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The map label for this gene is kpsD [H]

Identifier: 308513308

GI number: 308513308

Start: 2008304

End: 2010649

Strand: Reverse

Name: kpsD [H]

Synonym: NA

Alternate gene names: 308513308

Gene position: 2010649-2008304 (Counterclockwise)

Preceding gene: 39996943

Following gene: 39996940

Centisome position: 52.72

GC content: 62.45

Gene sequence:

>2346_bases
ATGGGCTATAACGCAGATCGCAAGCTGGTGCTTTCCTCCGAGGAGGTAAGGGTGATACCCACGGCCCCGGATGCGTCCGC
TTCGTCCCTGGAGCGTGCCTTTGCCCGCCAGAGCCCGACGCTGCTGGACAAGCTCGAACCGACTCCCCTCAACAGATCGC
TCCGTCAGTTCGGGTATGAGTTTTTTAAAAACAGTCTCGCAAGTCTGGCCGTAACTGAAAATCTGCCCGTGGGCCCCGAC
TATGTTGTTGGTCCGGGCGATTCCATCAGAATTGATGTGTGGGGGAGCTTCACCGCCCGCTATGAGCCGACTGTGGACCG
CAACGGCGAGATCCTGATCCCGCGCATTGGTCCGGTAAAGCTCTGGGGGCTGACCTACGGCCAGGCTCGGGAAGCCATAG
ACAAAGCACTGGCCCGCTACTACAAGGGGTACGAGCTGAACGTGACCCTGGGGAGCCTCAGGACCATCCAGGTTTACGTG
GTGGGTGAGGTGGAAACGCCCGGGGTGTACAGTGTCAGCTCCCTGGCCACGGTGGTCAATGCCCTGGCCGCCGCCGGGGG
GCCTTCGAAGAACGGGAGCCTGCGGTCGATCAGGGTGTCGAGACCGGGAGTCGAACCCCGTTCGATCGATCTGTACGACA
TGTTTCTCACTGGTGACCGCAGCAATGACGTGAGGCTGCAAAACGGCGACACGGTATTTGTGCCGGTGATCGGGCCGGTT
GCTGCCGTGGCGGGCGAAGTGCGGCGTCCCGGCATCTACGAGTTGAAGGGCGCGACGCCGCTCGCCCGGCTGGTGGCCAT
GGCGGGGGGGATCACTGCAGCGGGAGATACGGGGCGTATCCAACTGGAGCGGATCGAGGGGAACAGCGCACGGATAGTGC
TCGATTATGAGCCCAAAGGGGGCGACCTGGAGGCCGAACTCGCCCGGGTGGAACTGAAGGACCGTGACATGGTCACCGTG
TTCCCGGTGTTCGATGCCGTGCGCAAGGTGGTCACCCTCACGGGGAACGTGACGCGGCCCGGTGCCTATCAGTTGAAGGA
GGGAATGCGGGTCAGGGATATTCTTCCTGATCCGTCGGTCCTTCTCCCCGAATCGTATCTGGAGTCGGCCGAGATTACCC
GTCTTGCTCTTCCCGAGTACCGCCGGGAAGTGGTCACCTTCAATCTGCGGGCCGCCATGCAGGGGGATCCCAAGGAGAAC
CTTCCCCTTCAGGAGCAGGACACGGTGCGGGTGTTCTCCCGGGCCGAGATGATTGAGAAGCATACGGTGTCCATCAGCGG
GGCGGTGCTCAATCCGGGCAGCTATGAGTATTTTCCGCGCATGACGGTGCGCGACCTGGTGACCGTCGCCGGCAGTCCCA
AGCGAAATGCTTTTCTGGGCAGTGCGGAGCTGACCAGGATCAATGTCAACGGCGACGGAGCGCGGGCGAGTAGGCAGGAT
ATCAATCTCGAAAAGGCCATGGCGGGCGATCCCGATCATAACCTCCCCCTGCAGACCGACGACGTCCTCATCGTCCGGAG
CATCGAGAACTGGCTTGAGGCCAGCGACCGGTTCGTGACCCTGCGGGGCGAGGTGAAGTTTCCCGGCACCTATTCCATTG
CCAAGGGAGAACGACTGAGTTCGGTCATTGCCCGGGCCGGGGGCTATACCGAACATTCCTGCCTGAAGGGGGCCAAGTTC
ACCCGCCGGTCGGTCAGAGAGGAGCAGCAGCGCCGCATGGACGAGGTGATCGCCCGGACCGAGCAGGATGTCTACCGCAA
GCAGGCGGAACTCTCGTCGGTGGCTACATCACGCGAGGAGCTGGAGGCCACCAAGGCCGCCCTCGACGGTCTGTTGCGGA
GTCTGGCGAAGCTGAAGACCACCAGGGCCGAGGGGCGGGTGGTGATCCGGCTGGCGCCGGTCGAGGCGCTTGCCCACAGC
TCCTATGACCTTGAACTGGAAGGCGGGGATGAACTCTCCATACCCCCAACCCCGAGCGTGGTGTCGGTCATGGGGTCCGT
CTACAACCCCACGTCGTTCCTGCACATTTCAGAGCGGGACGTGGCCTATTACCTGGAACGTTCCGGCGGGGCTACCCGTG
ATGCCGAATTGGATGACATGTACATTATCAAGGCCGACGGATCGGTCTTCAGCAGGCAGCAATCGTCCTTCGGCATTCGC
TGGGACGACTATGCCCGGCGCTGGACGTTCGGCGGATTCCTGTCGTCCCCCCTGGAGCCCGGAGATACGCTCGTGGTGCC
GCAGAAGCTCGAGCGAACCGCCTGGATGCGCGAGATCAAGGACATAACAACCATCCTGTCGCAGGTAGCCATAACCGCCG
GCGTGATCATCGCGGCAGGTCTCTAG

Upstream 100 bases:
NA

Downstream 100 bases:
NA

Product: polysaccharide biosynthesis/export domain-containing protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 781; Mature: 780

Protein sequence:
NA

Sequences:

>Translated_781_residues
MGYNADRKLVLSSEEVRVIPTAPDASASSLERAFARQSPTLLDKLEPTPLNRSLRQFGYEFFKNSLASLAVTENLPVGPD
YVVGPGDSIRIDVWGSFTARYEPTVDRNGEILIPRIGPVKLWGLTYGQAREAIDKALARYYKGYELNVTLGSLRTIQVYV
VGEVETPGVYSVSSLATVVNALAAAGGPSKNGSLRSIRVSRPGVEPRSIDLYDMFLTGDRSNDVRLQNGDTVFVPVIGPV
AAVAGEVRRPGIYELKGATPLARLVAMAGGITAAGDTGRIQLERIEGNSARIVLDYEPKGGDLEAELARVELKDRDMVTV
FPVFDAVRKVVTLTGNVTRPGAYQLKEGMRVRDILPDPSVLLPESYLESAEITRLALPEYRREVVTFNLRAAMQGDPKEN
LPLQEQDTVRVFSRAEMIEKHTVSISGAVLNPGSYEYFPRMTVRDLVTVAGSPKRNAFLGSAELTRINVNGDGARASRQD
INLEKAMAGDPDHNLPLQTDDVLIVRSIENWLEASDRFVTLRGEVKFPGTYSIAKGERLSSVIARAGGYTEHSCLKGAKF
TRRSVREEQQRRMDEVIARTEQDVYRKQAELSSVATSREELEATKAALDGLLRSLAKLKTTRAEGRVVIRLAPVEALAHS
SYDLELEGGDELSIPPTPSVVSVMGSVYNPTSFLHISERDVAYYLERSGGATRDAELDDMYIIKADGSVFSRQQSSFGIR
WDDYARRWTFGGFLSSPLEPGDTLVVPQKLERTAWMREIKDITTILSQVAITAGVIIAAGL
>Mature_780_residues
GYNADRKLVLSSEEVRVIPTAPDASASSLERAFARQSPTLLDKLEPTPLNRSLRQFGYEFFKNSLASLAVTENLPVGPDY
VVGPGDSIRIDVWGSFTARYEPTVDRNGEILIPRIGPVKLWGLTYGQAREAIDKALARYYKGYELNVTLGSLRTIQVYVV
GEVETPGVYSVSSLATVVNALAAAGGPSKNGSLRSIRVSRPGVEPRSIDLYDMFLTGDRSNDVRLQNGDTVFVPVIGPVA
AVAGEVRRPGIYELKGATPLARLVAMAGGITAAGDTGRIQLERIEGNSARIVLDYEPKGGDLEAELARVELKDRDMVTVF
PVFDAVRKVVTLTGNVTRPGAYQLKEGMRVRDILPDPSVLLPESYLESAEITRLALPEYRREVVTFNLRAAMQGDPKENL
PLQEQDTVRVFSRAEMIEKHTVSISGAVLNPGSYEYFPRMTVRDLVTVAGSPKRNAFLGSAELTRINVNGDGARASRQDI
NLEKAMAGDPDHNLPLQTDDVLIVRSIENWLEASDRFVTLRGEVKFPGTYSIAKGERLSSVIARAGGYTEHSCLKGAKFT
RRSVREEQQRRMDEVIARTEQDVYRKQAELSSVATSREELEATKAALDGLLRSLAKLKTTRAEGRVVIRLAPVEALAHSS
YDLELEGGDELSIPPTPSVVSVMGSVYNPTSFLHISERDVAYYLERSGGATRDAELDDMYIIKADGSVFSRQQSSFGIRW
DDYARRWTFGGFLSSPLEPGDTLVVPQKLERTAWMREIKDITTILSQVAITAGVIIAAGL

Specific function: Involved in the translocation of the polysialic acid capsule across the outer membrane to the cell surface. May function as the periplasmic binding element of the PSA transport system, in which it transiently interacts with the membrane component of the t

COG id: NA

COG function: NA

Gene ontology:

Cell location: Periplasm [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: To E.coli K5 kpsD [H]

Homologues:

Organism=Escherichia coli, GI1787218, Length=168, Percent_Identity=27.3809523809524, Blast_Score=71, Evalue=2e-13,
Organism=Escherichia coli, GI1788376, Length=227, Percent_Identity=25.9911894273128, Blast_Score=70, Evalue=4e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003715 [H]

Pfam domain/function: PF02563 Poly_export [H]

EC number: NA

Molecular weight: Translated: 85707; Mature: 85576

Theoretical pI: Translated: 5.62; Mature: 5.62

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.1 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
1.8 %Cys+Met (Translated Protein)
0.1 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
1.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGYNADRKLVLSSEEVRVIPTAPDASASSLERAFARQSPTLLDKLEPTPLNRSLRQFGYE
CCCCCCCEEEEECCCEEEEECCCCCCHHHHHHHHHHCCCCHHHCCCCCCCCHHHHHHHHH
FFKNSLASLAVTENLPVGPDYVVGPGDSIRIDVWGSFTARYEPTVDRNGEILIPRIGPVK
HHHHHHHHEEEECCCCCCCCEEECCCCEEEEEEEECEEEEECCCCCCCCCEEEECCCCEE
LWGLTYGQAREAIDKALARYYKGYELNVTLGSLRTIQVYVVGEVETPGVYSVSSLATVVN
EEECCHHHHHHHHHHHHHHHHCCEEEEEEECCCEEEEEEEEEECCCCCCCHHHHHHHHHH
ALAAAGGPSKNGSLRSIRVSRPGVEPRSIDLYDMFLTGDRSNDVRLQNGDTVFVPVIGPV
HHHHCCCCCCCCCEEEEEECCCCCCCCCEEEEEEEEECCCCCCEEEECCCEEEEECCHHH
AAVAGEVRRPGIYELKGATPLARLVAMAGGITAAGDTGRIQLERIEGNSARIVLDYEPKG
HHHHHHHCCCCCEEECCCCHHHHHHHHHCCCEECCCCCEEEEEEECCCCEEEEEEECCCC
GDLEAELARVELKDRDMVTVFPVFDAVRKVVTLTGNVTRPGAYQLKEGMRVRDILPDPSV
CCCCEEEEEEEECCCCEEEEEHHHHHHHHHEEECCCCCCCCHHHHHCCCEEECCCCCCCE
LLPESYLESAEITRLALPEYRREVVTFNLRAAMQGDPKENLPLQEQDTVRVFSRAEMIEK
ECCHHHHCHHHHHHHHCHHHHHEEEEEEEEEEECCCCCCCCCCCCCHHHHHHHHHHHHHH
HTVSISGAVLNPGSYEYFPRMTVRDLVTVAGSPKRNAFLGSAELTRINVNGDGARASRQD
HEEEEEEEEECCCCCCCCCCCHHHHHHHHCCCCCCCEEECCCEEEEEEECCCCCCCCHHC
INLEKAMAGDPDHNLPLQTDDVLIVRSIENWLEASDRFVTLRGEVKFPGTYSIAKGERLS
CCHHHHHCCCCCCCCCCCCCCEEEEEHHHHHHCCCCCEEEEEEEEECCCCEECCCCHHHH
SVIARAGGYTEHSCLKGAKFTRRSVREEQQRRMDEVIARTEQDVYRKQAELSSVATSREE
HHHHHCCCCCHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LEATKAALDGLLRSLAKLKTTRAEGRVVIRLAPVEALAHSSYDLELEGGDELSIPPTPSV
HHHHHHHHHHHHHHHHHHHHCCCCCEEEEEEECHHHHHCCCCEEEECCCCCCCCCCCCHH
VSVMGSVYNPTSFLHISERDVAYYLERSGGATRDAELDDMYIIKADGSVFSRQQSSFGIR
HHHHHCCCCCCEEEEECCCCEEEEEECCCCCCCCCCCCCEEEEEECCCHHHCHHHCCCCC
WDDYARRWTFGGFLSSPLEPGDTLVVPQKLERTAWMREIKDITTILSQVAITAGVIIAAG
CHHHHHHEECCCHHCCCCCCCCEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHCEEEEEC
L
C
>Mature Secondary Structure 
GYNADRKLVLSSEEVRVIPTAPDASASSLERAFARQSPTLLDKLEPTPLNRSLRQFGYE
CCCCCCEEEEECCCEEEEECCCCCCHHHHHHHHHHCCCCHHHCCCCCCCCHHHHHHHHH
FFKNSLASLAVTENLPVGPDYVVGPGDSIRIDVWGSFTARYEPTVDRNGEILIPRIGPVK
HHHHHHHHEEEECCCCCCCCEEECCCCEEEEEEEECEEEEECCCCCCCCCEEEECCCCEE
LWGLTYGQAREAIDKALARYYKGYELNVTLGSLRTIQVYVVGEVETPGVYSVSSLATVVN
EEECCHHHHHHHHHHHHHHHHCCEEEEEEECCCEEEEEEEEEECCCCCCCHHHHHHHHHH
ALAAAGGPSKNGSLRSIRVSRPGVEPRSIDLYDMFLTGDRSNDVRLQNGDTVFVPVIGPV
HHHHCCCCCCCCCEEEEEECCCCCCCCCEEEEEEEEECCCCCCEEEECCCEEEEECCHHH
AAVAGEVRRPGIYELKGATPLARLVAMAGGITAAGDTGRIQLERIEGNSARIVLDYEPKG
HHHHHHHCCCCCEEECCCCHHHHHHHHHCCCEECCCCCEEEEEEECCCCEEEEEEECCCC
GDLEAELARVELKDRDMVTVFPVFDAVRKVVTLTGNVTRPGAYQLKEGMRVRDILPDPSV
CCCCEEEEEEEECCCCEEEEEHHHHHHHHHEEECCCCCCCCHHHHHCCCEEECCCCCCCE
LLPESYLESAEITRLALPEYRREVVTFNLRAAMQGDPKENLPLQEQDTVRVFSRAEMIEK
ECCHHHHCHHHHHHHHCHHHHHEEEEEEEEEEECCCCCCCCCCCCCHHHHHHHHHHHHHH
HTVSISGAVLNPGSYEYFPRMTVRDLVTVAGSPKRNAFLGSAELTRINVNGDGARASRQD
HEEEEEEEEECCCCCCCCCCCHHHHHHHHCCCCCCCEEECCCEEEEEEECCCCCCCCHHC
INLEKAMAGDPDHNLPLQTDDVLIVRSIENWLEASDRFVTLRGEVKFPGTYSIAKGERLS
CCHHHHHCCCCCCCCCCCCCCEEEEEHHHHHHCCCCCEEEEEEEEECCCCEECCCCHHHH
SVIARAGGYTEHSCLKGAKFTRRSVREEQQRRMDEVIARTEQDVYRKQAELSSVATSREE
HHHHHCCCCCHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LEATKAALDGLLRSLAKLKTTRAEGRVVIRLAPVEALAHSSYDLELEGGDELSIPPTPSV
HHHHHHHHHHHHHHHHHHHHCCCCCEEEEEEECHHHHHCCCCEEEECCCCCCCCCCCCHH
VSVMGSVYNPTSFLHISERDVAYYLERSGGATRDAELDDMYIIKADGSVFSRQQSSFGIR
HHHHHCCCCCCEEEEECCCCEEEEEECCCCCCCCCCCCCEEEEEECCCHHHCHHHCCCCC
WDDYARRWTFGGFLSSPLEPGDTLVVPQKLERTAWMREIKDITTILSQVAITAGVIIAAG
CHHHHHHEECCCHHCCCCCCCCEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHCEEEEEC
L
C

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8021185 [H]