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The map label for this gene is panD

Identifier: 57234380

GI number: 57234380

Start: 737060

End: 737434

Strand: Direct

Name: panD

Synonym: DET0802

Alternate gene names: 57234380

Gene position: 737060-737434 (Clockwise)

Preceding gene: 57234381

Following gene: 57234371

Centisome position: 50.15

GC content: 47.73

Gene sequence:

>375_bases
ATGCTCAAAAGCAAAATCCACCGGGCTACCATTACCGATGCCTGCATAGACTATGAAGGCAGTATTACCATTGATAAAAA
CCTTATGCAGGCAGCCAACTTGCTGCCCTACGAACAGGTGCATGTGGTAAATGTAAATAACGGAACGCGGCTGGAGACCT
ATGTCATAGAGGGCCCGGCTGGCAGCGGGCAGATATGCTTAAACGGGGCAGCTGCCCGTATGGGAATGAAGGGTGATAAA
GTAATTATACTGGGCTACAGTCTGATTACCGAAGAAGATACCCTTACCCACCAGCCGAATCTGGTCTATGTAGACAGTCT
TAACCGCATAACCAAAGTTAAAAACGGGGTTGCCAGCCGGAATTTAGAGGTATAA

Upstream 100 bases:

>100_bases
ACTGTTAAAATAGCGCTTGATAAGGAAAACCCCAATCTGGCTGGCATAGAAAAAGTATCCGAGATACTGGCAAATTAAGG
AGACATATACAGTGAGAATC

Downstream 100 bases:

>100_bases
ACAGATGCGCACCACCATCAGCCAGCTAAAGGAAATGAAACAGAACAAGCAGAAGATAGCCATGCTGACTGCATATGACT
ATCCCACTGCCCAAATACTG

Product: aspartate alpha-decarboxylase

Products: NA

Alternate protein names: Aspartate alpha-decarboxylase

Number of amino acids: Translated: 124; Mature: 124

Protein sequence:

>124_residues
MLKSKIHRATITDACIDYEGSITIDKNLMQAANLLPYEQVHVVNVNNGTRLETYVIEGPAGSGQICLNGAAARMGMKGDK
VIILGYSLITEEDTLTHQPNLVYVDSLNRITKVKNGVASRNLEV

Sequences:

>Translated_124_residues
MLKSKIHRATITDACIDYEGSITIDKNLMQAANLLPYEQVHVVNVNNGTRLETYVIEGPAGSGQICLNGAAARMGMKGDK
VIILGYSLITEEDTLTHQPNLVYVDSLNRITKVKNGVASRNLEV
>Mature_124_residues
MLKSKIHRATITDACIDYEGSITIDKNLMQAANLLPYEQVHVVNVNNGTRLETYVIEGPAGSGQICLNGAAARMGMKGDK
VIILGYSLITEEDTLTHQPNLVYVDSLNRITKVKNGVASRNLEV

Specific function: Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine

COG id: COG0853

COG function: function code H; Aspartate 1-decarboxylase

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the panD family

Homologues:

Organism=Escherichia coli, GI1786323, Length=117, Percent_Identity=37.6068376068376, Blast_Score=91, Evalue=3e-20,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): PAND_DEHE1 (Q3Z8B5)

Other databases:

- EMBL:   CP000027
- RefSeq:   YP_181534.1
- ProteinModelPortal:   Q3Z8B5
- SMR:   Q3Z8B5
- STRING:   Q3Z8B5
- GeneID:   3229847
- GenomeReviews:   CP000027_GR
- KEGG:   det:DET0802
- NMPDR:   fig|243164.3.peg.994
- TIGR:   DET0802
- eggNOG:   COG0853
- HOGENOM:   HBG302821
- OMA:   LYSKIHR
- PhylomeDB:   Q3Z8B5
- ProtClustDB:   PRK05449
- BioCyc:   DETH243164:DET_0802-MONOMER
- GO:   GO:0005737
- GO:   GO:0005488
- HAMAP:   MF_00446
- InterPro:   IPR009010
- InterPro:   IPR003190
- Gene3D:   G3DSA:2.40.40.20
- PANTHER:   PTHR21012
- PIRSF:   PIRSF006246
- ProDom:   PD009294
- TIGRFAMs:   TIGR00223

Pfam domain/function: PF02261 Asp_decarbox; SSF50692 Asp_decarb_fold

EC number: =4.1.1.11

Molecular weight: Translated: 13530; Mature: 13530

Theoretical pI: Translated: 6.78; Mature: 6.78

Prosite motif: NA

Important sites: ACT_SITE 21-21 ACT_SITE 54-54 BINDING 53-53

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
4.8 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
4.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLKSKIHRATITDACIDYEGSITIDKNLMQAANLLPYEQVHVVNVNNGTRLETYVIEGPA
CCCCCCCEEEECHHHCCCCCCEEECHHHHHHHHCCCCCEEEEEECCCCCEEEEEEEECCC
GSGQICLNGAAARMGMKGDKVIILGYSLITEEDTLTHQPNLVYVDSLNRITKVKNGVASR
CCCEEEEECCHHCCCCCCCEEEEEEEEEECCCCCCCCCCCEEEECCCCHHHHHHCCCCCC
NLEV
CCCC
>Mature Secondary Structure
MLKSKIHRATITDACIDYEGSITIDKNLMQAANLLPYEQVHVVNVNNGTRLETYVIEGPA
CCCCCCCEEEECHHHCCCCCCEEECHHHHHHHHCCCCCEEEEEECCCCCEEEEEEEECCC
GSGQICLNGAAARMGMKGDKVIILGYSLITEEDTLTHQPNLVYVDSLNRITKVKNGVASR
CCCEEEEECCHHCCCCCCCEEEEEEEEEECCCCCCCCCCCEEEECCCCHHHHHHCCCCCC
NLEV
CCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA