Click here to switch to the map view.

The map label for this gene is kynB [H]

Identifier: 57234555

GI number: 57234555

Start: 623972

End: 624598

Strand: Direct

Name: kynB [H]

Synonym: DET0675

Alternate gene names: 57234555

Gene position: 623972-624598 (Clockwise)

Preceding gene: 57234556

Following gene: 57234554

Centisome position: 42.46

GC content: 47.21

Gene sequence:

>627_bases
ATGAAAAAGATTTATGACTTAAGCCCCGAAATACGCCCTGAAATGATTAGCTGGCCGGGTGATGGCCCTCCGCAGATAAA
GCTTTTGCATAGTATCAGGGGTGGTTTTCCCACCAACCTCGGTCAGCTTACCATGACATTACATAACGGCAGCCATATTG
ATGCCCCCCTCCATTTTTTTGAAGATGGCGATGGGGTGGGTGAGATACCCCTTGAGATACTTATTGGCAATGTCCGTGTT
TTGTGCTTTAGCGGGGTGAAAACTATAACCCGTGATATGCTTGAGCAGGCTGAACTAAGGGGGGTAACCCGGCTTATACT
GGCTACGGATAATGAAACCCTTTGGGATAAGCCTGATTTTGACCGGAACTATACTTATATAGACATCGGGGCTGCCCGTT
ATCTGACCGAGATAGGTATACGCCTGCTGGGTATAGATTACCTTTCGGTAGAGGATTTTGAAGAGACTCAGGGAGTGCAC
AAGCACCTTTTAAGCCGTGGGGTAGTTATATTGGAAAGTCTGCAGCTTGCAGGTGTGGCTGAAGGGGATTATGAGCTTTT
TTGCCTGCCCTTGAAACTGGGTAAAGTAGACGGTGCCCCCGCCAGAGTAATATTAATAGAGAGATAA

Upstream 100 bases:

>100_bases
TTGAAAATTCCCCGCGCCCCATGCTGTTATGGCGGAACAGCATTTAAACTTTGCTTGACACTTGCCTTTACTCCTTCCTA
CAATTAGACAAGAAAAAGGC

Downstream 100 bases:

>100_bases
CAGTTTGAAAGACGTAAAGATAGTGCCGGCTGTACTTACCGATGACCCTGCGGCCTTTGAGTGTATGCTAAACCAGCTGG
AGAGTTTTGCTCCTTCTGCC

Product: cyclase, putative

Products: NA

Alternate protein names: KFA; N-formylkynurenine formamidase [H]

Number of amino acids: Translated: 208; Mature: 208

Protein sequence:

>208_residues
MKKIYDLSPEIRPEMISWPGDGPPQIKLLHSIRGGFPTNLGQLTMTLHNGSHIDAPLHFFEDGDGVGEIPLEILIGNVRV
LCFSGVKTITRDMLEQAELRGVTRLILATDNETLWDKPDFDRNYTYIDIGAARYLTEIGIRLLGIDYLSVEDFEETQGVH
KHLLSRGVVILESLQLAGVAEGDYELFCLPLKLGKVDGAPARVILIER

Sequences:

>Translated_208_residues
MKKIYDLSPEIRPEMISWPGDGPPQIKLLHSIRGGFPTNLGQLTMTLHNGSHIDAPLHFFEDGDGVGEIPLEILIGNVRV
LCFSGVKTITRDMLEQAELRGVTRLILATDNETLWDKPDFDRNYTYIDIGAARYLTEIGIRLLGIDYLSVEDFEETQGVH
KHLLSRGVVILESLQLAGVAEGDYELFCLPLKLGKVDGAPARVILIER
>Mature_208_residues
MKKIYDLSPEIRPEMISWPGDGPPQIKLLHSIRGGFPTNLGQLTMTLHNGSHIDAPLHFFEDGDGVGEIPLEILIGNVRV
LCFSGVKTITRDMLEQAELRGVTRLILATDNETLWDKPDFDRNYTYIDIGAARYLTEIGIRLLGIDYLSVEDFEETQGVH
KHLLSRGVVILESLQLAGVAEGDYELFCLPLKLGKVDGAPARVILIER

Specific function: Catalyzes the hydrolysis of N-formyl-L-kynurenine to L- kynurenine [H]

COG id: COG1878

COG function: function code R; Predicted metal-dependent hydrolase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the kynB family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR017484
- InterPro:   IPR007325 [H]

Pfam domain/function: PF04199 Cyclase [H]

EC number: =3.5.1.9 [H]

Molecular weight: Translated: 23193; Mature: 23193

Theoretical pI: Translated: 4.72; Mature: 4.72

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKKIYDLSPEIRPEMISWPGDGPPQIKLLHSIRGGFPTNLGQLTMTLHNGSHIDAPLHFF
CCCCCCCCCCCCCCEEECCCCCCHHHHHEEHHCCCCCCCCCEEEEEEECCCCCCCCEEEE
EDGDGVGEIPLEILIGNVRVLCFSGVKTITRDMLEQAELRGVTRLILATDNETLWDKPDF
ECCCCCCCCEEEEEECCEEEEEECCHHHHHHHHHHHHHHCCEEEEEEECCCCCCCCCCCC
DRNYTYIDIGAARYLTEIGIRLLGIDYLSVEDFEETQGVHKHLLSRGVVILESLQLAGVA
CCCEEEEEEHHHHHHHHHCCEEEEEEEECCCCCHHHHHHHHHHHHCCCEEEEHHHHCEEC
EGDYELFCLPLKLGKVDGAPARVILIER
CCCCEEEEEEEEECCCCCCCEEEEEEEC
>Mature Secondary Structure
MKKIYDLSPEIRPEMISWPGDGPPQIKLLHSIRGGFPTNLGQLTMTLHNGSHIDAPLHFF
CCCCCCCCCCCCCCEEECCCCCCHHHHHEEHHCCCCCCCCCEEEEEEECCCCCCCCEEEE
EDGDGVGEIPLEILIGNVRVLCFSGVKTITRDMLEQAELRGVTRLILATDNETLWDKPDF
ECCCCCCCCEEEEEECCEEEEEECCHHHHHHHHHHHHHHCCEEEEEEECCCCCCCCCCCC
DRNYTYIDIGAARYLTEIGIRLLGIDYLSVEDFEETQGVHKHLLSRGVVILESLQLAGVA
CCCEEEEEEHHHHHHHHHCCEEEEEEEECCCCCHHHHHHHHHHHHCCCEEEEHHHHCEEC
EGDYELFCLPLKLGKVDGAPARVILIER
CCCCEEEEEEEEECCCCCCCEEEEEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA