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The map label for this gene is ruvB

Identifier: 57234581

GI number: 57234581

Start: 562474

End: 563523

Strand: Direct

Name: ruvB

Synonym: DET0606

Alternate gene names: 57234581

Gene position: 562474-563523 (Clockwise)

Preceding gene: 57234591

Following gene: 57234580

Centisome position: 38.27

GC content: 51.81

Gene sequence:

>1050_bases
ATGTCAGAGGAAAAAGAGCGTCTTATATCCGGGAAACTGGCCGCCGATGATGCCAAGCTGGATACCAGTCTCCGCCCCCG
TTGCCTGTCTGATTTTATAGGTCAAAAACGCCTCAAGGATAATCTTGGGGTAGCCATACAGGCGGCCAAGCAAAGGGGAG
AGGCGCTGGACCATGTTTTGCTTTACGGGCCGCCGGGGCTGGGTAAAACCACTCTGTCCCATATAATAGCTTTGGAGATG
GGGGTGAATATCCGCATCACTTCCGGCCCGGCCATTGAAAGGCAGGGTGACCTGGCAGCTATTTTAACTAACCTTAAGCC
TTTTGATATTTTGTTTATAGATGAAATTCACCGCCTCAGCCGGAATGTGGAGGAAGTCCTTTACCCGGCTATGGAAGATT
ATGCACTTGACATAATGGTAGGAAAAGGGCCGGGTGCCAGAAGCCTGAGGCTGAAACTGCCTCACTTTACCCTGATAGGG
GCGACTACCCGCTATGCCATGCTTTCCGCACCTCTGCGTGACCGTTTCGGTTCTATATTCCGGTTGGATTTTTATGACGA
AGATGCCATTCATGATATTGTCAGCCGTTCTGCCCATATACTGGGGGTGGAGGCGGAAGAAAACGGTATCCGCCAGATAG
CCTGCCGTTCCCGCGGCACTCCCAGAGTAGCTAACCGTCTGCTTCGGCGGGTGAGGGATTATGCTCAGGTAAAAGGAAAC
GGGCTGATTACCGGGGATATGGCAGCAGAGTCTCTGGCCTGTCTGGAAGTAGACCGTTTGGGGCTTGATGAGATTGACCA
CAAGGTTTTAAAAACCATTATCCATAAATTCGGCGGTGGGCCGGTAGGGCTTGAAACCATTGCCGCCGCTATTTCCGAAG
AGGCAGATACTATTATGGACGTTTACGAACCGTATCTGCTCCAACTGGGTTTTCTGGAAAGAACACCCAGAGGGCGTCAG
GCGACCCGTCTGGCCTACCAGCACTTGAATATACCTTACCCGGCTGATAAAAATAACCAGCAGGGGCTTTGGGCGGAGAA
TGGCACCTAA

Upstream 100 bases:

>100_bases
GCCTGTTTTATCAGTCCGCAAGGCATATGACCCGTCAAACACCCCCTTTAAAGCCCGATTATTGAGGGCGTTTTGGAATA
TTTGTGCTATAATATTTCAA

Downstream 100 bases:

>100_bases
ACTTCTCCTTCATGGCTGTTGCGCCCACTGTACCGCTTACTCTTTTAAATACTGGCAGGAACAGGGTTTTGCGGTCAGTG
TTTACTGGTATAACCCTAAT

Product: Holliday junction DNA helicase RuvB

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 349; Mature: 348

Protein sequence:

>349_residues
MSEEKERLISGKLAADDAKLDTSLRPRCLSDFIGQKRLKDNLGVAIQAAKQRGEALDHVLLYGPPGLGKTTLSHIIALEM
GVNIRITSGPAIERQGDLAAILTNLKPFDILFIDEIHRLSRNVEEVLYPAMEDYALDIMVGKGPGARSLRLKLPHFTLIG
ATTRYAMLSAPLRDRFGSIFRLDFYDEDAIHDIVSRSAHILGVEAEENGIRQIACRSRGTPRVANRLLRRVRDYAQVKGN
GLITGDMAAESLACLEVDRLGLDEIDHKVLKTIIHKFGGGPVGLETIAAAISEEADTIMDVYEPYLLQLGFLERTPRGRQ
ATRLAYQHLNIPYPADKNNQQGLWAENGT

Sequences:

>Translated_349_residues
MSEEKERLISGKLAADDAKLDTSLRPRCLSDFIGQKRLKDNLGVAIQAAKQRGEALDHVLLYGPPGLGKTTLSHIIALEM
GVNIRITSGPAIERQGDLAAILTNLKPFDILFIDEIHRLSRNVEEVLYPAMEDYALDIMVGKGPGARSLRLKLPHFTLIG
ATTRYAMLSAPLRDRFGSIFRLDFYDEDAIHDIVSRSAHILGVEAEENGIRQIACRSRGTPRVANRLLRRVRDYAQVKGN
GLITGDMAAESLACLEVDRLGLDEIDHKVLKTIIHKFGGGPVGLETIAAAISEEADTIMDVYEPYLLQLGFLERTPRGRQ
ATRLAYQHLNIPYPADKNNQQGLWAENGT
>Mature_348_residues
SEEKERLISGKLAADDAKLDTSLRPRCLSDFIGQKRLKDNLGVAIQAAKQRGEALDHVLLYGPPGLGKTTLSHIIALEMG
VNIRITSGPAIERQGDLAAILTNLKPFDILFIDEIHRLSRNVEEVLYPAMEDYALDIMVGKGPGARSLRLKLPHFTLIGA
TTRYAMLSAPLRDRFGSIFRLDFYDEDAIHDIVSRSAHILGVEAEENGIRQIACRSRGTPRVANRLLRRVRDYAQVKGNG
LITGDMAAESLACLEVDRLGLDEIDHKVLKTIIHKFGGGPVGLETIAAAISEEADTIMDVYEPYLLQLGFLERTPRGRQA
TRLAYQHLNIPYPADKNNQQGLWAENGT

Specific function: The ruvA-ruvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is an helicase that mediates the Holliday

COG id: COG2255

COG function: function code L; Holliday junction resolvasome, helicase subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ruvB family

Homologues:

Organism=Escherichia coli, GI1788167, Length=331, Percent_Identity=58.3081570996979, Blast_Score=397, Evalue=1e-112,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): RUVB_DEHE1 (Q3Z8V1)

Other databases:

- EMBL:   CP000027
- RefSeq:   YP_181348.1
- ProteinModelPortal:   Q3Z8V1
- SMR:   Q3Z8V1
- STRING:   Q3Z8V1
- GeneID:   3230049
- GenomeReviews:   CP000027_GR
- KEGG:   det:DET0606
- NMPDR:   fig|243164.3.peg.463
- TIGR:   DET0606
- eggNOG:   COG2255
- HOGENOM:   HBG339960
- OMA:   EKFDGGP
- PhylomeDB:   Q3Z8V1
- ProtClustDB:   PRK00080
- BioCyc:   DETH243164:DET_0606-MONOMER
- HAMAP:   MF_00016
- InterPro:   IPR003593
- InterPro:   IPR004605
- InterPro:   IPR008823
- InterPro:   IPR008824
- InterPro:   IPR011991
- Gene3D:   G3DSA:1.10.10.10
- ProDom:   PD005323
- SMART:   SM00382
- TIGRFAMs:   TIGR00635

Pfam domain/function: PF05491 RuvB_C; PF05496 RuvB_N

EC number: =3.6.4.12

Molecular weight: Translated: 38615; Mature: 38484

Theoretical pI: Translated: 6.80; Mature: 6.80

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSEEKERLISGKLAADDAKLDTSLRPRCLSDFIGQKRLKDNLGVAIQAAKQRGEALDHVL
CCHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCHHHHHHHHHCHHHCEEE
LYGPPGLGKTTLSHIIALEMGVNIRITSGPAIERQGDLAAILTNLKPFDILFIDEIHRLS
EECCCCCCHHHHHHHHHHEECCEEEECCCCCCCCCCCHHHHHHCCCCCEEEHHHHHHHHH
RNVEEVLYPAMEDYALDIMVGKGPGARSLRLKLPHFTLIGATTRYAMLSAPLRDRFGSIF
HHHHHHHHHHHHCEEEEEEEECCCCCCEEEEECCCEEEEECHHHHHHHHCCHHHHCCCEE
RLDFYDEDAIHDIVSRSAHILGVEAEENGIRQIACRSRGTPRVANRLLRRVRDYAQVKGN
EEECCCCHHHHHHHHCCCEEEEEECCCCCHHHHHHHCCCCHHHHHHHHHHHHHHHHHCCC
GLITGDMAAESLACLEVDRLGLDEIDHKVLKTIIHKFGGGPVGLETIAAAISEEADTIMD
EEEEECHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHH
VYEPYLLQLGFLERTPRGRQATRLAYQHLNIPYPADKNNQQGLWAENGT
HHHHHHHHHHHHHCCCCCHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCC
>Mature Secondary Structure 
SEEKERLISGKLAADDAKLDTSLRPRCLSDFIGQKRLKDNLGVAIQAAKQRGEALDHVL
CHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCHHHHHHHHHCHHHCEEE
LYGPPGLGKTTLSHIIALEMGVNIRITSGPAIERQGDLAAILTNLKPFDILFIDEIHRLS
EECCCCCCHHHHHHHHHHEECCEEEECCCCCCCCCCCHHHHHHCCCCCEEEHHHHHHHHH
RNVEEVLYPAMEDYALDIMVGKGPGARSLRLKLPHFTLIGATTRYAMLSAPLRDRFGSIF
HHHHHHHHHHHHCEEEEEEEECCCCCCEEEEECCCEEEEECHHHHHHHHCCHHHHCCCEE
RLDFYDEDAIHDIVSRSAHILGVEAEENGIRQIACRSRGTPRVANRLLRRVRDYAQVKGN
EEECCCCHHHHHHHHCCCEEEEEECCCCCHHHHHHHCCCCHHHHHHHHHHHHHHHHHCCC
GLITGDMAAESLACLEVDRLGLDEIDHKVLKTIIHKFGGGPVGLETIAAAISEEADTIMD
EEEEECHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHH
VYEPYLLQLGFLERTPRGRQATRLAYQHLNIPYPADKNNQQGLWAENGT
HHHHHHHHHHHHHCCCCCHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA