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The map label for this gene is cobD-1 [H]

Identifier: 57234943

GI number: 57234943

Start: 236546

End: 237502

Strand: Direct

Name: cobD-1 [H]

Synonym: DET0246

Alternate gene names: 57234943

Gene position: 236546-237502 (Clockwise)

Preceding gene: 57234944

Following gene: 57234942

Centisome position: 16.09

GC content: 54.75

Gene sequence:

>957_bases
ATGAACGAATATATCCTGATACTTATTCTGGCTGTCCTTTGGGATTTGGCTCTGGCTGAGCCTCCGGCGGCTATCCACCT
GACTGTCTGGATAGGGCGGGTGATTTCGCTGGTGGAGAAGGCAGGGCTTAAGATACGCAGTCGCGCCCTGCAGTATATCT
TCGGCATGGCGGCCTCTTTGTTCCTGATAGCTTTATTCGGCTGGCTGACTTATCTGCTGCTTGATTATCTGGGCGGCCTA
AGCTTTGCCTTATACCTGATAGCCGCCTTTTTAATCCTGAAGACCACGTTCTGTTTACGCTTTAACGCCCGCATGTCTTT
ACTGGTGGAGAAATACCTGAAAGGCGGGGACTACCGGATAGAGAGTGCCGCCCCGGAAATCCGCTATCTTCTGACAACGG
TTGAACGTGACAAGGAGGACGGATTTGCTCCGCCCATGATATCCTCCACCATCCGTTCGCTGGCGGAAAACGCTTCGGAT
TTTCTGGTAGCCCCTCTGTTCTATTTTCTGATTCTGGGTGTGCCGGGGGCGGTGGCCTACCGGGTTTGCAACACCCTGGA
CGGTATGCTGGGACACCGCGGTGAGTACGAATACCTGGGTAAGTTTGCCGCCTGCCTGGATGATATCATTAACTATCTGC
CGTCCAGACTTACCGGGCTGATGTTTATACTGGCGGCTTTTGTTTCGGGGATGGATGGCCAAAACGCCTGGAGGATTGCC
CTCAGGGACCAGTCCAAAACCGAAAGCCCCAATGCCGGCTGGCCGATGGCATCTGTTGCCGGAGCACTGGGGGTAAGGCT
GGAGCGGGCTGGCCACTATGCGCTGGGGGATGCGGCAAAACCCCTCAGCCCCGGTCACATTGGTCAGGCCGTAAGGCTGT
TCGGGGTGATGTCCGCTATCAGCATTGCCATCAGTACGGGCATACTGCTGGCGGTATATTTAATAAGCTTGAACTGA

Upstream 100 bases:

>100_bases
CAAAAGCAGACCTGGTGGCTGAATTTCGCAAACTGAAGCACCCGTATGACCGGGGTATTTTAGCCCGGGCGGGTATAGAC
TATTAGGTGAATAAAACACA

Downstream 100 bases:

>100_bases
TGGGAGGTGGCTTTTATGGCCAGAGAAATGACACATTGTTACGTTAAAATACCGGTTAAACCGCTGGATGATACTGCTAT
GGAAAAACTGCGCCAGCTGG

Product: cobalamin biosynthesis protein CobD

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 318; Mature: 318

Protein sequence:

>318_residues
MNEYILILILAVLWDLALAEPPAAIHLTVWIGRVISLVEKAGLKIRSRALQYIFGMAASLFLIALFGWLTYLLLDYLGGL
SFALYLIAAFLILKTTFCLRFNARMSLLVEKYLKGGDYRIESAAPEIRYLLTTVERDKEDGFAPPMISSTIRSLAENASD
FLVAPLFYFLILGVPGAVAYRVCNTLDGMLGHRGEYEYLGKFAACLDDIINYLPSRLTGLMFILAAFVSGMDGQNAWRIA
LRDQSKTESPNAGWPMASVAGALGVRLERAGHYALGDAAKPLSPGHIGQAVRLFGVMSAISIAISTGILLAVYLISLN

Sequences:

>Translated_318_residues
MNEYILILILAVLWDLALAEPPAAIHLTVWIGRVISLVEKAGLKIRSRALQYIFGMAASLFLIALFGWLTYLLLDYLGGL
SFALYLIAAFLILKTTFCLRFNARMSLLVEKYLKGGDYRIESAAPEIRYLLTTVERDKEDGFAPPMISSTIRSLAENASD
FLVAPLFYFLILGVPGAVAYRVCNTLDGMLGHRGEYEYLGKFAACLDDIINYLPSRLTGLMFILAAFVSGMDGQNAWRIA
LRDQSKTESPNAGWPMASVAGALGVRLERAGHYALGDAAKPLSPGHIGQAVRLFGVMSAISIAISTGILLAVYLISLN
>Mature_318_residues
MNEYILILILAVLWDLALAEPPAAIHLTVWIGRVISLVEKAGLKIRSRALQYIFGMAASLFLIALFGWLTYLLLDYLGGL
SFALYLIAAFLILKTTFCLRFNARMSLLVEKYLKGGDYRIESAAPEIRYLLTTVERDKEDGFAPPMISSTIRSLAENASD
FLVAPLFYFLILGVPGAVAYRVCNTLDGMLGHRGEYEYLGKFAACLDDIINYLPSRLTGLMFILAAFVSGMDGQNAWRIA
LRDQSKTESPNAGWPMASVAGALGVRLERAGHYALGDAAKPLSPGHIGQAVRLFGVMSAISIAISTGILLAVYLISLN

Specific function: Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group [H]

COG id: COG1270

COG function: function code H; Cobalamin biosynthesis protein CobD/CbiB

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the CobD/CbiB family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004485 [H]

Pfam domain/function: PF03186 CobD_Cbib [H]

EC number: NA

Molecular weight: Translated: 34752; Mature: 34752

Theoretical pI: Translated: 8.03; Mature: 8.03

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNEYILILILAVLWDLALAEPPAAIHLTVWIGRVISLVEKAGLKIRSRALQYIFGMAASL
CCCHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHH
FLIALFGWLTYLLLDYLGGLSFALYLIAAFLILKTTFCLRFNARMSLLVEKYLKGGDYRI
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEE
ESAAPEIRYLLTTVERDKEDGFAPPMISSTIRSLAENASDFLVAPLFYFLILGVPGAVAY
CCCCHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHCHHHHHHHHHHHHHHHCCCHHHHH
RVCNTLDGMLGHRGEYEYLGKFAACLDDIINYLPSRLTGLMFILAAFVSGMDGQNAWRIA
HHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEE
LRDQSKTESPNAGWPMASVAGALGVRLERAGHYALGDAAKPLSPGHIGQAVRLFGVMSAI
ECCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHH
SIAISTGILLAVYLISLN
HHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MNEYILILILAVLWDLALAEPPAAIHLTVWIGRVISLVEKAGLKIRSRALQYIFGMAASL
CCCHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHH
FLIALFGWLTYLLLDYLGGLSFALYLIAAFLILKTTFCLRFNARMSLLVEKYLKGGDYRI
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEE
ESAAPEIRYLLTTVERDKEDGFAPPMISSTIRSLAENASDFLVAPLFYFLILGVPGAVAY
CCCCHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHCHHHHHHHHHHHHHHHCCCHHHHH
RVCNTLDGMLGHRGEYEYLGKFAACLDDIINYLPSRLTGLMFILAAFVSGMDGQNAWRIA
HHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEE
LRDQSKTESPNAGWPMASVAGALGVRLERAGHYALGDAAKPLSPGHIGQAVRLFGVMSAI
ECCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHH
SIAISTGILLAVYLISLN
HHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA