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The map label for this gene is cobA-3 [H]

Identifier: 57234042

GI number: 57234042

Start: 1123305

End: 1123850

Strand: Direct

Name: cobA-3 [H]

Synonym: DET1224

Alternate gene names: 57234042

Gene position: 1123305-1123850 (Clockwise)

Preceding gene: 57234044

Following gene: 57234041

Centisome position: 76.43

GC content: 51.83

Gene sequence:

>546_bases
TTGGTAACAAACCATACCCCTTACCTTGAAAAAGGCCTTATATCCATATTCACCGGTGAAGGCAAGGGTAAGACCTCGGC
TGCAGTCGGCACTGCTATCAGGGCTGCCGGTCACGGGCTGAGGGTTTGCCTCATTTTTTTTGCCAAAGGAAAACGTTTTG
ACCACGGCGAATTTAAAATATTGTCTTCCCTGCCGAATGTAACTTTGCAAAGCTTCGGCCAGGCCGGCTGGATACTCAAA
AATATATCCGAAGAAACCCGCACACAGGCGGAACGGGCTTTTGAGACCGCCTCCGAAGCGGTAACCGGCGGGCAGTATGA
CCTGGTAGTCATGGACGAAATCATGATAGCCCTGACGGCCGGGCTGGTCACCACCGAACAGGTTATCCGGATGATAAACG
CCAAACCGCCCTGCGTAGAGCTGATTATGACCGGGCGGGGCGCCCCGGCTGAACTTATAGAACTGGCTGACCTGGTTTCG
GAAATAAAGGCAGTCAAACACCCGTATACTAGGGGCATCAAAGCCCGTAAAGGTATAGATTACTAA

Upstream 100 bases:

>100_bases
GCCTGAGCCAAGCAGAAATACCCGGAGTTTGGCTTGACAGTCCCGTATGCCACTGTTAAACTTTATCTTCGGCGCTAGGC
CGTATGTTGGGAGGATTTTT

Downstream 100 bases:

>100_bases
TCTTCACCAAGGAGAAAATAATGAAAGTAACCCTTAGTGTTATTAAAGCAGATATCGGCGGTTTTGTAGGCCATTCGGAC
TCACACCCGCAGTGTCTGGT

Product: cob(I)alamin adenosyltransferase

Products: NA

Alternate protein names: Cob(I)alamin adenosyltransferase; Corrinoid adenosyltransferase [H]

Number of amino acids: Translated: 181; Mature: 181

Protein sequence:

>181_residues
MVTNHTPYLEKGLISIFTGEGKGKTSAAVGTAIRAAGHGLRVCLIFFAKGKRFDHGEFKILSSLPNVTLQSFGQAGWILK
NISEETRTQAERAFETASEAVTGGQYDLVVMDEIMIALTAGLVTTEQVIRMINAKPPCVELIMTGRGAPAELIELADLVS
EIKAVKHPYTRGIKARKGIDY

Sequences:

>Translated_181_residues
MVTNHTPYLEKGLISIFTGEGKGKTSAAVGTAIRAAGHGLRVCLIFFAKGKRFDHGEFKILSSLPNVTLQSFGQAGWILK
NISEETRTQAERAFETASEAVTGGQYDLVVMDEIMIALTAGLVTTEQVIRMINAKPPCVELIMTGRGAPAELIELADLVS
EIKAVKHPYTRGIKARKGIDY
>Mature_181_residues
MVTNHTPYLEKGLISIFTGEGKGKTSAAVGTAIRAAGHGLRVCLIFFAKGKRFDHGEFKILSSLPNVTLQSFGQAGWILK
NISEETRTQAERAFETASEAVTGGQYDLVVMDEIMIALTAGLVTTEQVIRMINAKPPCVELIMTGRGAPAELIELADLVS
EIKAVKHPYTRGIKARKGIDY

Specific function: Required for both de novo synthesis of the corrin ring for the assimilation of exogenous corrinoids. Participates in the adenosylation of a variety of incomplete and complete corrinoids [H]

COG id: COG2109

COG function: function code H; ATP:corrinoid adenosyltransferase

Gene ontology:

Cell location: Cytoplasm (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the Cob(I)alamin adenosyltransferase family [H]

Homologues:

Organism=Escherichia coli, GI1787525, Length=173, Percent_Identity=38.150289017341, Blast_Score=114, Evalue=3e-27,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003724 [H]

Pfam domain/function: PF02572 CobA_CobO_BtuR [H]

EC number: =2.5.1.17 [H]

Molecular weight: Translated: 19593; Mature: 19593

Theoretical pI: Translated: 8.70; Mature: 8.70

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVTNHTPYLEKGLISIFTGEGKGKTSAAVGTAIRAAGHGLRVCLIFFAKGKRFDHGEFKI
CCCCCCCHHHHCCEEEEECCCCCCHHHHHHHHHHHCCCCHHHHHEEECCCCCCCCCHHHH
LSSLPNVTLQSFGQAGWILKNISEETRTQAERAFETASEAVTGGQYDLVVMDEIMIALTA
HHHCCCHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEHHHHHHHHHHHH
GLVTTEQVIRMINAKPPCVELIMTGRGAPAELIELADLVSEIKAVKHPYTRGIKARKGID
HHHHHHHHHHHHCCCCCCEEEEECCCCCHHHHHHHHHHHHHHHHHHCHHHHCCCCCCCCC
Y
C
>Mature Secondary Structure
MVTNHTPYLEKGLISIFTGEGKGKTSAAVGTAIRAAGHGLRVCLIFFAKGKRFDHGEFKI
CCCCCCCHHHHCCEEEEECCCCCCHHHHHHHHHHHCCCCHHHHHEEECCCCCCCCCHHHH
LSSLPNVTLQSFGQAGWILKNISEETRTQAERAFETASEAVTGGQYDLVVMDEIMIALTA
HHHCCCHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEHHHHHHHHHHHH
GLVTTEQVIRMINAKPPCVELIMTGRGAPAELIELADLVSEIKAVKHPYTRGIKARKGID
HHHHHHHHHHHHCCCCCCEEEEECCCCCHHHHHHHHHHHHHHHHHHCHHHHCCCCCCCCC
Y
C

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12471157 [H]