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The map label for this gene is resE [H]

Identifier: 57235028

GI number: 57235028

Start: 133577

End: 135322

Strand: Direct

Name: resE [H]

Synonym: DET0136

Alternate gene names: 57235028

Gene position: 133577-135322 (Clockwise)

Preceding gene: 57235029

Following gene: 57235021

Centisome position: 9.09

GC content: 53.09

Gene sequence:

>1746_bases
ATGGCCAGAAGCCTTAAATGGCGTTTAATAAGCCTGTTTTGCCTGCTTATTGCCGCTAGCGTGGGTCTGCTCAGCATTTT
CCTGTCCAATCATCTGGAGAACTCTTATCTGGACAATTTGCAGTCCCGCCTTGTTCAGGAAGCCACGCTGCTTTCAGAGA
TAGTGCCGGAGCATATTTCTGAAGACCCGGACAGTTTTGATGCTTATATTAAGGAACTGGGAGCCTCGCTGGATATACGG
CTGACTGTTATAGACCCCGGCGGTCAGGTGCTGGCAGATTCACTCCAGTCACCCTCGGACATGGAGAATCACTCTACCAG
AGTTGAGTTTATTGATGCTTTAAAAAACGGCCTTGGCACCAGTGTTCATCAGTCTGCCAGTCTGGGATATGAAATGCTGT
ACGTGGCTATCCCGGTTAAAAGCGGGACAGAGGTACTGGCGGTAGTGCGGGTGGCCTTGCCGGTAGAAGAAGTATACGCG
GCGGTGGGGGATGTAGACCGGACTATTTTGCTGAGTGCCTTAATAAGCATACTGGCGGCCGGGCTTTTAGCAGTTTGGGT
AGCGGCCAGCCTGACCCGCCCGATTAAGGAACTCACCGCTATTGCCCGGCGTATTGCCCGGGGGCAGATGGATGCCGTTC
AGATAGAGGTAAGCGGCAAAGGTGAAATGGAAGAACTGGCCCATGCCTTCCGCCTGATGACGGAACGCCTGCGTGACAGC
ATAAATGCAGTCAGCTCCGAGCGTGACCGCCTGTCAGCGGTACTGGAACGCATGGGTGACGGCATTTTCCTGCTGGACTG
CGAAGGCACTATAAGCCTTTTAAACCCGGCTGCCGAGCGGATATTTAAACTGGAAGCCGAACATGTAATAGGCCACAGCT
TTGTGGAAGCAATACGTGACCATGAAATCCACTCTATTTTTGAGCATTCCAAATCCTCCGGCAAGCAGGAGATGGGTTTT
GTAGAGCTTGCCTCCGGCAGGCGTTTTCTGGGTATTATTGCTACCCCGCTGGTCAGCCAGTCCGGTTATCTGGTGCTGGT
GCAGGACCTTTCAGAGCTTCGGCGGCTGGAGAAGGTAAGGCGGGATTTTGTAGCCAATATTTCCCACGAATTACGCACCC
CTATCAGTTCCCTGAAACTGCTGACTGAAACCTTGCAGGAGGGGGCGGCATCTGATGCTGCGGTTGCGGCCGGGTTTATT
GAAAAAATCCACCTTGAGGTAGATAAACTGGCCCAGCTGGTTACCGAACTGAGTGACCTTTCCGCTATAGAAAGCGGCCA
GGCGGTTTTAAACCTCCAGCCGGGAGATATTTCCACAGCTATAAAACTGGCAGCCGCCAGGCTTAGCCCCCAGGCGGAAC
GGGCAGGTATAAGCCTTGGGGTAGAACTGCCCGAAACCCTGCCGCAGGTAAAGCTGGACGAAAACCGGATTGAACAAGTG
CTGGTAAATCTGGTGCATAATGCCATCAAGTTTACCCCCAAGGGCGGCCGGATAAAGATTGGTGCCCGCACCCAGGGGCA
GATACTGGTAGTATATGTATCTGACAGCGGCATAGGTATACCCGAAGATGATTTGACCAGAGTATTTGAGCGTTTTTACA
AAGTGGATAAAGCCCGTTCCGGCGGCGGTACAGGTTTGGGACTGGCTATTTCCAAGCATATAGTGCAGGCACACGGCGGG
AACATCTGGGCAGAAAGCCGCTACGGCAAGGGGGCAACCTTCAGTTTCAGCCTGCCGCTTGGCTGA

Upstream 100 bases:

>100_bases
TACATATCAGCTGGCTGCGCCAGAAAATAGAGACTGACCCGTCCCGTCCCCGCCACCTGATAACAGTGCGGGGAACCGGC
TATAAGTTTGAGGAGTAAAT

Downstream 100 bases:

>100_bases
GTATTTTCTTACACCCGTTAGTTTATAAACCAGCTCTATCAGGGCTGGTTTTTTTATTATTCCGGTATTTCAAGATTTTT
ACATAACCTTAACAAATCCT

Product: sensory box sensor histidine kinase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 581; Mature: 580

Protein sequence:

>581_residues
MARSLKWRLISLFCLLIAASVGLLSIFLSNHLENSYLDNLQSRLVQEATLLSEIVPEHISEDPDSFDAYIKELGASLDIR
LTVIDPGGQVLADSLQSPSDMENHSTRVEFIDALKNGLGTSVHQSASLGYEMLYVAIPVKSGTEVLAVVRVALPVEEVYA
AVGDVDRTILLSALISILAAGLLAVWVAASLTRPIKELTAIARRIARGQMDAVQIEVSGKGEMEELAHAFRLMTERLRDS
INAVSSERDRLSAVLERMGDGIFLLDCEGTISLLNPAAERIFKLEAEHVIGHSFVEAIRDHEIHSIFEHSKSSGKQEMGF
VELASGRRFLGIIATPLVSQSGYLVLVQDLSELRRLEKVRRDFVANISHELRTPISSLKLLTETLQEGAASDAAVAAGFI
EKIHLEVDKLAQLVTELSDLSAIESGQAVLNLQPGDISTAIKLAAARLSPQAERAGISLGVELPETLPQVKLDENRIEQV
LVNLVHNAIKFTPKGGRIKIGARTQGQILVVYVSDSGIGIPEDDLTRVFERFYKVDKARSGGGTGLGLAISKHIVQAHGG
NIWAESRYGKGATFSFSLPLG

Sequences:

>Translated_581_residues
MARSLKWRLISLFCLLIAASVGLLSIFLSNHLENSYLDNLQSRLVQEATLLSEIVPEHISEDPDSFDAYIKELGASLDIR
LTVIDPGGQVLADSLQSPSDMENHSTRVEFIDALKNGLGTSVHQSASLGYEMLYVAIPVKSGTEVLAVVRVALPVEEVYA
AVGDVDRTILLSALISILAAGLLAVWVAASLTRPIKELTAIARRIARGQMDAVQIEVSGKGEMEELAHAFRLMTERLRDS
INAVSSERDRLSAVLERMGDGIFLLDCEGTISLLNPAAERIFKLEAEHVIGHSFVEAIRDHEIHSIFEHSKSSGKQEMGF
VELASGRRFLGIIATPLVSQSGYLVLVQDLSELRRLEKVRRDFVANISHELRTPISSLKLLTETLQEGAASDAAVAAGFI
EKIHLEVDKLAQLVTELSDLSAIESGQAVLNLQPGDISTAIKLAAARLSPQAERAGISLGVELPETLPQVKLDENRIEQV
LVNLVHNAIKFTPKGGRIKIGARTQGQILVVYVSDSGIGIPEDDLTRVFERFYKVDKARSGGGTGLGLAISKHIVQAHGG
NIWAESRYGKGATFSFSLPLG
>Mature_580_residues
ARSLKWRLISLFCLLIAASVGLLSIFLSNHLENSYLDNLQSRLVQEATLLSEIVPEHISEDPDSFDAYIKELGASLDIRL
TVIDPGGQVLADSLQSPSDMENHSTRVEFIDALKNGLGTSVHQSASLGYEMLYVAIPVKSGTEVLAVVRVALPVEEVYAA
VGDVDRTILLSALISILAAGLLAVWVAASLTRPIKELTAIARRIARGQMDAVQIEVSGKGEMEELAHAFRLMTERLRDSI
NAVSSERDRLSAVLERMGDGIFLLDCEGTISLLNPAAERIFKLEAEHVIGHSFVEAIRDHEIHSIFEHSKSSGKQEMGFV
ELASGRRFLGIIATPLVSQSGYLVLVQDLSELRRLEKVRRDFVANISHELRTPISSLKLLTETLQEGAASDAAVAAGFIE
KIHLEVDKLAQLVTELSDLSAIESGQAVLNLQPGDISTAIKLAAARLSPQAERAGISLGVELPETLPQVKLDENRIEQVL
VNLVHNAIKFTPKGGRIKIGARTQGQILVVYVSDSGIGIPEDDLTRVFERFYKVDKARSGGGTGLGLAISKHIVQAHGGN
IWAESRYGKGATFSFSLPLG

Specific function: Member of the two-component regulatory system resD/resE involved in the global regulation of aerobic and anaerobic respiration. Probably phosphorylates resD [H]

COG id: COG0642

COG function: function code T; Signal transduction histidine kinase

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PAS (PER-ARNT-SIM) domain [H]

Homologues:

Organism=Escherichia coli, GI1786600, Length=375, Percent_Identity=29.8666666666667, Blast_Score=139, Evalue=4e-34,
Organism=Escherichia coli, GI48994928, Length=292, Percent_Identity=30.4794520547945, Blast_Score=132, Evalue=6e-32,
Organism=Escherichia coli, GI1788393, Length=241, Percent_Identity=32.7800829875519, Blast_Score=130, Evalue=3e-31,
Organism=Escherichia coli, GI1790436, Length=237, Percent_Identity=35.8649789029536, Blast_Score=115, Evalue=5e-27,
Organism=Escherichia coli, GI1789149, Length=242, Percent_Identity=32.6446280991736, Blast_Score=114, Evalue=2e-26,
Organism=Escherichia coli, GI1786912, Length=225, Percent_Identity=33.7777777777778, Blast_Score=110, Evalue=3e-25,
Organism=Escherichia coli, GI145693157, Length=228, Percent_Identity=34.2105263157895, Blast_Score=103, Evalue=2e-23,
Organism=Escherichia coli, GI1788713, Length=268, Percent_Identity=30.5970149253731, Blast_Score=103, Evalue=3e-23,
Organism=Escherichia coli, GI1788549, Length=382, Percent_Identity=23.0366492146597, Blast_Score=102, Evalue=6e-23,
Organism=Escherichia coli, GI87081816, Length=239, Percent_Identity=31.3807531380753, Blast_Score=99, Evalue=6e-22,
Organism=Escherichia coli, GI1786783, Length=232, Percent_Identity=29.7413793103448, Blast_Score=97, Evalue=4e-21,
Organism=Escherichia coli, GI1790346, Length=237, Percent_Identity=29.1139240506329, Blast_Score=93, Evalue=4e-20,
Organism=Escherichia coli, GI1790861, Length=200, Percent_Identity=30.5, Blast_Score=91, Evalue=2e-19,
Organism=Escherichia coli, GI1790300, Length=366, Percent_Identity=25.4098360655738, Blast_Score=82, Evalue=1e-16,
Organism=Escherichia coli, GI1787894, Length=226, Percent_Identity=27.8761061946903, Blast_Score=81, Evalue=2e-16,
Organism=Escherichia coli, GI1788279, Length=239, Percent_Identity=26.7782426778243, Blast_Score=75, Evalue=2e-14,
Organism=Escherichia coli, GI1789808, Length=208, Percent_Identity=27.8846153846154, Blast_Score=73, Evalue=6e-14,
Organism=Escherichia coli, GI1789403, Length=202, Percent_Identity=25.7425742574257, Blast_Score=70, Evalue=5e-13,
Organism=Escherichia coli, GI87082128, Length=241, Percent_Identity=25.7261410788382, Blast_Score=69, Evalue=7e-13,
Organism=Escherichia coli, GI1790551, Length=223, Percent_Identity=27.3542600896861, Blast_Score=69, Evalue=1e-12,
Organism=Escherichia coli, GI1787374, Length=223, Percent_Identity=23.3183856502242, Blast_Score=62, Evalue=7e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR003660
- InterPro:   IPR000014
- InterPro:   IPR013767
- InterPro:   IPR004358
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR009082 [H]

Pfam domain/function: PF00672 HAMP; PF02518 HATPase_c; PF00512 HisKA; PF00989 PAS [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 63007; Mature: 62876

Theoretical pI: Translated: 5.40; Mature: 5.40

Prosite motif: PS50885 HAMP ; PS50112 PAS ; PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
1.7 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
1.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MARSLKWRLISLFCLLIAASVGLLSIFLSNHLENSYLDNLQSRLVQEATLLSEIVPEHIS
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHC
EDPDSFDAYIKELGASLDIRLTVIDPGGQVLADSLQSPSDMENHSTRVEFIDALKNGLGT
CCCHHHHHHHHHHCCCCEEEEEEECCCCHHHHHHCCCCCCCHHHHHHHHHHHHHHHCCCC
SVHQSASLGYEMLYVAIPVKSGTEVLAVVRVALPVEEVYAAVGDVDRTILLSALISILAA
CHHHHHHCCEEEEEEEEECCCCHHHHHHHHHHCCHHHHHHHHCCCHHHHHHHHHHHHHHH
GLLAVWVAASLTRPIKELTAIARRIARGQMDAVQIEVSGKGEMEELAHAFRLMTERLRDS
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEECCCCCHHHHHHHHHHHHHHHHHH
INAVSSERDRLSAVLERMGDGIFLLDCEGTISLLNPAAERIFKLEAEHVIGHSFVEAIRD
HHHHHHHHHHHHHHHHHHCCCEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
HEIHSIFEHSKSSGKQEMGFVELASGRRFLGIIATPLVSQSGYLVLVQDLSELRRLEKVR
HHHHHHHHHHHCCCCHHCCCEEECCCCEEEHHHHHHHHCCCCCEEEHHHHHHHHHHHHHH
RDFVANISHELRTPISSLKLLTETLQEGAASDAAVAAGFIEKIHLEVDKLAQLVTELSDL
HHHHHHHHHHHHCHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
SAIESGQAVLNLQPGDISTAIKLAAARLSPQAERAGISLGVELPETLPQVKLDENRIEQV
HHHCCCCEEEEECCCCHHHHHHHHHHHCCCHHHHCCCEECCCCHHHCCCCCCCHHHHHHH
LVNLVHNAIKFTPKGGRIKIGARTQGQILVVYVSDSGIGIPEDDLTRVFERFYKVDKARS
HHHHHHHHHEECCCCCEEEECCCCCCCEEEEEECCCCCCCCHHHHHHHHHHHHHHHHCCC
GGGTGLGLAISKHIVQAHGGNIWAESRYGKGATFSFSLPLG
CCCCCHHHHHHHHHHHHCCCCEEECCCCCCCCEEEEECCCC
>Mature Secondary Structure 
ARSLKWRLISLFCLLIAASVGLLSIFLSNHLENSYLDNLQSRLVQEATLLSEIVPEHIS
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHC
EDPDSFDAYIKELGASLDIRLTVIDPGGQVLADSLQSPSDMENHSTRVEFIDALKNGLGT
CCCHHHHHHHHHHCCCCEEEEEEECCCCHHHHHHCCCCCCCHHHHHHHHHHHHHHHCCCC
SVHQSASLGYEMLYVAIPVKSGTEVLAVVRVALPVEEVYAAVGDVDRTILLSALISILAA
CHHHHHHCCEEEEEEEEECCCCHHHHHHHHHHCCHHHHHHHHCCCHHHHHHHHHHHHHHH
GLLAVWVAASLTRPIKELTAIARRIARGQMDAVQIEVSGKGEMEELAHAFRLMTERLRDS
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEECCCCCHHHHHHHHHHHHHHHHHH
INAVSSERDRLSAVLERMGDGIFLLDCEGTISLLNPAAERIFKLEAEHVIGHSFVEAIRD
HHHHHHHHHHHHHHHHHHCCCEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
HEIHSIFEHSKSSGKQEMGFVELASGRRFLGIIATPLVSQSGYLVLVQDLSELRRLEKVR
HHHHHHHHHHHCCCCHHCCCEEECCCCEEEHHHHHHHHCCCCCEEEHHHHHHHHHHHHHH
RDFVANISHELRTPISSLKLLTETLQEGAASDAAVAAGFIEKIHLEVDKLAQLVTELSDL
HHHHHHHHHHHHCHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
SAIESGQAVLNLQPGDISTAIKLAAARLSPQAERAGISLGVELPETLPQVKLDENRIEQV
HHHCCCCEEEEECCCCHHHHHHHHHHHCCCHHHHCCCEECCCCHHHCCCCCCCHHHHHHH
LVNLVHNAIKFTPKGGRIKIGARTQGQILVVYVSDSGIGIPEDDLTRVFERFYKVDKARS
HHHHHHHHHEECCCCCEEEECCCCCCCEEEEEECCCCCCCCHHHHHHHHHHHHHHHHCCC
GGGTGLGLAISKHIVQAHGGNIWAESRYGKGATFSFSLPLG
CCCCCHHHHHHHHHHHHCCCCEEECCCCCCCCEEEEECCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 7934829; 9384377; 8631715 [H]