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The map label for this gene is nrdR

Identifier: 57234896

GI number: 57234896

Start: 328749

End: 329276

Strand: Direct

Name: nrdR

Synonym: DET0344

Alternate gene names: 57234896

Gene position: 328749-329276 (Clockwise)

Preceding gene: 57234897

Following gene: 57234895

Centisome position: 22.37

GC content: 49.62

Gene sequence:

>528_bases
GTGAATTGTCCTTATTGCAGCCATCCTGATACCAAGGTTATAGACTCAAGAGATGTTGATGACGGGGTACGACGAAGACG
CGAATGTGTAGTTTGCGGGCAGCGCTTTACCACCTATGAGCGGTTTCAGCCGGCCGGTCTCTTTGTAGTGAAAAAAGACC
AGCGGCGTGAGGAGTTTAATAAAGAAAAATTGCTGAGCGGTCTCAGGCGTGCCTGTGAAAAACGCCCTTTGCCGGCCGGA
GCGGTGGATAAGATAGCCGGAGATATAGAGGCCGAACTTTACAATATGGGTAAGGCTGAAATACCCAGTACCCTTTTGGG
GGATATGGTTATGGAAAAGCTTAAGGCACTGGATAATATTGCCTATGTGCGCTTTGCCAGTGTCTACCGCGAGTTTACCG
ATATTACCCAGCTTAAAAAAGTGGTGGACAATCTGGTAAGCGGGCAGGATGAGGGCATACATAAAGGGCAGCTGAGCCTG
CTGCCTGAAGACAGGGTCTCCCCCAAGACCAGATATCAGAGGAGATGA

Upstream 100 bases:

>100_bases
CCTGTTTCTTTGTAAAAAATAGGACTATTTACGTATTGACTACCACTATCCCTTGTGTTAATCTATCTGCGCAACACAAT
ATACAGTGTTGGAGGGCGTA

Downstream 100 bases:

>100_bases
CATGGTAAATCACATAAGCGGTAAGAAACCAACTCCGGTTAATCGTAACCGCGTGGCCAGGGCTATGTTTGCAGCCGCGG
CCTCAATGGGTATTTCCGAC

Product: transcriptional regulator NrdR

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 175; Mature: 175

Protein sequence:

>175_residues
MNCPYCSHPDTKVIDSRDVDDGVRRRRECVVCGQRFTTYERFQPAGLFVVKKDQRREEFNKEKLLSGLRRACEKRPLPAG
AVDKIAGDIEAELYNMGKAEIPSTLLGDMVMEKLKALDNIAYVRFASVYREFTDITQLKKVVDNLVSGQDEGIHKGQLSL
LPEDRVSPKTRYQRR

Sequences:

>Translated_175_residues
MNCPYCSHPDTKVIDSRDVDDGVRRRRECVVCGQRFTTYERFQPAGLFVVKKDQRREEFNKEKLLSGLRRACEKRPLPAG
AVDKIAGDIEAELYNMGKAEIPSTLLGDMVMEKLKALDNIAYVRFASVYREFTDITQLKKVVDNLVSGQDEGIHKGQLSL
LPEDRVSPKTRYQRR
>Mature_175_residues
MNCPYCSHPDTKVIDSRDVDDGVRRRRECVVCGQRFTTYERFQPAGLFVVKKDQRREEFNKEKLLSGLRRACEKRPLPAG
AVDKIAGDIEAELYNMGKAEIPSTLLGDMVMEKLKALDNIAYVRFASVYREFTDITQLKKVVDNLVSGQDEGIHKGQLSL
LPEDRVSPKTRYQRR

Specific function: Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes

COG id: COG1327

COG function: function code K; Predicted transcriptional regulator, consists of a Zn-ribbon and ATP-cone domains

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ATP-cone domain

Homologues:

Organism=Escherichia coli, GI1786615, Length=147, Percent_Identity=49.6598639455782, Blast_Score=144, Evalue=3e-36,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NRDR_DEHE1 (Q3Z9K8)

Other databases:

- EMBL:   CP000027
- RefSeq:   YP_181091.1
- STRING:   Q3Z9K8
- GeneID:   3230365
- GenomeReviews:   CP000027_GR
- KEGG:   det:DET0344
- NMPDR:   fig|243164.3.peg.355
- TIGR:   DET0344
- eggNOG:   COG1327
- HOGENOM:   HBG351755
- OMA:   FASVYRD
- PhylomeDB:   Q3Z9K8
- ProtClustDB:   PRK00464
- BioCyc:   DETH243164:DET_0344-MONOMER
- GO:   GO:0006350
- HAMAP:   MF_00440
- InterPro:   IPR005144
- InterPro:   IPR003796
- TIGRFAMs:   TIGR00244

Pfam domain/function: PF03477 ATP-cone

EC number: NA

Molecular weight: Translated: 20054; Mature: 20054

Theoretical pI: Translated: 8.96; Mature: 8.96

Prosite motif: PS51161 ATP_CONE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.9 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
5.1 %Cys+Met (Translated Protein)
2.9 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
5.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNCPYCSHPDTKVIDSRDVDDGVRRRRECVVCGQRFTTYERFQPAGLFVVKKDQRREEFN
CCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHCCHHHHHHHCCCCCEEEECCHHHHHHCC
KEKLLSGLRRACEKRPLPAGAVDKIAGDIEAELYNMGKAEIPSTLLGDMVMEKLKALDNI
HHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHCCCHHCCHHHHHHHHHHHHHHHHHH
AYVRFASVYREFTDITQLKKVVDNLVSGQDEGIHKGQLSLLPEDRVSPKTRYQRR
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCHHHCCCC
>Mature Secondary Structure
MNCPYCSHPDTKVIDSRDVDDGVRRRRECVVCGQRFTTYERFQPAGLFVVKKDQRREEFN
CCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHCCHHHHHHHCCCCCEEEECCHHHHHHCC
KEKLLSGLRRACEKRPLPAGAVDKIAGDIEAELYNMGKAEIPSTLLGDMVMEKLKALDNI
HHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHCCCHHCCHHHHHHHHHHHHHHHHHH
AYVRFASVYREFTDITQLKKVVDNLVSGQDEGIHKGQLSLLPEDRVSPKTRYQRR
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA