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The map label for this gene is gmhA [H]

Identifier: 57235013

GI number: 57235013

Start: 199374

End: 200024

Strand: Direct

Name: gmhA [H]

Synonym: DET0207

Alternate gene names: 57235013

Gene position: 199374-200024 (Clockwise)

Preceding gene: 57235014

Following gene: 57235012

Centisome position: 13.57

GC content: 53.61

Gene sequence:

>651_bases
ATGATTATCAGCAAGCCGGATGTTGCCAACGGCAAAGGGCACAAGCCCGAATTACCGGAAACCAGTCTTGTAAGCGATAT
GGACTGTTTGTTCCGTGAGTACCTGGGGGGTCTAAGCCATTGTCTGGAAGAGCTGGCTGCCCAGGATATCAGCGGGGTAG
CGGAGCTGATTTATCAAGCTTATAGCCGCCGCCGCCAGATATTTATTGTGGGCAACGGGGGAAGCGCCTTTACTGCTTCG
CATATGGCCCGTGATTTGCGGATAGGCACAGCCCTCCGGGGTAAACCCCGCCTGCGCACCTGCAGCCTGGCTGACAATGT
GGCTTTTATCACTTCTCTGGCTAATGATGTTAATTATGAGTCTATCTTTACGGAGCAGCTTATCGGCCAGATAGAGCCGG
GAGACGTGCTGATAGCTATCAGCTGTTCGGGCAATTCGGCCAATGTGGTACGGGCGGTGGAATACGCCAATGAATGCGGT
GCCTCTACGGTGGGGCTGACCGGTTTCGGCGGGGGAAAGCTGCTTGAGCTTTGTGACCGCTGCATAGTCCTTTCCAGCTG
TGATTACGGGCAGGTGGAAGATGTGCACCTGAGCCTTGGGCATATCTTTTCCTGTATGGTAAAGGCCCGCATAGAAAAAG
AAACTGTCTAG

Upstream 100 bases:

>100_bases
GGCGCTTTCAGATTTGCCGCAGGTGGATTTTGAGTTTGAACCTGAGGGCAGCAAGATAATTTATGTTTTGTAAATTTCAG
AATGCAAATGGAGGTAAATT

Downstream 100 bases:

>100_bases
TTCGGGGATTAGCCTTGGAAAATATAATGAGCCTTTCGGTAGTAATTTGTACCCGAAACAGTGCTTCTACTATAAAAGAC
TGTCTGGATTCGCTTATGCC

Product: phosphoheptose isomerase

Products: NA

Alternate protein names: Sedoheptulose 7-phosphate isomerase [H]

Number of amino acids: Translated: 216; Mature: 216

Protein sequence:

>216_residues
MIISKPDVANGKGHKPELPETSLVSDMDCLFREYLGGLSHCLEELAAQDISGVAELIYQAYSRRRQIFIVGNGGSAFTAS
HMARDLRIGTALRGKPRLRTCSLADNVAFITSLANDVNYESIFTEQLIGQIEPGDVLIAISCSGNSANVVRAVEYANECG
ASTVGLTGFGGGKLLELCDRCIVLSSCDYGQVEDVHLSLGHIFSCMVKARIEKETV

Sequences:

>Translated_216_residues
MIISKPDVANGKGHKPELPETSLVSDMDCLFREYLGGLSHCLEELAAQDISGVAELIYQAYSRRRQIFIVGNGGSAFTAS
HMARDLRIGTALRGKPRLRTCSLADNVAFITSLANDVNYESIFTEQLIGQIEPGDVLIAISCSGNSANVVRAVEYANECG
ASTVGLTGFGGGKLLELCDRCIVLSSCDYGQVEDVHLSLGHIFSCMVKARIEKETV
>Mature_216_residues
MIISKPDVANGKGHKPELPETSLVSDMDCLFREYLGGLSHCLEELAAQDISGVAELIYQAYSRRRQIFIVGNGGSAFTAS
HMARDLRIGTALRGKPRLRTCSLADNVAFITSLANDVNYESIFTEQLIGQIEPGDVLIAISCSGNSANVVRAVEYANECG
ASTVGLTGFGGGKLLELCDRCIVLSSCDYGQVEDVHLSLGHIFSCMVKARIEKETV

Specific function: Catalyzes the isomerization of sedoheptulose 7-phosphate in D-glycero-D-manno-heptose 7-phosphate [H]

COG id: COG0279

COG function: function code G; Phosphoheptose isomerase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 SIS domain [H]

Homologues:

Organism=Escherichia coli, GI1786416, Length=168, Percent_Identity=32.7380952380952, Blast_Score=78, Evalue=4e-16,
Organism=Escherichia coli, GI1789539, Length=151, Percent_Identity=32.4503311258278, Blast_Score=70, Evalue=9e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004515
- InterPro:   IPR020620
- InterPro:   IPR001347 [H]

Pfam domain/function: PF01380 SIS [H]

EC number: =5.3.1.28 [H]

Molecular weight: Translated: 23236; Mature: 23236

Theoretical pI: Translated: 5.07; Mature: 5.07

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

4.2 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
6.0 %Cys+Met (Translated Protein)
4.2 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
6.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIISKPDVANGKGHKPELPETSLVSDMDCLFREYLGGLSHCLEELAAQDISGVAELIYQA
CCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
YSRRRQIFIVGNGGSAFTASHMARDLRIGTALRGKPRLRTCSLADNVAFITSLANDVNYE
HHCCCEEEEEECCCCHHHHHHHHHHHHHCCCCCCCCCCEEECHHHHHHHHHHHHCCCCHH
SIFTEQLIGQIEPGDVLIAISCSGNSANVVRAVEYANECGASTVGLTGFGGGKLLELCDR
HHHHHHHHCCCCCCCEEEEEEECCCCCHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHH
CIVLSSCDYGQVEDVHLSLGHIFSCMVKARIEKETV
HHEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MIISKPDVANGKGHKPELPETSLVSDMDCLFREYLGGLSHCLEELAAQDISGVAELIYQA
CCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
YSRRRQIFIVGNGGSAFTASHMARDLRIGTALRGKPRLRTCSLADNVAFITSLANDVNYE
HHCCCEEEEEECCCCHHHHHHHHHHHHHCCCCCCCCCCEEECHHHHHHHHHHHHCCCCHH
SIFTEQLIGQIEPGDVLIAISCSGNSANVVRAVEYANECGASTVGLTGFGGGKLLELCDR
HHHHHHHHCCCCCCCEEEEEEECCCCCHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHH
CIVLSSCDYGQVEDVHLSLGHIFSCMVKARIEKETV
HHEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA