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The map label for this gene is adcA [H]

Identifier: 57234535

GI number: 57234535

Start: 585345

End: 586217

Strand: Direct

Name: adcA [H]

Synonym: DET0631

Alternate gene names: 57234535

Gene position: 585345-586217 (Clockwise)

Preceding gene: 57234543

Following gene: 57234534

Centisome position: 39.83

GC content: 44.56

Gene sequence:

>873_bases
ATGAAATTAAGGACATTATTTTTGAGTTTGGCTTTAGGCGTTACCCTGCTTAGCAGTTTACTGCTGGCGGGTTGTCAGGA
AGATTCATCTTCTGCTGCCAAGCTCAAAATTGCAGTCAGTATAGTGCCCCTGAAAGAATTTACCCAGCAAATTGCCGGGG
ATAAGGCTGAAGTAATTCTTATGGTTCCTCCCGGGGCGGAGCCGCATACCTACCAGCCGCTTCCTTCCCAAATGGTAGAT
ATAAGCCAGGCAGATATGTACGTGAAGCTGGGCTCTGATTTTGGTTTTGAGCAAACCTGGATTTCAAAAATATTGGCTTT
AAACCACTCTATGCTGATGGTAGATAGTTCGGTAAATATTACACTGGAAAGCAGTTCGGAAGGTGACGGGGCAGACCCGC
ATATCTGGCTTTCACCGCGTAATGCTATCCAGATGGTCAAAAATATCACTACGGGGCTGATGAGCCTGGACCCGGAAAAC
AAGAGCTATTATGTAGCCAACCGGGATGCTTATTTAGCAAAGCTTGAGCAGTTGGATAATGAAATAACCCTGGCTCTCAG
CCACCTGCATAACCGTACCTTTCTGGTTTTTCATCCTGCCTGGGCTTATTTTGCCAGAGACTATAATCTGAAAGAACTTT
CCATTGAAATAGAAGGCAAAGAACCCACCCCCCAGCAGATGATAGAAATAATAGATTTGGCTATACAAAATAATATCAGC
ATTGTCTTTGCTTCCCCCCAATTTTCCAGCCGGAGTGCAGAGTCAATTGCCTCTGAAATAGGCGGGCAGGTGATAATGAT
AGACCCGCTGGCCCAAGATTACATAAAGAATATGGAATTTGTTTACAAGCAAATGCAAGAGGTTATGAGCTGA

Upstream 100 bases:

>100_bases
TTACGGAAAATTTGTCCCGGCAGACCGGGTTTGCTATAGATGCCCATTTGCTGGAGTTTATCGGGCGTTGCCGGAATTGT
CAGAAAGAGGCGGGGAAAGT

Downstream 100 bases:

>100_bases
AAATGTCTGACACGCCAGCCCTGGTGTTTAGGGGAGTTAGTGCCGGTTTTGACGGCCTTACAGTACTGGAAGATATTACT
TTTTCCCAGCCTGCAGGACG

Product: cation ABC transporter, periplasmc-binding protein

Products: Zn (II) [Cytoplasm]; ADP; phosphate [C]

Alternate protein names: NA

Number of amino acids: Translated: 290; Mature: 290

Protein sequence:

>290_residues
MKLRTLFLSLALGVTLLSSLLLAGCQEDSSSAAKLKIAVSIVPLKEFTQQIAGDKAEVILMVPPGAEPHTYQPLPSQMVD
ISQADMYVKLGSDFGFEQTWISKILALNHSMLMVDSSVNITLESSSEGDGADPHIWLSPRNAIQMVKNITTGLMSLDPEN
KSYYVANRDAYLAKLEQLDNEITLALSHLHNRTFLVFHPAWAYFARDYNLKELSIEIEGKEPTPQQMIEIIDLAIQNNIS
IVFASPQFSSRSAESIASEIGGQVIMIDPLAQDYIKNMEFVYKQMQEVMS

Sequences:

>Translated_290_residues
MKLRTLFLSLALGVTLLSSLLLAGCQEDSSSAAKLKIAVSIVPLKEFTQQIAGDKAEVILMVPPGAEPHTYQPLPSQMVD
ISQADMYVKLGSDFGFEQTWISKILALNHSMLMVDSSVNITLESSSEGDGADPHIWLSPRNAIQMVKNITTGLMSLDPEN
KSYYVANRDAYLAKLEQLDNEITLALSHLHNRTFLVFHPAWAYFARDYNLKELSIEIEGKEPTPQQMIEIIDLAIQNNIS
IVFASPQFSSRSAESIASEIGGQVIMIDPLAQDYIKNMEFVYKQMQEVMS
>Mature_290_residues
MKLRTLFLSLALGVTLLSSLLLAGCQEDSSSAAKLKIAVSIVPLKEFTQQIAGDKAEVILMVPPGAEPHTYQPLPSQMVD
ISQADMYVKLGSDFGFEQTWISKILALNHSMLMVDSSVNITLESSSEGDGADPHIWLSPRNAIQMVKNITTGLMSLDPEN
KSYYVANRDAYLAKLEQLDNEITLALSHLHNRTFLVFHPAWAYFARDYNLKELSIEIEGKEPTPQQMIEIIDLAIQNNIS
IVFASPQFSSRSAESIASEIGGQVIMIDPLAQDYIKNMEFVYKQMQEVMS

Specific function: Part of the high-affinity ABC transporter complex AdcABC involved in zinc import (Probable) [H]

COG id: COG0803

COG function: function code P; ABC-type metal ion transport system, periplasmic component/surface adhesin

Gene ontology:

Cell location: Cell membrane; Lipid-anchor (Probable) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the bacterial solute-binding protein 9 family [H]

Homologues:

Organism=Escherichia coli, GI87081990, Length=266, Percent_Identity=25.187969924812, Blast_Score=85, Evalue=5e-18,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006127
- InterPro:   IPR006129
- InterPro:   IPR006128 [H]

Pfam domain/function: PF01297 SBP_bac_9 [H]

EC number: NA

Molecular weight: Translated: 32231; Mature: 32231

Theoretical pI: Translated: 4.53; Mature: 4.53

Prosite motif: PS00013 PROKAR_LIPOPROTEIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
4.5 %Met     (Translated Protein)
4.8 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
4.5 %Met     (Mature Protein)
4.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKLRTLFLSLALGVTLLSSLLLAGCQEDSSSAAKLKIAVSIVPLKEFTQQIAGDKAEVIL
CCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEEEEEEEECHHHHHHHHCCCCCEEEE
MVPPGAEPHTYQPLPSQMVDISQADMYVKLGSDFGFEQTWISKILALNHSMLMVDSSVNI
EECCCCCCCCCCCCCHHHHCCCCCCEEEEECCCCCCHHHHHHHHHHHCCCEEEEECCEEE
TLESSSEGDGADPHIWLSPRNAIQMVKNITTGLMSLDPENKSYYVANRDAYLAKLEQLDN
EEECCCCCCCCCCEEEECCHHHHHHHHHHHHHHHCCCCCCCEEEEECCHHHHHHHHHCCC
EITLALSHLHNRTFLVFHPAWAYFARDYNLKELSIEIEGKEPTPQQMIEIIDLAIQNNIS
HHHHHHHHHCCCEEEEECCHHHHHHCCCCEEEEEEEEECCCCCHHHHHHHHHHHHCCCEE
IVFASPQFSSRSAESIASEIGGQVIMIDPLAQDYIKNMEFVYKQMQEVMS
EEEECCCCCCCHHHHHHHHHCCEEEEECHHHHHHHHHHHHHHHHHHHHHC
>Mature Secondary Structure
MKLRTLFLSLALGVTLLSSLLLAGCQEDSSSAAKLKIAVSIVPLKEFTQQIAGDKAEVIL
CCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEEEEEEEECHHHHHHHHCCCCCEEEE
MVPPGAEPHTYQPLPSQMVDISQADMYVKLGSDFGFEQTWISKILALNHSMLMVDSSVNI
EECCCCCCCCCCCCCHHHHCCCCCCEEEEECCCCCCHHHHHHHHHHHCCCEEEEECCEEE
TLESSSEGDGADPHIWLSPRNAIQMVKNITTGLMSLDPENKSYYVANRDAYLAKLEQLDN
EEECCCCCCCCCCEEEECCHHHHHHHHHHHHHHHCCCCCCCEEEEECCHHHHHHHHHCCC
EITLALSHLHNRTFLVFHPAWAYFARDYNLKELSIEIEGKEPTPQQMIEIIDLAIQNNIS
HHHHHHHHHCCCEEEEECCHHHHHHCCCCEEEEEEEEECCCCCHHHHHHHHHHHHCCCEE
IVFASPQFSSRSAESIASEIGGQVIMIDPLAQDYIKNMEFVYKQMQEVMS
EEEECCCCCCCHHHHHHHHHCCEEEEECHHHHHHHHHHHHHHHHHHHHHC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Zn (II) [Periplasm]; H2O; ATP [C]

Specific reaction: Zn (II) [Periplasm] + H2O + ATP = Zn (II) [Cytoplasm] + ADP + phosphate [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 9274031; 9384377; 9811636 [H]