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The map label for this gene is rpoC

Identifier: 57234591

GI number: 57234591

Start: 558413

End: 562300

Strand: Direct

Name: rpoC

Synonym: DET0604

Alternate gene names: 57234591

Gene position: 558413-562300 (Clockwise)

Preceding gene: 57234592

Following gene: 57234581

Centisome position: 37.99

GC content: 52.34

Gene sequence:

>3888_bases
ATGAACGAAGTTAATGATTTTGATGCAATACGGATTTCACTGGCTTCCCCTGACCAGATAAGAAGCTGGTCTTATGGTGA
GGTTACCAAACCTGAAACCATAAACTATCGTACGTTAAAGCCGGAGCGGGACGGTCTGTTCTGTGAGCGTATCTTCGGCC
CTATAAAGGACTTTGAGTGTGCCTGCGGCAAATACAAACGTATCCGCTACAAGGGCATTATATGTGACAAGTGCGGCGTG
GAAATTGCTCGTGCCAAGGTACGGCGTGAACGGATGGGGCATATTGAACTGGCCTGTCCGGTAGGCCATATCTGGTTTAC
CCGCGGTATTCCCAGCCGGGTAGGCCTGCTGCTTAATTTGTCCACCCGCAGCCTTGAAAGGATAATTTATTATTCCCATT
TCATTATAACCGGGGTAAATGACGAAGCCCGTGAAAAGGCCATTAAAGATTTGGAGGTTATTTCCTCCCAGCGGGTAGCT
GATAAGGGCAGCGAGGTAGATACCAGGGTTGCCCAGATGGAAGCCGAAGATGCCACTGTTGAAGCCATAAATCAGGTTCG
CCGTGATTTTTCAACTGAACGTGAGCAGATGGAAGAAGATATCCAGCTGCTTATAGACCAGCTGAAAGACCTCCAAATAG
GCAATTTGCTGACCGAAAACCAGTATTACGAGCTGAAACAGCGTTTCAGCAATGTTTTTGAGGCCTCCATGGGTGCCGAA
GCTCTGCTTAAGCTGCTTTCTTATATAGATATGGATAAGGAGCGGAGCAAACTTATTCAGGAAACCCGCTCCACTTCCGG
CCAGCGCCGCAAAAAGGCTGGCAAACAGCTTCAGCTGGTAGAGGCTTTCCGCCGCTCCAGCAACAAGCCTGAGTGGATGA
TTATGACGGTTCTGCCGGTACTGCCGCCTGACCTGCGTCCTATGGTTCAGCTTGACGGCGGCCGTTTTGCCACCAGTGAC
TTAAATGACCTTTACCGCCGGGTTATCAACCGGAACAACCGTCTCCAGCACCTGATGGAAATCGGGGCGCCGGAGATTAT
TATCCGCAACGAAAAGCGTATGCTTCAGGAAGCGGTGGATTCACTTATTGATAACGGACGCCGCGGCAAGAGCGTGGCTG
TAAATGGTGACCACAAAGCCAAGTCCCTTTCTGACCTGCTTCGCGGCAAACAGGGACGCTTCCGCCAGAACCTGCTGGGT
AAACGGGTTGACTATTCAGGCCGTTCGGTTATTGTGGTAGGCCCTTCACTCAAACTTTCACAGTGCGGTCTGCCCCGCCG
TATGGCACTTGAACTCTTTAAGCCCTTTGTCATGCACCGCTTGGTACGGGACGGCTTAGCCCCCAATATCAAGAGCGCCC
GCCGTCTGGTAGAGCGCGCCCGCCCGGAGGTTTACGATATTCTGGAAGAGGTGGTCAAGGAGAGGCCGGTTATGCTTAAC
CGCGCTCCCACTCTGCACCGCCTTAGTATCCAGGCCTTTGAGCCGGTGCTTATTGACGGCAGTGCCCTCAGGCTTCACCC
GCTGGTCTGTTCAGCCTTTAACGCTGACTTTGACGGTGACCAGATGGCTGTCCACGTGCCCCTTTCCAAAGCGGCCGTGA
AGGAAGCCCGTGAAACCATGCTGTCCATTCATAATATGATGCTTCCCTCCAGCGGTGAGCCGGTGGTATCCCCCAGCCTT
GATATGGTCTTCGGGTGTTATTACCTGACTACTACCCGGCCGGGTGCTAAGGGTGAAGGCAAGATATTCAGTGACTTTGA
AGAAGCCAAGCACTATTACGAAATGGGTATTATTGACCTCAGGGCTATTATCAAAGTCCGTGACGGCAAGGGTAATATGC
TGGAAACCACTACCGGGCGGATTATATTTAATGATGTCCTGCCCAAGGAAGTAGAGTTCCAGAATATGGATATACCCAAA
TCCGCCATCAAAAAGATAATCGGCCGCTGTTACAAGATTCTTTCCAGCCAGGATATGGCCGTCATGCTGGACAAGATAAA
ACAGCTTGGCTTCAAATACGCCACCAGCTCAGGCATTTCCATTGCCATGAGTGATATTTCGGTGCCGCGTGAAAAGGCCA
AGCTGGTAGCTGCCGCTGATGAGCGGACTGCCATTTCCGAAGGTCAGTTTGCCCGCGGTCTTATCACCGAAGACGAACGC
TACAACAGCATCATTGAAACCTGGATGGAAACTACTGACCGCATTACAGATGCTATTCAGGCCGGTTTTGACAAACAGGG
TTCCGTGTACATGATGGCTAACTCCGGCGCTAAGGGTAATATTTCCCAGATACGCCAGATGGCCGGTTTACGCGGCCTTA
TGACTAACCCGTCCGGCCGTATTATTGACTTCCCCATCAAGTCTTCCCTGCGTGAAGGCCTGACTACTCTGGAATACTTT
ATATCTACTCACGGTGCCCGCAAGGGTCTGGCTGACACCGCTTTACGTACGTCCGGTTCAGGTTACCTGACCCGCCGCCT
TATAGACGTAACCCAGGATGTTATTATCCTTCAGGAAGACTGCGGCACTTCAAACGGCACCTGGATAGTAGAACCCAAAG
AAAAGGGTATGCTGCCCCCGCTGGTTGACCGTGTACTCGGCCGCTGGGCAGCTCACAATGTGGTTCACCCCCAGACCGGC
GAAATTATCGTGGGTAACAATGAAGAGATTGACGAAGCTAAGGCTAAGGCTATCGGCGAAGCCGGTATCACCGAAGTCTT
TGTCCGCTCTCCGCTTACCTGCGAAGCTACTCACGGCATGTGCCGCCGCTGTTACGGGCGTGACCTTGGCCGTGTCCGTC
TGGTAGACATGAATACCGCCGTAGGTATCATTGCCGCCCAGAGTATCGGTGAGCCCGGTACCCAGCTGACACTCCGTACC
TTCCATACCGGCGGTGTGGTAGGCGTAGATATTACGACCGGTCTTCCCAGAGTTGAAGAACTCTTTGAGGCCCGTCCGCC
CAAGGTTCAGTCCATTATTTCTGAAATAGACGGTGAGGCCGAGGTTATTGAAAATGAAAACGGCCGCCATATCCGCATAT
TCTCTGATGAAGTATATCAGGACGAATATGAGCTGCCTTCCGGCTGGAAGACTCAGGTTCAAAGCGGACAGTGGGTGGAT
TCCGGCATGGTGCTGGCTTCGCCTGAAATGGAAGGCAAGTCCAAGGCGGTAGTTCAGAGTGACCAGAATGTGGTTGCCAG
AGTGGCCGGTGAAGTTTCAGTGGATGGCAGCCTTATCACCATCAAATACAGCGAAAGCGAAGAACGTGAATACGCTATAC
CTGCCGCCATGCAGATAAAGGTTAAAACCGGGGATAGTGTCCGTGCCGGTCAGCAGCTGACTGACGGCTCTATAAACCCG
CAGGATATTCTGTCCATTTTGGGCAGGGACGCTGTCCAGAAGTATCTGGTTGAAGAAGTCCAGAAGGTTTACTACTCTCA
GGGCGTACATATCAACGATAAACACATAGAGGTTATTGCCCGCCAGATGCTTATCAAGGTACGCATTGACTCCTCAGGTG
ATACTGACCTGGTTCCGGGTGAACTGGTAGACAAGTTCCGCTACGAGGATATCAACGCTAAGGTTCTGGCCGAAGGCGGC
GAACCGGCAACCGCCCATACCGTGCTTATGGGTATTACCCGTGCTTCACTCAGCACCGAAAGCTGGCTGGCGGCGGCCTC
CTTCCAGGAGACCACCCGTGTCCTTACTGATGCCGCCATTTACGGCAAGGTGGATAAGCTGTCCGGCCTTAAGGAAAATG
TTATCATAGGCAAGCTTATACCTGCCCAGTGCAAATCCTGCAAGGAAGCTACGGTTGAAAGAGCGGAACGGATAGCCGCT
GCCGCTGCCGCACCTGCGGTCAGCACTCTGCCGGAAAATTGCCTTTAG

Upstream 100 bases:

>100_bases
GCAGGCGCCGAGGATATTGAAGACTCCATGATGTCGGTAATTGATACTGACGACCAGGATTTGGCAATGTCATCAAATGA
TGAAGAGGTATCCGAAAACG

Downstream 100 bases:

>100_bases
GCTTAAATAAGCTTCGGTTGTTATAGTCTTGAAAAGAGGGGCGTAACGCCCCTCTTTTTATTATCCCGATATAGCCTGTT
TTATCAGTCCGCAAGGCATA

Product: DNA-directed RNA polymerase, beta' subunit

Products: NA

Alternate protein names: RNAP subunit beta'; RNA polymerase subunit beta'; Transcriptase subunit beta'

Number of amino acids: Translated: 1295; Mature: 1295

Protein sequence:

>1295_residues
MNEVNDFDAIRISLASPDQIRSWSYGEVTKPETINYRTLKPERDGLFCERIFGPIKDFECACGKYKRIRYKGIICDKCGV
EIARAKVRRERMGHIELACPVGHIWFTRGIPSRVGLLLNLSTRSLERIIYYSHFIITGVNDEAREKAIKDLEVISSQRVA
DKGSEVDTRVAQMEAEDATVEAINQVRRDFSTEREQMEEDIQLLIDQLKDLQIGNLLTENQYYELKQRFSNVFEASMGAE
ALLKLLSYIDMDKERSKLIQETRSTSGQRRKKAGKQLQLVEAFRRSSNKPEWMIMTVLPVLPPDLRPMVQLDGGRFATSD
LNDLYRRVINRNNRLQHLMEIGAPEIIIRNEKRMLQEAVDSLIDNGRRGKSVAVNGDHKAKSLSDLLRGKQGRFRQNLLG
KRVDYSGRSVIVVGPSLKLSQCGLPRRMALELFKPFVMHRLVRDGLAPNIKSARRLVERARPEVYDILEEVVKERPVMLN
RAPTLHRLSIQAFEPVLIDGSALRLHPLVCSAFNADFDGDQMAVHVPLSKAAVKEARETMLSIHNMMLPSSGEPVVSPSL
DMVFGCYYLTTTRPGAKGEGKIFSDFEEAKHYYEMGIIDLRAIIKVRDGKGNMLETTTGRIIFNDVLPKEVEFQNMDIPK
SAIKKIIGRCYKILSSQDMAVMLDKIKQLGFKYATSSGISIAMSDISVPREKAKLVAAADERTAISEGQFARGLITEDER
YNSIIETWMETTDRITDAIQAGFDKQGSVYMMANSGAKGNISQIRQMAGLRGLMTNPSGRIIDFPIKSSLREGLTTLEYF
ISTHGARKGLADTALRTSGSGYLTRRLIDVTQDVIILQEDCGTSNGTWIVEPKEKGMLPPLVDRVLGRWAAHNVVHPQTG
EIIVGNNEEIDEAKAKAIGEAGITEVFVRSPLTCEATHGMCRRCYGRDLGRVRLVDMNTAVGIIAAQSIGEPGTQLTLRT
FHTGGVVGVDITTGLPRVEELFEARPPKVQSIISEIDGEAEVIENENGRHIRIFSDEVYQDEYELPSGWKTQVQSGQWVD
SGMVLASPEMEGKSKAVVQSDQNVVARVAGEVSVDGSLITIKYSESEEREYAIPAAMQIKVKTGDSVRAGQQLTDGSINP
QDILSILGRDAVQKYLVEEVQKVYYSQGVHINDKHIEVIARQMLIKVRIDSSGDTDLVPGELVDKFRYEDINAKVLAEGG
EPATAHTVLMGITRASLSTESWLAAASFQETTRVLTDAAIYGKVDKLSGLKENVIIGKLIPAQCKSCKEATVERAERIAA
AAAAPAVSTLPENCL

Sequences:

>Translated_1295_residues
MNEVNDFDAIRISLASPDQIRSWSYGEVTKPETINYRTLKPERDGLFCERIFGPIKDFECACGKYKRIRYKGIICDKCGV
EIARAKVRRERMGHIELACPVGHIWFTRGIPSRVGLLLNLSTRSLERIIYYSHFIITGVNDEAREKAIKDLEVISSQRVA
DKGSEVDTRVAQMEAEDATVEAINQVRRDFSTEREQMEEDIQLLIDQLKDLQIGNLLTENQYYELKQRFSNVFEASMGAE
ALLKLLSYIDMDKERSKLIQETRSTSGQRRKKAGKQLQLVEAFRRSSNKPEWMIMTVLPVLPPDLRPMVQLDGGRFATSD
LNDLYRRVINRNNRLQHLMEIGAPEIIIRNEKRMLQEAVDSLIDNGRRGKSVAVNGDHKAKSLSDLLRGKQGRFRQNLLG
KRVDYSGRSVIVVGPSLKLSQCGLPRRMALELFKPFVMHRLVRDGLAPNIKSARRLVERARPEVYDILEEVVKERPVMLN
RAPTLHRLSIQAFEPVLIDGSALRLHPLVCSAFNADFDGDQMAVHVPLSKAAVKEARETMLSIHNMMLPSSGEPVVSPSL
DMVFGCYYLTTTRPGAKGEGKIFSDFEEAKHYYEMGIIDLRAIIKVRDGKGNMLETTTGRIIFNDVLPKEVEFQNMDIPK
SAIKKIIGRCYKILSSQDMAVMLDKIKQLGFKYATSSGISIAMSDISVPREKAKLVAAADERTAISEGQFARGLITEDER
YNSIIETWMETTDRITDAIQAGFDKQGSVYMMANSGAKGNISQIRQMAGLRGLMTNPSGRIIDFPIKSSLREGLTTLEYF
ISTHGARKGLADTALRTSGSGYLTRRLIDVTQDVIILQEDCGTSNGTWIVEPKEKGMLPPLVDRVLGRWAAHNVVHPQTG
EIIVGNNEEIDEAKAKAIGEAGITEVFVRSPLTCEATHGMCRRCYGRDLGRVRLVDMNTAVGIIAAQSIGEPGTQLTLRT
FHTGGVVGVDITTGLPRVEELFEARPPKVQSIISEIDGEAEVIENENGRHIRIFSDEVYQDEYELPSGWKTQVQSGQWVD
SGMVLASPEMEGKSKAVVQSDQNVVARVAGEVSVDGSLITIKYSESEEREYAIPAAMQIKVKTGDSVRAGQQLTDGSINP
QDILSILGRDAVQKYLVEEVQKVYYSQGVHINDKHIEVIARQMLIKVRIDSSGDTDLVPGELVDKFRYEDINAKVLAEGG
EPATAHTVLMGITRASLSTESWLAAASFQETTRVLTDAAIYGKVDKLSGLKENVIIGKLIPAQCKSCKEATVERAERIAA
AAAAPAVSTLPENCL
>Mature_1295_residues
MNEVNDFDAIRISLASPDQIRSWSYGEVTKPETINYRTLKPERDGLFCERIFGPIKDFECACGKYKRIRYKGIICDKCGV
EIARAKVRRERMGHIELACPVGHIWFTRGIPSRVGLLLNLSTRSLERIIYYSHFIITGVNDEAREKAIKDLEVISSQRVA
DKGSEVDTRVAQMEAEDATVEAINQVRRDFSTEREQMEEDIQLLIDQLKDLQIGNLLTENQYYELKQRFSNVFEASMGAE
ALLKLLSYIDMDKERSKLIQETRSTSGQRRKKAGKQLQLVEAFRRSSNKPEWMIMTVLPVLPPDLRPMVQLDGGRFATSD
LNDLYRRVINRNNRLQHLMEIGAPEIIIRNEKRMLQEAVDSLIDNGRRGKSVAVNGDHKAKSLSDLLRGKQGRFRQNLLG
KRVDYSGRSVIVVGPSLKLSQCGLPRRMALELFKPFVMHRLVRDGLAPNIKSARRLVERARPEVYDILEEVVKERPVMLN
RAPTLHRLSIQAFEPVLIDGSALRLHPLVCSAFNADFDGDQMAVHVPLSKAAVKEARETMLSIHNMMLPSSGEPVVSPSL
DMVFGCYYLTTTRPGAKGEGKIFSDFEEAKHYYEMGIIDLRAIIKVRDGKGNMLETTTGRIIFNDVLPKEVEFQNMDIPK
SAIKKIIGRCYKILSSQDMAVMLDKIKQLGFKYATSSGISIAMSDISVPREKAKLVAAADERTAISEGQFARGLITEDER
YNSIIETWMETTDRITDAIQAGFDKQGSVYMMANSGAKGNISQIRQMAGLRGLMTNPSGRIIDFPIKSSLREGLTTLEYF
ISTHGARKGLADTALRTSGSGYLTRRLIDVTQDVIILQEDCGTSNGTWIVEPKEKGMLPPLVDRVLGRWAAHNVVHPQTG
EIIVGNNEEIDEAKAKAIGEAGITEVFVRSPLTCEATHGMCRRCYGRDLGRVRLVDMNTAVGIIAAQSIGEPGTQLTLRT
FHTGGVVGVDITTGLPRVEELFEARPPKVQSIISEIDGEAEVIENENGRHIRIFSDEVYQDEYELPSGWKTQVQSGQWVD
SGMVLASPEMEGKSKAVVQSDQNVVARVAGEVSVDGSLITIKYSESEEREYAIPAAMQIKVKTGDSVRAGQQLTDGSINP
QDILSILGRDAVQKYLVEEVQKVYYSQGVHINDKHIEVIARQMLIKVRIDSSGDTDLVPGELVDKFRYEDINAKVLAEGG
EPATAHTVLMGITRASLSTESWLAAASFQETTRVLTDAAIYGKVDKLSGLKENVIIGKLIPAQCKSCKEATVERAERIAA
AAAAPAVSTLPENCL

Specific function: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates

COG id: COG0086

COG function: function code K; DNA-directed RNA polymerase, beta' subunit/160 kD subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the RNA polymerase beta' chain family

Homologues:

Organism=Homo sapiens, GI39725938, Length=1196, Percent_Identity=23.9966555183947, Blast_Score=220, Evalue=7e-57,
Organism=Homo sapiens, GI4505939, Length=510, Percent_Identity=28.2352941176471, Blast_Score=150, Evalue=6e-36,
Organism=Homo sapiens, GI103471997, Length=236, Percent_Identity=29.6610169491525, Blast_Score=90, Evalue=2e-17,
Organism=Escherichia coli, GI2367335, Length=1013, Percent_Identity=44.4225074037512, Blast_Score=832, Evalue=0.0,
Organism=Caenorhabditis elegans, GI25145495, Length=657, Percent_Identity=27.5494672754947, Blast_Score=174, Evalue=3e-43,
Organism=Caenorhabditis elegans, GI71987878, Length=341, Percent_Identity=31.6715542521994, Blast_Score=149, Evalue=7e-36,
Organism=Saccharomyces cerevisiae, GI6320061, Length=651, Percent_Identity=26.5745007680492, Blast_Score=171, Evalue=6e-43,
Organism=Saccharomyces cerevisiae, GI6324690, Length=671, Percent_Identity=25.1862891207154, Blast_Score=159, Evalue=3e-39,
Organism=Drosophila melanogaster, GI281360912, Length=851, Percent_Identity=26.0869565217391, Blast_Score=183, Evalue=6e-46,
Organism=Drosophila melanogaster, GI17530899, Length=292, Percent_Identity=34.2465753424658, Blast_Score=152, Evalue=1e-36,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): RPOC_DEHE1 (Q3Z8V3)

Other databases:

- EMBL:   CP000027
- RefSeq:   YP_181346.1
- ProteinModelPortal:   Q3Z8V3
- STRING:   Q3Z8V3
- GeneID:   3230059
- GenomeReviews:   CP000027_GR
- KEGG:   det:DET0604
- NMPDR:   fig|243164.3.peg.461
- TIGR:   DET0604
- eggNOG:   COG0086
- HOGENOM:   HBG621785
- OMA:   FEARVPK
- PhylomeDB:   Q3Z8V3
- ProtClustDB:   PRK00566
- BioCyc:   DETH243164:DET_0604-MONOMER
- HAMAP:   MF_01322
- InterPro:   IPR000722
- InterPro:   IPR006592
- InterPro:   IPR007080
- InterPro:   IPR007066
- InterPro:   IPR007083
- InterPro:   IPR007081
- InterPro:   IPR012754
- SMART:   SM00663
- TIGRFAMs:   TIGR02386

Pfam domain/function: PF04997 RNA_pol_Rpb1_1; PF00623 RNA_pol_Rpb1_2; PF04983 RNA_pol_Rpb1_3; PF05000 RNA_pol_Rpb1_4; PF04998 RNA_pol_Rpb1_5

EC number: =2.7.7.6

Molecular weight: Translated: 144101; Mature: 144101

Theoretical pI: Translated: 7.04; Mature: 7.04

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
4.2 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
4.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNEVNDFDAIRISLASPDQIRSWSYGEVTKPETINYRTLKPERDGLFCERIFGPIKDFEC
CCCCCCCCEEEEEECCCHHHCCCCCCCCCCCCCCCEEECCCCCCCCHHHHHHCCHHHHHH
ACGKYKRIRYKGIICDKCGVEIARAKVRRERMGHIELACPVGHIWFTRGIPSRVGLLLNL
HCCCCCEEEEEEEEECHHCHHHHHHHHHHHHCCCEEEECCCCCCCEECCCHHHHCEEEEC
STRSLERIIYYSHFIITGVNDEAREKAIKDLEVISSQRVADKGSEVDTRVAQMEAEDATV
CHHHHHHHHHHHEEEEECCCHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHCCCHHHH
EAINQVRRDFSTEREQMEEDIQLLIDQLKDLQIGNLLTENQYYELKQRFSNVFEASMGAE
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHCCCCCCCHHHHHHHHHHHHHHHHCCHH
ALLKLLSYIDMDKERSKLIQETRSTSGQRRKKAGKQLQLVEAFRRSSNKPEWMIMTVLPV
HHHHHHHHHCCCHHHHHHHHHHHHCCHHHHHHHCHHHHHHHHHHHCCCCCCEEEEEEECC
LPPDLRPMVQLDGGRFATSDLNDLYRRVINRNNRLQHLMEIGAPEIIIRNEKRMLQEAVD
CCCCCCCEEEECCCEEECCHHHHHHHHHHCCCHHHHHHHHCCCCEEEEECHHHHHHHHHH
SLIDNGRRGKSVAVNGDHKAKSLSDLLRGKQGRFRQNLLGKRVDYSGRSVIVVGPSLKLS
HHHHCCCCCCEEEECCCHHHHHHHHHHCCCCCHHHHHHHCCCCCCCCCEEEEECCCCCHH
QCGLPRRMALELFKPFVMHRLVRDGLAPNIKSARRLVERARPEVYDILEEVVKERPVMLN
HCCCCHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHCCHHHHHHHHHHHCCCEEEC
RAPTLHRLSIQAFEPVLIDGSALRLHPLVCSAFNADFDGDQMAVHVPLSKAAVKEARETM
CCCCCEEEEHHHCCCEEECCCCEEEHHHHHHHHCCCCCCCCEEEEECHHHHHHHHHHHHH
LSIHNMMLPSSGEPVVSPSLDMVFGCYYLTTTRPGAKGEGKIFSDFEEAKHYYEMGIIDL
HHHHHHHCCCCCCCCCCCCHHHHEEEEEEEECCCCCCCCCCCHHHHHHHHHHHHHHHHEE
RAIIKVRDGKGNMLETTTGRIIFNDVLPKEVEFQNMDIPKSAIKKIIGRCYKILSSQDMA
EEEEEEECCCCCEEEECCCCEEEECCCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCHH
VMLDKIKQLGFKYATSSGISIAMSDISVPREKAKLVAAADERTAISEGQFARGLITEDER
HHHHHHHHCCCHHCCCCCCEEEEECCCCCHHHHHEEEECCCHHHCCCCCHHCCCCCCCHH
YNSIIETWMETTDRITDAIQAGFDKQGSVYMMANSGAKGNISQIRQMAGLRGLMTNPSGR
HHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEECCCCCCCHHHHHHHHHCCCCCCCCCCC
IIDFPIKSSLREGLTTLEYFISTHGARKGLADTALRTSGSGYLTRRLIDVTQDVIILQED
EEECCCHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHCCCCCHHHHHHHHHHHCEEEEECC
CGTSNGTWIVEPKEKGMLPPLVDRVLGRWAAHNVVHPQTGEIIVGNNEEIDEAKAKAIGE
CCCCCCEEEECCHHCCCCCHHHHHHHHHHHHCCCCCCCCCCEEECCCCCHHHHHHHHHCC
AGITEVFVRSPLTCEATHGMCRRCYGRDLGRVRLVDMNTAVGIIAAQSIGEPGTQLTLRT
CCHHHHHHCCCCCCCHHHHHHHHHHCCCCCCEEEEECCCHHHHEEHHCCCCCCCEEEEEE
FHTGGVVGVDITTGLPRVEELFEARPPKVQSIISEIDGEAEVIENENGRHIRIFSDEVYQ
EECCCEEEEEECCCCHHHHHHHHCCCCHHHHHHHHCCCCEEEEECCCCCEEEEECHHHHC
DEYELPSGWKTQVQSGQWVDSGMVLASPEMEGKSKAVVQSDQNVVARVAGEVSVDGSLIT
CCCCCCCCCHHHCCCCCEECCCEEEECCCCCCCCCHHHHCCHHHHHHHHCCEEECCEEEE
IKYSESEEREYAIPAAMQIKVKTGDSVRAGQQLTDGSINPQDILSILGRDAVQKYLVEEV
EEECCCCCCCEECCCEEEEEEECCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHH
QKVYYSQGVHINDKHIEVIARQMLIKVRIDSSGDTDLVPGELVDKFRYEDINAKVLAEGG
HHHHHHCCCCCCHHHHHHHHHHHEEEEEECCCCCCCCCCHHHHHHHHCCCCCCEEEECCC
EPATAHTVLMGITRASLSTESWLAAASFQETTRVLTDAAIYGKVDKLSGLKENVIIGKLI
CCCHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHCCHHHHCCCCCCCEEECCC
PAQCKSCKEATVERAERIAAAAAAPAVSTLPENCL
HHHHHHHHHHHHHHHHHHHHHHHCCHHHCCCCCCC
>Mature Secondary Structure
MNEVNDFDAIRISLASPDQIRSWSYGEVTKPETINYRTLKPERDGLFCERIFGPIKDFEC
CCCCCCCCEEEEEECCCHHHCCCCCCCCCCCCCCCEEECCCCCCCCHHHHHHCCHHHHHH
ACGKYKRIRYKGIICDKCGVEIARAKVRRERMGHIELACPVGHIWFTRGIPSRVGLLLNL
HCCCCCEEEEEEEEECHHCHHHHHHHHHHHHCCCEEEECCCCCCCEECCCHHHHCEEEEC
STRSLERIIYYSHFIITGVNDEAREKAIKDLEVISSQRVADKGSEVDTRVAQMEAEDATV
CHHHHHHHHHHHEEEEECCCHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHCCCHHHH
EAINQVRRDFSTEREQMEEDIQLLIDQLKDLQIGNLLTENQYYELKQRFSNVFEASMGAE
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHCCCCCCCHHHHHHHHHHHHHHHHCCHH
ALLKLLSYIDMDKERSKLIQETRSTSGQRRKKAGKQLQLVEAFRRSSNKPEWMIMTVLPV
HHHHHHHHHCCCHHHHHHHHHHHHCCHHHHHHHCHHHHHHHHHHHCCCCCCEEEEEEECC
LPPDLRPMVQLDGGRFATSDLNDLYRRVINRNNRLQHLMEIGAPEIIIRNEKRMLQEAVD
CCCCCCCEEEECCCEEECCHHHHHHHHHHCCCHHHHHHHHCCCCEEEEECHHHHHHHHHH
SLIDNGRRGKSVAVNGDHKAKSLSDLLRGKQGRFRQNLLGKRVDYSGRSVIVVGPSLKLS
HHHHCCCCCCEEEECCCHHHHHHHHHHCCCCCHHHHHHHCCCCCCCCCEEEEECCCCCHH
QCGLPRRMALELFKPFVMHRLVRDGLAPNIKSARRLVERARPEVYDILEEVVKERPVMLN
HCCCCHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHCCHHHHHHHHHHHCCCEEEC
RAPTLHRLSIQAFEPVLIDGSALRLHPLVCSAFNADFDGDQMAVHVPLSKAAVKEARETM
CCCCCEEEEHHHCCCEEECCCCEEEHHHHHHHHCCCCCCCCEEEEECHHHHHHHHHHHHH
LSIHNMMLPSSGEPVVSPSLDMVFGCYYLTTTRPGAKGEGKIFSDFEEAKHYYEMGIIDL
HHHHHHHCCCCCCCCCCCCHHHHEEEEEEEECCCCCCCCCCCHHHHHHHHHHHHHHHHEE
RAIIKVRDGKGNMLETTTGRIIFNDVLPKEVEFQNMDIPKSAIKKIIGRCYKILSSQDMA
EEEEEEECCCCCEEEECCCCEEEECCCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCHH
VMLDKIKQLGFKYATSSGISIAMSDISVPREKAKLVAAADERTAISEGQFARGLITEDER
HHHHHHHHCCCHHCCCCCCEEEEECCCCCHHHHHEEEECCCHHHCCCCCHHCCCCCCCHH
YNSIIETWMETTDRITDAIQAGFDKQGSVYMMANSGAKGNISQIRQMAGLRGLMTNPSGR
HHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEECCCCCCCHHHHHHHHHCCCCCCCCCCC
IIDFPIKSSLREGLTTLEYFISTHGARKGLADTALRTSGSGYLTRRLIDVTQDVIILQED
EEECCCHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHCCCCCHHHHHHHHHHHCEEEEECC
CGTSNGTWIVEPKEKGMLPPLVDRVLGRWAAHNVVHPQTGEIIVGNNEEIDEAKAKAIGE
CCCCCCEEEECCHHCCCCCHHHHHHHHHHHHCCCCCCCCCCEEECCCCCHHHHHHHHHCC
AGITEVFVRSPLTCEATHGMCRRCYGRDLGRVRLVDMNTAVGIIAAQSIGEPGTQLTLRT
CCHHHHHHCCCCCCCHHHHHHHHHHCCCCCCEEEEECCCHHHHEEHHCCCCCCCEEEEEE
FHTGGVVGVDITTGLPRVEELFEARPPKVQSIISEIDGEAEVIENENGRHIRIFSDEVYQ
EECCCEEEEEECCCCHHHHHHHHCCCCHHHHHHHHCCCCEEEEECCCCCEEEEECHHHHC
DEYELPSGWKTQVQSGQWVDSGMVLASPEMEGKSKAVVQSDQNVVARVAGEVSVDGSLIT
CCCCCCCCCHHHCCCCCEECCCEEEECCCCCCCCCHHHHCCHHHHHHHHCCEEECCEEEE
IKYSESEEREYAIPAAMQIKVKTGDSVRAGQQLTDGSINPQDILSILGRDAVQKYLVEEV
EEECCCCCCCEECCCEEEEEEECCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHH
QKVYYSQGVHINDKHIEVIARQMLIKVRIDSSGDTDLVPGELVDKFRYEDINAKVLAEGG
HHHHHHCCCCCCHHHHHHHHHHHEEEEEECCCCCCCCCCHHHHHHHHCCCCCCEEEECCC
EPATAHTVLMGITRASLSTESWLAAASFQETTRVLTDAAIYGKVDKLSGLKENVIIGKLI
CCCHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHCCHHHHCCCCCCCEEECCC
PAQCKSCKEATVERAERIAAAAAAPAVSTLPENCL
HHHHHHHHHHHHHHHHHHHHHHHCCHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA