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The map label for this gene is pyrR

Identifier: 57234051

GI number: 57234051

Start: 1093541

End: 1094089

Strand: Direct

Name: pyrR

Synonym: DET1198

Alternate gene names: 57234051

Gene position: 1093541-1094089 (Clockwise)

Preceding gene: 57234052

Following gene: 57234050

Centisome position: 74.4

GC content: 51.0

Gene sequence:

>549_bases
ATGGCACAAAAAGTAATACTGGGCGCCGAAGATATCCGCCGCACTCTGGCCCGTATTGCCCATGAAATACTGGAAAGAAA
CCATTCCAGCCGTGACCTTGTTATTATCGGCATGTATACCCGGGGCGTACCTCTGGCAAACCGCCTGGCCGAAAATATCC
TCCGCTTTGAAGGGCTGGAAATACCGGTGGGGACACTGGACTTTTCACTCTACCGTGATGACCTTGATTCCCAGCGTTTC
CACCCCACCATCAAAAATACTGACATACCTTTCAGCATAAACAACAAAATAGTGGTACTGGTAGATGACGTCCTCTTTAC
CGGGCGTTCCACCCGGGCGGCTATGGATGCCCTGATAGATTACGGACGCCCCAAAGCTATCCAGCTGGCAGTGCTGGTAG
ACAGAGGCCACCGCGAACTGCCGGTACGGGCGGATTATATAGGCAAGAATATACCCAGCTCACGTGACGAGAAGATAAAA
GTACGCCTGACCGAAACAGACGGACGGGACGAAATACTTATACTGGATAATGAAGCAGGTGAGGTATAA

Upstream 100 bases:

>100_bases
AGGGTTACCTTTAAGCTGGTCCTGAGAGGCCGGTAAGGGATTTTAGACAAAGAAGTGTCTTTTGACCTCTTGCCGGCAAA
TGTTGGTAAGAGGTTTTTTT

Downstream 100 bases:

>100_bases
ACATGACGAACACCCCCAAAACCCCCGCAGAAACTGAAACCCTGCTTTCCGAGGTACAGGGCTGGAAACACCGCCATGTG
CTGGATTTAGATAACTTCAG

Product: bifunctional pyrimidine regulatory protein PyrR uracil phosphoribosyltransferase

Products: NA

Alternate protein names: Pyrimidine operon regulatory protein; Uracil phosphoribosyltransferase; UPRTase

Number of amino acids: Translated: 182; Mature: 181

Protein sequence:

>182_residues
MAQKVILGAEDIRRTLARIAHEILERNHSSRDLVIIGMYTRGVPLANRLAENILRFEGLEIPVGTLDFSLYRDDLDSQRF
HPTIKNTDIPFSINNKIVVLVDDVLFTGRSTRAAMDALIDYGRPKAIQLAVLVDRGHRELPVRADYIGKNIPSSRDEKIK
VRLTETDGRDEILILDNEAGEV

Sequences:

>Translated_182_residues
MAQKVILGAEDIRRTLARIAHEILERNHSSRDLVIIGMYTRGVPLANRLAENILRFEGLEIPVGTLDFSLYRDDLDSQRF
HPTIKNTDIPFSINNKIVVLVDDVLFTGRSTRAAMDALIDYGRPKAIQLAVLVDRGHRELPVRADYIGKNIPSSRDEKIK
VRLTETDGRDEILILDNEAGEV
>Mature_181_residues
AQKVILGAEDIRRTLARIAHEILERNHSSRDLVIIGMYTRGVPLANRLAENILRFEGLEIPVGTLDFSLYRDDLDSQRFH
PTIKNTDIPFSINNKIVVLVDDVLFTGRSTRAAMDALIDYGRPKAIQLAVLVDRGHRELPVRADYIGKNIPSSRDEKIKV
RLTETDGRDEILILDNEAGEV

Specific function: Displays also a weak uracil phosphoribosyltransferase activity which is not physiologically significant

COG id: COG2065

COG function: function code F; Pyrimidine operon attenuation protein/uracil phosphoribosyltransferase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the purine/pyrimidine phosphoribosyltransferase family. PyrR subfamily

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): PYRR_DEHE1 (Q3Z788)

Other databases:

- EMBL:   CP000027
- RefSeq:   YP_181911.1
- HSSP:   P65941
- ProteinModelPortal:   Q3Z788
- SMR:   Q3Z788
- STRING:   Q3Z788
- GeneID:   3229517
- GenomeReviews:   CP000027_GR
- KEGG:   det:DET1198
- NMPDR:   fig|243164.3.peg.1090
- TIGR:   DET1198
- eggNOG:   COG2065
- HOGENOM:   HBG641958
- OMA:   ILDITLY
- ProtClustDB:   PRK05205
- BioCyc:   DETH243164:DET_1198-MONOMER
- GO:   GO:0006350
- HAMAP:   MF_01219
- InterPro:   IPR000836
- InterPro:   IPR023050

Pfam domain/function: PF00156 Pribosyltran

EC number: =2.4.2.9

Molecular weight: Translated: 20557; Mature: 20426

Theoretical pI: Translated: 6.14; Mature: 6.14

Prosite motif: PS00103 PUR_PYR_PR_TRANSFER

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
1.6 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.1 %Met     (Mature Protein)
1.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAQKVILGAEDIRRTLARIAHEILERNHSSRDLVIIGMYTRGVPLANRLAENILRFEGLE
CCCEEEECHHHHHHHHHHHHHHHHHCCCCCCCEEEEEEECCCCCHHHHHHHHHHHHCCCC
IPVGTLDFSLYRDDLDSQRFHPTIKNTDIPFSINNKIVVLVDDVLFTGRSTRAAMDALID
CCCCCEEHEEECCCCCCCCCCCCCCCCCCCEEECCEEEEEEECEEECCCCHHHHHHHHHH
YGRPKAIQLAVLVDRGHRELPVRADYIGKNIPSSRDEKIKVRLTETDGRDEILILDNEAG
CCCCCEEEEEEEEECCCCCCCEEHHHHCCCCCCCCCCEEEEEEECCCCCCEEEEEECCCC
EV
CC
>Mature Secondary Structure 
AQKVILGAEDIRRTLARIAHEILERNHSSRDLVIIGMYTRGVPLANRLAENILRFEGLE
CCEEEECHHHHHHHHHHHHHHHHHCCCCCCCEEEEEEECCCCCHHHHHHHHHHHHCCCC
IPVGTLDFSLYRDDLDSQRFHPTIKNTDIPFSINNKIVVLVDDVLFTGRSTRAAMDALID
CCCCCEEHEEECCCCCCCCCCCCCCCCCCCEEECCEEEEEEECEEECCCCHHHHHHHHHH
YGRPKAIQLAVLVDRGHRELPVRADYIGKNIPSSRDEKIKVRLTETDGRDEILILDNEAG
CCCCCEEEEEEEEECCCCCCCEEHHHHCCCCCCCCCCEEEEEEECCCCCCEEEEEECCCC
EV
CC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA