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The map label for this gene is infA

Identifier: 57234756

GI number: 57234756

Start: 457298

End: 457519

Strand: Direct

Name: infA

Synonym: DET0497

Alternate gene names: 57234756

Gene position: 457298-457519 (Clockwise)

Preceding gene: 57234757

Following gene: 57234755

Centisome position: 31.11

GC content: 49.55

Gene sequence:

>222_bases
ATGCCTAAAAAAGATGCAATAGAAGTTGAAGCGACAGTGCTGGAGGCTTTGCCCAGTGCCGCTTTTCGTGTTCAGCTTTC
AAACGGGCATGAAGTCCTGGCGCATATTTCGGGCAAGATGCGGGTACATTACATAAGGATTTTGCCCGGAGACAGAGTAC
TGGTGGAGTTATCTCCCTATGACTTGACCCGCGGCCGGGTTACATACCGATTCAAGTCATAG

Upstream 100 bases:

>100_bases
TACTGCGGATGGCAGTTTGTCGGCTCATTTTGAACATACAGTTGCCATTACCGATGGTGAGCCGGAAATACTCACCGTGA
TAGAAGGATAGCGGGGATTT

Downstream 100 bases:

>100_bases
GTTTGGGAAGGATACAGGAGAACAGCAAATGAAGGTTAGAGCTTCGGTAAAGACAATGTGCGAAAAGTGCAAAATAGTGA
AACGTAACGGGGTGGTTAGA

Product: translation initiation factor IF-1

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 73; Mature: 72

Protein sequence:

>73_residues
MPKKDAIEVEATVLEALPSAAFRVQLSNGHEVLAHISGKMRVHYIRILPGDRVLVELSPYDLTRGRVTYRFKS

Sequences:

>Translated_73_residues
MPKKDAIEVEATVLEALPSAAFRVQLSNGHEVLAHISGKMRVHYIRILPGDRVLVELSPYDLTRGRVTYRFKS
>Mature_72_residues
PKKDAIEVEATVLEALPSAAFRVQLSNGHEVLAHISGKMRVHYIRILPGDRVLVELSPYDLTRGRVTYRFKS

Specific function: No specific function has so far been attributed to this initiation factor; however, it seems to stimulate more or less all the activities of the other two initiation factors, IF-2 and IF-3

COG id: COG0361

COG function: function code J; Translation initiation factor 1 (IF-1)

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 S1-like domain

Homologues:

Organism=Escherichia coli, GI1787110, Length=70, Percent_Identity=64.2857142857143, Blast_Score=102, Evalue=6e-24,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): IF1_DEHE1 (Q3Z958)

Other databases:

- EMBL:   CP000027
- RefSeq:   YP_181241.1
- ProteinModelPortal:   Q3Z958
- SMR:   Q3Z958
- STRING:   Q3Z958
- GeneID:   3230225
- GenomeReviews:   CP000027_GR
- KEGG:   det:DET0497
- TIGR:   DET0497
- eggNOG:   COG0361
- HOGENOM:   HBG286099
- OMA:   KMRMHFI
- PhylomeDB:   Q3Z958
- ProtClustDB:   PRK00276
- BioCyc:   DETH243164:DET_0497-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_00075
- InterPro:   IPR012340
- InterPro:   IPR016027
- InterPro:   IPR022967
- InterPro:   IPR006196
- InterPro:   IPR004368
- Gene3D:   G3DSA:2.40.50.140
- SMART:   SM00316
- TIGRFAMs:   TIGR00008

Pfam domain/function: PF01176 eIF-1a; SSF50249 Nucleic_acid_OB

EC number: NA

Molecular weight: Translated: 8248; Mature: 8117

Theoretical pI: Translated: 10.05; Mature: 10.05

Prosite motif: PS50832 S1_IF1_TYPE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
1.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPKKDAIEVEATVLEALPSAAFRVQLSNGHEVLAHISGKMRVHYIRILPGDRVLVELSPY
CCCCCCEEEHHHHHHHCCCEEEEEEECCCCEEEEEECCCEEEEEEEECCCCEEEEEECCC
DLTRGRVTYRFKS
CCCCCEEEEEECC
>Mature Secondary Structure 
PKKDAIEVEATVLEALPSAAFRVQLSNGHEVLAHISGKMRVHYIRILPGDRVLVELSPY
CCCCCEEEHHHHHHHCCCEEEEEEECCCCEEEEEECCCEEEEEEEECCCCEEEEEECCC
DLTRGRVTYRFKS
CCCCCEEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA