Click here to switch to the map view.

The map label for this gene is ywcA [H]

Identifier: 308513294

GI number: 308513294

Start: 1158814

End: 1160568

Strand: Reverse

Name: ywcA [H]

Synonym: NA

Alternate gene names: 308513294

Gene position: 1160568-1158814 (Counterclockwise)

Preceding gene: 39996173

Following gene: 39996171

Centisome position: 30.43

GC content: 63.42

Gene sequence:

>1755_bases
ATGGTCACCATCCCCATCTTCCTGATCATCATCGGCGCCACCATGGCCGTTGTCGTCTGGTCGGCCAAGCGGACCAAGTC
GGCCGCCGACTTCTACACCGCCGGCGGCGGCATCACCGGCACCCAGAACGGTTGGGCCATCGCGGGCGACTACATGTCCG
CCGCCTCCTTCCTGGGGATTTCGGGCATGATCTCCCTCTACGGCTATGACGGGTTCATGTACTCGGTGGGTTGGCTCGTG
GCCTACATCACGGTGCTCCTGATCGTGGCAGAGCCCTGCCGCAACGCGGGCAAGTACACCCTGGGCGACATCCTCTCCTT
CCGCACCGAGCCCAAGGTCGTCCGGGCCGTTTGCGCCATCTCCGTCGTTGCCGTCTCCACCTTCTACCTGACCGCTCAGA
TGGTCGGTGCCGGCAAGCTGATGCAGCTGTTGCTCGGGATTCCCTACAAGTTCGCCATCATCGGCGTCGGCATCCTCATG
GTCGGCTACGTCGTGTTCGGCGGCATGACCGCCACCACCTGGGTTCAGATCATCAAGGCCGGCCTCCTCATGACCGGTGC
GGGCCTCCTCTCCGTCCTGGTCGGCCTCAAGGCCGGCATGAACCCGTTCACCTTCTTCAACGACATCGCCACTAACCCCA
ACATCATCGAGCACGTCCAGAAGGCCGTTCTCAAGGACCCCGTTGCCGTGGCGGGCTTCGATTACGGGCAGCGCTTCCTT
GAGCCGGGCCTCTTCCTGAAGAACCCGCTCGACCAGATCTCCCTCGGCATGGCACTGGTGCTCGGAACCGCCGGCATGCC
CCACATCCTGATGCGCTTCTTCACCGTGCCCACGGCCCAGGCCGCCCGCAAGTCCGTTATCGTGGCCATGTTCATCATTG
GCTCCTTCTACATCCTGACCACGCTTCTCGGCTTCGGCGCCGCCATCCACGTGACCCCGCAAGGGATCACCGCCGTTGAC
AAGGGCGGGAACATGGCCGCCATGATGCTGGCCCAGCAACTGGGCGGCGACATCTCCCCCTTCCTGGGCGACCTGCTCCT
GGCGTTCCTGTGCGCCGTTGCCTTCGCCACCATCCTCGCCGTCGTGTCGGGTCTCGTTCTGGCCGCTTCCGCCGCCATTG
CCCACGACATCTACGTAAACGTCATCAAGGACGGCCACGCCGACCAGCACGAGCAGGTCATGGCCGCCCGGATCACCTCC
CTGTGCGTCGGCGCCATGGGCATCATCATCGGCATCGCCGCCGAGAAGCAGAACGTCGCCCACCTGGTGGCCCTGGCCTT
CGCCGTTGCCTCCTCGGGCAACCTGCCGGTCGTAGTCATGTCCCTCTTCTGGCGGAAGTTCAATACCGCCGGCGTCGTGT
CGGGCCTCGTGGTCGGCACCGTCGCCTCCATCGCACTGGTGATGGTCTCCCCCAACATGACCTATCCGAAGGTCGTTGCC
GCCGACGCCCAAAAAGTCGTCACGAAGCTTGAAGAGAAACAGGCCGGTGGTGCGGTCCTCACCGAAAAGGAAATGAAGGA
CCTTGACAAGGCAAAGGCCGACTACGCCAAGAACAAGGACGGCAAGTCCATGCTGGGCCTTGACAAGCCGCTGATCAAAC
TTAAGAACCCGGGCATCATCTCGATCCCGCTGGGCTTCCTCGCCGCCATCATCGGCTGCCTGGCCTTCCCGAGCCGGCGT
TCCGAGGAAATGTTCGACGAGATCTACGTCCGCCAGAACACCGGCATCGGCATGGCCAAGGCCATCGATCACTAG

Upstream 100 bases:
NA

Downstream 100 bases:
NA

Product: sodium/solute symporter family protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 584; Mature: 584

Protein sequence:
NA

Sequences:

>Translated_584_residues
MVTIPIFLIIIGATMAVVVWSAKRTKSAADFYTAGGGITGTQNGWAIAGDYMSAASFLGISGMISLYGYDGFMYSVGWLV
AYITVLLIVAEPCRNAGKYTLGDILSFRTEPKVVRAVCAISVVAVSTFYLTAQMVGAGKLMQLLLGIPYKFAIIGVGILM
VGYVVFGGMTATTWVQIIKAGLLMTGAGLLSVLVGLKAGMNPFTFFNDIATNPNIIEHVQKAVLKDPVAVAGFDYGQRFL
EPGLFLKNPLDQISLGMALVLGTAGMPHILMRFFTVPTAQAARKSVIVAMFIIGSFYILTTLLGFGAAIHVTPQGITAVD
KGGNMAAMMLAQQLGGDISPFLGDLLLAFLCAVAFATILAVVSGLVLAASAAIAHDIYVNVIKDGHADQHEQVMAARITS
LCVGAMGIIIGIAAEKQNVAHLVALAFAVASSGNLPVVVMSLFWRKFNTAGVVSGLVVGTVASIALVMVSPNMTYPKVVA
ADAQKVVTKLEEKQAGGAVLTEKEMKDLDKAKADYAKNKDGKSMLGLDKPLIKLKNPGIISIPLGFLAAIIGCLAFPSRR
SEEMFDEIYVRQNTGIGMAKAIDH
>Mature_584_residues
MVTIPIFLIIIGATMAVVVWSAKRTKSAADFYTAGGGITGTQNGWAIAGDYMSAASFLGISGMISLYGYDGFMYSVGWLV
AYITVLLIVAEPCRNAGKYTLGDILSFRTEPKVVRAVCAISVVAVSTFYLTAQMVGAGKLMQLLLGIPYKFAIIGVGILM
VGYVVFGGMTATTWVQIIKAGLLMTGAGLLSVLVGLKAGMNPFTFFNDIATNPNIIEHVQKAVLKDPVAVAGFDYGQRFL
EPGLFLKNPLDQISLGMALVLGTAGMPHILMRFFTVPTAQAARKSVIVAMFIIGSFYILTTLLGFGAAIHVTPQGITAVD
KGGNMAAMMLAQQLGGDISPFLGDLLLAFLCAVAFATILAVVSGLVLAASAAIAHDIYVNVIKDGHADQHEQVMAARITS
LCVGAMGIIIGIAAEKQNVAHLVALAFAVASSGNLPVVVMSLFWRKFNTAGVVSGLVVGTVASIALVMVSPNMTYPKVVA
ADAQKVVTKLEEKQAGGAVLTEKEMKDLDKAKADYAKNKDGKSMLGLDKPLIKLKNPGIISIPLGFLAAIIGCLAFPSRR
SEEMFDEIYVRQNTGIGMAKAIDH

Specific function: Unknown

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family [H]

Homologues:

Organism=Escherichia coli, GI1790503, Length=594, Percent_Identity=39.0572390572391, Blast_Score=392, Evalue=1e-110,
Organism=Escherichia coli, GI1787251, Length=452, Percent_Identity=23.2300884955752, Blast_Score=74, Evalue=2e-14,
Organism=Escherichia coli, GI87082237, Length=436, Percent_Identity=22.4770642201835, Blast_Score=69, Evalue=9e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001734
- InterPro:   IPR018212
- InterPro:   IPR019900 [H]

Pfam domain/function: PF00474 SSF [H]

EC number: NA

Molecular weight: Translated: 61523; Mature: 61523

Theoretical pI: Translated: 9.27; Mature: 9.27

Prosite motif: PS00456 NA_SOLUT_SYMP_1 ; PS50283 NA_SOLUT_SYMP_3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
4.6 %Met     (Translated Protein)
5.5 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
4.6 %Met     (Mature Protein)
5.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure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EECHHHHHHHHHHHCCCCCCHHHHHHHHHHCCCCCCCHHHHCCC
>Mature Secondary Structure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EECHHHHHHHHHHHCCCCCCHHHHHHHHHHCCCCCCCHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 7934828; 9384377 [H]