKTRKQLNSLGIQTCGELGRFPVEILRRTFGVIGDRLHLMGKGIDDSPVVP
VEEAEEVKSVGHSMTLDRDLTARRDILKYLLQLSEMVGRRARRYGVAGKTVHLTIRYADFTTVGKQQTRNQATNSTEEIY
AEAVKILDTFELLQPVRLLGVRITNLCYQREQLPLFEKERRKALATGAMDAVNNRYGDFSVTFGSLLDEEEKGSFVISPA
WRPEGIRNVEVK

Specific function: Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by polIV. Exhibits

COG id: COG0389

COG function: function code L; Nucleotidyltransferase/DNA polymerase involved in DNA repair

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 umuC domain [H]

Homologues:

Organism=Homo sapiens, GI84043967, Length=414, Percent_Identity=28.2608695652174, Blast_Score=143, Evalue=2e-34,
Organism=Homo sapiens, GI7706681, Length=415, Percent_Identity=28.1927710843373, Blast_Score=143, Evalue=3e-34,
Organism=Homo sapiens, GI154350220, Length=342, Percent_Identity=30.7017543859649, Blast_Score=141, Evalue=1e-33,
Organism=Homo sapiens, GI7705344, Length=109, Percent_Identity=44.0366972477064, Blast_Score=96, Evalue=5e-20,
Organism=Homo sapiens, GI5729982, Length=125, Percent_Identity=38.4, Blast_Score=74, Evalue=3e-13,
Organism=Escherichia coli, GI1786425, Length=352, Percent_Identity=35.5113636363636, Blast_Score=194, Evalue=7e-51,
Organism=Escherichia coli, GI1787432, Length=227, Percent_Identity=32.15859030837, Blast_Score=109, Evalue=3e-25,
Organism=Caenorhabditis elegans, GI193205700, Length=432, Percent_Identity=26.3888888888889, Blast_Score=121, Evalue=7e-28,
Organism=Caenorhabditis elegans, GI17537959, Length=243, Percent_Identity=29.6296296296296, Blast_Score=105, Evalue=5e-23,
Organism=Caenorhabditis elegans, GI115534089, Length=124, Percent_Identity=37.9032258064516, Blast_Score=82, Evalue=5e-16,
Organism=Caenorhabditis elegans, GI193205702, Length=265, Percent_Identity=27.1698113207547, Blast_Score=81, Evalue=1e-15,
Organism=Drosophila melanogaster, GI21355641, Length=276, Percent_Identity=32.2463768115942, Blast_Score=117, Evalue=1e-26,
Organism=Drosophila melanogaster, GI24644984, Length=276, Percent_Identity=32.2463768115942, Blast_Score=117, Evalue=1e-26,
Organism=Drosophila melanogaster, GI19923006, Length=343, Percent_Identity=25.3644314868805, Blast_Score=108, Evalue=5e-24,
Organism=Drosophila melanogaster, GI24668444, Length=146, Percent_Identity=30.8219178082192, Blast_Score=70, Evalue=2e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR017962
- InterPro:   IPR017961
- InterPro:   IPR001126
- InterPro:   IPR017963
- InterPro:   IPR022880 [H]

Pfam domain/function: PF00817 IMS [H]

EC number: =2.7.7.7 [H]

Molecular weight: Translated: 45967; Mature: 45835

Theoretical pI: Translated: 8.96; Mature: 8.96

Prosite motif: PS50173 UMUC ; PS00216 SUGAR_TRANSPORT_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSGGEPRQRTILHIDMNAFFASVEQQANPSLQGKPIAVVGSGRTVVTTASYEARAFGVKT
CCCCCCCCCEEEEEEHHHHHHHHHHHCCCCCCCCCEEEEECCCEEEEECCCCHHHEEHHH
GMNKWEALQACPHLILVVGDNRKYTHTSTQINRIFRDFTPEVETFSIDEAFLDVTGSLAL
CCCHHHHHHHCCEEEEEEECCCCEECHHHHHHHHHHHCCCCCCEEEHHHHHHHCCCCEEE
FGSAETIACRIKALIRHRFGLTCSIGIAPNKLLAKLASDMKKPDGLTIIRPEEVTRLMEI
ECCCHHHHHHHHHHHHHHCCCEEEECCCCHHHHHHHHHHHCCCCCEEEECHHHHHHHHHH
IPIQDLCGIGVKTRKQLNSLGIQTCGELGRFPVEILRRTFGVIGDRLHLMGKGIDDSPVV
CCHHHHHCCCHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCC
PVEEAEEVKSVGHSMTLDRDLTARRDILKYLLQLSEMVGRRARRYGVAGKTVHLTIRYAD
CHHHHHHHHHCCCCEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEEEEEC
FTTVGKQQTRNQATNSTEEIYAEAVKILDTFELLQPVRLLGVRITNLCYQREQLPLFEKE
CCCCCHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHH
RRKALATGAMDAVNNRYGDFSVTFGSLLDEEEKGSFVISPAWRPEGIRNVEVK
HHHHHHHHHHHHHHCCCCCEEEEHHHHHCCCCCCCEEECCCCCCCCCCCCCCC
>Mature Secondary Structure 
SGGEPRQRTILHIDMNAFFASVEQQANPSLQGKPIAVVGSGRTVVTTASYEARAFGVKT
CCCCCCCCEEEEEEHHHHHHHHHHHCCCCCCCCCEEEEECCCEEEEECCCCHHHEEHHH
GMNKWEALQACPHLILVVGDNRKYTHTSTQINRIFRDFTPEVETFSIDEAFLDVTGSLAL
CCCHHHHHHHCCEEEEEEECCCCEECHHHHHHHHHHHCCCCCCEEEHHHHHHHCCCCEEE
FGSAETIACRIKALIRHRFGLTCSIGIAPNKLLAKLASDMKKPDGLTIIRPEEVTRLMEI
ECCCHHHHHHHHHHHHHHCCCEEEECCCCHHHHHHHHHHHCCCCCEEEECHHHHHHHHHH
IPIQDLCGIGVKTRKQLNSLGIQTCGELGRFPVEILRRTFGVIGDRLHLMGKGIDDSPVV
CCHHHHHCCCHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCC
PVEEAEEVKSVGHSMTLDRDLTARRDILKYLLQLSEMVGRRARRYGVAGKTVHLTIRYAD
CHHHHHHHHHCCCCEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEEEEEC
FTTVGKQQTRNQATNSTEEIYAEAVKILDTFELLQPVRLLGVRITNLCYQREQLPLFEKE
CCCCCHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHH
RRKALATGAMDAVNNRYGDFSVTFGSLLDEEEKGSFVISPAWRPEGIRNVEVK
HHHHHHHHHHHHHHCCCCCEEEEHHHHHCCCCCCCEEECCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA