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The map label for this gene is rnjA [H]

Identifier: 308513338

GI number: 308513338

Start: 3416422

End: 3418107

Strand: Reverse

Name: rnjA [H]

Synonym: NA

Alternate gene names: 308513338

Gene position: 3418107-3416422 (Counterclockwise)

Preceding gene: 39998204

Following gene: 39998202

Centisome position: 89.62

GC content: 62.75

Gene sequence:

>1686_bases
ATGGACACGGCACCCGCTGACATTACGGATAATGGGGGGCTGCGCATCATCCCCCTGGGGGGGCTGGGCGAAATCGGCCT
CAACATGATGGCCTACGAGCACGGCGAGGACATCATCGTCGCCGACTGCGGCCTCATGTTCCCCGAGCCGCAGATGCTCG
GCATCGACCTGGTCATTCCGGATATCACCTACCTGCGGGAACGGGCCGGCCGGGTGCGCGGCATACTCCTCACCCACGGC
CACGAGGACCACATCGGTGCTCTTCCGTATGTCCTTCAGGAGCTCTCGCTCCCTCTCTATGGCACGGCCCTCACCCTTGG
CTTCATTCGGGAAAAACTGAAGGAGTTCGACCTGGAGAGCGAGGTGGAGCTGAATGTCGTCAAGCCCCGCGACGTGGTGA
CGCTCGGCTGCTTCTCCGTGGAGTTCATCAGGGTGTCCCACTCCATCGTGGACGGTTGCGCCCTTGCCATTCGGACCCCG
GAGGGGGTGGTGATCCATACGGGGGACTTCAAGATCGACCAGACCCCGGTGGATGGCGAACTGACCGACCTGGCCACCTT
CTCCCGTTACGGGGACGAGGGGGTTCTGGCGCTCCTGGCCGACTCCACCAACGTGGAGCGCGAGGGGTACACCCTTTCCG
AGCGGGTGGTGGGGGAGGCCTTTGACGAAATTTTCCCCCGCTGCGAGGGGCGGATCATCGTGGCCGCCTTCTCCAGCAAC
ATCCACCGGGTCCAGCAGGCGGTGGACGCGGCGGTCCGCTGTGGCCGCAAGGTATTGCTCAACGGGCGCTCAATGGTGGC
GAACGTGGCCATCGCGCGGCAACTGGGCTACCTGCGGATGCCGGAGGGGGTACTGACCGATCTGAAGGAACTCCAGCACC
TTCCCAAAGAGCAGGTCTGCATGATTACCACCGGTTCCCAGGGCGAGCCCATGAGCTCGCTGGCCCGCATCGCCATGGAC
GATCACAAGCAGATCAAGCTGGAGGCCGGCGACACGGTCATCCTCTCGTCCCGTTTCATCCCGGGCAACGAGAAGACCAT
CTCCGACCTCATCAACCATCTCTATCGCCGGGGGGCCGAGGTCTTTCACGAGAAGGTCTCGGAGGTCCATGTTTCGGGCC
ATGCGTCGCAGGAGGAGCTGAAGCTGATGCTCAACCTCACGCGGCCCCGCCACTTTGTGCCGGTCCACGGAGAATACCGC
CATCTGGTCAAGCATGCCCGGCTGGCACAGCGGGTCGGTGTGCCGGCGGAGCGCTGTCTGGTGGCGGTGAACGGCGACGT
GATCCGCTTCGCTGACGGCCGGGGTGAGATCGCCGGCGCCGTGGAGAGCGGACGGGTCTACATCGACGGTAAGGGAATCG
GCGATGTGGGCGAGGTTGTCCTCAAGGACCGCAAGCACCTGTCCGAGGACGGCATGGTGGTGGTGATCATCGCCATCAAC
CAGGCTTCCGGCGAGGTCATCTACGGGCCGGATATTGTTTCCCGCGGGTTCGTTTTCGAGGACGAAAGCCAGCAGTATCT
GGACGAAACGAAAAAGATCGTCCTGGACCTCCTGGCCGGCATGAGCATCGAAACCCTGGGTGAGTGGGGCGAGGTCAAGC
AGGAAGTGCGACGTATTTTGAGACGCTTCTTCAATAAAACGATAGAACGGCGACCGGTGATCCTGCCGGTTATCCTGGAA
ATGTAG

Upstream 100 bases:
NA

Downstream 100 bases:
NA

Product: metallo-beta-lactamase

Products: NA

Alternate protein names: RNase J1 [H]

Number of amino acids: Translated: 561; Mature: 561

Protein sequence:
NA

Sequences:

>Translated_561_residues
MDTAPADITDNGGLRIIPLGGLGEIGLNMMAYEHGEDIIVADCGLMFPEPQMLGIDLVIPDITYLRERAGRVRGILLTHG
HEDHIGALPYVLQELSLPLYGTALTLGFIREKLKEFDLESEVELNVVKPRDVVTLGCFSVEFIRVSHSIVDGCALAIRTP
EGVVIHTGDFKIDQTPVDGELTDLATFSRYGDEGVLALLADSTNVEREGYTLSERVVGEAFDEIFPRCEGRIIVAAFSSN
IHRVQQAVDAAVRCGRKVLLNGRSMVANVAIARQLGYLRMPEGVLTDLKELQHLPKEQVCMITTGSQGEPMSSLARIAMD
DHKQIKLEAGDTVILSSRFIPGNEKTISDLINHLYRRGAEVFHEKVSEVHVSGHASQEELKLMLNLTRPRHFVPVHGEYR
HLVKHARLAQRVGVPAERCLVAVNGDVIRFADGRGEIAGAVESGRVYIDGKGIGDVGEVVLKDRKHLSEDGMVVVIIAIN
QASGEVIYGPDIVSRGFVFEDESQQYLDETKKIVLDLLAGMSIETLGEWGEVKQEVRRILRRFFNKTIERRPVILPVILE
M
>Mature_561_residues
MDTAPADITDNGGLRIIPLGGLGEIGLNMMAYEHGEDIIVADCGLMFPEPQMLGIDLVIPDITYLRERAGRVRGILLTHG
HEDHIGALPYVLQELSLPLYGTALTLGFIREKLKEFDLESEVELNVVKPRDVVTLGCFSVEFIRVSHSIVDGCALAIRTP
EGVVIHTGDFKIDQTPVDGELTDLATFSRYGDEGVLALLADSTNVEREGYTLSERVVGEAFDEIFPRCEGRIIVAAFSSN
IHRVQQAVDAAVRCGRKVLLNGRSMVANVAIARQLGYLRMPEGVLTDLKELQHLPKEQVCMITTGSQGEPMSSLARIAMD
DHKQIKLEAGDTVILSSRFIPGNEKTISDLINHLYRRGAEVFHEKVSEVHVSGHASQEELKLMLNLTRPRHFVPVHGEYR
HLVKHARLAQRVGVPAERCLVAVNGDVIRFADGRGEIAGAVESGRVYIDGKGIGDVGEVVLKDRKHLSEDGMVVVIIAIN
QASGEVIYGPDIVSRGFVFEDESQQYLDETKKIVLDLLAGMSIETLGEWGEVKQEVRRILRRFFNKTIERRPVILPVILE
M

Specific function: Cleaves the 5'-leader sequence of certain mRNAs. May play a role in maturation and stability of specific mRNAs. Is also required for the maturation of the 16S rRNA. Acts preferentially on 16S rRNA precursors after association of the 30S and 50S ribosomal

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the metallo-beta-lactamase superfamily. RNA-metabolizing metallo-beta-lactamase-like family. RNase J subfamily [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001279
- InterPro:   IPR011108
- InterPro:   IPR004613
- InterPro:   IPR001587 [H]

Pfam domain/function: PF00753 Lactamase_B; PF07521 RMMBL [H]

EC number: NA

Molecular weight: Translated: 61984; Mature: 61984

Theoretical pI: Translated: 5.23; Mature: 5.23

Prosite motif: PS00595 AA_TRANSFER_CLASS_5 ; PS01292 UPF0036

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDTAPADITDNGGLRIIPLGGLGEIGLNMMAYEHGEDIIVADCGLMFPEPQMLGIDLVIP
CCCCCCCCCCCCCEEEEEECCCCHHCCEEEEEECCCEEEEEECCCCCCCCCEEEEEEECC
DITYLRERAGRVRGILLTHGHEDHIGALPYVLQELSLPLYGTALTLGFIREKLKEFDLES
CHHHHHHHCCCEEEEEEECCCCCCCCHHHHHHHHHCCCHHHHHHHHHHHHHHHHHCCCCC
EVELNVVKPRDVVTLGCFSVEFIRVSHSIVDGCALAIRTPEGVVIHTGDFKIDQTPVDGE
CCEEEEECCCCEEEEECCEEEEHHHHHHHHCCEEEEEECCCCEEEECCCEEECCCCCCCC
LTDLATFSRYGDEGVLALLADSTNVEREGYTLSERVVGEAFDEIFPRCEGRIIVAAFSSN
HHHHHHHHHCCCCCEEEEEECCCCCCCCCCCHHHHHHHHHHHHHHHCCCCEEEEEEECCC
IHRVQQAVDAAVRCGRKVLLNGRSMVANVAIARQLGYLRMPEGVLTDLKELQHLPKEQVC
HHHHHHHHHHHHHCCCEEEECCHHHHHHHHHHHHCCCEECCHHHHHHHHHHHHCCCCCEE
MITTGSQGEPMSSLARIAMDDHKQIKLEAGDTVILSSRFIPGNEKTISDLINHLYRRGAE
EEEECCCCCCHHHHHHHHCCCCCEEEEECCCEEEEEEECCCCCCHHHHHHHHHHHHHHHH
VFHEKVSEVHVSGHASQEELKLMLNLTRPRHFVPVHGEYRHLVKHARLAQRVGVPAERCL
HHHHHHHHEEECCCCCHHHHHHHEEECCCCEEEECCCHHHHHHHHHHHHHHHCCCHHHEE
VAVNGDVIRFADGRGEIAGAVESGRVYIDGKGIGDVGEVVLKDRKHLSEDGMVVVIIAIN
EEECCCEEEEECCCCCEEEEEECCEEEECCCCCCHHHHHHHHHHHHCCCCCEEEEEEEEE
QASGEVIYGPDIVSRGFVFEDESQQYLDETKKIVLDLLAGMSIETLGEWGEVKQEVRRIL
CCCCCEEECCCHHCCCCEECCCCHHHHHHHHHHHHHHHCCCCHHHHCCHHHHHHHHHHHH
RRFFNKTIERRPVILPVILEM
HHHHHHHHHCCCEEEEEEECC
>Mature Secondary Structure
MDTAPADITDNGGLRIIPLGGLGEIGLNMMAYEHGEDIIVADCGLMFPEPQMLGIDLVIP
CCCCCCCCCCCCCEEEEEECCCCHHCCEEEEEECCCEEEEEECCCCCCCCCEEEEEEECC
DITYLRERAGRVRGILLTHGHEDHIGALPYVLQELSLPLYGTALTLGFIREKLKEFDLES
CHHHHHHHCCCEEEEEEECCCCCCCCHHHHHHHHHCCCHHHHHHHHHHHHHHHHHCCCCC
EVELNVVKPRDVVTLGCFSVEFIRVSHSIVDGCALAIRTPEGVVIHTGDFKIDQTPVDGE
CCEEEEECCCCEEEEECCEEEEHHHHHHHHCCEEEEEECCCCEEEECCCEEECCCCCCCC
LTDLATFSRYGDEGVLALLADSTNVEREGYTLSERVVGEAFDEIFPRCEGRIIVAAFSSN
HHHHHHHHHCCCCCEEEEEECCCCCCCCCCCHHHHHHHHHHHHHHHCCCCEEEEEEECCC
IHRVQQAVDAAVRCGRKVLLNGRSMVANVAIARQLGYLRMPEGVLTDLKELQHLPKEQVC
HHHHHHHHHHHHHCCCEEEECCHHHHHHHHHHHHCCCEECCHHHHHHHHHHHHCCCCCEE
MITTGSQGEPMSSLARIAMDDHKQIKLEAGDTVILSSRFIPGNEKTISDLINHLYRRGAE
EEEECCCCCCHHHHHHHHCCCCCEEEEECCCEEEEEEECCCCCCHHHHHHHHHHHHHHHH
VFHEKVSEVHVSGHASQEELKLMLNLTRPRHFVPVHGEYRHLVKHARLAQRVGVPAERCL
HHHHHHHHEEECCCCCHHHHHHHEEECCCCEEEECCCHHHHHHHHHHHHHHHCCCHHHEE
VAVNGDVIRFADGRGEIAGAVESGRVYIDGKGIGDVGEVVLKDRKHLSEDGMVVVIIAIN
EEECCCEEEEECCCCCEEEEEECCEEEECCCCCCHHHHHHHHHHHHCCCCCEEEEEEEEE
QASGEVIYGPDIVSRGFVFEDESQQYLDETKKIVLDLLAGMSIETLGEWGEVKQEVRRIL
CCCCCEEECCCHHCCCCEECCCCHHHHHHHHHHHHHHHCCCCHHHHCCHHHHHHHHHHHH
RRFFNKTIERRPVILPVILEM
HHHHHHHHHCCCEEEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8969500; 9384377 [H]