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The map label for this gene is cobD-3 [H]

Identifier: 57234525

GI number: 57234525

Start: 634376

End: 635302

Strand: Direct

Name: cobD-3 [H]

Synonym: DET0688

Alternate gene names: 57234525

Gene position: 634376-635302 (Clockwise)

Preceding gene: 57234526

Following gene: 57234524

Centisome position: 43.16

GC content: 49.73

Gene sequence:

>927_bases
TTGGAAGTCCTTTTTATATTCCTGCTGGCGCTCATTATTGATTTGGTTTTTGGAGACCCGCCTAATGCTTTTCATCCGGT
AGCCTATATGGGCAGGGTAATTGCCCTTTTTGAGCGGGCAGGGTTTAAGGGCGGTAGGGTCTACCAGTTTGTTTACGGTA
TAGTCATGGTTTTTATTGCCATGGCACTTTTTTTTATACCGGTATATTTTCTGCTGGACTGGCTGCATGGAGTAAACAGT
GTAGTTTACATAATAGTGTCGGCCGTTTTACTCAAGATGTGTTTTACGGTAACCGGCTTGCGTAAGGCCGCTTTGCTGAT
TAAACAATTGTTAGAAAAAGATGACATTGCCCAGGCCCGTTTTGAGCTCCGCTCACTGGTTTCACGTGATACCTCCAAAC
TGCCTCAGCCCAAACTGGTGGCGGCGGCGGTGGAATCTGTGGCGGAGAGTATCGGAGACGGGTTTGTGGCGCCGCTCTTT
TTCTTTCTGATATTCGGCGTGCCCGGTGTTATGGCCTACCGGGTAGTTAGCACCTTTGACAGCATGGTGGGTTACCGCGG
CAAATACGAATATCTGGGCAAGTTTGCCGCCAGATTTGATGATGTGCTTAATTTTATTCCGGCCAGACTGTCTGCCTTGT
GCATACTGATTGCCAGCTTATTTGGGCGTTACAGCCCGGCAGGGGCATGGCGGATAATGTGGCGTGACCACGCCAAGACC
CAAAGCCCCAATGCCGGCTGGCCAATGGCGACTGCGGCCGGTGCCCTTGAAGTTTGTCTGGAAAAAGTGGGACACTACTC
ACTGGGGGATAATATCAGGGAGCTTGTTCCCCAAACTATCAGCCGTTCGCTGCTGCTTATAAACAGTGCGGCCTTTATCT
GGGTTTTAATAAGCGCGGGAGTGATTTATTTTGTCCGTATCGCCTAA

Upstream 100 bases:

>100_bases
GGCGGGCATACTTTGCTGGGTGAACTGATGGGGCGGAGTGTTACCCTGGCTATAAAAGAAGCCCTGACCAAGCGTATGGC
CAGCAGAAAAGGGCATTAGG

Downstream 100 bases:

>100_bases
GCCGCAGGTAGAAAAATTAAAGCCGTGTTACCACGGCGGGCCGAACTATGCCGAGCTTAGAAAACTGGGTATCAGCCCGG
ATGCGGTTATGGATTTTTCG

Product: cobalamin biosynthesis protein CobD

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 308; Mature: 308

Protein sequence:

>308_residues
MEVLFIFLLALIIDLVFGDPPNAFHPVAYMGRVIALFERAGFKGGRVYQFVYGIVMVFIAMALFFIPVYFLLDWLHGVNS
VVYIIVSAVLLKMCFTVTGLRKAALLIKQLLEKDDIAQARFELRSLVSRDTSKLPQPKLVAAAVESVAESIGDGFVAPLF
FFLIFGVPGVMAYRVVSTFDSMVGYRGKYEYLGKFAARFDDVLNFIPARLSALCILIASLFGRYSPAGAWRIMWRDHAKT
QSPNAGWPMATAAGALEVCLEKVGHYSLGDNIRELVPQTISRSLLLINSAAFIWVLISAGVIYFVRIA

Sequences:

>Translated_308_residues
MEVLFIFLLALIIDLVFGDPPNAFHPVAYMGRVIALFERAGFKGGRVYQFVYGIVMVFIAMALFFIPVYFLLDWLHGVNS
VVYIIVSAVLLKMCFTVTGLRKAALLIKQLLEKDDIAQARFELRSLVSRDTSKLPQPKLVAAAVESVAESIGDGFVAPLF
FFLIFGVPGVMAYRVVSTFDSMVGYRGKYEYLGKFAARFDDVLNFIPARLSALCILIASLFGRYSPAGAWRIMWRDHAKT
QSPNAGWPMATAAGALEVCLEKVGHYSLGDNIRELVPQTISRSLLLINSAAFIWVLISAGVIYFVRIA
>Mature_308_residues
MEVLFIFLLALIIDLVFGDPPNAFHPVAYMGRVIALFERAGFKGGRVYQFVYGIVMVFIAMALFFIPVYFLLDWLHGVNS
VVYIIVSAVLLKMCFTVTGLRKAALLIKQLLEKDDIAQARFELRSLVSRDTSKLPQPKLVAAAVESVAESIGDGFVAPLF
FFLIFGVPGVMAYRVVSTFDSMVGYRGKYEYLGKFAARFDDVLNFIPARLSALCILIASLFGRYSPAGAWRIMWRDHAKT
QSPNAGWPMATAAGALEVCLEKVGHYSLGDNIRELVPQTISRSLLLINSAAFIWVLISAGVIYFVRIA

Specific function: Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group [H]

COG id: COG1270

COG function: function code H; Cobalamin biosynthesis protein CobD/CbiB

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the CobD/CbiB family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004485 [H]

Pfam domain/function: PF03186 CobD_Cbib [H]

EC number: NA

Molecular weight: Translated: 34172; Mature: 34172

Theoretical pI: Translated: 9.41; Mature: 9.41

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure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HHHHHCCC
>Mature Secondary Structure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HHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA