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The map label for this gene is mod [H]

Identifier: 57234105

GI number: 57234105

Start: 1015763

End: 1017526

Strand: Direct

Name: mod [H]

Synonym: DET1112

Alternate gene names: 57234105

Gene position: 1015763-1017526 (Clockwise)

Preceding gene: 57234106

Following gene: 57234104

Centisome position: 69.11

GC content: 44.1

Gene sequence:

>1764_bases
ATGGATAAAATGAGAATGGAGTCAGTTGACATGACCGAGAAAAACATCGACAGGATTGCTGCCCTGTTTCCGAATTGCAT
CACCGAGACCGTAGACGAGGAGCGCAGCACTCCCGACAAAAAGGTCTACAAGAAGGCGGTTAACTTTGAGCTTCTCCGGC
AGATGCTATCCGGTGATGTGCTGGAGGGCGACGAGGCCTATGAGTTTACATGGGTTGGTAAGAAAGCGGCCATAGTCGAA
GCCAATAAGCCCATCCGCAAGACTCTGCGTCCGTGCCCAGAGGAGAGTGTAAATTGGGACTCCACAGAGAATTTGTATAT
CGAAGGTGACAATCTCGAAGTCCTCAAGCTCATACAGGAGAGCTATATGGGGAAAGTGAAACTAATCTTTATTGATCCGC
CATACAATACGGGCAGCGATTTCATCTATGCAGATGACTTTGCAGTTGGCTCAGCGGAGTACAGTGATGAAATTGGTGAG
GTGGATGCAGACGGGAATAGACTTTTTAAGAATACAGATTCCAATGGGAGGTTCCATTCTGATTGGTGCTCGATGATGTA
TTCAAGGCTCATGCTCGCCAGAAATCTCCTTACAGACGACGGAAGCATTTTTATAAGTATTGATTTTAATGAAGTCGAAA
ACCTGAAGAAGATAATGGATGAGGTTTTTGGAGCAGAGAATTTTCAACGAGAAATTGTCTGGAGAATAGGGTGGCTCTCA
GGTTATAAAACAATGGCTCCGAATTTCATCCGAAATCATGACACTATTCTGTTTTATTCGAAGAACTCAAGTAAAATTGA
GTTCATAAAGAAATATATTGAGAATAAGGATTTCAAGCCTTTGCTTAAGAAAGATGCAAAGGTGACGGCAAAGCTGAAAA
GCCTCGGTTTAAGCGACGAACAGCAGAAGGAACTTCTGGAATTTATTAATCATGGAAATCGACCAGAAAGATATCCGATA
GAGGATACATGGAATTCGAATGAGTATGATGATTTGAACAGCATTGCAATCGTCTCTTTTTCAGGAGAGAAAATCTCGAA
AATTCTCGATGTTGATCAGGATTTTAAAGGACAGAAGTCAGTGAAAATGCTGATGAGAATTATTGAGGCAACGACAAAAG
AAGATGACATCGTGATGGATTTCTTTTCCGGAACCGGATCAACGGCTCACGCTGTCATGCAGATGAATGCTGAAGATGGT
TGTCATAGGAAGTATATTATGGTGCAGCTTCCTGAACCGTGCGAAGATGGCGGCGCTGCTAAAGAAGCCGGATATGAGAA
TATCTGCGAGATTGGAAAGGAGCGAATTCGCAGGATTGGGCAGCGCATCAATGAATCTGCACCGTTGTTCGATTTGGATA
CTGGATTCAGAGTGTTCAAGGTTGCAGAAAGTAATATGAATGATGTTTATTATTCTGCTGGGGAATACAATCAGGGAATG
CTTTCGATGTTGGAGTCCAATGTGAAATCGGATCGTTCTGACCTCGATCTGCTATTTGGTTGCCTGCTTGAATGGGGATT
GCCGCTCTCGATGCCGTACACGTCAGAGCAGATTGAAGGCTGCACAGTTCACACATACAACGATGGCGATCTGATTGCCT
GCTTTGATGAGAACATTCCGGATTCTGTTATTAAAACTATCGCCAAGCGTCAGCCGCTCCGCGCAGTTTTTCGCGATAGC
AGCTTCGATGGAAGCCCGGCAAAGATCAACGTAGGGGAGATTTTCAAAATGTTGGCACCGGATACGAGGATCAAGGTGAT
TTAA

Upstream 100 bases:

>100_bases
TTCCTACAAGAGAAACTAAACGAGCTGAAGGGCAATGATGCAGAGTTTGAAAAAATTAGAATAGCTTATAAGAACAGAAA
CAAGCAGGAGGAAAGAGCTA

Downstream 100 bases:

>100_bases
ACGAGGAGGTGCCTATGATGTGGGTGATACGTGCCGGACAGAACTCCGGATTCTATGACAAATATTTGAGAACGAGCCGT
GTTTATATTCCTTGGGACGG

Product: type III restriction-modification system, methylase subunit

Products: NA

Alternate protein names: M.EcoP15I; EcoP15I methyltransferase [H]

Number of amino acids: Translated: 587; Mature: 587

Protein sequence:

>587_residues
MDKMRMESVDMTEKNIDRIAALFPNCITETVDEERSTPDKKVYKKAVNFELLRQMLSGDVLEGDEAYEFTWVGKKAAIVE
ANKPIRKTLRPCPEESVNWDSTENLYIEGDNLEVLKLIQESYMGKVKLIFIDPPYNTGSDFIYADDFAVGSAEYSDEIGE
VDADGNRLFKNTDSNGRFHSDWCSMMYSRLMLARNLLTDDGSIFISIDFNEVENLKKIMDEVFGAENFQREIVWRIGWLS
GYKTMAPNFIRNHDTILFYSKNSSKIEFIKKYIENKDFKPLLKKDAKVTAKLKSLGLSDEQQKELLEFINHGNRPERYPI
EDTWNSNEYDDLNSIAIVSFSGEKISKILDVDQDFKGQKSVKMLMRIIEATTKEDDIVMDFFSGTGSTAHAVMQMNAEDG
CHRKYIMVQLPEPCEDGGAAKEAGYENICEIGKERIRRIGQRINESAPLFDLDTGFRVFKVAESNMNDVYYSAGEYNQGM
LSMLESNVKSDRSDLDLLFGCLLEWGLPLSMPYTSEQIEGCTVHTYNDGDLIACFDENIPDSVIKTIAKRQPLRAVFRDS
SFDGSPAKINVGEIFKMLAPDTRIKVI

Sequences:

>Translated_587_residues
MDKMRMESVDMTEKNIDRIAALFPNCITETVDEERSTPDKKVYKKAVNFELLRQMLSGDVLEGDEAYEFTWVGKKAAIVE
ANKPIRKTLRPCPEESVNWDSTENLYIEGDNLEVLKLIQESYMGKVKLIFIDPPYNTGSDFIYADDFAVGSAEYSDEIGE
VDADGNRLFKNTDSNGRFHSDWCSMMYSRLMLARNLLTDDGSIFISIDFNEVENLKKIMDEVFGAENFQREIVWRIGWLS
GYKTMAPNFIRNHDTILFYSKNSSKIEFIKKYIENKDFKPLLKKDAKVTAKLKSLGLSDEQQKELLEFINHGNRPERYPI
EDTWNSNEYDDLNSIAIVSFSGEKISKILDVDQDFKGQKSVKMLMRIIEATTKEDDIVMDFFSGTGSTAHAVMQMNAEDG
CHRKYIMVQLPEPCEDGGAAKEAGYENICEIGKERIRRIGQRINESAPLFDLDTGFRVFKVAESNMNDVYYSAGEYNQGM
LSMLESNVKSDRSDLDLLFGCLLEWGLPLSMPYTSEQIEGCTVHTYNDGDLIACFDENIPDSVIKTIAKRQPLRAVFRDS
SFDGSPAKINVGEIFKMLAPDTRIKVI
>Mature_587_residues
MDKMRMESVDMTEKNIDRIAALFPNCITETVDEERSTPDKKVYKKAVNFELLRQMLSGDVLEGDEAYEFTWVGKKAAIVE
ANKPIRKTLRPCPEESVNWDSTENLYIEGDNLEVLKLIQESYMGKVKLIFIDPPYNTGSDFIYADDFAVGSAEYSDEIGE
VDADGNRLFKNTDSNGRFHSDWCSMMYSRLMLARNLLTDDGSIFISIDFNEVENLKKIMDEVFGAENFQREIVWRIGWLS
GYKTMAPNFIRNHDTILFYSKNSSKIEFIKKYIENKDFKPLLKKDAKVTAKLKSLGLSDEQQKELLEFINHGNRPERYPI
EDTWNSNEYDDLNSIAIVSFSGEKISKILDVDQDFKGQKSVKMLMRIIEATTKEDDIVMDFFSGTGSTAHAVMQMNAEDG
CHRKYIMVQLPEPCEDGGAAKEAGYENICEIGKERIRRIGQRINESAPLFDLDTGFRVFKVAESNMNDVYYSAGEYNQGM
LSMLESNVKSDRSDLDLLFGCLLEWGLPLSMPYTSEQIEGCTVHTYNDGDLIACFDENIPDSVIKTIAKRQPLRAVFRDS
SFDGSPAKINVGEIFKMLAPDTRIKVI

Specific function: Binds the system-specific DNA recognition site 5'- CAGCAC-3'. Necessary for both restriction and methylation (of one of the two A's) [H]

COG id: COG2189

COG function: function code L; Adenine specific DNA methylase Mod

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the N(4)/N(6)-methyltransferase family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002295
- InterPro:   IPR002941
- InterPro:   IPR002052 [H]

Pfam domain/function: PF01555 N6_N4_Mtase [H]

EC number: =2.1.1.72 [H]

Molecular weight: Translated: 66916; Mature: 66916

Theoretical pI: Translated: 4.54; Mature: 4.54

Prosite motif: PS00092 N6_MTASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
3.7 %Met     (Translated Protein)
5.3 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
3.7 %Met     (Mature Protein)
5.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDKMRMESVDMTEKNIDRIAALFPNCITETVDEERSTPDKKVYKKAVNFELLRQMLSGDV
CCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHCHHHHHHHHCCCC
LEGDEAYEFTWVGKKAAIVEANKPIRKTLRPCPEESVNWDSTENLYIEGDNLEVLKLIQE
CCCCCCEEEEEECCEEEEEECCCCHHHHHCCCCCCCCCCCCCCEEEEECCCHHHHHHHHH
SYMGKVKLIFIDPPYNTGSDFIYADDFAVGSAEYSDEIGEVDADGNRLFKNTDSNGRFHS
HCCCEEEEEEECCCCCCCCCEEEECCCCCCCCHHHHHCCCCCCCCCEEECCCCCCCCCHH
DWCSMMYSRLMLARNLLTDDGSIFISIDFNEVENLKKIMDEVFGAENFQREIVWRIGWLS
HHHHHHHHHHHHHHHHCCCCCCEEEEEEHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHC
GYKTMAPNFIRNHDTILFYSKNSSKIEFIKKYIENKDFKPLLKKDAKVTAKLKSLGLSDE
CCHHHCCHHHCCCCEEEEECCCCCHHHHHHHHHCCCCCCHHHHCCHHHHHHHHHCCCCCH
QQKELLEFINHGNRPERYPIEDTWNSNEYDDLNSIAIVSFSGEKISKILDVDQDFKGQKS
HHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCEEEEEECCHHHHHHHCCCCCCCCHHH
VKMLMRIIEATTKEDDIVMDFFSGTGSTAHAVMQMNAEDGCHRKYIMVQLPEPCEDGGAA
HHHHHHHHHHCCCCCCEEEEEECCCCCCEEEEEEECCCCCCCEEEEEEECCCCCCCCCCH
KEAGYENICEIGKERIRRIGQRINESAPLFDLDTGFRVFKVAESNMNDVYYSAGEYNQGM
HHCCHHHHHHHHHHHHHHHHHHHCCCCCEEECCCCCEEEEEECCCCCCEEEECCCCCHHH
LSMLESNVKSDRSDLDLLFGCLLEWGLPLSMPYTSEQIEGCTVHTYNDGDLIACFDENIP
HHHHHHHHHCCHHHHHHHHHHHHHCCCCCCCCCCHHHCCCCEEEEECCCCEEEEECCCCC
DSVIKTIAKRQPLRAVFRDSSFDGSPAKINVGEIFKMLAPDTRIKVI
HHHHHHHHHCCHHHHHHCCCCCCCCCCEEEHHHHHHHHCCCCEEEEC
>Mature Secondary Structure
MDKMRMESVDMTEKNIDRIAALFPNCITETVDEERSTPDKKVYKKAVNFELLRQMLSGDV
CCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHCHHHHHHHHCCCC
LEGDEAYEFTWVGKKAAIVEANKPIRKTLRPCPEESVNWDSTENLYIEGDNLEVLKLIQE
CCCCCCEEEEEECCEEEEEECCCCHHHHHCCCCCCCCCCCCCCEEEEECCCHHHHHHHHH
SYMGKVKLIFIDPPYNTGSDFIYADDFAVGSAEYSDEIGEVDADGNRLFKNTDSNGRFHS
HCCCEEEEEEECCCCCCCCCEEEECCCCCCCCHHHHHCCCCCCCCCEEECCCCCCCCCHH
DWCSMMYSRLMLARNLLTDDGSIFISIDFNEVENLKKIMDEVFGAENFQREIVWRIGWLS
HHHHHHHHHHHHHHHHCCCCCCEEEEEEHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHC
GYKTMAPNFIRNHDTILFYSKNSSKIEFIKKYIENKDFKPLLKKDAKVTAKLKSLGLSDE
CCHHHCCHHHCCCCEEEEECCCCCHHHHHHHHHCCCCCCHHHHCCHHHHHHHHHCCCCCH
QQKELLEFINHGNRPERYPIEDTWNSNEYDDLNSIAIVSFSGEKISKILDVDQDFKGQKS
HHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCEEEEEECCHHHHHHHCCCCCCCCHHH
VKMLMRIIEATTKEDDIVMDFFSGTGSTAHAVMQMNAEDGCHRKYIMVQLPEPCEDGGAA
HHHHHHHHHHCCCCCCEEEEEECCCCCCEEEEEEECCCCCCCEEEEEEECCCCCCCCCCH
KEAGYENICEIGKERIRRIGQRINESAPLFDLDTGFRVFKVAESNMNDVYYSAGEYNQGM
HHCCHHHHHHHHHHHHHHHHHHHCCCCCEEECCCCCEEEEEECCCCCCEEEECCCCCHHH
LSMLESNVKSDRSDLDLLFGCLLEWGLPLSMPYTSEQIEGCTVHTYNDGDLIACFDENIP
HHHHHHHHHCCHHHHHHHHHHHHHCCCCCCCCCCHHHCCCCEEEEECCCCEEEEECCCCC
DSVIKTIAKRQPLRAVFRDSSFDGSPAKINVGEIFKMLAPDTRIKVI
HHHHHHHHHCCHHHHHHCCCCCCCCCCEEEHHHHHHHHCCCCEEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 2837577 [H]